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Medical Specialties Commons

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2019

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Articles 541 - 570 of 3514

Full-Text Articles in Medical Specialties

Preimplantation Genetic Testing (Pgt) And Frozen Embryo Transfer (Fet) Synergistically Decrease Pre-Term Delivery In Patients Undergoing In Vitro Fertilization (Ivf), Luke Ying Md, Mark Sanchez Md, James Baron Md, Ying Ying Oct 2019

Preimplantation Genetic Testing (Pgt) And Frozen Embryo Transfer (Fet) Synergistically Decrease Pre-Term Delivery In Patients Undergoing In Vitro Fertilization (Ivf), Luke Ying Md, Mark Sanchez Md, James Baron Md, Ying Ying

OB-GYN

OBJECTIVE: To study the effects of FET and FET post PGT (FET/PGT) on pre-term and very pre-term deliveries in patients undergoing IVF with elective single embryo transfer (eSET).

DESIGN: Retrospective cohort Society for Assisted Reproductive Technology (SART) data study.

MATERIALS AND METHODS: A retrospective cohort study was conducted using the publicly available data in the SART National Summary Report from 2014 to 2017. Cycle inclusion criteria were eSET, fresh embryo transfers (ET), and frozen embryo transfers (FET) with or without PGT (FET/PGT). Exclusion criteria were use of gestational carriers and donor eggs. Pregnancy outcomes included live births and gestational age …


Choking On Adenocarcinoma, Andre Sahakian Md, Rajesh Gulati Md Oct 2019

Choking On Adenocarcinoma, Andre Sahakian Md, Rajesh Gulati Md

Internal Medicine

No abstract provided.


So Much Soma, Satvir Dhillon Md, Gregory Shimizu Md Oct 2019

So Much Soma, Satvir Dhillon Md, Gregory Shimizu Md

Internal Medicine

No abstract provided.


Moyamoya Disease Presenting With Stroke, Timothy Collins, Chimezie Ubbaonu, Phuong Vo Oct 2019

Moyamoya Disease Presenting With Stroke, Timothy Collins, Chimezie Ubbaonu, Phuong Vo

Internal Medicine

No abstract provided.


Mindfulness Based Stress Reduction Increases Pathology Resident Self Wellness, Kaitlin Collura, Md, Phd, Joanna Chan, Md Oct 2019

Mindfulness Based Stress Reduction Increases Pathology Resident Self Wellness, Kaitlin Collura, Md, Phd, Joanna Chan, Md

Department of Pathology, Anatomy, and Cell Biology Posters

Stress during medical residency is a common, complex issue influenced by time demands, level of social support, and environmental factors. Increased stress levels can lead to resident burnout, and may contribute to the high rates of depression and suicide seen among physicians. In 2015, the ACGME began a campaign to promote resident wellness by calling on programs to implement strategies to develop resiliency, identify problems, and promote wellbeing. Mindfulness based stress reduction (MBSR) strategies have been shown to decrease burnout, improve mood, and increase compassion in healthcare providers. We implemented a wellness retreat to educate residents on the principles of …


Wellness Initiative Program And Effect On Pathology Resident Burnout Rate, Kaitlin Collura, Md, Phd, Michelle Nagurney, Md, Joanna Chan, Md Oct 2019

Wellness Initiative Program And Effect On Pathology Resident Burnout Rate, Kaitlin Collura, Md, Phd, Michelle Nagurney, Md, Joanna Chan, Md

Department of Pathology, Anatomy, and Cell Biology Posters

Increasing rates of physician burnout are reported across many medical specialties, including Pathology. In 2014, 52.5% of pathologists experienced symptoms of burnout compared to 37.6% in 2011. Suicide and depression rates in physicians are also higher than the average population. As a result, the ACGME began a campaign, in 2015, to foster resident wellness. The campaign calls for strategies to develop resiliency, identify problems, and promote well-being. While wellness initiatives may not change underlying mental illness, they may mitigate environmental factors that can exacerbate mental illness or suicidal behavior. Here we report results from a recently implemented resident wellness initiative …


