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2020

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Articles 2371 - 2400 of 4794

Full-Text Articles in Medical Specialties

Investigating Birth Outcomes Among Deaf Mothers: Hospital Vs. Home Births, Aashni Kamra May 2020

Investigating Birth Outcomes Among Deaf Mothers: Hospital Vs. Home Births, Aashni Kamra

Undergraduate University Honors Capstones

This study examined birth outcomes among Deaf mothers who have given birth in a hospital setting versus a home setting. Deaf individuals are often marginalized in healthcare due to lack of accessibility, and therefore, the right to make their own informed decisions. This marginalization leads to inequality in health care, and oftentimes individuals within the Deaf community, with added intersectionalities, face even more discrimination. Deaf women face more health disparities in comparison to hearing women due to a variety of factors which include; lack of accessibility, medical professionals’ lack of cultural competency, and lack of inclusion in their healthcare decisions. …


Allosteric Inhibitor Of Β-Catenin Selectively Targets Oncogenic Wnt Signaling In Colon Cancer., Anton Cheltsov, Natsuko Nomura, Venkata Mahidhar Yenugonda, Jatin Roper, Rajesh Mukthavaram, Pengfei Jiang, Nam-Gu Her, Ivan Babic, Santosh Kesari, Elmar Nurmemmedov May 2020

Allosteric Inhibitor Of Β-Catenin Selectively Targets Oncogenic Wnt Signaling In Colon Cancer., Anton Cheltsov, Natsuko Nomura, Venkata Mahidhar Yenugonda, Jatin Roper, Rajesh Mukthavaram, Pengfei Jiang, Nam-Gu Her, Ivan Babic, Santosh Kesari, Elmar Nurmemmedov

Articles, Abstracts, and Reports

Abnormal regulation of β-catenin initiates an oncogenic program that serves as a main driver of many cancers. Albeit challenging, β-catenin is an attractive drug target due to its role in maintenance of cancer stem cells and potential to eliminate cancer relapse. We have identified C2, a novel β-catenin inhibitor, which is a small molecule that binds to a novel allosteric site on the surface of β-catenin. C2 selectively inhibits β-catenin, lowers its cellular load and significantly reduces viability of β-catenin-driven cancer cells. Through direct binding to β-catenin, C2 renders the target inactive that eventually activates proteasome system for its removal. …


Atrioventricular Nodal Reentrant Tachycardia In Patients With Complex Congenital Heart Disease And Twin Atrioventricular Nodes., John Papagiannis, Christopher Mathis, Lindsey Malloy-Walton, Svjetlana Tisma-Dupanovic May 2020

Atrioventricular Nodal Reentrant Tachycardia In Patients With Complex Congenital Heart Disease And Twin Atrioventricular Nodes., John Papagiannis, Christopher Mathis, Lindsey Malloy-Walton, Svjetlana Tisma-Dupanovic

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.


A Battle For Hope, Kaline E. Mulvihill May 2020

A Battle For Hope, Kaline E. Mulvihill

Akesis

I have friends and family members working in all aspects of the medical system. They are PAs, PTs, nurses, doctors, caregivers, and support staff. They are on the frontline in the brutal battle against Covid-19. This is their story. It is a story about fear, duty, strength, and finding hope. While we adapt to this new normal and cope with the ever-changing landscape, we have to remember that we are all in this fight together.


No Sneezing In Public, Anonymous Author May 2020

No Sneezing In Public, Anonymous Author

Akesis

Poetry relating to compassion during COVID-19 pandemic


Broken With Nature, Meghan Bowler May 2020

Broken With Nature, Meghan Bowler

Akesis

This is a short reflection on two separate periods of intense mental and physical self-healing. Nature removed me from the imprisonment of my own mind around 8 years ago, only to fall back into its grips after a recent hip surgery. Hiking/physical activity was the only form of therapy that I was vulnerable enough to let heal me. It would break me down mentally and physically while rebuilding me at the same time. Some information was derived from personal journal entries but all are very relevant to each and every hike I take today.


