Medical Specialties Commons^™

Sars-Cov-2 Infection Complicated By Acute Pericarditis Concurrent With Malaria Infection, Kevin Hocin, Yudha Kusuma, Atit Puspitasari Dewi

Jurnal Penyakit Dalam Indonesia

Coronavirus disease 19 (COVID-19) can present as various symptoms, which range from asymptomatic to severe symptoms. We report a case of COVID-19 female patient with malaria co-infection who developed pericarditis complication. In this pandemic era, it is mandatory to rule out COVID-19. Coinfection with malaria will result in higher cytokine levels which lead to atypical complication, such as pericarditis. Prompt identification of atypical COVID-19 complications is essential as it can lower the mortality rate and reduce the duration of hospitalization.

Update In Laboratory Diagnosis Of Urinary Tract Infection, Weny Rinawati, Diana Aulia

Jurnal Penyakit Dalam Indonesia

Urinary tract infection (UTI) is an infection caused by the entry of pathogens into the urinary tract. Symptoms of a UTI are not always obvious, and some are asymptomatic or atypical. Urinary tract infections must be distinguished from other diseases that have a similar clinical appearance. Many UTIs resolve spontaneously, but often cause significant morbidity and mortality. With the unpredictable nature of the disease, laboratory tests are required for accurate diagnosis and identification of the cause of infection. Thus, it is necessary to understand the interpretation and limitations of urinalysis and urine culture results. To assist in the diagnosis of …

Comparison Of Hospital Mortality, Length Of Stay, Renal Recovery, And Needs For Hemodialysis In Acute Kidney Injury (Aki) Patients Due To Septic And Non-Septic, And Factors Affecting Patients’ Mortality, Mochammad Jalalul Marzuki, Nursamsu Nursamsu, Achmad Rifai

Jurnal Penyakit Dalam Indonesia

Introduction. Acute kidney injury (AKI) is a major complication in critically ill patients that affects mortality. Sepsis is a major predisposing factor for AKI and provides a poor prognosis and high mortality rate. Thisstudy aimed toidentifythe difference of hospital mortality, length of stay, renal recovery, and needs for hemodialysis between AKI patients due to sepsis and non-sepsis, as well as to determine the factors that influence the mortality of patients with AKI.Methods. An analytical observational study was conducted among patients with AKI according to the KDIGO criteria and aged ≥40 years old. Data were obtained from patients’ medical records in …

Characteristics Of Patients With Non-Malignant Pleural Effusion In Dr. Zainoel Abidin Hospital Banda Aceh In 2019, Teuku Romi Imansyah Putra, Price Maya, Maryatun Hasan, Agung Pranata, Safira Salsabila, Hesti Ariandani Sariningrum

Jurnal Penyakit Dalam Indonesia

Introduction. Pleural effusion occurs when there is a pathological process causing fluid to accumulate in the pleural cavity. Pleural effusion is still the main cause of respiratory distress and can also be caused by many diseases either from pleural, lungs, or even extrapulmonary problems. The morbidity and mortality of this condition are directly associated with the underlying causes. The aim of this study is to investigate the profile of the patients, etiology, location, fluid characteristics, comorbidities, and also the bacteria pattern of non-malignant pleural effusion. Methods. This is a retrospective descriptive study thatused patient’s medical records from January to December …

Kidney Disease And Its Impact On Covid-19 Patients At Sanglah Hospital Denpasar, Bali, Indonesia In 2021, Putu Satyakumara Upadhana, I Gede Gita Sastrawan Sastrawan, I Gusti Agung Ayu Chintya Cahyarini, Anbiya Khairul Umam, Amanda Trisliana Dwi Putri, I Gede Raka Adhyatma, I Ketut Agus Somia

Jurnal Penyakit Dalam Indonesia

Introduction. Besides having an impact on the respiratory system, COVID-19 also has an impact on other organ such as the kidneys. The systemic inflammatory response thought to be associated with bad prognosis of COVID-19 patients with kidney disease. This study aimed to determine the impact of kidney disease on COVID-19 patients. Methods. This study is an observational analytic study with a cross-sectional approach. The data used is secondary data from the records of confirmed COVID-19 patients who were treated at Sanglah Hospital from 1 May 2021 to 31 August 2021 using total sampling technique.Results. There were 248 patients included in …

