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2019

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Full-Text Articles in Medical Specialties

Fmic Annual Report 2019 | English, French Medical Institute For Mothers And Children Jan 2019

Fmic Annual Report 2019 | English, French Medical Institute For Mothers And Children

French Medical Institute for Mothers and Children (FMIC) Archives

No abstract provided.


Changes In Vertical Jump Components Utilizing The Myvert Device In Female Collegiate D-1 Volleyball Players, Samantha Modrick Jan 2019

Changes In Vertical Jump Components Utilizing The Myvert Device In Female Collegiate D-1 Volleyball Players, Samantha Modrick

Electronic Theses and Dissertations

The purpose of this study was to determine daily and weekly variations in vertical jump (VJ) volume and VJ height over the course of a season for female collegiate division 1 volleyball players using Vert® technology. Sixteen volleyball player’s external load was monitored through jump count, average VJ height, number of VJs completed over 20-inches, and the ratio of VJ height relative to maximum tested VJ height. The VJ parameters were compared between practices and games, and between the various position groups (outside hitters, middle blockers, libero/defensive specialist, setters). A large increase in jump count observed during pre-season, peaked at …


Preoperative Mental Health Scores And Achieving Patient Acceptable Symptom State Are Predictive Of Return To Work After Arthroscopic Rotator Cuff Repair, Anirudh K. Gowd, Gregory L. Cvetanovich, Joseph N. Liu, Benedict U. Nwachukwu, Brandon C. Cabarcas, Brian J. Cole, Brian Forsythe, Anthony A. Romeo, Nikhil N. Verma Jan 2019

Preoperative Mental Health Scores And Achieving Patient Acceptable Symptom State Are Predictive Of Return To Work After Arthroscopic Rotator Cuff Repair, Anirudh K. Gowd, Gregory L. Cvetanovich, Joseph N. Liu, Benedict U. Nwachukwu, Brandon C. Cabarcas, Brian J. Cole, Brian Forsythe, Anthony A. Romeo, Nikhil N. Verma

Orthopaedics and Sports Medicine Faculty Publications

Background: The incidence of rotator cuff repairs has risen dramatically over the past 10 years, most notably in the working-class population. Return to work (RTW) is a valuable outcome measure to set patient expectations before surgery.

Purpose: To establish the rate of RTW after rotator cuff repair with respect to stratified levels of occupational demand (sedentary, light, moderate, and heavy) and to identify clinical factors significantly associated with postoperative RTW.

Study Design: Cohort study; Level of evidence, 3.

Methods: Patients who received rotator cuff repair between 2014 and 2017 were queried from a prospectively maintained institutional registry. Work status was …


A Developmental Study Of Apoptotic Markers And Histamine In Cephalopod Statocysts, Samantha Nicole Leef Jan 2019

A Developmental Study Of Apoptotic Markers And Histamine In Cephalopod Statocysts, Samantha Nicole Leef

Honors Theses and Capstones

Cephalopods can participate in complex navigation using landmarks that show context due to their statocysts. Statocysts are analogous to the vertebrate vestibular and auditory system encased in cartilage rather than bone making them more easily accessible. Age and anatomical dysfunctions are the reasons for many human vestibular malfunctions. Two of these sources are endolymph hydrops and aging. In the past, endolymph pressure changes were attributed to the ineffectual ion transport. Recent studies have illuminated the possibility of histamine receptors in the semicircular canal could be responsible for patients’ endolymph pressure changes rather than the previous belief that the pressure changes …


Impact Of Serratus Plane Block On Pain Scores And Incentive Spirometry Volumes After Chest Trauma, Nadia Hernandez, Johanna De Haan, Dallis Clendeninn, David E Meyer, Semhar Ghebremichael, Carlos Artime, George Williams, Holger Eltzschig, Sudipta Sen Jan 2019

Impact Of Serratus Plane Block On Pain Scores And Incentive Spirometry Volumes After Chest Trauma, Nadia Hernandez, Johanna De Haan, Dallis Clendeninn, David E Meyer, Semhar Ghebremichael, Carlos Artime, George Williams, Holger Eltzschig, Sudipta Sen

Faculty, Staff and Student Publications

Background: Adequate pain control is difficult to achieve in patients with multiple rib fractures (MRF). Serratus plane block (SPB) is a novel technique for alleviating rib fracture pain. Several published case reports support this hypothesis.

