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2020

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Articles 2251 - 2280 of 4794

Full-Text Articles in Medical Specialties

The Anti-Epileptic Dilemma – A How To For Transitioning Patients On Seizure Medications To Hospice, Erin Kelly, Do, John Liantonio, Md, Mba, Hdmc, Debra Vermette, Md May 2020

The Anti-Epileptic Dilemma – A How To For Transitioning Patients On Seizure Medications To Hospice, Erin Kelly, Do, John Liantonio, Md, Mba, Hdmc, Debra Vermette, Md

Health Equity and Quality Improvement (HEQI) Summit

Objective

We propose an approach to antiepiletics in hospice that includes the evaluation of steroids, medication options, pharmacy consultation and seizure breakthrough plan so that we meet the goals of the patient on hospice.


To Anticoagulate Or Not: Decision Making Surrounding Anticoagulation In Patients In Hospice And Palliative Care Programs, Erin Kelly, Do, John Liantonio, Md, Mba, Hdmc, Debra Vermette, Md May 2020

To Anticoagulate Or Not: Decision Making Surrounding Anticoagulation In Patients In Hospice And Palliative Care Programs, Erin Kelly, Do, John Liantonio, Md, Mba, Hdmc, Debra Vermette, Md

Health Equity and Quality Improvement (HEQI) Summit

Objectives

  • Describe the current guidelines for CAT treatment. - Assess risk factors for bleeding and thrombosis in cancer patients and risk/benefits of anticoagulation.
  • Recognize the need for individualized anticoagulation plans in order to make informed decisions that may differ from the guidelines.
  • Propose anticoagulation in hospice if it will achieve the goals of the patient.


Standardized Bronchoscopy Testing For Immunocompromised Patients, C. Nieweld, A. Gandler, K. Biblowitz, B. Menachem, J. Most May 2020

Standardized Bronchoscopy Testing For Immunocompromised Patients, C. Nieweld, A. Gandler, K. Biblowitz, B. Menachem, J. Most

Health Equity and Quality Improvement (HEQI) Summit

Aims for Improvement

  • Determine the consistency in which the order set was followed
  • Determine the length of time from finding pulmonary infiltrate to consultation
  • Determine the length of time from consultation to bronchoscopy
  • Determine whether a follow up note was written by pulmonary
  • Determine whether management is affected based on obtained results


Improving Serial Imaging Protocols In Spontaneous Intracerebral Hemorrhage, Kevin Hines, Md, Nikolaos Mouchtouris, Md, Fadi Al-Saiegh, Md, Karim Hafazalla, Jacob Mazza, Giuliana Labella, Muhammad K. Athar, Md, Adam Flanders, Md, M. Reid Gooch, Md, Stavropoula Tjoumakaris, Md, Robert H. Rosenwasswer, Md, Pascal Jabbour, Md May 2020

Improving Serial Imaging Protocols In Spontaneous Intracerebral Hemorrhage, Kevin Hines, Md, Nikolaos Mouchtouris, Md, Fadi Al-Saiegh, Md, Karim Hafazalla, Jacob Mazza, Giuliana Labella, Muhammad K. Athar, Md, Adam Flanders, Md, M. Reid Gooch, Md, Stavropoula Tjoumakaris, Md, Robert H. Rosenwasswer, Md, Pascal Jabbour, Md

Health Equity and Quality Improvement (HEQI) Summit

Aims for Improvement

Aim to decrease unnecessary use of serial imaging in sICH patients.

  • This project plans to decrease the number of scans in this patient population while increasing faculty/staff satisfaction and efficiency of resource utilization.
  • The goal is to decrease HCT utilization by 20% without compromising patient care or decision making.
  • After finalizing and approving the HCT protocol, implementation of a trial period for two


Mitigation Of Ed Patient Boarding: Transferring Admissions From The Center City Ed To Methodist, Quinton Campbell, Md, Lauren Selame, Md, James Cirone, Do, Elizabeth Teixeira, Md, Jennifer White, Md, Frederick Randolph, Md May 2020

Mitigation Of Ed Patient Boarding: Transferring Admissions From The Center City Ed To Methodist, Quinton Campbell, Md, Lauren Selame, Md, James Cirone, Do, Elizabeth Teixeira, Md, Jennifer White, Md, Frederick Randolph, Md

Health Equity and Quality Improvement (HEQI) Summit

Objectives:

  • Objectively analyze transferred patient transfers cases as far as LOS (length of stay), final diagnosis, and transfer failure.
  • Assess patient satisfaction with the transfer process as means to identify areas for improvement as well as potential patient safety issues.