Chemical Structure Of Fe–Ni Nanoparticles For Efficient Oxygen Evolution Reaction Electrocatalysis, Prashant Acharya, Zachary J. Nelson, Mourad Benamara, Ryan H. Manso, Sergio I. Perez Bakovic, Mojtaba Abolhassani, Sungsik Lee, Benjamin Reinhart, Jingyi Chen, Lauren F. Greenlee Oct 2019

Chemical Structure Of Fe–Ni Nanoparticles For Efficient Oxygen Evolution Reaction Electrocatalysis, Prashant Acharya, Zachary J. Nelson, Mourad Benamara, Ryan H. Manso, Sergio I. Perez Bakovic, Mojtaba Abolhassani, Sungsik Lee, Benjamin Reinhart, Jingyi Chen, Lauren F. Greenlee

Chemical Engineering Faculty Publications and Presentations

Bimetallic iron–nickel-based nanocatalysts are perhaps the most active for the oxygen evolution reaction (OER) in alkaline electrolytes. Recent developments in literature have suggested that the ratio of iron and nickel in Fe–Ni thin films plays an essential role in the performance and stability of the catalysts. In this work, the metallic ratio of iron to nickel was tested in alloy bimetallic nanoparticles. Similar to thin films, nanoparticles with iron–nickel atomic compositions where the atomic iron percentage is ≤50% outperformed nanoparticles with iron–nickel ratios of >50%. Nanoparticles of Fe20Ni80, Fe50Ni50, and Fe80Ni20 compositions were evaluated and demonstrated to have overpotentials of …


Targeted Epidural Blood Patches Under Fluoroscopic Guidance For Incidental Durotomies Related To Spine Surgeries: A Case Series., Andrew K. Wong, Mohammad Rasouli, Andrew Ng, Dajie Wang Oct 2019

Targeted Epidural Blood Patches Under Fluoroscopic Guidance For Incidental Durotomies Related To Spine Surgeries: A Case Series., Andrew K. Wong, Mohammad Rasouli, Andrew Ng, Dajie Wang

Department of Anesthesiology Faculty Papers

Introduction: Incidental durotomies are usually managed conservatively. However, 1.8% of patients require surgical dural repair for CSF leak. There are limited data available regarding the use of epidural blood patches (EBP) for persistent CSF leaks secondary to incidental durotomies. This case series aims to evaluate the efficacy of targeted EBPs under fluoroscopic guidance in the treatment of incidental durotomies.

Methods: Four patients with incidental durotomies after spine surgeries (one cervical decompression, one revision of L5-S1 decompression and fusion, and two lumbar decompressions) were included in this series. These patients did not respond to conservative management and subsequently underwent EBPs. Magnetic …


Effects Of Anaerobic Fatigue On The Tuck Jump Assessment Performance In Female Collegiate Club Athletes, Madison M. Vomacka, Nicole Bascelli, Monica Lininger Oct 2019

Effects Of Anaerobic Fatigue On The Tuck Jump Assessment Performance In Female Collegiate Club Athletes, Madison M. Vomacka, Nicole Bascelli, Monica Lininger

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: To determine the impact of a fatigue trial on the scores and number of jumps in a Tuck Jump Assessment (TJA) in female collegiate club athletes. The TJA is a 10-second plyometric jumping assessment used to replicate sport and identify lower extremity landing patterns. Scores from the TJA are summed together and those who score a 6 or higher are suggested for intervention training. Methods: Sixteen female club athletes (age: 20.9+1.9 years, weight: 59.13+7.72kg, height: 64.56+2.63cm) completed the TJA twice, once before performing a Wingate protocol and then again after. A dependent sample t-test was performed to determine any …


Prediction Modeling For Board Of Certification Exam Success For A Professional Master’S Athletic Training Program, Scott L. Bruce, Elizabeth K. Crawford, Gary B. Wilkerson, R. Barry Dale, Martina Harris, David W. Rausch Oct 2019

Prediction Modeling For Board Of Certification Exam Success For A Professional Master’S Athletic Training Program, Scott L. Bruce, Elizabeth K. Crawford, Gary B. Wilkerson, R. Barry Dale, Martina Harris, David W. Rausch