Abnormal Liver Function In Predicting Covid-19 Patients’ Prognosis, Sakinah Rahma Sari, Juferdy Kurniawan

Jurnal Penyakit Dalam Indonesia

Despite of the high prevalence of liver enzyme elevation in COVID-19 patients, its effect on predicting COVID-19 patients’ prognosis was still debatable. This evidence-based case report aims to evaluate the effect of abnormal liver function in the prognosis of COVID-19 patients. Literature searching was performed on August 16-17 2021 using 3 databases: PubMed, Scopus, and Proquest. The articles selected by title/abstract screening, duplication elimination, and applying eligibility criteria were then appraised using Centre of Evidence Based Medicine (CEBM), University of Oxford. Some of the studies reported there were no significant difference in the prognosis of COVID-19 patient with and without …

Mutation And Variant Of Coronavirus Disease 2019 (Covid-19): Review Of Current Literatures, Adityo Susilo, Chyntia Olivia Maurine Jasirwan, Syahidatul Wafa, Suzy Maria, Wulyo Rajabto, Akhmadu Muradi, Ihza Fachriza, Myranda Zahrah Putri, Stacy Gabriella

Jurnal Penyakit Dalam Indonesia

Since March 2020, the Coronavirus Disease 2019 (COVID-19) pandemic has engulfed the world, including Indonesia, for nearly two years. SARS-CoV-2 has undergone several mutations during its evolution as a pathogen, resulting in various variants of global concern. Variants of this virus are suspected to impede the outbreak resolution and possibly causing the outbreak to spiral out of control. There is still considerable debate and research underway regarding the new SARS-CoV-2 variants. Rapid transmission mechanisms and widespread vaccination coverage have accelerated the virus’s mutation rate and resulted in numerous new variants. To date, this has resulted in the discovery of a …

The Prevalence Of Irritable Bowel Syndrome Using Rome Iv Criteria In Medical Student And The Related Factors, Ardhi Rahman Ahani, Ari Fahrial Syam, Rudi Putranto, Pringgodigdo Nugroho

Jurnal Penyakit Dalam Indonesia

Introduction. Medicine is a long study time. Medical student will take five years study to accomplish the education. Because the lot of task and some taken test, some medical student will face irritable bowel syndrome in their study periods. This study aims to identify the prevalence of IBS in medical student and related factors.Methods. A cross-sectional study of 350 medical student Universitas Indonesia from first grade until fifth grade was done during November-December 2016. This study used stratified randomized sampling. The Rome IV criteria was used for diagnosing IBS. Interview with questionnaire guided was applied to all subjects. A bivariate …

Covid-19 Dari Perspektif Penyakit Ginjal : Dalam Rangka Memperingati Hari Ginjal Sedunia (World Kidney Day 2022), Anandhara Indriani Khumaedi

Jurnal Penyakit Dalam Indonesia

Secara global, hingga saat ini pandemi Coronavirus disease-19 (COVID-19) telah menjangkit lebih dari 450 juta orang di dunia dan menyumbang kematian sebanyak 6 juta jiwa.

Prediction Model Of 30-Days Postoperative Pneumonia In Elderly Patient Undergoing Abdominal Surgery, Noto Dwimartutie, Harini Oktadiana, Gurmeet Singh, Wifanto Saditya Jeo, Kuntjoro Harimurti

Jurnal Penyakit Dalam Indonesia

Introduction. Physiologic changes in respiratory tract in elderly increase incidence of post-operative pneumonia. Post-operative pneumonia in non-thoracic surgery was found higher in abdominal surgery. This study aimed to develop a prediction model of 30-day post-operative pneumonia in elderly patients undergoing abdominal surgery.

Methods. A retrospective cohort study was conducted using elderly patient’s medical records who underwent abdominal surgery in Cipto Mangunkusumo General Hospital. Multivariate analysis using logistic regression was used to determine Odds Ratio (OR). Model’s calibration performance was determined by Hosmer-Lameshow test and its discrimination performance was determined by calculating area under the curve (AUC).

