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Articles 91 - 120 of 2151
Full-Text Articles in Medical Specialties
Thrombolytic Therapy In Acute Myocardial Infarction: An Emergency Department Perspective, Bradford L. Walters
Thrombolytic Therapy In Acute Myocardial Infarction: An Emergency Department Perspective, Bradford L. Walters
Henry Ford Hospital Medical Journal
No abstract provided.
Lidocaine Prophylaxis In Acute Myocardial Infarction, James E. Tisdale
Lidocaine Prophylaxis In Acute Myocardial Infarction, James E. Tisdale
Henry Ford Hospital Medical Journal
The prophylactic administration of lidocaine for the prevention of primary ventricular fibrillation (VF) following suspected acute myocardial infarction (Ml) is controversial. The incidence of primary VF following acute Ml ranges from 1.8% to 10.5%. "Warning arrhythmias" have not been shown to be reliable predictors of VF. In-hospital prophylactic administration of lidocaine has been shown to decrease the incidence of primary VF. whereas prehospital administration has not. However, prophylactic administration of lidocaine has not been shown to have a beneficial effect on mortality and may in fact increase mortality. The incidence of lidocaine-induced adverse effects during prophylaxis ranges from 4% to …
Diagnosis And Management Of Tachycardias After Myocardial Infarction, Charles R. Webb
Diagnosis And Management Of Tachycardias After Myocardial Infarction, Charles R. Webb
Henry Ford Hospital Medical Journal
No abstract provided.
Role Of Coronary Angioplasty In Acute Myocardial Infarction, Susheel K. Sharma, Kenneth Retter, Fareed Khaja
Role Of Coronary Angioplasty In Acute Myocardial Infarction, Susheel K. Sharma, Kenneth Retter, Fareed Khaja
Henry Ford Hospital Medical Journal
No abstract provided.
Surgical Treatment Of Acute Myocardial Infarction, Arthur R. Dresdale, Gaetano Paone
Surgical Treatment Of Acute Myocardial Infarction, Arthur R. Dresdale, Gaetano Paone
Henry Ford Hospital Medical Journal
In recent years, advances in surgical techniques and perioperative management of cardiac surgical patients have facilitated more aggressive operative treatment of many serious and even catastrophic complications of acute myocardial infarction (Ml). In addition, improved understanding of the natural history of these complications has helped to optimize the indications for and timing of surgical intervention. The role of emergency revascularization for postinfarction angina, evolving acute MI, cardiogenic shock after acute MI, and failed percutaneous transluminal angioplasty has expanded with overall satisfactory to excellent results. Surgical treatment of mechanical complications of acute Ml such as free-wall rupture, acute ischemic mitral insufficiency, …
Caring For The Acute Myocardial Infarction Patient: A Nursing Perspective, Denise L. Crimaldi Adams, Sandra R. Perez
Caring For The Acute Myocardial Infarction Patient: A Nursing Perspective, Denise L. Crimaldi Adams, Sandra R. Perez
Henry Ford Hospital Medical Journal
Cardiac nursing is nearly 30 years old. Changes in the rote of cardiac nursing have directly corresponded to the three distinct medical phases of care for the acute myocardial infarction patient—arrhythmia detection, pump failure, and limiting infarct size. Nursing care delivery in the cardiac setting, the cardiac patient, and the role of the cardiac nurse each have undergone changes over the years, which together has provided a challenge to health care delivery. Future effects of technological and pharmacologic advances, social changes, and nursing professional practice issues on cardiac care delivery are imperative to consider as health care moves into the …
Incomplete Versus Complete Myocardial Infarction, Mihai Gheorghiade, Sidney Goldstein
Incomplete Versus Complete Myocardial Infarction, Mihai Gheorghiade, Sidney Goldstein
Henry Ford Hospital Medical Journal
Incomplete myocardial infarction (MI), when compared with a complete Ml. is characterized by a small infarct size and a large mass of viable but jeopardized myocardium within the perfusion zone of the infarct-related vessel that is manifested clinically by early recurrent infarction. The pathophysiology involves early spontaneous or thrombolytic reperfusion. Clinical (i.e., residual ischemia), electrocardiographic, and echocardiographic findings and magnitude of serum cardiac enzyme elevations should be taken into account in diagnosing an incomplete MI.
Post Myocardial Infarction Risk Stratification: 1991 Perspective, Michael Lesch
Post Myocardial Infarction Risk Stratification: 1991 Perspective, Michael Lesch
Henry Ford Hospital Medical Journal
No abstract provided.
Management Of Cardiogenic Shock Complicating Acute Myocardial Infarction: The Henry Ford Hospital Experience And Review Of The Literature, Ali R. Moosvi, Mihai Gheorghiade, Sidney Goldstein, Fareed Khaja
Management Of Cardiogenic Shock Complicating Acute Myocardial Infarction: The Henry Ford Hospital Experience And Review Of The Literature, Ali R. Moosvi, Mihai Gheorghiade, Sidney Goldstein, Fareed Khaja
Henry Ford Hospital Medical Journal
Cardiogenic shock complicating acute myocardial infarction (MI) carries a high mortality which in some series prior to 1980 exceeded 80%. Neither the use of inotropic and vasopressor agents nor intraaortic balloon counterpulsation was found to improve survival in this group of patients. Intravenous thrombolytic agents improve survival in patients with acute MI, but their role in cardiogenic shock is unknown. Reports of the use of surgical and mechanical interventions in patients with severe left ventricular dysfunction were examined to determine if there was any benefit to be derived from restoring blood flow to ischemic areas of the myocardium. It was …
Current Issues In The Leukemias, Howard R. Terebelo
Current Issues In The Leukemias, Howard R. Terebelo
Henry Ford Hospital Medical Journal
No abstract provided.