Time To Defibrillation After Onset Of Ventricular Fibrillation And Ventricular Tachycardia Cardiac Arrest At Thomas Jefferson University Hospital And Jefferson Hospital For Neurosciences., Sairamya Bodempudi, Md, Yair Lev, Md May 2020

Time To Defibrillation After Onset Of Ventricular Fibrillation And Ventricular Tachycardia Cardiac Arrest At Thomas Jefferson University Hospital And Jefferson Hospital For Neurosciences., Sairamya Bodempudi, Md, Yair Lev, Md

Health Equity and Quality Improvement (HEQI) Summit

Aims for Improvement

  • Improve average time to defibrillation after VFib/pVTach cardiac arrest to < 2 minutes within an 8 month interval at TJUH and JHN.
  • Improve the percent of VFib/pVTach cardiac arrests that are defibrillated within the recommended 2 minute interval by 30% at TJUH/JHN within an 8 month interval


Exploring The Effectiveness Of Asthma Action Plans In Long-Term Asthma Management, Pankhuri Jha, Jessica Most, Md May 2020

Exploring The Effectiveness Of Asthma Action Plans In Long-Term Asthma Management, Pankhuri Jha, Jessica Most, Md

Health Equity and Quality Improvement (HEQI) Summit

Aims for Improvement

  • Determine the efficacy of AAP in helping patients feel more confident in their self-management
  • Improve asthma control by at least 10% after receiving an Asthma Action Plan


Experience With A Comprehensive Multidisciplinary Geriatric Oncology Center, Michael Weissberger, Md, Ms, Emma De Louw, Md, Kristine Swartz, Md, Lauren Hersh, Md, Andrew Chapman, Do, Facp May 2020

Experience With A Comprehensive Multidisciplinary Geriatric Oncology Center, Michael Weissberger, Md, Ms, Emma De Louw, Md, Kristine Swartz, Md, Lauren Hersh, Md, Andrew Chapman, Do, Facp

Health Equity and Quality Improvement (HEQI) Summit

Research Goals

  1. 1. Describe the population seen in the SAOC over the past 6 years
  2. Remediate and complete the EPIC flowsheets
  3. Merge data with existing RedCAP data


Identifying Barriers To Statin Therapy In Diabetic Patients In A Large Ambulatory Practice, Jennifer Moyer, Md, Rachel Ehrman-Dupre, Md, Andrew Rabovsky, Md, Simon Newsom, Md, Pooja Padgaonkar, Md, Julita Mitchell, Md, Sarah Hirsh, Md, Madeline Taskier, Md, Robert Wiley, Md, Lilli Flink, Md, Greta Bires, Md, Geoffrey Mills, Md May 2020

Identifying Barriers To Statin Therapy In Diabetic Patients In A Large Ambulatory Practice, Jennifer Moyer, Md, Rachel Ehrman-Dupre, Md, Andrew Rabovsky, Md, Simon Newsom, Md, Pooja Padgaonkar, Md, Julita Mitchell, Md, Sarah Hirsh, Md, Madeline Taskier, Md, Robert Wiley, Md, Lilli Flink, Md, Greta Bires, Md, Geoffrey Mills, Md

Health Equity and Quality Improvement (HEQI) Summit

Aim 1: To understand the root cause(s) for gaps in statin therapy within a large ambulatory care practice.

Aim 2: To improve provider awareness of indications for statin therapy, as recommended by the ACC/AHA guidelines.

Aim 3: To increase the proportion of patients with diabetes at our practice that are on statin therapy.


