Medical Specialties Commons^™

A Low Fidelity Eye Model For Lateral Canthotomy Training, R. Kong, D. P. Kaya, E. Cioe-Pena, J. Greenstein

Journal Articles

© 2018 African Federation for Emergency Medicine We introduce a low-fidelity, low-cost, reusable training model for the lateral canthotomy procedure. We believe that this trainer has the potential to improve clinicians’ knowledge and skill of the procedure, especially when cost or access to higher-fidelity trainers is prohibitive.

Child With Testicular Pain., N. Otts, R. L. Webb, J. Greenstein, B. Hahn

Journal Articles

No abstract provided.

A Novel Approach To Addressing An Unintended Consequence Of Direct To Room: The Delay Of Initial Vital Signs., J. Basile, E. Youssef, B. Cambria, J. Chacko, K. Treval, B. Hahn, B. Ardolic

Journal Articles

Introduction: The concept of "direct to room" (DTR) and "immediate bedding" has been described in the literature as a mechanism to improve front-end, emergency department (ED) processing. The process allows for an expedited clinician-patient encounter. An unintended consequence of DTR was a time delay in obtaining the initial set of vital signs upon patient arrival.

Methods: This retrospective cohort study was conducted at a single, academic, tertiary-care facility with an annual census of 94,000 patient visits. Inclusion criteria were all patients who entered the ED from 11/1/15 to 5/1/16 and between the hours of 7 am to 11 pm. During …

Arthroscopic Knotless Rotator Cuff Repair: Factors Associated With Construct Selection And Recent Trends From A Manual Review Of 1617 Cases, S. S. Shah, A. Shah, V. Chadayammuri, M. Mcgill, N. Wei, D. V. Tuckman, N. A. Sgaglione

Journal Articles

© 2018 Prof. PK Surendran Memorial Education Foundation Purpose: Our aim was to identify predictors of construct selection and recent trends for arthroscopic knotless rotator cuff repair (RCR). Methods: A manual review of 1617 operative reports was performed. Results: A medium-sized tear had a threefold increase in odds of single row (SR) knotless repair (OR, 6.91; p = 0.009) versus SR knotted (OR, 3.05; p = 0.003). Generalist orthopaedic surgeons were 79% less likely to perform SR knotless repairs versus sports medicine trained specialists (p < 0.001). Conclusion: There was a significant increase from 2009 to 2016 in SR knotless and double row medial row knotless constructs contrasting the declining use of the SR knotted technique.

Can Weakness In End-Range Plantar Flexion After Achilles Tendon Repair Be Prevented?, K. F. Orishimo, S. Schwartz-Balle, T. F. Tyler, M. P. Mchugh, B. B. Bedford, S. J. Lee, S. J. Nicholas

Journal Articles

Background: Disproportionate end-range plantar flexion weakness, decreased passive stiffness, and inability to perform a heel rise on a decline after Achilles tendon repair are thought to reflect increased tendon compliance or tendon lengthening. Since this was first noted, we have performed stronger repairs and avoided stretching into dorsiflexion for the first 12 weeks after surgery.

Hypothesis: Using stronger repairs and avoiding stretching into dorsiflexion would eliminate end-range plantar flexion weakness and normalize passive stiffness.

Study Design: Case series; Level of evidence, 4.

Methods: Achilles repairs with epitendinous augmentation were performed on 18 patients. Plantar flexion torque, dorsiflexion range of motion …

Compartment Syndrome Of The Hand: A Case Report And Review Of Literature, V. Mehta, V. Chowdhary, C. Lin, M. Jbara, S. Hanna

Journal Articles

© 2017 The Authors Elevation of pressure within tightly bound myofascial compartments has detrimental consequences if not treated promptly, leading to a loss of circulation, ischemia, myonecrosis, nerve damage, and limb loss. They are commonly seen in the distal upper and lower extremities; however, compartment syndrome of the hand is rarely encountered and prompt recognition can prevent permanent damage and tissue loss. This case study presents a complicated case of compartment syndrome of the hand and discusses the interrelationship between compartment syndrome and rhabdomyolysis. An emphasis is placed on pathophysiology of this relationship to allow a better understanding of the …

Interpreting 123i-Ioflupane Dopamine Transporter Scans Using Hybrid Scores., K. J. Nichols, B. Chen, M. B. Tomas, C. J. Palestro