Purpose: The purpose of this study was to evaluate the use of SPB in MRF at our level 1 trauma center.

Methods: Our hospital’s Regional Anesthesia Registry was queried for all trauma patients with MRF who underwent SPB between August 2014 and January 2018. Data were compared in each patient as a matched pair for the time periods before and after undergoing SPB. Thirty-four patients …


The Role Of P62/Imp2 In Hepatocellular Carcinoma Progression, Mengtao Xing Jan 2019

The Role Of P62/Imp2 In Hepatocellular Carcinoma Progression, Mengtao Xing

Open Access Theses & Dissertations

The family of insulin- like growth factor 2 mRNA binding proteins (IMPs) contains three members: IMP1, p62/IMP2 and IMP3. All these proteins are oncofetal proteins, expressed during embryogenesis and lost in most tissues in adults. However, p62/IMP2 were found overexpressed in various cancers but its function in carcinogenesis remains to be investigated. Our previous studies found that p62/IMP2 was not only overexpressed in hepatocellular carcinoma (HCC) tissues, but also overexpressed in HCC cell lines. To explore the biological roles of p62/IMP2 in HCC progression, p62/IMP2 was knockout in two p62/IMP2 positive HCC cell lines (SNU449, HepG2). Due to the low …


Nitrofurantoin-Induced Radiation Recall Dermatitis., Ian Garrahy, Daniel Forman Jan 2019

Nitrofurantoin-Induced Radiation Recall Dermatitis., Ian Garrahy, Daniel Forman

Reading Hospital Internal Medicine Residency

Radiation recall dermatitis (RRD) is an inflammatory skin reaction that develops in a previously quiescent radiation field triggered most commonly by chemotherapy, particularly anthracyclines and taxanes. Radiation-recall dermatitis secondary to antibiotic therapy is quite rare. The patient is 61-year-old female with a history of squamous cell carcinoma of the left breast treated with neoadjuvant carboplatin, paclitaxel, and anthracycline chemotherapy followed by surgery and subsequent whole breast radiation 6040 cGy. Eight years after completion of her radiation she developed diffuse redness of the left breast after two doses of nitrofurantoin taken for a urinary tract infection. On examination, vital signs were …


Therapeutic Targeting Of Relaxin Signaling In Ischemic Heart Disease, Siva Teja Vk Devarakonda Jan 2019

Therapeutic Targeting Of Relaxin Signaling In Ischemic Heart Disease, Siva Teja Vk Devarakonda

Theses and Dissertations

Ischemic heart disease is characterized by reduced perfusion of oxygenated blood to the myocardium, potentially resulting in infarction upon occlusion of coronary arteries. While prompt reperfusion and advances in in-hospital care have led to a decline in short term mortality, sustained damage to the ventricle, along with reperfusion injury, can lead to progressive deterioration in cardiac function. Limiting the extent of this initial ischemia-reperfusion injury and combating the course of adverse remodeling remains the scope of several preclinical studies geared towards improving cardiac health after MI. To this, relaxin-2 – the peptide hormone that regulates maternal hemodynamic function during pregnancy …


Uncommon Misconceptions: Holding Physicians Accountable For Insemination Fraud, Jody L. Madeira Jan 2019

Uncommon Misconceptions: Holding Physicians Accountable For Insemination Fraud, Jody L. Madeira

Articles by Maurer Faculty

No abstract provided.


Commentary: Adherence With A Low-Fodmap Diet In Irritable Bowel Syndrome: Are Eating Disorders The Missing Link?, Bruno P Chumpitazi, Ligia Alfaro-Cruz, Jasmine K Zia, Robert J Shulman, Margaret M Heitkemper Jan 2019

Commentary: Adherence With A Low-Fodmap Diet In Irritable Bowel Syndrome: Are Eating Disorders The Missing Link?, Bruno P Chumpitazi, Ligia Alfaro-Cruz, Jasmine K Zia, Robert J Shulman, Margaret M Heitkemper

Articles, Abstracts, and Reports

No abstract provided.