Sglt2 Inhibitors In Patients With Diabetes And Cardiovascular Disease, Cristina Calogero, Md, Jillian Cooper, Md, Mathew Francis, Md, Joseph Grogg, Md, Shuwen Lin, Md, Patrick Prior, Md, Bo Hyung Yoon, Md, Yair Lev, Md May 2020

Sglt2 Inhibitors In Patients With Diabetes And Cardiovascular Disease, Cristina Calogero, Md, Jillian Cooper, Md, Mathew Francis, Md, Joseph Grogg, Md, Shuwen Lin, Md, Patrick Prior, Md, Bo Hyung Yoon, Md, Yair Lev, Md

Health Equity and Quality Improvement (HEQI) Summit

Problem Definition: Multiple studies (e.g. EMPA-REG, CANVAS) demonstrate that SGLT2 Inhibitors (Inh) improve cardiac outcomes in patients with Type II Diabetes (DM2) with comorbid Cardiovascular Disease (CVD) including Heart Failure and Coronary Artery Disease. SGLT2 Inhibitors are considered standard of care for patients with DM2 and CVD. Based on literature published in European Journal of Preventative Cardiology and JACC HF, our prediction is that physicians at Thomas Jefferson University Hospital Ambulatory Practices (TJUH) under-utilize SGLT2 Inh for patients with co-morbid CVD and DM2.

Aims for Improvement: Within the Jefferson Healthcare System, we sought to determine: Future Interventions

  1. The percentage of …


Prevalence Of Gastrointestinal Symptoms In Patients With Cannabis Abuse Presenting To The Emergency Room, Hadiatou Barry, Md, Mph, Botros Shenoda, Md, Phd, Msc, Purujit Thaker, Md, Mary Naglak, Phd May 2020

Prevalence Of Gastrointestinal Symptoms In Patients With Cannabis Abuse Presenting To The Emergency Room, Hadiatou Barry, Md, Mph, Botros Shenoda, Md, Phd, Msc, Purujit Thaker, Md, Mary Naglak, Phd

Health Equity and Quality Improvement (HEQI) Summit

Introduction: Cannabis is a common recreational drug among young adults that is used to induce euphoria, promote relaxation and enhance appetite. There is a recognized correlation between cannabis abuse and cyclic episodes of nausea, vomiting, and abdominal pain (cannabinoid hyperemesis syndrome). However, the contribution of such symptoms to emergency room visits and hospital admissions is not known.

Methods: A one-year, retrospective study was conducted on patients who presented to the emergency department and were later admitted at Abington Hospital-Jefferson Health with confirmed cannabis use (positive urine drug screen).

Aim/Goal: Our primary outcome was to understand the prevalence of gastrointestinal symptoms …


Use Of Epic Emr For Early Identification And Management Of Patients At Risk Of Cardiac Implantable Electronic Device (Cied) Infection, Priya Rajagopalan, Md, Yair Lev, Md, Arnold J. Greenspon, Md May 2020

Use Of Epic Emr For Early Identification And Management Of Patients At Risk Of Cardiac Implantable Electronic Device (Cied) Infection, Priya Rajagopalan, Md, Yair Lev, Md, Arnold J. Greenspon, Md

Health Equity and Quality Improvement (HEQI) Summit

Objectives

  • Aim of our project was early identification of 100% of patients with a CIED IMPLANT presenting with bacteremia
  • Process involves use of EPIC EMR to automatically identify patients with positive blood cultures
  • Traditionally, cardiologists are alerted by the care team using the CONSULT system for management of these patients
  • EPIC EMR as an adjunct to the CONSULT system


Improving Evaluation And Follow-Up Of Patients Diagnosed With Left Bundle Branch Block, Naman Upadhyay, Md, Alvin George, Md, John Schanz, Ms, Behzad Pavri, Md, Yair Lev, Md May 2020

Improving Evaluation And Follow-Up Of Patients Diagnosed With Left Bundle Branch Block, Naman Upadhyay, Md, Alvin George, Md, John Schanz, Ms, Behzad Pavri, Md, Yair Lev, Md

Health Equity and Quality Improvement (HEQI) Summit

Left bundle branch block (LBBB) is a pathologic finding on electrocardiogram (ECG).

  • Most commonly present in patients with antecedent hypertension, cardiac enlargement, coronary artery disease or a combination of these
  • Class 1B recommendation: Those with findings of LBBB on ECG should undergo transthoracic echocardiography for evaluation of underlying heart disease
  • LBBB is prevalent (33%) in patients with heart failure
  • Cardiac resynchronization therapy can improve left ventricular mechanical function in patients with LBBB (QRS >150 msec)

This study aims to understand how effectively we are evaluating and following up these patients at Thomas Jefferson University Hospital.