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Introduction: The Commission on Accreditation of Athletic Training Education mandates accredited athletic training programs have a minimum, three-year aggregate, first-attempt pass rate on the Board of Certification (BOC) examination of 70%. No studies have examined first-attempt BOC exam success for students enrolled in a professional master’s athletic training program (PMATP). Purpose: The purpose of this study was to identify factors associated with first-attempt success on the BOC examination for PMATP students. Methods: This cohort designed study used common application data from subjects’ university and PMATP applications to create prediction models to identify those factors that predict first-attempt success on the …


Performance Motion Analysis Unable To Predict Running-Related Injury In Collegiate Distance Runners, Christopher P. Melgares, Andrew C. Fry, Zachary Sanchez Oct 2019

Performance Motion Analysis Unable To Predict Running-Related Injury In Collegiate Distance Runners, Christopher P. Melgares, Andrew C. Fry, Zachary Sanchez

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

ABSTRACT

Purpose: Running-related injury (RRI) is common among competitive collegiate distance runners who participate in the sport of cross country and long distance track and field. Many factors contribute to RRI. Therefore, the purpose of this study was to determine if a 3D motion capture system’s performance motion analysis (PMA) report is capable of identifying factors predictive of RRI among collegiate distance runners during a cross country season. Methods: Thirty-one collegiate cross country runners (17 male, 14 female, mean age = 20.5 ± 1.4 years) gave their consent to participate in the investigation. Subjects were screened in the motion capture …


Comparison Of Pitching From Flat Ground Vs. 10-Inch Mound Regarding Elbow Varus Torque And Arm Speed, Stephen A. Cage, X. Neil Dong, Brandon J. Warner, Diana M. Gallegos Oct 2019

Comparison Of Pitching From Flat Ground Vs. 10-Inch Mound Regarding Elbow Varus Torque And Arm Speed, Stephen A. Cage, X. Neil Dong, Brandon J. Warner, Diana M. Gallegos

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: The purpose of this study was to examine the effect of throwing surface and distance on varus elbow torque and arm speed. Methods: 11 male collegiate baseball pitchers (age = 20.73 ± 1.56 years, height = 175.26 ± 9.03 cm, mass = 70.31 ± 9.03 kg) participated in this study. Varus elbow torque and distance were measured using a 3D motion sensor housed in a spandex sleeve at the medial joint line of the elbow. Participants were instructed to complete their normal warmup routine as if they were about to pitch in a bullpen session or a game. Participants …


An Examination Of Step Frequency And The Running Readiness Scale As Predictors Of Running-Related Injury In Collegiate Cross-Country Athletes, Shelley S. Payne Dr., Jenna D'Errico, D. S. Blaise Williams Oct 2019

An Examination Of Step Frequency And The Running Readiness Scale As Predictors Of Running-Related Injury In Collegiate Cross-Country Athletes, Shelley S. Payne Dr., Jenna D'Errico, D. S. Blaise Williams

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: The purpose of this study was to determine the relationship between step frequency and the Running Readiness Scale and the occurrence of a Running-Related Injury (RRI) in a Division III cross-country team. Methods: Each athlete was screened prior to the season for their step frequency at a preferred and pre-determined pace. Additionally, each athlete performed 6 musculoskeletal tests known as the “Running Readiness Scale” to assess body alignment, weight distribution, and muscular endurance. Each subject logged their training and competition schedule and injury history throughout the season using the Otterbein Run Tracker app. Results: Sixteen subjects completed data collection …


The Admissions Criteria For Professional Athletic Training Programs: A 2018 Review Of Post-Baccalaureate Degrees, Heidi L. Peters, Elizabeth R. Neil, Zachary K. Winkelmann, Lindsey E. Eberman Oct 2019

The Admissions Criteria For Professional Athletic Training Programs: A 2018 Review Of Post-Baccalaureate Degrees, Heidi L. Peters, Elizabeth R. Neil, Zachary K. Winkelmann, Lindsey E. Eberman

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: Athletic training education has advanced its professional degree to an entry level masters, a decision motivated by professional health education developments over the last 10 years. In respect to Commission on Accreditation of Athletic Training Education (CAATE) accreditation standards as well as evolutionary changes in athletic training education, current prerequisite expectations of entry level applicants are largely dependent upon program. Analysis of the publicly available documents via websites and other programmatic documents of professional athletic training including prerequisite classes, supplemental admissions requirements, length and credits of program, cost of attendance and degree level of core faculty. Methods: 144 professional …