Journal Articles

Dopamine transporter (DaT) 123I-FP-CIT scans most commonly are interpreted visually. Alternatively, absolute quantitation of radiopharmaceutical uptake may improve scan accuracy. However, neither approach accomodates dependence of striatal uptake on age and gender. We investigated whether demographic indexing of visual and numerical variables improve discrimination of patients with essential tremor (ET), Parkinson's disease (PD), and dementia with Lewy bodies (DLB).Data of 132 consecutive patients undergoing DaT SPECT scans were reviewed retrospectively. The clinical impression in the latest neurology note was utilized as the final clinical diagnosis. Caudate and putamen specific binding ratio (PSBR) were computed. 123I calibration phantoms were constructed to …

Acute Pulmonary Embolism: Endovascular Therapy, S. P. Reis, K. Zhao, N. Ahmad, R. S. Widemon, C. W. Root, S. M. Toomay, J. M. Horowitz, A. K. Sista

Journal Articles

© Cardiovascular Diagnosis and Therapy. All rights reserved. Pulmonary embolism (PE) is a leading cause of morbidity and mortality worldwide. PE is a complex disease with a highly variable presentation and the available treatment options for PE are expanding rapidly. Anticoagulation (AC), systemic lysis, surgery, and catheter-directed thrombolysis (CDT) play important roles in treating patients with PE. Thus, a multidisciplinary approach to diagnosis, risk stratification, and therapy is required to determine which treatment option is best for a given patient with this complex disease.

Congenital Rhabdomyosarcoma Presenting As A Neck Mass At Birth., L. E. Waldman, A. K. Williamson, J. B. Amodio, L. Collins

Journal Articles

Rhabdomyosarcoma is a malignant tumor of the soft tissues which preferentially affects the pediatric population. Neonatal rhabdomyosarcoma is rare, and much of the published literature concerning this entity consists of isolated case reports and small case series. Recent work involving the classification of rhabdomyosarcoma has helped to delineate prognostic information based on gene rearrangements. Here, we present a case of congenital rhabdomyosarcoma seen in utero which manifested as a neck mass at birth and was found to harbor a favorable gene fusion.

Transrenal Ureteral Embolization Utilizing Amplatzer Vascular Plugs And N-Butyl Cyanoacrylate Glue., M. X. Jin, A. D. Mohabir, D. M. Caplin, I. Lobko, D. N. Siegel

Journal Articles

This retrospective study presents three consecutive patients who underwent bilateral ureteral occlusion using the Amplatzer vascular plugs and N-butyl cyanoacrylate glue sandwich method. The patients were 63- and 65-year-old males and a 79-year-old female. Indications for the procedure included severe cystitis and complex vesicular fistulas unresponsive to urinary diversion. All three patients had immediate resolution of urinary leakage, resulting in symptom relief throughout the follow-up period. There were no procedure-related complications or side effects.

Sports Hernia/Athletic Pubalgia Among Women, M. P. Zoland, J. C. Iraci, S. Bharam, L. E. Waldman, J. P. Koulotouros, D. Klein

Journal Articles

© The Author(s) 2018. Background: “Athletic pubalgia,” a term that has gained acceptance over “sports hernia,” is more common in men than women; however, it represents a significant source of morbidity for patients of both sexes. Inconsistent terminology surrounding this entity poses a diagnostic challenge and makes studying the populations at risk difficult. Purpose: To review a case series of women with athletic pubalgia by analyzing their presentations, concomitant pathologies, and surgical outcomes. Study Design: Case series; Level of evidence, 4. Methods: Between 2013 and 2016, 197 patients were seen and evaluated for the diagnosis of athletic pubalgia. Eighteen patients …

A Case Of Primary Squamous Cell Carcinoma Of The Gallbladder With Local Invasion Of The Liver And Peritoneum, And Metastasis To The Omentum., A. C.J. Levy, F. Casalduc-Coca, S. Asiry, A. Goodman

Journal Articles

Primary squamous cell carcinoma of the gallbladder is a rare entity that comprises approximately 1%-3% of all primary gallbladder cancers. We report the case of a 37-year-old woman who was diagnosed with a locally invasive squamous cell carcinoma of the gallbladder. Surgical pathology revealed a predominantly squamous cell carcinoma composition of the tumor with a few microscopic foci of adenocarcinoma (