Postoperative Intracranial Migration Of A C2 Odontoid Screw: A Case Report And Literature Review., Ankush Chandra, Seong-Jin Moon, Blake Walker, Emre Yilmaz, Marc Moisi, Robert Johnson Jan 2019

Postoperative Intracranial Migration Of A C2 Odontoid Screw: A Case Report And Literature Review., Ankush Chandra, Seong-Jin Moon, Blake Walker, Emre Yilmaz, Marc Moisi, Robert Johnson

Articles, Abstracts, and Reports

Background: Intracranial migration of odontoid screws is a rare but serious complication of anterior odontoid screw fixation not often reported in literature by neurosurgeons. Here, we describe the second case in literature of intracranial migration of an odontoid screw.

Case Description: A 64-year-old neurologically intact patient with a type II odontoid fracture secondary to trauma underwent anterior odontoid screw fixation without any intraoperative complications. He tolerated the procedure well, and postoperative imaging demonstrated near anatomic correction of the fracture with satisfactory placement of the lag screw. Unfortunately, the patient was subsequently lost to follow up and he presented 7 months …


Precision Sensorimotor Control In Aging Fmr1 Gene Premutation Carriers., Walker S Mckinney, Zheng Wang, Shannon Kelly, Pravin Khemani, Su Lui, Stormi P White, Matthew W Mosconi Jan 2019

Precision Sensorimotor Control In Aging Fmr1 Gene Premutation Carriers., Walker S Mckinney, Zheng Wang, Shannon Kelly, Pravin Khemani, Su Lui, Stormi P White, Matthew W Mosconi

Articles, Abstracts, and Reports

Background: Individuals with premutation alleles of the

Materials and Methods: 26

Results: Relative to controls, premutation carriers showed reduced rates of initial force generation during rapid motor actions and longer durations of their initial pressing with their dominant hand. During sustained force, premutation carriers demonstrated reduced force complexity, though this effect was specific to younger premutation carries during dominant hand pressing and was more severe for younger relative to older premutation carriers at low and medium force levels. Increased reaction time and lower sustained force complexity each were associated with greater CGG repeat length for premutation carriers. Increased reaction time …


Discontinuation And Switching Patterns Of Tumour Necrosis Factor Inhibitors (Tnfis) In Tnfi-Naive And Tnfi-Experienced Patients With Psoriatic Arthritis: An Observational Study From The Us-Based Corrona Registry., Philip Mease, Chitra Karki, Mei Liu, Youfu Li, Bernice Gershenson, Hua Feng, Peter Hur, Jeffrey D Greenberg Jan 2019

Discontinuation And Switching Patterns Of Tumour Necrosis Factor Inhibitors (Tnfis) In Tnfi-Naive And Tnfi-Experienced Patients With Psoriatic Arthritis: An Observational Study From The Us-Based Corrona Registry., Philip Mease, Chitra Karki, Mei Liu, Youfu Li, Bernice Gershenson, Hua Feng, Peter Hur, Jeffrey D Greenberg

Articles, Abstracts, and Reports

Objective: To examine patterns of tumour necrosis factor inhibitor (TNFi) use in TNFi-naive and TNFi-experienced patients with psoriatic arthritis (PsA) in the USA.

Methods: All patients aged ≥18 years with PsA enrolled in the Corrona Psoriatic Arthritis/Spondyloarthritis Registry who initiated a TNFi (index therapy) between March 2013 and January 2017 and had ≥1 follow-up visit were included. Times to and rates of discontinuation/switch of the index TNFi were compared between TNFi-naive and TNFi-experienced cohorts. Patient demographics and disease characteristics at the time of TNFi initiation (baseline) were compared between cohorts and between patients who continued versus discontinued their index TNFi …


A Case Report Of Thalamic Infarction After Lumbar Drain: A Unique Cause Of Perioperative Stroke?, Daniel N Kianpour, Thomas M Nguyen, Arthur M Lam Jan 2019

