Medical Specialties Commons^™

A 30 Years Old Woman With Sepsis, Skin And Soft Tissueinfection, And Obesity, Franzeska Adm Widinartasari, Muhammad Ali Sodiq, Muchlis Au Sofro

Jurnal Penyakit Dalam Indonesia

Obesity increases morbidity and mortality through its multiple efects on nearly every human system. Obesity has efect on the immune response which leads to susceptibility to infections. ß lactamases are bacterial enzymes that inactivate ß-lactam antibiotics by hydrolysis. One group of ß lactamases, extended-spectrum ß lactamases (ESBLs), have the ability to hydrolyse and cause resistance to various types of the newer ß-lactam antibiotics. The management of skin and soft tissue infection with polymicrobial infection and multi drug resistance can be challenging problem. We present a case of an obese patient with polymicrobial SSTI. bPatient showed clinical sign of sepsis with …

Diagnostic Approach And Treatment Of Dieulafoy's Lesion, Anshari Saifuddin, Kaka Renaldi, Indah Situmorang

Jurnal Penyakit Dalam Indonesia

Dieulafoy’s lesion is a rare cause of upper gastrointestinal bleeding but become an important etiology. Pathogenesis of the disease evolved from earlier of its invention till now. It has been stated in recent study that the etiology of this disease is vary, from age to genetic. Size and arteriol configuration abnormality has been known as the main pathogenesis of the disease. Endoscopic procedure become the primary diagnostic tool, which effectiveness reached more than 90%. However, in some situation, it’s difficult to find the abnormality by endoscopic procedure. Hemostatic procedure via endoscopy is the main therapy of Dieulafoy’s lesion, which has …

Keberhasilan Pengobatan Antiretroviral (Arv), Teguh H. Karyadi

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Approach To Diagnosis And Treatment Of Drug Allergy, Roy Akur Pandapotan, Iris Rengganis

Jurnal Penyakit Dalam Indonesia

Drug allergy is a serious medical problem. Drug allergy can be defined as an adverse drug reaction involving immunological mechanism. However, it is not easy to decide whether an adverse drug reaction is an allergic reaction, and it requires a systematically diagnostic approach. Beside a thorough history taking and physical examination, there are general and specific laboratory examination to investigate drug allergy which can be done in vivo, in vitro, or biopsy. The management of drug allergy include the avoidance of the precipitating event, and specific methods to reduce the drug reaction which include threating through, dosing test, desensitization, and …

Challenges In Providing Treatment Of Severe Malaria Case In Adistrict Hospital Of Remote Area In Indonesia, Dimas Priantono, Asep Purnama, Erni Juwita Nelwan

Jurnal Penyakit Dalam Indonesia

Severe Malaria is commonly found due to Plasmodium falciparum infection, which is causing high mortality in patient. A Severe case might be difficult to treat optimally in the remote settings area that could be due to lack in awareness of disease manifestation and inadequate diagnostic facilities. We report a case of Severe Malaria Falciparum infection, confirmed by blood smear examination of Plasmodium falciparum (Pf) parasites. Patient had received Artemicinin Based Combination Therapy (ACT), which consisted of dihydroartemisinin (DHA)-piperaquine and primaquine (PQ) with no clear clinical and microscopy improvement. The second line anti malaria consisted of quinine, doxycycline, and PQ was …

Cost Of Care Saving Of Terminal Cancer Adult Patient Usingpalliative Care Consultation In Cipto Mangunkusumo Hospital, Rudi Putranto, Laksono Trisnantoro, Yos Hendra

Jurnal Penyakit Dalam Indonesia

Introduction. Terminal cancer patients was increasing in Indonesia, and need attention to approach palliative and end of life care. Terminal cancer management was burden the hospital, because it causes high costly and the length of stay This study aimed to get a general picture of service palliative at Cipto Mangunkusumo, then to evaluate the relationship hospitalization and rates of inpatient services people with terminal cancer adults who received the intervention palliative care and to evaluate the relationship variable rates for accommodation (room), doctor visit, procedure/surgery, medicines and consumables, laboratory and radiology to palliative interventions in patients with terminal cancer in …

The Association Between Vitamin D 25(Oh)D Level Andalbuminuria In Type 2 Diabetes Mellitus, Tities Anggraeni Indra, Aida Lydia, Dyah Purnamasari, Siti Setiati