Dynamic Functional Connectivity States Reflecting Psychotic-Like Experiences, A. D. Barber, M. A. Lindquist, P. Derosse, K. H. Karlsgodt

Journal Articles

© 2017 Society of Biological Psychiatry Background: Psychotic-like experiences (PLEs) are associated with lower social and occupational functioning, and lower executive function. Emerging evidence also suggests that PLEs reflect neural dysfunction resembling that of psychotic disorders. Methods: The present study examined dynamic connectivity related to a measure of PLEs derived from the Achenbach Adult Self-Report, in an otherwise-healthy sample of adults from the Human Connectome Project. A total of 76 PLE-endorsing and 153 control participants were included in the final sample. To characterize network dysfunction, dynamic connectivity states were examined across large-scale resting-state networks using dynamic conditional correlation and k-means …

Functional Activation During A Cognitive Control Task In Healthy Youth Specific To Externalizing Or Internalizing Behaviors, K. H. Karlsgodt, A. A. Bato, T. Ikuta, B. D. Peters, P. Derosse, P. R. Szeszko, A. K. Malhotra

Journal Articles

© 2017 Society of Biological Psychiatry Background: Externalizing behaviors are negative behaviors expressed outwardly, including rule breaking, aggression, and risk taking; internalizing behaviors are expressed inwardly, including depression, withdrawal, and anxiety. Such behavior can cause problems in early life and predict difficulties across the lifespan. There is evidence for a relationship between executive function and both externalizing and internalizing. However, although these behaviors occur along a spectrum, there is little neuroimaging research on this relationship in typically developing youth. Methods: We assessed 41 youth (10–19 years of age) using the Multi-Source Interference Task during functional magnetic resonance imaging and related …

Management Of Acute Pancreatitis In The Pediatric Population: A Clinical Report From The North American Society For Pediatric Gastroenterology, Hepatology And Nutrition Pancreas Committee, M. Abu-El-Haija, S. Kumar, J. A. Quiros, K. Balakrishnan, B. Barth, S. Bitton, J. F. Eisses, E. J. Foglio, V. Fox, V. D. Morinville, +14 Additional Authors

Journal Articles

No abstract provided.

Microarray Analysis Of Human Keratinocytes From Different Anatomic Sites Reveals Site-Specific Immune Signaling And Responses To Human Papillomavirus Type 16 Transfection, M. Israr, D. Rosenthal, L. Frejo-Navarro, J. Devoti, C. Meyers, V. R. Bonagura

Journal Articles

No abstract provided.

Delays To Care In Pediatric Lupus Patients: Data From The Childhood Arthritis And Rheumatology Research Alliance Legacy Registry., Tamar B Rubinstein, Wenzhu B Mowrey, Norman T Ilowite, Dawn M Wahezi, L. Abramson, E. Anderson, M. Andrew, N. Battle, J. Chang, B. Gottlieb, +90 Additional Authors

Journal Articles

OBJECTIVE: Prompt treatment for lupus is important to prevent morbidity. A potential barrier to early treatment of pediatric lupus is delayed presentation to a pediatric rheumatologist. To better understand factors contributing to delayed presentation among pediatric lupus patients, we examined differences in demographic and clinical characteristics of lupus patients within the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry with regard to time between symptom onset and presentation to a pediatric rheumatologist.

METHODS: We analyzed data from 598 CARRA Legacy Registry participants for differences between those who presented early (withinonset), between 1-3 months (typical presentation), with moderate delays (3-12 …

Psychopharmacological Treatment In The Raise-Etp Study: Outcomes Of A Manual And Computer Decision Support System Based Intervention, D. G. Robinson, N. R. Schooler, C. U. Correll, M. John, B. T. Kurian, P. Marcy, A. L. Miller, R. Pipes, M. H. Trivedi, J. M. Kane

Journal Articles

No abstract provided.

Exploration Of Treatment Matching Of Problem Drinker Characteristics To Motivational Interviewing And Non-Directive Client-Centered Psychotherapy, A. Kuerbis, J. Houser, S. Levak, S. Shao, J. Morgenstern

Journal Articles

No abstract provided.