Tides, Paul S. Eo May 2020

Tides, Paul S. Eo

Akesis

This photo is an overhead shot of the waves breaking at Pine Point beach. This represents so much for me. In these times of uncertainty it gives me hope that the tides will eventually turn. And just like the tides, this too will take a turn for the better. It also represents the healing and cleansing qualities of the sea.


Motus Habitus: An Anatomical Ethnography, Michael Cyr, Jordan G. Lamb May 2020

Motus Habitus: An Anatomical Ethnography, Michael Cyr, Jordan G. Lamb

Akesis

Although this project began long before the release of Akesis' Spring theme, it perfectly encapsulates adaptation in many ways. The response to the recent pandemic and the disruption to people's daily routines has caused us to reflect on the ways we experience our bodies and minds in the absence of work, recreation, sociality, and movement. Movement, a key to human health and happiness, has been greatly restrained as most of us are confined to our living quarters. Now more than ever it is important to acknowledge the effects of lifestyle on body and health and find creative ways to move …


Decision 2020, Rolene Yousefyan May 2020

Decision 2020, Rolene Yousefyan

Akesis

The materials used to create this piece were chalk pastels. The inspiration behind this drawing was the difficult decisions we all have had to make at some point throughout our lives. No matter the reason why we made these decisions, there is no changing them and they may forever change the pathways of our lives.


Provider Education And Rapid Antigen Detection Test Use In Private And Academic Pediatric Clinics, Steven Dahl May 2020

Provider Education And Rapid Antigen Detection Test Use In Private And Academic Pediatric Clinics, Steven Dahl

Research Days

No abstract provided.


Neurally Adjusted Ventilatory Assist In Neonates With Congenital Diaphragmatic Hernia, Yonatan Kurland May 2020

Neurally Adjusted Ventilatory Assist In Neonates With Congenital Diaphragmatic Hernia, Yonatan Kurland

Research Days

No abstract provided.


The Impact Of Botox For Hospitalized Patients With Hirschsprung Associated Enterocolitis, Wendy J. Svetanoff, Obiyo O. Osuchukwu May 2020

The Impact Of Botox For Hospitalized Patients With Hirschsprung Associated Enterocolitis, Wendy J. Svetanoff, Obiyo O. Osuchukwu

Research Days

No abstract provided.


Optimal Treatment Of Pediatric Breast Abscesses: A Retrospective Analysis, Charlene Dekonenko, Obiyo O. Osuchukwu May 2020

Optimal Treatment Of Pediatric Breast Abscesses: A Retrospective Analysis, Charlene Dekonenko, Obiyo O. Osuchukwu

Research Days

No abstract provided.


Characteristics Of Low Acuity Unscheduled Transfers To The Pediatric Intensive Care Unit, Ashley Daniel May 2020

Characteristics Of Low Acuity Unscheduled Transfers To The Pediatric Intensive Care Unit, Ashley Daniel

Research Days

No abstract provided.


Diagnosis Of Peanut Allergy Using Continuous Likelihood Ratios, Nalin Ug May 2020

Diagnosis Of Peanut Allergy Using Continuous Likelihood Ratios, Nalin Ug

Research Days

No abstract provided.


Maternal Education And Cockroach Sensitization In Asthmatic Children, Jessica S. Van Mason, Ryan Allenbrand, David Williams, Kevin Kennedy, Salman Aljubran May 2020

Maternal Education And Cockroach Sensitization In Asthmatic Children, Jessica S. Van Mason, Ryan Allenbrand, David Williams, Kevin Kennedy, Salman Aljubran

Research Days

No abstract provided.


Novel Prenatal Diagnosis Of Protein C Deficiency And Primary Prophylaxis With Protein C Concentrate: A Case Series, Alexandra Prosser May 2020

Novel Prenatal Diagnosis Of Protein C Deficiency And Primary Prophylaxis With Protein C Concentrate: A Case Series, Alexandra Prosser

Research Days

No abstract provided.