Health Behaviors Of Athletic Trainers, Zachary K. Winkelmann, Maura E. Shea, Kelcey C. Granger, Lindsey E. Eberman, Kenneth E. Games Oct 2019

Health Behaviors Of Athletic Trainers, Zachary K. Winkelmann, Maura E. Shea, Kelcey C. Granger, Lindsey E. Eberman, Kenneth E. Games

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: Health behaviors, such as diet, tobacco, and physical activity, may serve to prevent disease and promote wellness throughout the population including athletic trainers (AT). Good health behaviors act as disease prevention measures to decrease prevalence of pathologies. Hours of sleep, substance use, nutritional intake, and physical activity are behaviors that may impact the health of athletic trainers (AT). The objective of the study was to describe health behaviors of ATs in comparison to the general population and recommended behaviors. Methods: We used a cross-sectional, web-based survey of clinically practicing ATs recruited from the National Athletic Trainers’ Association member database. …


Determining The Effectiveness Of Core Strengthening Exercise Therapies In Treating Nonspecific Low Back Pain: A Critically Appraised Topic, Amanda King, Andrea Cripps Oct 2019

Determining The Effectiveness Of Core Strengthening Exercise Therapies In Treating Nonspecific Low Back Pain: A Critically Appraised Topic, Amanda King, Andrea Cripps

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

CLINICAL SCENARIO: Nonspecific low back pain is a condition which impacts athletes of all calibers and sports. It has been found that a total of 68% of top athletes from multiple sports have been affected by nonspecific low back pain at some point in their career. Clinicians have discussed that tight hamstrings and weak core muscles are a major cause of nonspecific low back pain. A myriad of program exist to reduce nonspecific low back pain caused from hamstring tightness, however a standardized rehabilitation protocol for strengthening the core muscles to reduce nonspecific low back pain is not as well …


Aap To Honor Dr. Jackson With Lifetime Achievement Award, Children's Mercy Hospital Oct 2019

Aap To Honor Dr. Jackson With Lifetime Achievement Award, Children's Mercy Hospital

Our Story Continues

Mary Anne Jackson, MD, FAAP, FPIDS, FIDSA, is a rarity among physicians. Her curriculum vitae reads like a virtual “Who’s Who” in pediatric infectious diseases. She’s served as an associate editor of the American Academy of Pediatrics’ Red Book, a musthave reference for pediatricians across the nation.

Plus, she’s recently added the title of Interim Dean, University of Missouri-Kansas City School of Medicine, to her long list of accomplishments. She is also a Professor of Pediatrics and Pediatric Infectious Diseases specialist at Children’s Mercy Kansas City.

The AAP Section on Infectious Diseases will present Dr. Mary Anne Jackson with a …


Dose Effects Of Recombinant Adenovirus Immunization In Rodents, Eric A. Weaver Oct 2019

Dose Effects Of Recombinant Adenovirus Immunization In Rodents, Eric A. Weaver

Nebraska Center for Virology: Faculty Publications

Recombinant adenovirus type 5 (rAd) has been used as a vaccine platform against many infectious diseases and has been shown to be an effective vaccine vector. The dose of the vaccine varies significantly from study to study, making it very diffcult to compare immune responses and vaccine effcacy. This study determined the immune correlates induced by serial dilutions of rAd vaccines delivered intramuscularly (IM) and intranasally (IN) to mice and rats. When immunized IM, mice had substantially higher antibody responses at the higher vaccine doses, whereas, the IN immunized mice showed a lower response to the higher rAd vaccine doses. …


Twitter And Academic Urology In The United States And Canada: A Comprehensive Assessment Of The Twitter-Verse In 2019., Thenappan Chandrasekar, Hanan Goldberg, Zachary Klaassen, Christopher J. Wallis, Joon Yau Leong, Spencer Liem, Seth Teplitsky, Rodrigo Noorani, Stacy Loeb Oct 2019

Twitter And Academic Urology In The United States And Canada: A Comprehensive Assessment Of The Twitter-Verse In 2019., Thenappan Chandrasekar, Hanan Goldberg, Zachary Klaassen, Christopher J. Wallis, Joon Yau Leong, Spencer Liem, Seth Teplitsky, Rodrigo Noorani, Stacy Loeb

Department of Urology Faculty Papers

OBJECTIVE: To provide the first comprehensive analysis of the Twitter-verse amongst academic urologists and programs in North America.

