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Articles 1 - 3 of 3
Full-Text Articles in Aerospace Medicine
Sex-Dependent Changes In Risk-Taking Predisposition Of Rats Following Space Radiation Exposure, Elliot Smits, Faith E. Reid, Ella N. Tamgue, Paola Alvarado Arriaga, Charles Nguyen, Richard A. Britten
Sex-Dependent Changes In Risk-Taking Predisposition Of Rats Following Space Radiation Exposure, Elliot Smits, Faith E. Reid, Ella N. Tamgue, Paola Alvarado Arriaga, Charles Nguyen, Richard A. Britten
Department Radiation Oncology & Biophysics Faculty Publications
The Artemis missions will establish a sustainable human presence on the Moon, serving as a crucial steppingstone for future Mars exploration. Astronauts on these ambitious missions will have to successfully complete complex tasks, which will frequently involve rapid and effective decision making under unfamiliar or high-pressure conditions. Exposure to low doses of space radiation (SR) can impair key executive functions critical to decision making. This study examined the effects of exposure to 10 cGy of Galactic Cosmic Ray simulated radiation (GCRsim) on decision-making performance in male and female rats with a naturally low predisposition for risk-taking (RTP) prior to exposure. …
Exposure To Low (10 Cgy) Doses Of ⁴He Ions Leads To An Apparent Increase In Risk Taking Propensity In Female Rats, Nina Li, Simran Phuyal, Elliot Smits, Faith E. Reid, Ella N. Tamgue, Paola Alvarado Arriaga, Richard A. Britten
Exposure To Low (10 Cgy) Doses Of ⁴He Ions Leads To An Apparent Increase In Risk Taking Propensity In Female Rats, Nina Li, Simran Phuyal, Elliot Smits, Faith E. Reid, Ella N. Tamgue, Paola Alvarado Arriaga, Richard A. Britten
Department of Medicine Faculty Publications
The planned missions to the Moon and Mars will present more significant health challenges to astronauts compared to low earth orbit missions. During deep space missions, astronauts will be constantly exposed to Space radiation (SR). Multiple rodent studies suggest that < 25 cGy of SR impairs performance in executive functions, which play a key role in advanced cognitive processes, but also regulate response inhibition and impulse control. There is the possibility that SR exposure may exacerbate aberrant behaviors evoked by psychological stress related to exposure to isolated and confined (ICE) hostile environment or independently induce additional aberrant behaviors. This study has determined that female Wistar rats exposed to 10 cGy of 250 MeV/n He had an increased risk taking propensity (RTP)\compared to shams. The increased RTP of the He-exposed rats was associated with significantly increased reaction times during the trials, suggesting a SR-induced loss of processing speed. The response times of the He-exposed rats were even further reduced in trials that immediately followed a loss, raising the possibility that conflict and interference avoidance may be impaired after SR exposure. Whether these findings occur following other types of SR exposure, and/or in male rats remains to be determined.
Utilizing The System Engineering Trade Study Analysis Method To Analyze Patient Aeromedical Evacuation, Sara Shaghaghi, Jeremy M. Slagley, Michael E. Miller, Gaiven Varshney
Utilizing The System Engineering Trade Study Analysis Method To Analyze Patient Aeromedical Evacuation, Sara Shaghaghi, Jeremy M. Slagley, Michael E. Miller, Gaiven Varshney
Faculty Publications
The US Air Force has gone through many aeromedical patient isolation transport system designs. The first designs were developed in response to the Ebola outbreak in 2014 and, more recently, the COVID-19 pandemic. The trade study analysis part of the system engineering design method was used to analyze the historic and current aeromedical patient contamination control transport systems. A trade study is a process that evaluates alternatives based upon various “-ilities”, such as reconfigurability, flexibility, durability, cost, and more, and performs a systematic analysis to aid designers in producing a ‘good’ design alternative given the large set of possible solutions. …