A Case Report Of Thalamic Infarction After Lumbar Drain: A Unique Cause Of Perioperative Stroke?, Daniel N Kianpour, Thomas M Nguyen, Arthur M Lam

Articles, Abstracts, and Reports

In the case presented, a patient has an unexplained episode of hypertension during aneurysm clipping. Following the procedure, the patient was discovered to have bilateral thalamic infarctions unrelated to the vascular location of the aneurysm. After a review of the case, it becomes apparent that intracranial hypotension caused by lumbar over drainage of cerebrospinal fluid (CSF) is the likely cause of both the episode of intraoperative hypertension and the thalamic infarcts. It is often presumed that having an open dura protects against intracranial hypotension and subsequent herniation. We present this case to suggest that opening the dura might not be …


Focused Transcranial Ultrasound For Treatment Of Neurodegenerative Dementia., Natalie Eleanor Nicodemus, Sergio Becerra, Taylor P Kuhn, Hannah R Packham, John Duncan, Kennedy Mahdavi, Jessica Iovine, Santosh Kesari, Scott Pereles, Mike Whitney, Michael Mamoun, Daniel Franc, Alexander Bystritsky, Sheldon Jordan Jan 2019

Focused Transcranial Ultrasound For Treatment Of Neurodegenerative Dementia., Natalie Eleanor Nicodemus, Sergio Becerra, Taylor P Kuhn, Hannah R Packham, John Duncan, Kennedy Mahdavi, Jessica Iovine, Santosh Kesari, Scott Pereles, Mike Whitney, Michael Mamoun, Daniel Franc, Alexander Bystritsky, Sheldon Jordan

Articles, Abstracts, and Reports

Introduction: Preclinical studies support investigation of focused ultrasound for breakdown of cerebral pathologies in neurodegenerative conditions including Alzheimer's disease (AD) and Parkinson's disease (PD).

Methods: A focused transcranial Doppler device with probes (2 MHz, 520 mW/cm

Results: Of all, 62.5% of patients had one or more improved cognitive scores without data incongruence, 87% had stable or improved fine motor scores, and 87.5% had stable or improved gross motor scores. No adverse events were reported.

Discussion: The safety of focused transcranial Doppler and possible enhancement in patient functioning were suggested by outcome data.


Prospective Observational Study In Patients With Obstructive Lung Disease: Novelty Design, Helen K. Reddel, Maria Gerhardsson De Verdier, Alvar Agustí, Gary Anderson, Richard Beasley, Elisabeth H. Bel, Christer Janson, Barry Make, Richard J. Martin, Ian Pavord, David Price, Christina Keen, Asparuh Gardev, Stephen I. Rennard, Alecka Sveréus, Aruna T. Bansal, Lance Brannman, Niklas Karlsson, Javier Nuevo, Fredrik Nyberg, Simon S. Young, Jørgen Vestbo Jan 2019

Prospective Observational Study In Patients With Obstructive Lung Disease: Novelty Design, Helen K. Reddel, Maria Gerhardsson De Verdier, Alvar Agustí, Gary Anderson, Richard Beasley, Elisabeth H. Bel, Christer Janson, Barry Make, Richard J. Martin, Ian Pavord, David Price, Christina Keen, Asparuh Gardev, Stephen I. Rennard, Alecka Sveréus, Aruna T. Bansal, Lance Brannman, Niklas Karlsson, Javier Nuevo, Fredrik Nyberg, Simon S. Young, Jørgen Vestbo

Journal Articles: Pulmonary & Critical Care Med

Asthma and chronic obstructive pulmonary disease (COPD) have overlapping clinical features and share pathobiological mechanisms but are often considered distinct disorders. Prospective, observational studies across asthma, COPD and asthma-COPD overlap are limited. NOVELTY is a global, prospective observational 3-year study enrolling ∼12 000 patients ≥12 years of age from primary and specialist clinical practices in 19 countries (ClinicalTrials.gov identifier: NCT02760329). NOVELTY's primary objectives are to describe patient characteristics, treatment patterns and disease burden over time, and to identify phenotypes and molecular endotypes associated with differential outcomes over time in patients with a diagnosis/suspected diagnosis of asthma and/or COPD. NOVELTY …