Jurnal Penyakit Dalam Indonesia

Introduction. Vitamin D 25(OH)D deficiency was reported as a possible risk factor for the development of diabetic nephropathy in several epidemiologic studies. Whether vitamin D 25(OH)D deficiency plays a role in the development of diabetic nephropathy in Indonesia is unknown. This study aims to determinate the association between vitamin D 25(OH)D level with albuminuria in patients with type 2 diabetes mellitus in Indonesia. Methods. A cross-sectional study was conducted in 96 patients with type 2 diabetes mellitus at outpatient clinic of MetabolicEndocrine Cipto Mangunkusumo Hospital. Serum vitamin D level was assessed using Diasorin kit with CLIA method, while albuminuria was …

Risk Factors Of Antituberculosis Induced-Hepatotoxicity Amonghiv/Aids Patients, Lies Luthariana, Teguh H. Karjadi, Irsan Hasan, C. Martin Rumende

Jurnal Penyakit Dalam Indonesia

Introduction. Antituberculosis (ATT) induced hepatotoxicity is commonly found among HIV/AIDS patients. Several risk factor related to drug-induced hepatotoxicity such as alcoholism, hepatitis B or hepatitis C infection, abnormal baseline aminotransferase/bilirubin, poor nutritional status and concomitant hepatotoxic drugs consumption, are usually found in these patients. This study was conducted to evaluate risk factor of ATT-induced hepatotoxicity in HIV/AIDS patients. Methods. This is a case control retrospective study with matching of age, sex, antituberculosis regimen, and alcohol consumption. Risk factors evaluated are hepatitis C and hepatitis B coinfection, concomitant hepatotoxic drugs consumption, abnormal baseline aminotransferase and or bilirubin. Results. We collected data …

Predictors Of Virological Failure In Hiv Patients Receiving Firstline Antiretroviral Therapy With Good Adherence, Farid Kurniawan, Samsuridjal Djauzi, Evy Yunihastuti, Pringgodigdo Nugroho

Jurnal Penyakit Dalam Indonesia

Introduction. Antiretroviral therapy (ART) effectively suppress HIV replication. Viral load (VL) measurement is better predictor than clinical or immunological criteria to evaluate success or failure of ART. However, in country with limited resources, viral load measurement is not easily accessible by HIV patients receiving ART. Therefore, it is necessary to know which factors that can predict virological failure. In previous studies, adherence was an important factor for suppression of HIV viral load. This study is aimed to know predictors of virological failure in HIV patients receiving recent first line ART regimen with good adherence in Indonesia. Methods. A retrospective cohort …

Effect Of Structured Education And Antihypertensive Medicationsadherence To Decrease Blood Pressure For Hypertension Inelderly: A Randomized Controlled Trial, Ayatullah Khomaini, Siti Setiati, Aida Lydia, Esthika Dewiasty

Jurnal Penyakit Dalam Indonesia

Introduction. Hypertension is one of the important problems in elderly due to high impact of cardiovascular complications. Education and antihypertensive medication adherence are considered as influence factors in a holistic and comprehensive hypertension treatment. This study was conducted to determine the effect of structured education and antihypertensive medication adherence in decreasing blood pressure as part of the hypertension treatment in elderly patients. Methods. A randomized clinical trial was conducted in October 2012 to February 2013 on hypertensive elderly patients at Cipto Mangunkusumo hospital, Jakarta. Subjects were divided into 3 groups: group I was received structured education and checklist, group II …

Factors Related To 30 Day Mortality In Critically Ill Patients Withinvasive Candidiasis In Cipto Mangunkusumo Hospital, Ardi Ardian, Ceva W. Pitoyo, Dita Adhitianingsih, Widayat Djoko Santoso, Siti Setiati

Jurnal Penyakit Dalam Indonesia

Introduction. Mortality rate of invasive candidiasis is still high, approximately 30-70%. Every study has a variety mortality rate depend on study design and sample. There is no data in Indonesia about profile and mortality factors analysis in critically ill patients with invasive candidiasis. Methods. The Study design was cross sectional. We studied 102 hospitalized critically ill patients with invasive candidiasis. The demographic, clinical and laboratory data, the risk factors for invasive candidiasis and the outcome of each patient in 30 days were recorded. An analysis bivariate with chi square or Fisher’s test was carried out to analyse some factors such …

Fungsi Ginjal Dan Kematian Akibat Sindrom Koroner Akut, Eka Ginanjar

Jurnal Penyakit Dalam Indonesia

Penyakit kardiovaskuler merupakan salah satu penyebab kematian utama di dunia. World Health Organization (WHO) melaporkan 17,5 juta orang meninggal akibat penyakit kardiovaskuler pada tahun 2012, atau diperkirakan 3 dari 10 kematian terjadi akibat penyakit jantung.