Results. Of …

Pain Management In Advanced Hepatocellular Carcinoma:A Case Study, Fita Fitrianti, Hamzah Shatri, Edward Faisal, Rud Putranto, Ratih Arianita Agung, Leonard Nainggolan, Kemal Fariz Kalista, Cophiadi Irawan

Jurnal Penyakit Dalam Indonesia

Hepatocelullar carcinoma (HCC), the most common primary liver malignancy is the fifth most common cancer and the third most frequent cause of cancer related death globally. Pain comprises one the most common symptoms of HCC and may have severely negative effects on patient’s quality life. Furthermore, patients with HCC often presented with a cirrochis,so to control pain in this patient poses a clinical challenge. This case report discuss about a young 26-years-old male patient who presented with a four-month history of right upper quadrant abdominal pain and weight loss. HbsAg positive and serum alpha-fetoprotein level was high. Computed tomography (CT) …

The Difference In Nutrition Intake Adequacy Amonginstitutionalized Elderly Residents With And Without Sarcopeniaat Nursing Homes In Bandung, West Java, Delia Anastasia Tirtadjaja, Muhamad Apandi, Lazuardhi Dwipa

Jurnal Penyakit Dalam Indonesia

Introduction. The changes in the elderly’s daily routine including dietary intake and nutritional pattern may cause them to be more susceptible to malnutrition. The changes also increase the risk of sarcopenia that may lead to poor health outcomes such as fall injury, fracture, hospitalization, disability, or even death. Sarcopenia is more likely to occur in a nursing home compared to community settings. This study aimed to determine the difference in nutrition intake adequacy between institutionalized elderly subjects with and without sarcopenia in Bandung, West Java. Methods. A cross-sectional study was held in Ciparay and Budi Istri Nursing Home, Bandung, West …

Factors Associated With Length Of Stay Of Covid-19 Patients At Serui Regional General Hospital Papua Province: Cross-Sectional Study, Fahri Ahmad Baihaqi, Henny Rumaropen

Jurnal Penyakit Dalam Indonesia

Introduction. Coronavirus Disease 2019 (COVID-19) is a respiratory infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 has become a global health problem. The length of stay of the patient is related to the use of hospital resources. COVID-19 patients are at risk of increasing length of stay due to various factors and the increased length of stay can increase the burden of health services. The purpose of this study was to determine the factors that influence the length of stay of COVID-19 patients.Methods. An observational analytic study with a cross-sectional design was conducted at Serui Regional General …

The Relationship Of Subjective Global Assessment (Sga) With Energy Intake, Protein, Hand Grip Strength And Body Mass Index In Chronic Kidney Disease (Ckd) Patients With Continuous Ambulatory Peritoneal Dialysis (Capd), Yudhi Adrianto, Ni Made Hustrini, Triyani Kresnawan, Annisa Eka Amelia, Fitri Hudayani

Jurnal Penyakit Dalam Indonesia

Introduction. Energy and protein intake in chronic kidney disease (CKD) with continuous ambulatory peritoneal dialysis (CAPD) therapy plays an important role in balancing hypercatabolic conditions. Unbalanced intake will result in energy and protein deficits which are increasing the risk of muscle catabolism, decreasing body mass index (BMI), and malnutrition. Subjective global assessment (SGA) as the gold standard in nutritional assessment is needed in assessing nutritional status and determining malnutrition, therefore nutritional intervention can be delivered and improve CAPD patients’ quality of life. This study was conducted to determine the relationship between SGA with energy and protein intake, hand grip strength, …

Correlation Between Polypharmacy And Length Of Stay Geriatric Patient In Mohammad Hoesin Palembang Hospital, Iswadi Tanzil, Nur Riviati, Irsan Saleh

Jurnal Penyakit Dalam Indonesia

Introduction. Geriatric patients have multipathological characteristics, low physiologic reserves, atypical clinical signs and symptoms, decreased functional status, and nutritional disturbances. This situation is a risk factor for polypharmacy. Polypharmacy is closely related to drug side effects, drug interactions, and patient compliance. Polypharmacy is thought to have a relationship with the length of stay in geriatric patients. The purpose of this study was to determine the correlation between polypharmacy and length of stay in geriatric patients at Moehammad Hoesin Hospital Palembang. Methods. This was a cross-sectional study with a correlation test design conducted at Dr. Mohammad Hoesin Hospital (RSMH) Palembang from …