Risk Factors For Gestational Diabetes In Upstate New York Women & Implications For Practice, Margaret Versteegen Jan 2019

Risk Factors For Gestational Diabetes In Upstate New York Women & Implications For Practice, Margaret Versteegen

Legacy Theses & Dissertations (2009 - 2024)

Gestational diabetes mellitus (GDM) is a form of diabetes, or abnormal blood glucose (sugar) metabolism, diagnosed during pregnancy. Pregnant, non-diabetic women who are initially noted to experience high blood glucose levels during their pregnancy are considered to have GDM (ADA, 2016b). GDM has significant implications for infant and maternal morbidity and mortality, with adverse pregnancy outcomes such as infant macrosomia, difficult birth requiring cesarean section, and postpartum hemorrhage (Kamana, Shakya, & Zhang, 2015). In the majority of cases, GDM goes away once the baby is born, but around 5-10% of women with GDM go on to have type 2 diabetes …


Sexual Behaviours Of Adolescents In Creek Town, Cross River State, Nigeria, Kabiru K. Salami, Rowland E. Edet Jan 2019

Sexual Behaviours Of Adolescents In Creek Town, Cross River State, Nigeria, Kabiru K. Salami, Rowland E. Edet

Department of Sociology: Faculty Publications

Risky sexual behaviors of adolescents in Creek Town have not been fully profiled. This study investigated the sexual behaviors of adolescents and their various dimensions in Creek Town, in Cross River State, Nigeria. This cross-sectional survey design adopted multi-stage sampling procedure to administer a 112-items questionnaire to 422 adolescents, to elicit information on their sexual behaviors and practices. Four focus group discussion sessions were also conducted with in-school and out-of-school adolescents. The mean age of adolescents was 17 years. Majority (65.4%) of the adolescents were sexually active. The mean age at sexual debut was 15 years for both male and …


Comparison Of Quantitative Analysis To Qualitative Analysis For Interpretation Of Lower‑Limb Lymphoscintigraphy, Edward Nganga, Khalid Makhdomi Jan 2019

Comparison Of Quantitative Analysis To Qualitative Analysis For Interpretation Of Lower‑Limb Lymphoscintigraphy, Edward Nganga, Khalid Makhdomi

Imaging & Diagnostic Radiology, East Africa

Qualitative analysis of lymphoscintigrams is subject to wide variability and may miss subtle differences in ilioinguinal uptake between normal and abnormal limbs. This study compared quantitative analysis to qualitative analysis of lower‑limb lymphoscintigraphy in diagnosing lymphedema. Fifty‑two lymphoscintigrams performed using standardized protocol, 99‑metastable technetium nanocolloid intradermal injection at the first interdigital space, were analyzed quantitatively. Fifty‑three normal and 51 abnormal limbs were analyzed. For each limb, a region of interest (ROI) was drawn around the injection site, and ilioinguinal nodes on the 1.5 h static images and the counts in these ROIs were recorded. Percentage ilioinguinal nodes uptake was then …


การเปรียบเทียบการเกิดภาวะเอียงของกระดูกเชิงกรานขณะวิ่งที่ระดับความหนักปานกลางในกลุ่มนักวิ่งมือใหม่และนักวิ่งสันทนาการเพศหญิง, หทัยภัทร ทิพยุทธ Jan 2019

การเปรียบเทียบการเกิดภาวะเอียงของกระดูกเชิงกรานขณะวิ่งที่ระดับความหนักปานกลางในกลุ่มนักวิ่งมือใหม่และนักวิ่งสันทนาการเพศหญิง, หทัยภัทร ทิพยุทธ

Chulalongkorn University Theses and Dissertations (Chula ETD)