The Echo Of An Unanswered Ring: Improving The Rate Of Reporting Abnormal Findings On Echocardiography At Tjuh, Tanuka Datta, Md, Bharaniabirami Rajaram, Md, Alvin George, Md, Madeleine Norris, Yair Lev, Md May 2020

The Echo Of An Unanswered Ring: Improving The Rate Of Reporting Abnormal Findings On Echocardiography At Tjuh, Tanuka Datta, Md, Bharaniabirami Rajaram, Md, Alvin George, Md, Madeleine Norris, Yair Lev, Md

Health Equity and Quality Improvement (HEQI) Summit

Aim: To improve the rate of reporting abnormal echo findings verbally to primary patient care teams.

Goal: Increase the rate of attending reported abnormal echo findings to a patient's primary team by 75% in 6 months.


Does Discharge Pharmacy Affect Outcomes After Percutaneous Coronary Intervention?, Patrick Prior, Md, Lisa Moss, Abhinav Nair, Md, Preya Simlote, Md, David Fischman, Md May 2020

Does Discharge Pharmacy Affect Outcomes After Percutaneous Coronary Intervention?, Patrick Prior, Md, Lisa Moss, Abhinav Nair, Md, Preya Simlote, Md, David Fischman, Md

Health Equity and Quality Improvement (HEQI) Summit

Aims for Improvement

To reduce the rate of this institution’s readmission rate in patients discharged after PCI, by identifying the current trends in readmission in relation to prescription and medication delivery practices over the past 1 year.


Optimizing Evaluation And Treatment Of Patients With Nausea And Vomiting Of Pregnancy In The Emergency Department, Danielle N. Carr, Md, Angela Carracino, Do, Alisha Sangal, Md, Madeline Smith, Md May 2020

Optimizing Evaluation And Treatment Of Patients With Nausea And Vomiting Of Pregnancy In The Emergency Department, Danielle N. Carr, Md, Angela Carracino, Do, Alisha Sangal, Md, Madeline Smith, Md

Health Equity and Quality Improvement (HEQI) Summit

Problem Definition

  • Nausea and vomiting of pregnancy (NVP). Approximately 50% prevalence rate
  • Pregnant patients with NVP require special considerations for treatment
  • Long ER wait times
  • Possibly avoidable hospital admissions


Improving Blood Pressure Control Through Blood Pressure Measurement In An Ambulatory Urban Family Medicine Clinic, Sara Ancona, Md, Zachary Klock, Md, Aimee Mcmullin, Md, Zeynep Uzumcu, Md, Olivia Seecof, Md, Graham Stratton, Md, Alexa Waters, Md, Caitlyn Haines, Md, Brittany Hozick, Md, Jose Medina, Md, Geoffrey Mills, Md, Phd May 2020

Improving Blood Pressure Control Through Blood Pressure Measurement In An Ambulatory Urban Family Medicine Clinic, Sara Ancona, Md, Zachary Klock, Md, Aimee Mcmullin, Md, Zeynep Uzumcu, Md, Olivia Seecof, Md, Graham Stratton, Md, Alexa Waters, Md, Caitlyn Haines, Md, Brittany Hozick, Md, Jose Medina, Md, Geoffrey Mills, Md, Phd

Health Equity and Quality Improvement (HEQI) Summit

Aim Statement: To increase the percentage of patients over the age of 18 with BP controlled to a goal of <140/90 from a baseline of 58% to 68% by April 2020.


Changing Internal Medicine Residents’ Perspective On Social Determinants Of Health, Daniel Tran, Do, Hiba Ansari, Do, Layla Barrera, Do, Magdala Chery, Do May 2020

Changing Internal Medicine Residents’ Perspective On Social Determinants Of Health, Daniel Tran, Do, Hiba Ansari, Do, Layla Barrera, Do, Magdala Chery, Do

Health Equity and Quality Improvement (HEQI) Summit

Background: Social determinants of health (SDOH) shape the conditions of a person’s daily life and include factors such as housing, occupation, education, safety and income. While physicians are aware of the inequalities that exists in healthcare, not all physicians feel adequately able to address such concerns. Understanding of factors that contribute to the development and perpetuation of inequities in health care must be developed at the medical education training level.

Objectives: Evaluate internal medicine residents’ understanding of SDOH and implement a curriculum on health disparities in order to improve their comfort in addressing social needs.

