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Articles 1 - 8 of 8
Full-Text Articles in Aerospace Medicine
Impact Of Stress & Fatigue On Cardiovascular Function In Young Pilots: A Thematic Review, Swarna Manoj
Impact Of Stress & Fatigue On Cardiovascular Function In Young Pilots: A Thematic Review, Swarna Manoj
Discovery Day - Daytona Beach
Impact of Stress & Fatigue on Cardiovascular Function in Young Pilots: A Thematic Review Authors: Swarna Manoj, Scott Ferguson Keywords: pilot, stress, fatigue, heart rate variability (HRV), cardiovascular disease (CVD) Aviation is expanding globally and young pilots are the major workforce, yet FAA protocols require mandatory ECG only from age 35, with annual cardiac screening after age 40. Over the past five years, a pattern of sudden cardiac arrests in pilots particularly aged 30-40 has urged safety concerns. Despite the existing literature examining fatigue, burnout, stress, sleep hygiene and circadian disruption, only few studies systematically examine how these factors impact …
Assessing The Impact Of Various Factors On Hypoxic Response, Reese Kim, Allysa Hayden
Assessing The Impact Of Various Factors On Hypoxic Response, Reese Kim, Allysa Hayden
Discovery Day - Daytona Beach
Hypoxia is a condition in which the body’s tissues are deprived of oxygen and has deleterious effects on cognition, perception, and performance. Hypoxia has a myriad of symptoms such as euphoria, difficulty concentrating, headache, fatigue, nausea, dizziness, tunnel vision, and more. Outward signs of hypoxia include cyanosis (blueing of the fingertips and lips), tremors, loss of coordination, pallor, and complexion change, and can be used to notice the onset of hypoxia in others. Many factors are known to contribute to the manifestation of hypoxia, namely altitude, exposure duration, and certain physiological conditions such as heart problems and low blood flow …
Gene Therapy Strategies To Enhance Antifungal Immunity In Microgravity, Riley Dienna
Gene Therapy Strategies To Enhance Antifungal Immunity In Microgravity, Riley Dienna
Discovery Day - Daytona Beach
During spaceflight, the immune system of astronauts becomes impaired due to microgravity, resulting in increased susceptibility to infections caused by pathogens such as Candida albicans. One of the most common clinical treatments for aggressive candidiasis is amphotericin B, a polyene antimycotic that targeted ergosterol in the fungal cell membrane and compromised the stability of the membrane. However, due to the chemical similarities between ergosterol and cholesterol, this treatment also affects the somatic cells of patients it is administered to. A novel treatment is therefore required to combat the aggressive fungal infection while minimizing damage to the host’s cells. This project …
Using H2ax As A Biological Indicator To Assess Radiation-Induced Bone Loss In Microgravity Environments, Angeline Nichols, Enoch Tonkin, Ana Lobaton, Jahzara Hope
Using H2ax As A Biological Indicator To Assess Radiation-Induced Bone Loss In Microgravity Environments, Angeline Nichols, Enoch Tonkin, Ana Lobaton, Jahzara Hope
Discovery Day - Daytona Beach
Long-duration space missions expose astronauts to microgravity and chronic low-dose radiation, both greatly impacting skeletal health. While mechanical unloading in microgravity is a well-known driver of bone loss, recent evidence indicates that radiation independently contributes to bone deterioration by increasing osteoclast activity, which remodel bone faster, and suppress osteoblast differentiation. H2AX, a histone protein that rapidly phosphorylates into y-H2AX in response to the double strands of DNA breaking, has emerged as a sensitive biological marker for radiation exposure. This project aims to determine the efficacy of H2AX in the presence of radiation-induced DNA damage in bone marrow, compared to microgravity …
Analysis Of Non-Thermal Plasma’S Effects On Melanoma: A Biological Examination, Violet Ochrietor, Mia Nilsen, Arden Rodriguez, Ally Schwennesen
Analysis Of Non-Thermal Plasma’S Effects On Melanoma: A Biological Examination, Violet Ochrietor, Mia Nilsen, Arden Rodriguez, Ally Schwennesen
Discovery Day - Daytona Beach
Melanoma is a serious form of skin cancer that may present as a real and increased risk during long-term spaceflight due to radiation exposure and limited treatment options. Non-Thermal Plasma (NTP) has emerged as a promising therapeutic tool due to its ability to generate reactive oxygen and nitrogen species (ROS and RNS) that affect cellular functioning without causing temperature related damage to surrounding tissues. This project investigates the effects of NTP on melanoma cells through a biological examination of exposure time, frequency of plasma, and cellular growth conditions. Human melanoma cells and keratinocytes will be cultured and exposed to the …
The Effect Of Snris On Pilot Reaction Time In Simulated Flight, Isabella Owen, Aidan Roach, Micah Henry, Casey Tressler
The Effect Of Snris On Pilot Reaction Time In Simulated Flight, Isabella Owen, Aidan Roach, Micah Henry, Casey Tressler
Discovery Day - Daytona Beach
Many aviators who are prescribed serotonin and norepinephrine reuptake inhibitors (SNRI) or selective serotonin reuptake inhibitors (SSRI) to treat mental health disorders such as major depressive disorder, general anxiety disorder, or post-traumatic stress disorder must halt their duties for a set amount of time. This is due to aviation authorities having data that suggests SNRIs and SSRIs lead to inhibitions in mental processes that can cause crashes or death. Most of the research that has been conducted examined the effects of SSRIs on individuals without mental health disorders in non-flight settings. This study will explore the effect SNRIs have on …
Effects Of Microgravity And Gamma Radiation On Biofilm Growth, Anya Pavlidis, Kaitlyn Mills Mills, Eva Mcclory, Grant Erlinder, Allen Qiu
Effects Of Microgravity And Gamma Radiation On Biofilm Growth, Anya Pavlidis, Kaitlyn Mills Mills, Eva Mcclory, Grant Erlinder, Allen Qiu
Discovery Day - Daytona Beach
Biofilms are collections of bacteria that commonly grow on a variety of surfaces. They are resistant to environmental impacts as bacteria fortify themselves to a surface. Biofilms are commonly found on Earth, but more problematically are also found on spacecraft. On the ISS biofilms have developed in spaces like the workout area, food spaces, and most concerning in the Water Recovery System (WRS). Biofilms tend to react differently to attempted cleaning methods in space than they do on Earth and can be located in extremely difficult to reach places. This study aims to explore the effects of gamma radiation on …
Effects Of Sleep Duration And Perceived Stress Of Reaction Time In Undergraduate Students, Caitlin Wescott, Edna Urrutia, Ryan F. Rednick, David Still
Effects Of Sleep Duration And Perceived Stress Of Reaction Time In Undergraduate Students, Caitlin Wescott, Edna Urrutia, Ryan F. Rednick, David Still
Discovery Day - Daytona Beach
Sleep deprivation and psychological stress are common among undergraduate students and can negatively affect cognitive performance. Reaction time is an important indicator of attention and processing speed and plays a critical role in both everyday activities, such as driving, and high-performance environments where rapid responses are required. This study aims to examine how sleep duration and perceived stress levels influence reaction time in undergraduate students. Participants will report their sleep duration and perceived stress levels through short surveys and wearable sleep data, while reaction time will be measured using a standardized computerized reaction time test. By comparing reaction time across …