การวิจัยครั้งนี้มีวัตถุประสงค์เพื่อศึกษาผลของการวิ่งที่ระดับความหนักปานกลางต่อระยะเวลาการเกิดภาวะเอียงของกระดูกเชิงกราน (pelvic drop) ในนักวิ่งมือใหม่ และนักวิ่งสันทนาการเพศหญิง และศึกษาความสัมพันธ์ระหว่างแนวการเอียงของกระดูกเชิงกราน (pelvic alignment)กับอัตราการเต้นของหัวใจ (heart rate; HR), การใช้ออกซิเจน (VO2 uptake), ค่าความรู้สึกเหนื่อย (Rating of Perceived Exertion; RPE), ค่าความรู้สึกล้าของขา (Rating of Perceived Exertion for legs; RPElegs) และความล้าของกล้ามเนื้อ Gluteus medius และ Gluteus maximus กลุ่มตัวอย่างในงานวิจัยครั้งนี้อายุระหว่าง 18 - 35 ปี เป็นนักวิ่งมือใหม่ (ประสบการณ์น้อยกว่า 1 ปี) 27 คน และนักวิ่งสันทนาการ (ประสบการณ์ 2 - 4 ปี) 27 คน ซึ่งทั้งสองกลุ่มได้รับการทดสอบประสิทธิภาพการใช้ออกซิเจนสูงสุด (VO2max) และวิ่งบนลู่วิ่ง 30 นาที ที่ระดับความหนักปานกลางที่อัตราเร็วที่เลือกเอง (นักวิ่งมือใหม่; 5.87 ± 0.62 กม./ชม. vs. นักวิ่งสันทนาการเพศหญิง; 6.44 ± 0.58 กม./ชม.) โดยอยู่ในช่วงอัตราการเต้นหัวใจที่ 40 - 59% ของอัตราการเต้นหัวใจสำรองสูงสุด (heart rate reserve; HRR) ขณะทดสอบบนลู่วิ่ง 30 นาที นักวิ่งทั้งสองกลุ่มจะถูกบันทึกค่าอัตราการเต้นของหัวใจ, การใช้ออกซิเจน, ค่าความรู้สึกเหนื่อย, ค่าความรู้สึกล้าของขา และวัดการทำงานของกล้ามเนื้อ (muscle activity) จากสัญญาณไฟฟ้า (electromyography; EMG) ที่กล้ามเนื้อ Gluteus medius และ Gluteus maximus ทุก ๆ …


Diagnosis And Rehabilitation Of Multiple Hip Pathologies In A Division I Football Player: A Case Study, Kelsey E. Sanders Jan 2019

Diagnosis And Rehabilitation Of Multiple Hip Pathologies In A Division I Football Player: A Case Study, Kelsey E. Sanders

Electronic Theses and Dissertations

Objective: To present a diagnosis and rehabilitation plan for femoroacetabular impingement (FAI), labral tear, and sports hernia in a Division I college football player. Background: A 21-year-old NCAA Division I college football player experienced a rare combination diagnosis of hip FAI, labral tear and sports hernia. Overlapping signs and symptoms proved difficult to conclude a diagnosis. The patient underwent three months of conservative treatment with no relief before electing to undergo surgery. Differential Diagnosis: Hip flexor strain, osteitis pubis. Treatment: A combination of conservative treatment such as activity modification, anti-inflammatories, therapeutic modalities, injections, and rehabilitation were unsuccessful in relieving symptoms …


Does Preprandial Oral Lactase Supplement Reduce Abdominal Pain In Lactose-Intolerant Adult Patients After A Lactose-Containing Meal?, Margaryta Tolchynska Jan 2019

Does Preprandial Oral Lactase Supplement Reduce Abdominal Pain In Lactose-Intolerant Adult Patients After A Lactose-Containing Meal?, Margaryta Tolchynska

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not preprandial oral lactase supplement reduces abdominal pain in lactose-intolerant adult patients after a lactose-containing meal.

STUDY DESIGN: A systematic review of three randomized, blinded, controlled primary research studies published between the years of 2010 and 2018.