Depresi Pada Populasi Lanjut Usia Yang Menjalani Hemodialisis, Edward Faisal

Jurnal Penyakit Dalam Indonesia

Menurut laporan tahunan European Renal Association–European Dialysis and Transplant Association (ERA-EDTA), pasien yang menjalani transplantasi ginjal dari tahun 2014 sampai 2018 memiliki kesempatan hidup hanya setengah dari usia dengan sisa fungsi ginjal yang ditransplantasikan, sedangkan untuk pasien yang dilakukan hemodialisis (HD) adalah 70% lebih pendek.

Management Of Chronic Kidney Disease-Mineral And Bone Disorder (Ckd-Mbd), Pringgodigdo Nugroho

Jurnal Penyakit Dalam Indonesia

Chronic kidney disease (CKD) is still a burden on worldwide health issues affecting about 11-13% of the general population. Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a common complication in CKD, which occurs early in the disease, and progresses as kidney function deteriorates. With declining kidney function, mineral homeostasis becomes progressively dysregulated, including alterations in several parameters such as calcium, phosphate, intact parathyroid hormone (iPTH). Changes in these parameters are associated with bone disorders and vascular abnormalities, which are strongly correlated with increased cardiovascular (CV) morbidity and mortality, and overall mortality. Currently, CKD-MBD and its complication management have been …

Comparison Of Lipid Profiles In Patients With Type 2 Diabetes Mellitus With Good Glycemic Control And Poor Glycemic Control In Rsud Dr. Saiful Anwar Malang, Nyoman Satvika Dharma Yudha, Putu Moda Arsana, Rulli Rosandi

Jurnal Penyakit Dalam Indonesia

Introduction. Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia due to insulin resistance, deficiency of insulin action, or both with a prevalence of 8.5% in Indonesia. Evidence regarding the relationship between HbA1c and lipid profile in type 2 DM is currently contradictory, therefore a study was conducted to examine the relationship between glycemic control and lipid profile for DM patients.Methods. This survey research was conducted at the outpatient endocrine clinic Dr. Saiful Anwar Malang Hospital in 2014-2019 with a total of 1,308 patients. Patients were then classified into type 2 DM patients with good (HbA1c < 7%, n = 291) and poor glycemic control (HbA1c > 7%, …

Depressive Symptoms As A Predictor Factor Of All-Cause Mortality Within Six Months In Elderly Hemodialysis Patients, Langgeng Perdhana, Shofa Chasan, Yudo Murti Mupangati, Siti Nuraini

Jurnal Penyakit Dalam Indonesia

Introduction. Depression is a mental disorder that is often found in the elderly and hemodialysis patients, resulting in bad effects on patients. There is no study on the relationship between depression and all-cause mortality risk in elderly hemodialysis patients in Indonesia. This study aimed to determine the role of depression as a predictor factor of all-cause mortality within 6 months in elderly hemodialysis patients. Methods. A prospective cohort study was conducted from February to August 2020 at the hemodialysis unit of Roemani Muhammadiyah Hospital, Semarang. The inclusion criteria were elderly patients (aged ≥60 years), undergoing hemodialysis ≥3 months, hemodialysis frequency …

The Challenges Of Diagnosis And Management Of Suspectedautoimmune Hepatitis In A 34-Year-Old Woman With Periodicparalysis And Graves’ Disease, Yeni Larasati, C. Singgih Wahono

Jurnal Penyakit Dalam Indonesia

Periodic paralysis hypokalemia is a muscle weakness that can be caused by hyperthyroidism due to Graves’ disease. The prevalence reaches 10% of patients with periodic paralysis hypokalemia with symptoms of thyrotoxicosis. Graves’ disease is an immune system disorder that can cause other organ dysfunction, such as autoimmune hepatitis. Currently, the diagnosis of autoimmune hepatitis is still a challenge for clinicians due to limited supporting examination facilities, such as SMA, AMA, anti-LKM-1. This article discusses a case of a 34-year-old woman with limb weakness for 3 months, losing 4 kg of weight in 1 month, often feeling hungry, restless, having trouble …

