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Articles 121 - 123 of 123
Full-Text Articles in Geriatrics
Neuroprotective Action Of Cycloheximide Involves Induction Of Bcl-2 And Antioxidant Pathways, Katsutoshi Furukawa, Steven Estus, Weiming Fu, Robert J. Mark, Mark P. Mattson
Neuroprotective Action Of Cycloheximide Involves Induction Of Bcl-2 And Antioxidant Pathways, Katsutoshi Furukawa, Steven Estus, Weiming Fu, Robert J. Mark, Mark P. Mattson
Sanders-Brown Center on Aging Faculty Publications
The ability of the protein synthesis inhibitor cycloheximide (CHX) to prevent neuronal death in different paradigms has been interpreted to indicate that the cell death process requires synthesis of “killer” proteins. On the other hand, data indicate that neurotrophic factors protect neurons in the same death paradigms by inducing expression of neuroprotective gene products. We now provide evidence that in embryonic rat hippocampal cell cultures, CHX protects neurons against oxidative insults by a mechanism involving induction of neuroprotective gene products including the antiapoptotic gene bcl-2 and antioxidant enzymes. Neuronal survival after exposure to glutamate, FeSO4, and amyloid β-peptide …
Book Review, Mitchell M. Simon
Book Review, Mitchell M. Simon
RISK: Health, Safety & Environment (1990-2002)
Review of: MARSHALL A. KAPP, ETHICAL ASPECTS OF HEALTH CARE FOR THE ELDERLY: AN ANNOTATED BIBLIOGRAPHY. (Greenwood Press 1992). [200 pp.] Number 17 in series, Bibliographies and Indices in Gerontology. Author index; foreword by Erdman B. Palmore, series editor; preface; subject index. LC: 92-17776; ISBN: 0-313-27490-8. [Cloth $45.00. P.O. Box 5007, Westport CT 06881.]
Ethnicity And Lifetimes: Self Concepts And Situational Contexts Of Ethnic Identity In Late Life, Mark Luborsky, Robert L. Rubinstein
Ethnicity And Lifetimes: Self Concepts And Situational Contexts Of Ethnic Identity In Late Life, Mark Luborsky, Robert L. Rubinstein
Anthropology Faculty Research Publications
This chapter reports on finding from a study of ethnic older men, aged 65 an older (Jewish, Irish, and Italian) who were widowed from 2 to 8 years after a long-term study. It focuses on life reorganization after the initial bereavement period. It identifies key issues in the process concerning continuity and change in identity reformulation, changes in health and activity patterns, ethnic identity and lingering attachment to the deceased spouse. Ethnicity as a dynamic life course process, shaped by contextual and historical dimensions, and personal meaning processes are highlighted. Supported by NIH# R01-AG005204