DATA SOURCES: One randomized controlled trial (RCT), one randomized comparative study, and one randomized crossover study evaluating the efficacy of 9,000 units of preprandial oral lactase supplement in reducing abdominal pain due to lactose intolerance (LI). All studies were published in peer-reviewed journals and found via the use of PubMed, …


Is Botulinum Toxin Injection Effective In Reducing Pain In Patients Diagnosed With Plantar Fasciitis?, David A. Fry Jan 2019

Is Botulinum Toxin Injection Effective In Reducing Pain In Patients Diagnosed With Plantar Fasciitis?, David A. Fry

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not botulinum toxin injection is effective in reducing pain in patients diagnosed with plantar fasciitis.

STUDY DESIGN: Review of three randomized controlled trials (RCTs) comparing the efficacy of botulinum toxin injections versus corticosteroid injections for improving pain and dysfunction in those diagnosed with plantar fasciitis.

DATA SOURCES: All articles were presented in English and were taken from peer reviewed sources using PubMed. All articles were published from 2012-2017.

OUTCOMES: Outcomes of investigation measured are pain score measured using the VASvisual analog scale and Foot Health Status Questionnaire. …


Is There A Greater Statistically Significant Difference In The Clearance Or Partial Clearance Of Anogenital/Genital Warts When It Comes To Combination Therapies That Include Cryotherapy Versus Cryotherapy Alone?, Erika Burbano Jan 2019

Is There A Greater Statistically Significant Difference In The Clearance Or Partial Clearance Of Anogenital/Genital Warts When It Comes To Combination Therapies That Include Cryotherapy Versus Cryotherapy Alone?, Erika Burbano

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine if there is a statistically significant difference in using combination therapies that include cryotherapy vs. cryotherapy alone in the clearance of genital/anogenital warts.

STUDY DESIGN: Systematic review of three peer reviewed primary studies that were published between 2009-2014.

DATA SOURCES: Review of a double-blind placebo-controlled study, a single-blinded randomized controlled study, and a randomized clinical comparative study from 2011. All sources were selected from PubMed based on the applicability to the clinical question and how accurately they answered the question regarding the patient population

OUTCOMES: The outcomes of investigation …


Do Adults Undergoing Minimally Invasive Quadriceps-Sparing Total Knee Arthroplasty Have Less Of A Risk Of Developing A Postoperative Deep Venous Thrombosis As Compared To Patients Undergoing A Standard Medial Parapatellar Total Knee Arthroplasty?, Jessica Cataldo-Ramirez Jan 2019

Do Adults Undergoing Minimally Invasive Quadriceps-Sparing Total Knee Arthroplasty Have Less Of A Risk Of Developing A Postoperative Deep Venous Thrombosis As Compared To Patients Undergoing A Standard Medial Parapatellar Total Knee Arthroplasty?, Jessica Cataldo-Ramirez

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Do adults undergoing minimally invasive quadriceps-sparing total knee arthroplasty have less of a risk of developing a postoperative deep venous thrombosis as compared to patients undergoing a standard medial parapatellar total knee arthroplasty?”

STUDY DESIGN: A review of one case series published in 2007 and two randomized controlled trials published in 2014.

DATA SOURCES: Primary literature found in PubMed that compared the surgical outcomes of minimally invasive quadriceps-sparing total knee arthroplasty to standard medial parapatellar total knee arthroplasty.

OUTCOME MEASURED: Postoperative deep venous thrombosis development.

RESULTS: …


Is Lifitegrast 5.0% Ophthalmic Solution Effective In Improving Eye Dryness And Safe, In Terms Of Ocular Adverse Effects, In Adults 18 Years Or Older With Dry Eye Disease?, Aubrey E. Cole Jan 2019

Is Lifitegrast 5.0% Ophthalmic Solution Effective In Improving Eye Dryness And Safe, In Terms Of Ocular Adverse Effects, In Adults 18 Years Or Older With Dry Eye Disease?, Aubrey E. Cole

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not lifitegrast 5.0% ophthalmic solution is effective in improving eye dryness and safe, in terms of ocular adverse effects, in adults 18 years or older with dry eye disease (DED).

Study Design: Systematic review of three primary double-blinded, randomized placebocontrolled trials that were published in peer-reviewed journals between 2014-2017.

Data Sources: Studies were obtained through the PubMed database based on relevance to the clinical question and evaluation of patient-oriented outcomes.