In-Hospital Mortality Risk Factors Among Hospitalized Geriatric Patients: A Cohort Study On Tertiary Referral Hospital In Indonesia, Fadhil Abiyyu Yofi, Arlia Ayu Damayanti, Novira Widajanti

Jurnal Penyakit Dalam Indonesia

Introduction. Decreasing fertility rates and increasing life expectancy cause an increase in the population of the elderly, with the number of elderly in the world is estimated to increase from 9.3% in 2020 to 16.0% in 2050. 24.35% of the elderly in Indonesia experience illness, and 8.71% have been hospitalized in one year. This study aimed to determine the risk factors for the death of elderly who were hospitalized.

The Role Of Albumin And Hemoglobin As Predictors Of 28-Day Mortality In Elderly Sepsis Patients In Mohammad Hoesin Hospital Palembang, Widya Mandala Sari Gultom, Nur Riviati, Rizky Perdana, Syarif Husin

Jurnal Penyakit Dalam Indonesia

Introduction. Sepsis is defined as organ dysfunction caused by dysregulation of the host’s response to infection. The majority of sepsis are experienced by elderly patients with high mortality rates. In the condition of sepsis, there are various body mechanisms that cause a decrease in albumin and hemoglobin. This study is to determine the predictive value of albumin and hemoglobin levels on 28-day mortality of elderly sepsis patients.

Nucleoside/Nucleotide Analogues For The Treatment Of Chronic Hepatitis B: A 3-Year Follow Up Study, Andri Sanityoso Sulaiman, Irsan Hasan, Cosmas Rinaldi A Lesmana, Chyntia Olivia M Jasirwan, Saut Horas H. Nababan, Kemal Fariz Kalista, Gita Aprilicia, Rino Alvani Gani

Jurnal Penyakit Dalam Indonesia

Introduction. Chronic hepatitis B (CHB) is endemic in Indonesia, where it is usually treated with pegylated interferon and nucleoside/nucleotide analogs (NA). The aim of this study was to determine the efficacy of treating CHB infection among Indonesian patients with NA (lamivudine, telbivudine, and tenofovir) for a 3-year period.Methods. We retrospectively reviewed the records of patients with CHB infection attending the Hepatology Clinic Cipto Mangunkusumo during 2010-2013 period. Subjects with inclusion criteria were all patients aged above 18 years treated with NA for at least three years. The degree of liver stiffness, hepatitis B virus deoxyribonucleic acid (HBV-DNA), alanine aminotransferase (ALT) …

Neutrophil Lymphocyte Ratio, Three Year Survival Of Locally Advanced And Advanced Nasopharyngeal Carcinoma, Rahmat Cahyanur, Hayatun Nufus, Cosphiadi Irawan

Jurnal Penyakit Dalam Indonesia

Introduction. Nasopharyngeal carcinoma (NPC) is the most prevalent head and neck malignancy in Indonesia, as NPC-related mortality in Indonesia is the second-highest in Asia after China. Inflammation has been studied to be associated with cancer progression. Neutrophil lymphocyte ratio describes the balance between the unfavorable suppression of immune response against cancer by neutrophils and the beneficial effect of adaptive immunity by lymphocytes. This study aimed to determine the relationship between NLR and the survival of locally advanced and advanced NPC patients.Methods. A retrospective cohort study was conducted using the medical records of NPC patients treated at the hematology clinic RSCM …

Perkembangan Terapi Hepatitis B Kronis Di Indonesia, Juferdy Kurniawan

Jurnal Penyakit Dalam Indonesia

Indonesia merupakan salah satu negara dengan prevalensi hepatitis B yang tinggi di Asia Tenggara (kedua setelah Vietnam). Berdasarkan Riskesdas yang dilakukan oleh Kementerian Kesehatan Republik Indonesia, pada studi yang dilakukan pada sampel darah PMI, 10 dari 100 orang Indonesia terinfeksi hepatitis B atau C. Maka dari itu, dibutuhkan penanganan yang ekstra untuk penanggulangan masalah infeksi hepatitis B