METHODS: Using national accreditation and individual program websites, all active urology residency programs (USA & Canada) and academic Urology faculty at these programs were identified. Demographic data for each program (AUA section, resident class size) and physician (title, fellowship training, Scopus H-index and citations) were documented. Twitter metrics (Twitter handle, date joined, # tweets, # followers, # following, likes) for programs and physicians were catalogued (data capture: March-April 2019). Descriptive analyses and temporal trends in Twitter utilization amongst programs and physician were …


Fetal Myocardial Performance Index In The Third Trimester Of Pregnancy: Feasibility And Reproducibility Of Conventional Spectral Doppler Versus Spectral Tissue Doppler Technique, Lea M. Porche, Elena Sinkovskaya, Rachel D. Seaman, Hadiza I. Galadima, Letty Romary, Jennifer Philips, Alfred Abuhamad, Oct 2019

Fetal Myocardial Performance Index In The Third Trimester Of Pregnancy: Feasibility And Reproducibility Of Conventional Spectral Doppler Versus Spectral Tissue Doppler Technique, Lea M. Porche, Elena Sinkovskaya, Rachel D. Seaman, Hadiza I. Galadima, Letty Romary, Jennifer Philips, Alfred Abuhamad,

Community & Environmental Health Faculty Publications

Objective: This study aims to compare completion rates and reproducibility of myocardial performance index (MPI) using conventional spectral Doppler versus tissue Doppler in an unselected high-risk third trimester population.

Study Design: This was a prospective cross-sectional study of high-risk pregnancies at ≥28 + 0 weeks’ gestation. Conventional spectral and tissue Doppler MPI of the left ventricle (LV) and right ventricle (RV) was attempted on all patients.

Results: Seventy-nine pregnancies were evaluated. LV tissue Doppler MPI was completed more frequently than LV conventional spectral Doppler MPI (63/79, 79.7% vs. 45/79, 55.7%), p-value

Conclusion: Tissue Doppler had statistically higher completion rates than …


Recovery Priorities In Degenerative Cervical Myelopathy: A Cross-Sectional Survey Of An International, Online Community Of Patients., Benjamin Davies, Oliver Mowforth, Iwan Sadler, Bizhan Aarabi, Brian Kwon, Shekar Kurpad, James S Harrop, Jefferson R Wilson, Robert Grossman, Michael G Fehlings, Mark Kotter Oct 2019

Recovery Priorities In Degenerative Cervical Myelopathy: A Cross-Sectional Survey Of An International, Online Community Of Patients., Benjamin Davies, Oliver Mowforth, Iwan Sadler, Bizhan Aarabi, Brian Kwon, Shekar Kurpad, James S Harrop, Jefferson R Wilson, Robert Grossman, Michael G Fehlings, Mark Kotter

Department of Neurosurgery Faculty Papers

OBJECTIVES: To establish the recovery priorities of individuals suffering with degenerative cervical myelopathy (DCM).

DESIGN: A cross-sectional, observational study.

SETTING: Patients from across the world with a diagnosis of DCM accessed the survey over an 18-month period on Myelopathy.org, an international myelopathy charity.

PARTICIPANTS: 481 individuals suffering from DCM completed the online survey fully.