Methods: A survey regarding several …


Urine Drug Screening At The Sleep Disorder Center, Rohin Saroya, Md, Karl Doghramji, Md May 2020

Urine Drug Screening At The Sleep Disorder Center, Rohin Saroya, Md, Karl Doghramji, Md

Health Equity and Quality Improvement (HEQI) Summit

Aim

  • Introduce UDS for all patients undergoing MSLT or MWT
  • Eliminate false positive and negative results
  • Optimize management of disorder

Goal

  • To have 100% of patients undergoing an MSLT or MWT to have a UDS


Assessing Internal Medicine Resident Comfort With Obtaining Consent For Autopsies, Zach French, Kelly Hughes, Edward Wang, Elizabeth Braden May 2020

Assessing Internal Medicine Resident Comfort With Obtaining Consent For Autopsies, Zach French, Kelly Hughes, Edward Wang, Elizabeth Braden

Health Equity and Quality Improvement (HEQI) Summit

Objective

We aim to increase resident comfort and knowledge of the autopsy process by 20% based on average survey response scores


Detection Of Coronary Artery Disease On Ct Chest Imaging, K. Mirzozoda, Md, Mba, J. Vojnika, Md, R. Mohammed, Md, H. Landon, Md, C. Murphy, Md, Y. Lev, Md May 2020

Detection Of Coronary Artery Disease On Ct Chest Imaging, K. Mirzozoda, Md, Mba, J. Vojnika, Md, R. Mohammed, Md, H. Landon, Md, C. Murphy, Md, Y. Lev, Md

Health Equity and Quality Improvement (HEQI) Summit

Overall aim: Improve diagnosis and management of CAD based on CT chest imaging.

  • Improve diagnosis of silent CAD based on CT chest imaging: more patients who have findings of CAC on CT chest imaging will be diagnosed with CAD.
  • Increase the number of appropriate statin prescriptions based on CAD findings on CT chest imaging.


Time Value Analysis Of Inpatient Endoscopy Workflow, Sanaa Arastu, Md, Andrew Elden, Md, Raymond Janowski, Md, Aaron Martin, Md, Joseph Yoo, Md, Richard Denicola, Md, Amy Javia, Md, Melissa Vitolo, Md, Linda Yan, Md, Christopher Cao, Md, Scott Manski, Md, Christopher Schmoyer, Md, Brianna Shinn, Md, Mitchell Conn, Md May 2020

Time Value Analysis Of Inpatient Endoscopy Workflow, Sanaa Arastu, Md, Andrew Elden, Md, Raymond Janowski, Md, Aaron Martin, Md, Joseph Yoo, Md, Richard Denicola, Md, Amy Javia, Md, Melissa Vitolo, Md, Linda Yan, Md, Christopher Cao, Md, Scott Manski, Md, Christopher Schmoyer, Md, Brianna Shinn, Md, Mitchell Conn, Md

Health Equity and Quality Improvement (HEQI) Summit

Aims for Improvement

  • Our aim was to evaluate the variables involved in room turnover and identify any delays that lead to the time difference found between inpatient and outpatient rooms.
  • We planned to design an intervention to improve efficiency in the endoscopy suite and complete more inpatient cases.
  • We predicted that completion of more inpatient cases would subsequently decrease the need for cancellation and rescheduling of medically necessary cases on a daily basis.


Mild Traumatic Brain Injury: Parental Education For An Active Child, Elizabeth W. Roth May 2020

Mild Traumatic Brain Injury: Parental Education For An Active Child, Elizabeth W. Roth

Theses and Graduate Projects

Mild traumatic brain injuries in the pediatric population are prevalent and pervasive. Identification and recognition of concussion symptoms is complicated by variable symptom manifestation and duration. The purpose of this evidence-based DNP project was to implement a concussion education intervention to increase parental recognition and knowledge regarding pediatric concussions. Individualized, in-person education, evidence-based injury prevention, symptom recognition, and collaboration encouraged lifestyle modification to reduce childhood injuries. Evaluation of parental concerns concluded a desire for future health promotion education resulting in bimonthly meetings to further improve personal, familial, and professional health.