Digital Peer-Support Platform (7cups) As An Adjunct Treatment For Women With Postpartum Depression: Feasibility, Acceptability, And Preliminary Efficacy Study, A. Baumel, A. Tinkelman, N. Mathur, J. M. Kane

Journal Articles

No abstract provided.

A Simulations Approach For Meta-Analysis Of Genetic Association Studies Based On Additive Genetic Model, M. John, T. Lencz, A. K. Malhotra, C. U. Correll, J. P. Zhang

Journal Articles

© 2018 Elsevier B.V. Meta-analysis of genetic association studies is being increasingly used to assess phenotypic differences between genotype groups. When the underlying genetic model is assumed to be dominant or recessive, assessing the phenotype differences based on summary statistics, reported for individual studies in a meta-analysis, is a valid strategy. However, when the genetic model is additive, a similar strategy based on summary statistics will lead to biased results. This fact about the additive model is one of the things that we establish in this paper, using simulations. The main goal of this paper is to present an alternate …

Comparing Daily Drivers Of Problem Drinking Among Older And Younger Adults: An Electronic Daily Diary Study Using Smartphones, A. Kuerbis, H. Treloar Padovano, S. Shao, J. Houser, F. J. Muench, J. Morgenstern

Journal Articles

© 2018 Elsevier B.V. Background: By 2030, numbers and proportions of older adults with substance-use problems are expected to increase. While risk factors for problem drinking in late life have been identified, it remains unknown whether these factors drive daily drinking among older problem drinkers. This study examined the daily drivers of drinking among problem drinkers, moderated by age, utilizing ecological momentary assessment (EMA). Method: Participants (N = 139), ages 20–73, received daily EMA online surveys completed via a smartphone prior to initiation of treatment. Multilevel modeling tested the moderating impact of age on within- and between-person relationships between drinking …

Dopamine Modulates Striatal Response To Reward And Punishment In Patients With Parkinson's Disease: A Pharmacological Challenge Fmri Study, M. Argyelan, M. Herzallah, W. Sako, I. Delucia, D. Sarpal, V. An, T. Fitzpatrick, A. A. Moustafa, D. Eidelberg, M. Gluck

Journal Articles

No abstract provided.

Dimensional Symptom Severity And Global Cognitive Function Predict Subjective Quality Of Life In Patients With Schizophrenia And Healthy Adults, P. Derosse, G. C. Nitzburg, M. Blair, A. K. Malhotra

Journal Articles

No abstract provided.

Study Of 300,486 Individuals Identifies 148 Independent Genetic Loci Influencing General Cognitive Function, G. Davies, M. Lam, S. E. Harris, J. W. Trampush, M. Luciano, P. Derosse, J. Yu, A. Malhotra, T. Lencz, I. J. Deary, +211 Additional Authors

Journal Articles

No abstract provided.

Association Between Psychosis In Elderly Patients With Alzheimer Disease And Impaired Social Cognition, J. Koppel, A. Sousa, M. L. Gordon, L. Giliberto, E. Christen, P. Davies

Journal Articles

No abstract provided.

Summary Of Key Issues Raised In The Technology For Early Awareness Of Addiction And Mental Illness (Teaam-I) Meeting, A. Baumel, J. Baker, M. L. Birnbaum, H. Christensen, M. De Choudhury, D. C. Mohr, F. Muench, D. Schlosser, N. Titov, J. M. Kane

Journal Articles

No abstract provided.

Computational Linguistic Analysis Applied To A Semantic Fluency Task To Measure Derailment And Tangentiality In Schizophrenia, L. Pauselli, B. Halpern, S. D. Cleary, B. Ku, M. A. Covington, M. T. Compton

Journal Articles

No abstract provided.

Genome-Wide Association Meta-Analysis In 269,867 Individuals Identifies New Genetic And Functional Links To Intelligence, J. E. Savage, P. R. Jansen, S. Stringer, K. Watanabe, J. W. Trampush, P. Derosse, T. Lencz, A. K. Malhotra, J. Yu, D. Posthuma, +107 Additional Authors

Journal Articles

No abstract provided.

The Age-Related Perfusion Pattern Measured With Arterial Spin Labeling Mri In Healthy Subjects, N. Zhang, M. L. Gordon, Y. Ma, B. Chi, J. J. Gomar, S. Peng, P. B. Kingsley, D. Eidelberg, T. E. Goldberg

Journal Articles

No abstract provided.