Outcomes Measured: Efficacy of lifitegrast treatment was measured based on the eye dryness …


Does Botulinum Toxin A Injections Into The Pelvic Floor Muscles Of Women With Chronic Genitopelvic Pain And Vaginal Spasm Improve Pain And Sexual Functioning?, Emily R. Broadbent Jan 2019

Does Botulinum Toxin A Injections Into The Pelvic Floor Muscles Of Women With Chronic Genitopelvic Pain And Vaginal Spasm Improve Pain And Sexual Functioning?, Emily R. Broadbent

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this evidenced based medicine review is to determine whether or not botulinum toxin A injections into the pelvic floor muscles of women with chronic genitopelvic pain and vaginal spasm improve pain and sexual functioning.

STUDY DESIGN: Review of two double blind randomized controlled trials and one case series from peer reviewed journals published between 2006-2011.

DATA SOURCES: Two randomized controlled trials and one case series were found using PubMed, Google Scholar, and Cochrane Library.

OUTCOMES MEASURED: All three studies measured pain and sexual functioning using selfreported surveys including the visual analog scale for pain, Female Sexual …


Consent For Emergency Treatment: Emergency Department Patient Recall And Understanding, Ashley Lafountain Jan 2019

Consent For Emergency Treatment: Emergency Department Patient Recall And Understanding, Ashley Lafountain

Scholarship in Medicine - All Papers

Informed consent is an important ethical and legal requirement that underlies the concept of patient autonomy. This prospective survey study was conducted to assess patient recall and understanding of consent for treatment in adult emergency department (ED) patients at an urban level 1 trauma center with annual volume of 95,000, Miami Valley Hospital. Out of a total 293 patients, most individuals reported only receiving a verbal explanation of the consent document (45%) or not reading the document at all (36%). About half of the patients recalled consenting to treatment (N=144, 49%) and over one third of patients could not recall …


Factors Associated With Chest Tube Placement In Blunt Trauma Patients With An Occult Pneumothorax, Michael Paplawski, Swapna Munnangi, Jody C. Digiacomo, Edwin Gonzalez, Ashley Modica, Shawndeep S. Tung, Catherine Ko Jan 2019

Factors Associated With Chest Tube Placement In Blunt Trauma Patients With An Occult Pneumothorax, Michael Paplawski, Swapna Munnangi, Jody C. Digiacomo, Edwin Gonzalez, Ashley Modica, Shawndeep S. Tung, Catherine Ko

Surgery Faculty Publications

Background. An occult pneumothorax is identified by computed tomography but not visualized by a plain film chest X-ray. The optimal management remains unclear. Methods. A retrospective review of an urban level I trauma center’s trauma registry was conducted to identify patients with occult pneumothorax over a 2-year period. Factors predictive of chest tube placement were identified using univariate and multivariate logistic regression analysis. Results. A total of 131 patients were identified, of whom 100 were managed expectantly with an initial period of observation. Ultimately, 42 (32.0%) patients received chest tubes and 89 did not. The patients who …


Review Of Procedures For Reconstruction Of Soft Tissue Chest Wall Defects Following Advanced Breast Malignancies, Alicia Billington, Deniz Dayicioglu, Paul Smith, John Kiluk Jan 2019

Review Of Procedures For Reconstruction Of Soft Tissue Chest Wall Defects Following Advanced Breast Malignancies, Alicia Billington, Deniz Dayicioglu, Paul Smith, John Kiluk

Surgery Faculty Publications

The purpose of this article is to review closure options for complex chest wounds in patients with locally advanced breast cancer. Experiences of the plastic and oncologic surgery teams at Moffitt Cancer Center were reviewed, and the literature researched for various surgical options of complex chest wound closure. Multiple treatment modalities exist for reconstruction of complex chest wall wounds with the external oblique and V-Y latissimus dorsi musculocutaneous advancement flaps serving as workhorses in reconstruction. Treatment of cancer has moved from simply a surgical solution to include other modalities such as hormonal therapy, chemotherapy, and radiation—the latter 2 having serious …