A Web-Based, Positive Emotion Skills Intervention For Enhancing Posttreatment Psychological Well-Being In Young Adult Cancer Survivors (Empower): Protocol For A Single-Arm Feasibility Trial, John M. Salsman, Laurie E. Mclouth, Michael Cohn, Janet A. Tooze, Mia Sorkin, Judith T. Moskowitz May 2020

A Web-Based, Positive Emotion Skills Intervention For Enhancing Posttreatment Psychological Well-Being In Young Adult Cancer Survivors (Empower): Protocol For A Single-Arm Feasibility Trial, John M. Salsman, Laurie E. Mclouth, Michael Cohn, Janet A. Tooze, Mia Sorkin, Judith T. Moskowitz

Behavioral Science Faculty Publications

BACKGROUND: Adolescent and young adult cancer survivors (AYAs) experience clinically significant distress and have limited access to supportive care services. Interventions to enhance psychological well-being have improved positive affect and reduced depression in clinical and healthy populations but have not been routinely tested in AYAs.

OBJECTIVE: The aim of this protocol is to (1) test the feasibility and acceptability of a Web-based positive emotion skills intervention for posttreatment AYAs called Enhancing Management of Psychological Outcomes With Emotion Regulation (EMPOWER) and (2) examine proof of concept for reducing psychological distress and enhancing psychological well-being.

METHODS: The intervention development and testing are …


An Osteocalcin-Deficient Mouse Strain Without Endocrine Abnormalities, Cassandra R. Diegel, Steven Hann, Ugar M. Ayturk, Jennifer C. W. Hu, Kyungeun Lim, Casey J. Droscha, Zachary B. Madaj, Gabrielle E. Foxa, Isaac Izaguirre, Vai Vivarium And Transgenics Core, Noorulain Paracha, Bohdan Pidhaynyy, Terry L. Dowd, Alexandra G. Robling, Matthew L. Warman, Bart O. Williams May 2020

An Osteocalcin-Deficient Mouse Strain Without Endocrine Abnormalities, Cassandra R. Diegel, Steven Hann, Ugar M. Ayturk, Jennifer C. W. Hu, Kyungeun Lim, Casey J. Droscha, Zachary B. Madaj, Gabrielle E. Foxa, Isaac Izaguirre, Vai Vivarium And Transgenics Core, Noorulain Paracha, Bohdan Pidhaynyy, Terry L. Dowd, Alexandra G. Robling, Matthew L. Warman, Bart O. Williams

Publications and Research

Osteocalcin (OCN), the most abundant noncollagenous protein in the bone matrix, is reported to be a bone-derived endocrine hormone with wide-ranging effects on many aspects of physiology, including glucose metabolism and male fertility. Many of these observations were made using an OCN-deficient mouse allele (Osc– ) in which the 2 OCN-encoding genes in mice, Bglap and Bglap2, were deleted in ES cells by homologous recombination. Here we describe mice with a new Bglap and Bglap2 double-knockout (dko) allele (Bglap/2p.Pro25fs17Ter) that was generated by CRISPR/Cas9-mediated gene editing. Mice homozygous for this new allele do not express full-length Bglap or Bglap2 mRNA …


Long-Term Patient-Reported Outcome Measures After Injury: National Trauma Research Action Plan (Ntrap) Scoping Review Protocol, Juan Pablo Herrera-Escobar, Manuel A. Castillo-Angeles, Samia Y. Osman, Claudia P. Orlas, Mahin B. Janjua, Muhammad Abdullah Arain, Emma Reidy, Molly P. Jarman, Michelle A. Price, Adil H. Haider May 2020

Long-Term Patient-Reported Outcome Measures After Injury: National Trauma Research Action Plan (Ntrap) Scoping Review Protocol, Juan Pablo Herrera-Escobar, Manuel A. Castillo-Angeles, Samia Y. Osman, Claudia P. Orlas, Mahin B. Janjua, Muhammad Abdullah Arain, Emma Reidy, Molly P. Jarman, Michelle A. Price, Adil H. Haider

Medical College Documents

Background: A significant proportion of patients who survive traumatic injury continue to suffer impaired functional status and increased mortality long after discharge. However, despite the need to improve long-term outcomes, trauma registries in the USA do not collect data on outcomes or care processes after discharge. One of the main barriers is the lack of consensus regarding the optimal outcome metrics.
Objectives: To describe the methodology of a scoping review evaluating current evidence on the available measures for tracking functional and patient-reported outcomes after injury. The aim of the review was to identify and summarize measures that are being used …


Assisting Children With Velocardiofacial Syndrome Who Have Developmental Disabilities And Delays Associated With Speech, Communication, And Education, Mckenzie K. Holty May 2020

Assisting Children With Velocardiofacial Syndrome Who Have Developmental Disabilities And Delays Associated With Speech, Communication, And Education, Mckenzie K. Holty