MAIN OUTCOME MEASURES: Functional recovery domains were established through qualitative interviews and a consensus process. Individuals were asked about their disease characteristics, including limb pain (Visual Analogue Scale) and functional disability (patient-derived version of the modified Japanese Orthopaedic Association score). Individuals ranked recovery domains (arm and …


What Is The Smartpill®?, Christina Ciccone, Pul Lee, Kimberly Loughlin, David Koh Oct 2019

What Is The Smartpill®?, Christina Ciccone, Pul Lee, Kimberly Loughlin, David Koh

Pharmacy and Wellness Review

The SmartPill® is a new, noninvasive technology to evaluate the gastrointestinal tract. It is a nondigestible capsule that migrates through the gastrointestinal tract to measure pH, pressure, and temperature. It was approved by the FDA in 2006 for the evaluation of colonic transit time in patients with chronic constipation and to evaluate gastric transit time in patients with suspected gastroparesis. Other currently used gastrointestinal monitoring systems have some disadvantages, and the SmartPill® is suggested as an alternative. The SmartPill® has also been used for research purposes in various studies and has the potential to be used in diagnosis and monitoring …


Combating Antibiotic Resistance In The 21st Century, Kevin Krivanek, Brian Heilbronner, Brendan Rasor, Kelsey Lindsley, Andrew Roecker Oct 2019

Combating Antibiotic Resistance In The 21st Century, Kevin Krivanek, Brian Heilbronner, Brendan Rasor, Kelsey Lindsley, Andrew Roecker

Pharmacy and Wellness Review

Antibiotic resistance is one of the most significant challenges facing the medical community today. In response, the Centers for Disease Control and Prevention (CDC) created a list of the greatest antibiotic resistance threats, a number of which are gram-positive bacteria. The cell wall of these organisms has long been a favored target of antibiotic therapies, but the development of numerous resistance mechanisms has led to widespread resistance against nearly all major antibiotic compounds on the market. The medical community is faced with the task of developing better antibiotic compounds that preclude the spread of bacterial resistance and also increasing the …


Pain Management In Dementia Patients In Nursing Homes, Tiffany Kneuss, Kelsey Weisenburger, Hannah Stewart, Kelly Reilly Kroustos Oct 2019

Pain Management In Dementia Patients In Nursing Homes, Tiffany Kneuss, Kelsey Weisenburger, Hannah Stewart, Kelly Reilly Kroustos

Pharmacy and Wellness Review

Pain in the elderly, especially those with dementia, is often undertreated and misdiagnosed by health care professionals in the long-term care setting. Communication barriers in patients with cognitive impairment force pain assessment to rely heavily on subjective interpretation of behavioral factors due to the inability of patients to self-report pain symptoms. It is important for clinicians to develop a standard method of identifying and assessing signs of pain in patients with dementia in order to appropriately treat those experiencing discomfort. Patients with dementia who present with a sudden onset of behavioral changes should receive a comprehensive evaluation that includes a …


The Effects Of Long-Term Benzodiazepine Use And Withdrawal In The Elderly, Lydia Suchecki, Hannah Granger, Jamie Kellner, Mary Ellen Hethcox Oct 2019

The Effects Of Long-Term Benzodiazepine Use And Withdrawal In The Elderly, Lydia Suchecki, Hannah Granger, Jamie Kellner, Mary Ellen Hethcox

Pharmacy and Wellness Review

Benzodiazepines remain a commonly prescribed medication in the United States, and the high usage of this drug class is especially a concern in the elderly population for several reasons. First, elderly patients metabolize drugs differently, leading to varying responses. Age-related changes also have a significant impact on the effects of benzodiazepines. Second, elderly patients are more likely to be taking multiple centrally-acting drugs, which can further exacerbate negative effects. In regard to long-term benzodiazepine use, elderly patients experience an increased risk of cognitive impairment, motor vehicle accidents, decline in physical performance, falls and subsequent fractures, and sleep disturbances. Withdrawal is …


Current Trials And Therapies For The Treatment Of Amyotrophic Lateral Sclerosis And Frontotemporal Dementia, Adam Smith, Angela Chu, Lucy Wagala, Hannah Stewart, Lindsey Peters Oct 2019

Current Trials And Therapies For The Treatment Of Amyotrophic Lateral Sclerosis And Frontotemporal Dementia, Adam Smith, Angela Chu, Lucy Wagala, Hannah Stewart, Lindsey Peters