Factors Related To Diagnosis Of Community-Acquired Pneumonia In The Elderly, Elza Febria Sari, C. Martin Rumende, Kuntjoro Harimurti

Jurnal Penyakit Dalam Indonesia

Introduction. Diagnosing community-acquired pneumonia (CAP) in the elderly remains a clinical challenge for various reasons. The clinical manifestation in the elderly is not frank and atypical manifestations, e.g. falls, decrease of functional status and food intake or urinary incontinence, may be present. These reasons may be associated with under or over diagnosis, which consequently contribute to the higher observed mortality rate in the elderly population with CAP. Study about factors related to diagnosis of CAP in the elderly was ra rely performed.

Methods. From January to October 2010, 158 elderly patients suspected of having pneumonia at RSCM were registered. Relationship …

Estimated Glomerular Filtration Rate (Egfr) As An In-Hospital Mortality Predictor In Acute Coronary Syndrome Patients In Iccu, Esthika Dewiasty, Idrus Alwi, Dharmeizar Dharmeizar, Kuntjoro Harimurti

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Correlation Of Forced Expiratory Volume In 1 Second Prediction With Mean Pulmonary Arterial Pressure Using Echocardiography In Stable Chronic Obstructive Pulmonary Disease, Munadi Munadi, M. Yamin, Anna Ujainah, Cleopas Martin Rumende

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Prevention Of Hepatitis B Vertical Transmission: Focus On Antenatal Antiviral Administration, Anandhara Indriani Khumaedi, Rino Alvani Gani, Irsan Hasan

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Correlation Of Frailty Status With Influenza Vaccine Seroconversion And Seroprotection Among Elderly Population, Sukamto Koesnoe, Ummu Habibah, Edy Rizal Wahyudi, Murdani Abdullah

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Auto Immune Hemolytic Anemia (Aiha) Patients Profile And Treatment Response To Corticosteroids In Cipto Mangunkusumo Hospital, Wulyo Rajabto, Djumhana Atmakusuma, Siti Setiati

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Diagnosis And Treatment Of Acquired Hemophilia A (Aha) With Bullous Pemphigoid, Rasco Sandy Sihombing, Henry Ratno Diono Silalahi, Hamzah Shatri, Lugyanti Sukrisman, Ikhwan Rinaldi, Findy Prasetyawati, Endy Novianto, Em Yunir

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Bone Mass Density In Hiv/Aids Patients, Nadia Ayu Mulansari, Nanang Sukmana, Bambang Setyohadi, Siti Setiati

Jurnal Penyakit Dalam Indonesia

No abstract provided.

The Effect Of Long-Term Proton Pump Inhibitor Use On Frailtysyndrome In Elderly Patients, Stephanie Dewi, Purwita W. Laksmi, Ari Fahrial Syam

Jurnal Penyakit Dalam Indonesia

Introduction. Frailty syndrome, the newest elderly health predictor, associated with higher morbidity and mortality. PPI are often used in elderly due to presence of upper gastrointestinal complaints, and relates with polypharmacy as one of the risk factor for frailty syndrome. There is no study of the relationship between long term PPI use and frailty syndrome in elderly. Methods. A case control study included subjects 60 years and above with good cognitive status. All subjects with history of hypersensitivity of PPI were excluded. Elderly who were frail based on FI-40 item were defined as cases, while individuals that were not frail …

Diagnostic And Treatment Problems Of Primary Sclerosingcholangitis, Rezky Aulia Nurleili, Intan Airlina F, Anna Mira Lubis

Jurnal Penyakit Dalam Indonesia

Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with high incidence reported in America (1/100.000 population), but there is still no data available in Indonesia. The best management of this disease is still not found. Thus, in this article author will discuss about the case of PSC in 49-years male patients hospitalized in Cipto Mangunkusumo hospital Jakarta and its treatment.

Change Of Interleukin-6, C-Reactive Protein And Soluble Vascularcell Adhesion Molecule-1 Concentrations In Hemodialysispatients With Reprocessed Dialyzer, Pringgodigdo Nugroho, Aida Lydia, Marulam Mp Panggabean

Jurnal Penyakit Dalam Indonesia

Introduction. Cardiovascular disease is a major cause of morbidity and mortality in hemodialysis patients. In addition to traditional cardiovascular risk factors, non-traditional cardiovascular risk factors such as inflammation were also involved. Reprocessed dialyzer has been showed to induce less inflammation than new dialyzer, but data in diacetate cellulose membrane have not been presented. Methods. Twenty hemodialysis (HD) patients were enrolled. Pre and post study design was conducted to know post dialysis concentration changes of interleukin 6 (IL-6), C-reactive protein (CRP) and soluble vascular cell adhesion molecule-1 (sVCAM-1) at reuse 0, 5 and 10. Patients were recruited if medically stable, on …