Honors Thesis

Children with velocardiofacial syndrome (VCFS) have a variety of complex needs. Research shows that VCFS is characterized by a combination of medical problems, developmental delays, and learning disabilities, which vary from child to child. This syndrome also puts adolescents at a higher risk for developing psychiatric and psychotic disorders. The complexity of symptoms that can arise from VCFS can influence the ability of these children to communicate, socialize, and learn effectively. This literature review aims to discuss literature for caregivers, educators, and physicians to aid children effectively and understand their challenges relating to speech, communication, and education. This topic is …


Effectiveness And Safety Of Oral Anticoagulants Among Nvaf Patients With Obesity: Insights From The Aristophanes Study, Steve Deitelzweig, Allison Keshishian, Amiee Kang, Amol Dhamane, Xuemei Luo, Xiaoyan Li, Neeraja Balachander, Lisa Rosenblatt, Jack Mardekian, Xianying Pan, Manuela Di Fusco, Alessandra B. Garcia Reeves, Huseyin Yuce, Gregory Y. H. Lip May 2020

Effectiveness And Safety Of Oral Anticoagulants Among Nvaf Patients With Obesity: Insights From The Aristophanes Study, Steve Deitelzweig, Allison Keshishian, Amiee Kang, Amol Dhamane, Xuemei Luo, Xiaoyan Li, Neeraja Balachander, Lisa Rosenblatt, Jack Mardekian, Xianying Pan, Manuela Di Fusco, Alessandra B. Garcia Reeves, Huseyin Yuce, Gregory Y. H. Lip

Publications and Research

This ARISTOPHANES analysis examined stroke/systemic embolism (SE) and major bleeding (MB) among a subgroup of nonvalvular atrial fibrillation (NVAF) patients with obesity prescribed warfarin or non-vitamin K antagonist oral anticoagulants (NOACs) in order to inform clinical decision making. A retrospective observational study was conducted among NVAF patients who were obese and initiated apixaban, dabigatran, rivaroxaban, or warfarin from 1 January 2013–30 September 2015, with data pooled from CMS Medicare and four US commercial claims databases. Propensity score matching was completed between NOACs and against warfarin in each database, and the results were pooled. Cox models were used to evaluate the …


A Fatal Case Of Primary Amoebic Meningoencephalitis From Recreational Waters., Edward Hamaty, Saif Faiek, Minesh Nandi, David Stidd, Manish Trivedi, Hari Kandukuri May 2020

A Fatal Case Of Primary Amoebic Meningoencephalitis From Recreational Waters., Edward Hamaty, Saif Faiek, Minesh Nandi, David Stidd, Manish Trivedi, Hari Kandukuri

Department of Neurosurgery Faculty Papers

Background: Naegleria Fowleri is a single-cell, thermophilic amphizoid amoeba, and a rare known causative agent for primary amoebic meningoencephalitis with >97% mortality rate. The amoeba resides in freshwater lakes and ponds but can also survive in inadequately chlorinated pools and recreational waters. The mode of infection includes activities such as diving or jumping into freshwater or submerging the head under the water. Although most commonly seen in the southern United States, it is essential to keep this clinical suspicion in mind regardless of geography, as presenting symptoms can be very similar to classic bacterial meningitis.

Conclusion: As per the CDC, …


A Rare Case Report And Literature Review Of Anabolic-Androgenic Steroids (Aas)-Induced Acute Myocardial Infarction, Qian Zhang, Khine S. Shan, Ahmad Raza, Neelima Manda, Travis Nace May 2020

A Rare Case Report And Literature Review Of Anabolic-Androgenic Steroids (Aas)-Induced Acute Myocardial Infarction, Qian Zhang, Khine S. Shan, Ahmad Raza, Neelima Manda, Travis Nace

Abington Jefferson Health Papers

Anabolic-androgenic steroids (AAS) are synthetic drugs manufactured to mimic the male sex hormone testosterone [1]. They are usually prescribed for medical conditions including but not limited to impotence in males, endometriosis, hypogonadism, and aplastic anemia [2]. It has also been used historically by athletes and bodybuilders to enhance performance as it can stimulate protein synthesis leading to an increase in muscle size and strength [3]. However, the use of AAS has become a serious global public health dilemma as it has been used widely by the general population to improve physical strength and appearance [1]. In …