Cutaneous Anthrax In Gunung Kidul, Yogyakarta: A Case Report, Riswanto Riswanto, Dhani Redhono, Evi Nurhayatun

Jurnal Penyakit Dalam Indonesia

Bacillus anthracis is an aerobic, gram-positive, and spore-forming Bacillus species. The most common form of anthrax infection is the cutaneous form. The infection usually develops several days after exposure to products of infected animals and manifest as a black sore with severe swelling on the skin. In this report, a 60-year-old man with a black and swollen lesion on her index finger presented in Gunung Kidul in December 2019. ELISA antibody anthrax serum was performed. The patient was then treated with antibiotics after diagnosis. This patient had a history of contact with the beef of a slaughtered sheep. The patient …

Predictors Of Handgrip Strength Changes In Elderly Patients, Ummi Ulfah Madina, Siti Setiati, Purwita Wijaya Laksmi, Arif Mansjoer

Jurnal Penyakit Dalam Indonesia

Introduction. The increasing elderly population throughout the world has been related to the increased prevalence of sarcopenia and frailty. Handgrip strength is a component of sarcopenia, one of frailty syndrome phenotypes. Previous studies have assessed the association of age, sex, nutritional status, functional status, mental status, and comorbidity, but varied results. No longitudinal study has been done to determine the correlation of handgrip strength changes with age, sex, nutritional status, functional status, mental status, and comorbidity in Indonesia. The aim of this study was to determine the correlation between age, sex, nutritional status, functional status, depressive symptoms, comorbidity, and handgrip …

The Influence Of Characteristics And Behavior On The Incidence Of Pulmonary Tuberclosis In Al-Hidayah Pesantren, Kejuruan Muda Subdistric Tamiang District, Aceh Province, 2019, Indah Anggraini, Basaria Hutabarat

Jurnal Penyakit Dalam Indonesia

Introduction. Pulmonary tuberculosis is a chronic infectious disease that is a global issue. Some factors influence the occurrence of pulmonary tuberculosis, among others, the source of infection, a high amount of virulence bacilli, and decreased endurance. This study aims to determine the effect of characteristics and behavior on the incidence of pulmonary TB disease in Al-Hidayah Islamic Boarding School, Vocational School, Aceh Tamiang Regency. Method. This research is analytic with a cross-sectional research design. Data analysis uses Chi-Square test and Logistic Regression) to determine the influence of the most dominant risk factors with pulmonary TB disease incidence. Results. The results …

Depression In Heart Failure: Psychosomatic Approachv, Rudi Putranto, Hamzah Shatri, Ika Prasetya Wijaya, Edward Faisal

Jurnal Penyakit Dalam Indonesia

Depression is a common condition in heart failure (HF) and is considered a risk factor for cardiovascular disease. Depression disorder in patients with heart disease paradigmatically defines a psychosomatic-somatopsychic challenge to any health delivery. However, despite the devastating effects of depression, it is often underdiagnosed and receives little attention in heart failure patients. This review provides an extensive overview of HF regarding epidemiology, disease pathophysiology, diagnosis, and management from the latest literature. Based on the literature review, the prevalence of depression in heart failure in Indonesian patients was 5.3-42%. Psychological stress experienced by people suffering from depression can cause dysregulation …

Non-Operative Management Of Diabetic Foot Osteomyelitis: Acase Report, Em Yunir, Yully Astika Nugrahayning Aziza

Jurnal Penyakit Dalam Indonesia

Diabetic foot osteomyelitis is an advanced complication of diabetic foot infection which can increase the risk of amputation. This report discusses a case of a 50-year-old female with a wound on the thumb of her left foot that became more swollen with a bluish red color within one month. The patient delayed her treatment due to the COVID-19 pandemic. She has had diabetes and hypertension for 20 years which is uncontrolled. Physical examination showed a sausage toe digiti 1 left pedis with wound 4 x 2 cm with purulent discharge, Probe to Bone (PTB) positive. Laboratory and x-ray examination showed …