Inpatient Management Of Hirschsprung’S Associated Enterocolitis (Haec) Treatment – The Benefits Of Standardized Care, Obiyo O. Osuchukwu May 2020

Inpatient Management Of Hirschsprung’S Associated Enterocolitis (Haec) Treatment – The Benefits Of Standardized Care, Obiyo O. Osuchukwu

Research Days

No abstract provided.


Laparoscopic Gastrostomy During An Open Abdominal Procedure, Charlene Dekonenko, Obiyo O. Osuchukwu May 2020

Laparoscopic Gastrostomy During An Open Abdominal Procedure, Charlene Dekonenko, Obiyo O. Osuchukwu

Research Days

No abstract provided.


Surgical Management Of Superior Mesenteric Artery Syndrome In Children, Charlene Dekonenko, Obiyo O. Osuchukwu May 2020

Surgical Management Of Superior Mesenteric Artery Syndrome In Children, Charlene Dekonenko, Obiyo O. Osuchukwu

Research Days

No abstract provided.


Institution Experience With Laparoscopic Hernia Repair In 500 Children, Obiyo O. Osuchukwu May 2020

Institution Experience With Laparoscopic Hernia Repair In 500 Children, Obiyo O. Osuchukwu

Research Days

No abstract provided.


Same-Day Discharge And Quality Of Life For Primary Laparoscopic Rectopexy For Rectal Prolapse In Children- A 10-Year Experience, Obiyo O. Osuchukwu May 2020

Same-Day Discharge And Quality Of Life For Primary Laparoscopic Rectopexy For Rectal Prolapse In Children- A 10-Year Experience, Obiyo O. Osuchukwu

Research Days

No abstract provided.


Same Day Discharge For Pediatric Laparoscopic Gastrostomy, Charlene Dekonenko, Obiyo O. Osuchukwu May 2020

Same Day Discharge For Pediatric Laparoscopic Gastrostomy, Charlene Dekonenko, Obiyo O. Osuchukwu

Research Days

No abstract provided.


Childhood Absence With Polyspike Ictal-Onset, Sherouk A. Abdelmoity May 2020

Childhood Absence With Polyspike Ictal-Onset, Sherouk A. Abdelmoity

Research Days

No abstract provided.


Estimation Of The Burden Of Out-Of-Hospital Traumatic Cardiac Arrest In Karachi, Pakistan, Using A Cross-Sectional Capture-Recapture Analysis, Minaz Mawani, Syed Iqbal Azam, Muhammad Masood Kadir, Zainab Samad, Junaid Abdul Razzak May 2020

Estimation Of The Burden Of Out-Of-Hospital Traumatic Cardiac Arrest In Karachi, Pakistan, Using A Cross-Sectional Capture-Recapture Analysis, Minaz Mawani, Syed Iqbal Azam, Muhammad Masood Kadir, Zainab Samad, Junaid Abdul Razzak

Community Health Sciences

Background: The burden of trauma-related-out-of-hospital cardiac arrest (OHCA) in developing countries like Pakistan remains largely unexplored due to a lack of organized pre-hospital systems. In order to estimate the burden, we used a two-sample capture-recapture method which has been used in several domains to estimate difficult-to-count populations.
Methods: We obtained 3-month data from two sources: Records of two major EMS (emergency medical services) systems and five major hospitals providing coverage to the city's population. All adults with traumatic OHCA were included. Information on variables such as name, age, gender, date and time of arrest, cause of arrest, and destination hospital …


Wound And Stoma Care Education For Primary Care Providers, Deanna Garza May 2020

Wound And Stoma Care Education For Primary Care Providers, Deanna Garza

Doctor of Nursing Practice (DNP) Projects

Abstract

Problem. Patients with percutaneous endoscopic gastrostomy (PEG) tubes and their families report physical and psychosocial changes associated with complications after gastrointestinal surgeries. They are at particular risk for tube dislodgement, leakage, infection, poor fit, and skin irritation. The lack of specialization and fundamental stoma care knowledge among community health care providers potentially results in unintended consequences, leaving the system inefficient with fundamental inequities of stoma care delivery. While there is an increasing amount of accessibility to specialty centers for other types of wound care, stoma care support resources are scarce and not readily available to patients.