The Role Of Hydration And N-Acetyl Cysteine Combination In 48hours Contrast-Induced Nephropaty After Percutaneous Coronaryintervention In Stage Three Chronic Kidney Disease Patients, Lydia D. Simatupang, Endang Susalit, Ika Prasetya Wijaya

Jurnal Penyakit Dalam Indonesia

Introduction. Contrast Induced Nephropathy (CIN) after percutaneous coronary intervention (PCI) is common in stage 3 chronic kidney disease (CKD) patients. While there is no cure for CIN and some cases are fatal for the kidney or even life, it is preventable. Eventhough controversial, hydration and N-Acetyl Cysteine (NAC) are modalities to prevent CIN. Not having a certain guideline to prevent CIN in Integrated Cardiac Services (ICS) Cipto Mangunkusumo Hospital for PCI patients generates interest to study it. Methods. A prospective cohort is conducted to evaluate plasma creatinine before and 48 hours after PCI, meanwhile recording whom is given combined hydration …

Benarkah Dialiser Proses Ulang Memicu Inflamasi?, Suhardjono Suhardjono

Jurnal Penyakit Dalam Indonesia

No abstract provided.

The Difference Of C-Reactive Protein Levels In Acute Fever Causedby Dengue And Typhoid Infections, Adeputri Tanesha Idhayu, Lie Khie Chen, Suhendro Suhendro

Jurnal Penyakit Dalam Indonesia

Introduction. Dengue infection and typhoid fever are endemic disease in Indonesia. But in the early days of onset sometimes it is difficult to distinguish them. A simple modality test is needed to support the diagnosis. C-Reactive Protein (CRP) is an affordable, fast and relatively less expensive diagnostic tool to diagnose the causes of acute fever. This study was aimed to determine the differences of CRP level in the acute febrile caused by dengue infection or typhoid fever. Methods. A cross sectional study has been conducted among acute febrile patients with diagnosis of dengue fever/ dengue hemorrhagic fever or typhoid fever …

Factors Related To Delayed Antiretroviral Therapy Initiation Inhiv Patients, Dwi Rahayu Nlp, Teguh H. Karjadi, Erni J. Nelwan

Jurnal Penyakit Dalam Indonesia

Introduction. Increase access towards antiretroviral therapy (ART) contribute to global decrease of HIV-associated morbidity and mortality. Time to initiation of ART in eligible HIV-infected patients is associated with reduction in mortality and morbidity. Delayed initiation of antiretroviral therapy can lead to increased of mortality rate more than 10% compare to early initiation. Methods. This study was a cross sectional study among adult HIV patients in Out-patient Clinic of HIV Integrated Clinic Cipto Mangunkusumo General Hospital who started ARV therapy for the first time (ART-naïve patients) enrolled from January 2013 to December 2014. The data were extracted from medical records to …

Predictors Of Health-Related Quality Of Life In Adult Hemophiliapatients In Cipto Mangunkusumo Hospital, Findy Prasetyawaty, Lugyanti Sukrisman, Bambang Setyohadi

Jurnal Penyakit Dalam Indonesia

Introduction. Currently, one of the main focus of hemophilia treatment is to increase health-related quality of life. Due to financial constraints, factor VIII substitution is used only on demand in Indonesia, which might contribute to musculoskeletal complications and affect the quality of life of adult hemophilia patients. This study aimed to evaluate quality of life of adult hemophilic patients and its related factors. Methods. A cross-sectional study on hemophilia patients aged 18 years or older was conducted at the Hematology-Medical Oncology outpatient clinic, Cipto Mangunkusumo Hospital Jakarta from March to May 2012. The radiologic assessment for arthropathy used the Arnold-Hilgartner …

Diagnostic Approach And Treatment Of Instestinal Tuberculosis, Artati Murwaningrum, Murdani Abdullah, Dadang Makmun

Jurnal Penyakit Dalam Indonesia

Tuberculosis (TB) has become a resurgent global problem with increasing numbers of patients. TB infection is still common and remains an important cause of morbidity and mortality, particularly in underdeveloped and developing nations. Intestinal tuberculosis (intestinal TB) rates are rising, consistet with the overall trend. In 2014 Indonesia has the second highest TB prevalence in South East Asia after Timor Leste. Intestinal TB is the sixth highest manifestation of extrapulmonal TB. Manifestations can be non-specific and mimic many conditions, including malignancies causes’ intestinal TB diagnosis more difficult to be accurately determined. Findings from endoscopy and radiological imaging are countless, and …

Hiperimunoglobulin E, Atopi Dan Hiv, Evy Yunihastuti

Jurnal Penyakit Dalam Indonesia

No abstract provided.