Pharmacy and Wellness Review

An area of health care that provides many more questions than answers includes neurodegenerative disorders. Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease, and frontotemporal dementia (FTD) are both diseases about which we know very little. However, ALS and FTD affect nearly 30,000 and 60,000 Americans respectively. Currently, there is not a cure for ALS or FTD and treatment options are aimed toward symptom management. Much of the pathophysiology of these diseases is unknown, but we do know there are genetic implications, specifically in SOD1, TARDBP and c90RF72. These mutations lead to cognitive deficits, muscle weakness and, eventually, …


Testosterone Replacement Therapy In Aging Males, Alexandra Dimit, Joelle Farano, Haley Armstrong, Michelle Musser Oct 2019

Testosterone Replacement Therapy In Aging Males, Alexandra Dimit, Joelle Farano, Haley Armstrong, Michelle Musser

Pharmacy and Wellness Review

The U.S. Food and Drug Administration (FDA) cautions health care providers and patients regarding the use of testosterone replacement therapy products for the aging process, including a decrease in muscle strength, muscle mass, and lack of energy or sexual desire, due to an increased risk of heart attacks and strokes. Testosterone replacement therapy products are indicated for genetic defects, chemotherapy damage, or damage to the hypothalamus or pituitary gland, where testosterone is produced. A patient and his team of health care professionals must seriously consider the risks and benefits when using these products for other indications. Use of testosterone replacement …


Combined Neprilysin And Angiotensin Inhibitor For The Treatment Of Heart Failure, Albert Bui, Victoria Cho, Rebecca Worden, Haley Armstrong, Rachel Pucel, Lindsey Peters Oct 2019

Combined Neprilysin And Angiotensin Inhibitor For The Treatment Of Heart Failure, Albert Bui, Victoria Cho, Rebecca Worden, Haley Armstrong, Rachel Pucel, Lindsey Peters

Pharmacy and Wellness Review

Heart failure (HF) is a highly prevalent disease state worldwide that can progress into a disabling condition. It is pertinent to have a treatment regimen that is effective in lowering the number of HF exacerbations and, therefore, hospital readmission rates. A novel medication currently in clinical trials, LCZ696, blocks both neprilysin and angiotensin type I receptors. The overall effects are an inhibition of the breakdown of natriuretic peptides which leads to a decrease in renin and aldosterone release. This, combined with the antagonization of angiotensin type I receptors, leads to a decrease in blood pressure, blood volume and systemic vascular …


Special Considerations In Pediatric Burn Patients Regarding Drug Dosage And Administration, Kelsey Lindsley, Maureen Moynihan, Angela Chu, Kristen Yaeger, Karen L. Kier Oct 2019

Special Considerations In Pediatric Burn Patients Regarding Drug Dosage And Administration, Kelsey Lindsley, Maureen Moynihan, Angela Chu, Kristen Yaeger, Karen L. Kier

Pharmacy and Wellness Review

Pediatric burn patients are a high-risk patient population to treat. These patients have altered physiologic function as a result of the burn injury, in addition to their smaller size and developing bodies. This creates unique challenges during treatment. Accommodations for these patients are made through unique drug dosages and routes of administration. When treating pediatric burn patients, properly assessing and treating pain promptly and effectively is of utmost importance. Nurses who utilize accurate and appropriate pain assessment scales will provide the best treatment of pain. Proper assessment allows the patient to receive the correct analgesic regime, ensuring a faster and …


The Role Of A Home Health Care Pharmacist-Medication Management For Patients With Feeding Tubes, Lydia Suchecki, Sabrina Hamman, Rachel Muhlenkamp, Eyob D. Adane Oct 2019

The Role Of A Home Health Care Pharmacist-Medication Management For Patients With Feeding Tubes, Lydia Suchecki, Sabrina Hamman, Rachel Muhlenkamp, Eyob D. Adane

Pharmacy and Wellness Review

Home health care is a method of medical care that patients receive inside their home under the supervision of a collaborative team of physicians, nurses, pharmacists and sometimes other health care professionals. Home health provides patients with the same standard of care that they would be receiving in a nursing home or hospital. However, the treatment and continued monitoring at home reduces health care costs and makes the patient feel more comfortable. Pharmacists analyze, resolve and prevent medication-related problems in home health care in order to minimize hospitalizations and improve patient quality of life. Pharmacist involvement with other health care …