Context: This Doctor …


Abstract 219: Use Of Machine Learning Models To Identify Atherosclerotic Cardiovascular Disease Patients At Very High Risk For Future Events In A Multi-State Health Care System, Hsin-Fang Li, Amir Ali, Kateri Spinelli, A Sajja, Ss Virani, Ss Martin, Tyler J Gluckman May 2020

Abstract 219: Use Of Machine Learning Models To Identify Atherosclerotic Cardiovascular Disease Patients At Very High Risk For Future Events In A Multi-State Health Care System, Hsin-Fang Li, Amir Ali, Kateri Spinelli, A Sajja, Ss Virani, Ss Martin, Tyler J Gluckman

Articles, Abstracts, and Reports

Background: In the 2018 AHA/ACC Blood Cholesterol Guideline, it is recommended that ASCVD patients be classified as very high-risk (VHR) vs not-VHR (NVHR) to guide treatment decisions. This has important implications for ezetimibe and PCSK9 inhibitor eligibility. We aimed to develop a tool that could assist in more easily identifying VHR patients based on machine learning (ML) techniques. This approach offers a powerful, assumption-free alternative to conventional methods, such as logistic regression, to identify potential interactions among risk factors while incorporating the hierarchy of interaction among variables.

Method: We used EHR-derived ICD-10 codes to identify patients within our health system …


Risk Factors For Postpartum Sepsis: A Nested Case-Control Study, Samina Bakhtawar, Sana Sheikh, Rahat Qureshi, Zahra Hoodbhoy, Beth Payne, Iqbal Azam Syed, Peter Von Dadelszen, Laura Magee May 2020

Risk Factors For Postpartum Sepsis: A Nested Case-Control Study, Samina Bakhtawar, Sana Sheikh, Rahat Qureshi, Zahra Hoodbhoy, Beth Payne, Iqbal Azam Syed, Peter Von Dadelszen, Laura Magee

Community Health Sciences

Background: The Majority (99%) of maternal deaths occur in low and middle-income countries. The three most important causes of maternal deaths in these regions are postpartum hemorrhage, pre-eclampsia and puerperal sepsis. There are several diagnostic criteria used to identify sepsis and one of the commonly used criteria is systematic inflammatory response syndrome (SIRS). However, these criteria require laboratory investigations that may not be feasible in resource-constrained settings. Therefore, this study aimed to develop a model based on risk factors and clinical signs and symptoms that can identify sepsis early among postpartum women.
Methods: A case-control study was nested in an …


Cirrhosis For The Pcp, Krys Foster, Md, Mph May 2020

Cirrhosis For The Pcp, Krys Foster, Md, Mph

Department of Family & Community Medicine Presentations and Grand Rounds

Objectives:

  • Understand the morbidity and mortality associated with Cirrhosis in the United States
  • Recognize etiologies and clinical presentation of cirrhosis
  • Identify decompensated cirrhosis and approaches to treatment and monitoring

Agenda

  • Definition and Epidemiology
  • Etiologies
  • Clinical Presentation
  • Diagnosis and Evaluation/Classification
  • Management of Compensated Cirrhosis
  • Decompensated Cirrhosis & Complications
  • ○ Portal Hypertension ○ Varices ○ Ascites ○ SBP ○ Hepatorenal Syndrome ○ Hepatic Encephalopathy
  • Secondary Prevention and Long Term Management
  • Conclusions


Vaccines, Children, And The Public Health Trust, Christopher Chambers, Md May 2020

Vaccines, Children, And The Public Health Trust, Christopher Chambers, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Objectives

  1. Review the impact of immunizations on the public health over the past 50 years.
  2. Childhood Vaccines Now
  3. Describe the challenges associated with trying to eliminate “immunizable” diseases. Examples: Invasive Pneumoccal Disease, Neisseria meningitis
  4. The Future