Geriatrics Commons^™

Determining Risk Of Falls In Community-Dwelling Older Adults: A Systematic Review And Meta-Analysis Using Posttest Probability, Michelle M. Lusardi, Stacy Fritz, Addie Middletown, Leslie Allison, Mariana Wingood, Emma Phillips, Michelle Criss, Sangita Verma, Jackie Osborne, Kevin Chui

All PTHMS Faculty Publications

BACKGROUND:

Falls and their consequences are significant concerns for older adults, caregivers, and health care providers. Identification of fall risk is crucial for appropriate referral to preventive interventions. Falls are multifactorial; no single measure is an accurate diagnostic tool. There is limited information on which history question, self-report measure, or performance-based measure, or combination of measures, best predicts future falls.

PURPOSE:

First, to evaluate the predictive ability of history questions, self-report measures, and performance-based measures for assessing fall risk of community-dwelling older adults by calculating and comparing posttest probability (PoTP) values for individual test/measures. Second, to evaluate usefulness of cumulative …

Healthy Aging Website: Providing Online Occupation Based Information, Haley Caruthers, Samantha Talavera, Stephanie Vera, Jackeline Ulloa

Student Research Posters

Older adults (OAs) over the age of 65 are the fastest growing age group in the United States. They are also the fastest growing population of Internet users as they use the Internet to access health information related to optimizing independence, productivity, and social engagement. Although there is an abundant amount of information available that is devoted to healthy aging, the validity of the information can be questionable and the information may be confusing.

Dominican University of California’s (DUC) Healthy Aging website contains relevant and evidence-based research, including activities and local community based programs that promote healthy aging. To expand …

Regulation Of Core Body Temperature And The Immune System Determines Species Longevity, Ian J. Martins

Research outputs 2014 to 2021

The anti-aging gene Sirtuin 1 has now major relevance to genetics and the fields of pharmacology, toxicology, neuroscience, immunology, biochemistry and cell/molecular biology. Advances in anti-aging therapy are now essential to prevent mitochondrial apoptosis to promote longevity with the prevention of accelerated ageing. Calorie restriction that maintains the anti-aging gens changes the core body temperature and promotes species longevity. Stress and calorie consumption are sensitive to Sirt 1 function with relevance heat shock protein 70 metabolism and mitochondrial biogenesis. Sirt 1 regulation of the circadian rhythm mediates melatonin effects on core body temperature regulation and immune responses. Diet and fat …

Amyloid Β–Associated Cognitive Decline In The Absence Of Clinical Disease Progression And Systemic Illness, Karra Harrington, Yen Lim, David Ames, Jason Hassenstab, Simon Laws, Ralph Martins, Stephanie Rainey-Smith, Joanne Robertson, Christopher Rowe, Olivier Salvado, Vincent Dore, Victor Villemagne, Peter Snyder, Colin Masters, Paul Maruff, Aibl Research Group

Research outputs 2014 to 2021

Introduction

High levels of amyloid β (Aβ) are associated with cognitive decline in cognitively normal (CN) older adults. This study investigated the nature of cognitive decline in healthy individuals who did not progress to mild cognitive impairment or dementia.

Method

Cognition was measured over 72 months and compared between low (Aβ−) and high (Aβ+) CN older adults (n = 335) who did not progress to mild cognitive impairment or dementia and who remained free of severe or uncontrolled systemic illness.

Results

Compared to the Aβ− group, the Aβ+ group showed no cognitive impairment at baseline but showed substantial decline …