Antimicrobial Chemotherapy In The Intensive Care Unit, Louis D. Saravolatz
Antimicrobial Chemotherapy In The Intensive Care Unit, Louis D. Saravolatz
Henry Ford Hospital Medical Journal
No abstract provided.
Management Of Terminal Illness: The Hospice Concept Of Care, Josefina B. Magno
Management Of Terminal Illness: The Hospice Concept Of Care, Josefina B. Magno
Henry Ford Hospital Medical Journal
No abstract provided.
Why Palliative Medicine?, Robert G. Twycross
Why Palliative Medicine?, Robert G. Twycross
Henry Ford Hospital Medical Journal
No abstract provided.
Predicting Survival In The Advanced Cancer Patient, Robert J. Miller
Predicting Survival In The Advanced Cancer Patient, Robert J. Miller
Henry Ford Hospital Medical Journal
No abstract provided.
Caring For The Terminally Ill: Communicating With Patients And Family, Dana G. Cable
Caring For The Terminally Ill: Communicating With Patients And Family, Dana G. Cable
Henry Ford Hospital Medical Journal
Caring for terminally ill patients requires effective communication skills. It is important that medical personnel understand appropriate ways to communicate with the patient in order to inform him about his illness, throughout its duration. Physicians must develop an understanding of how patients communicate and ways to respond to that communication. Furthermore, the physician needs to communicate with the family of the terminally ill patient. Effective communication must become a regular part of the treatment.
Chronic Myelogenous Leukemia: Molecule To Man, Robert Peter Gale
Chronic Myelogenous Leukemia: Molecule To Man, Robert Peter Gale
Henry Ford Hospital Medical Journal
Chronic myelogenous leukemia (CML) is the best understood human cancer. The molecular basis of CML involves activation of a cellular proto-oncogene—ABL. The consequence is to increase tyrosine kinase activity. This results in a marked clonal increase in the myeloid mass. Later on, cellular maturation is blocked and the decrease eventuates in acute leukemia. Abnormalities of other proto-oncogenes or antioncogenes, like P53, may be involved in leukemia progression. Treatment of CML involves chemotherapy and, more recently, interferon. Whether this treatment prolongs survival or increases the likelihood of cure is unknown but either result seems unlikely. Bone marrow transplants which cure about …
Application Of The Polymerase Chain Reaction For Detection Of Minimal Residual Disease Of Hematologic Malignancies, Mark S. Roth, Valeri H. Terry
Application Of The Polymerase Chain Reaction For Detection Of Minimal Residual Disease Of Hematologic Malignancies, Mark S. Roth, Valeri H. Terry
Henry Ford Hospital Medical Journal
Current induction therapies for acute and chronic leukemias and the lymphomas have achieved significant complete remission rates. Despite this initial success, disease recurrence remains a major problem. Relapse from clinically undetectable residual malignant cells is the most likely mechanism of recurrence. Of crucial importance to the clinician is the accurate detection of residual malignant cells prior to clinical relapse. Standard approaches to evaluate for this minimal residual disease (MRD) allow detection only when the malignant clone exceeds 1%. Patients in remission, however, may frequently have residual neoplastic cells that are far below this level. Recently, several investigators have adapted the …
Assessment Of Methylprednisolone Purging Efficacy On Daudi Burkitt Lymphoma Cells From Normal Bone Marrow, Nalini Janakiraman, Loreen M. Niewenhuis
Assessment Of Methylprednisolone Purging Efficacy On Daudi Burkitt Lymphoma Cells From Normal Bone Marrow, Nalini Janakiraman, Loreen M. Niewenhuis
Henry Ford Hospital Medical Journal
Studies on normal bone marrow and Daudi Burkitt lymphoma cells were performed to determine the efficacy of selective, in vitro chemopurging with methylprednisolone (MP). We found that MP reduces the numher of lymphoma cells without significant damage to bone marrow cells. This information is important because we need to improve the existing in vitro purging regimens used to cleanse autologous marrows of metastatic disease before transplantation into cancer patients who have received high-dose chemotherapy. Normal human bone marrow (NBM) and Daudi lymphoma cells were trealed in parallel with various purging regimens. NBM death was evaluated using soft-agar culture, while Daudi …
Capsaicin: A Therapeutic Option For Painful Diabetic Neuropathy, Karen M. Basha, Fred W. Whitehouse
Capsaicin: A Therapeutic Option For Painful Diabetic Neuropathy, Karen M. Basha, Fred W. Whitehouse
Henry Ford Hospital Medical Journal
Fifteen patients with diabetes mellitus who had painful diabetic neuropalhy (PDN) were enrolled in a double-blind study to test the safety and efficacy of capsaicin 0.075% (Axsain, Genderm, Northbrook, IL). Twelve of the 15 patients completed the eight-week sludy. Nine of the 12 patients reported symptomatic relief; of these nine, five used the drug and four used the vehicle. The three patients who reported no relief of symptoms applied the vehicle. Capsaicin is potentially effective when burning pain is a major symptom of PDN. The side effects of capsaicin were limited and minimal. This agent should be considered by clinicians …
Quality Of Life: What Does It Mean?, Joyce A. Deshano
Quality Of Life: What Does It Mean?, Joyce A. Deshano
Henry Ford Hospital Medical Journal
No abstract provided.
Palliative Care In The 1990s: Special Issues, Derek Doyle
Palliative Care In The 1990s: Special Issues, Derek Doyle
Henry Ford Hospital Medical Journal
No abstract provided.
New Purine Analogues For The Treatment Of Chronic B-Cell Malignancies, Thomas E. Gribbin
New Purine Analogues For The Treatment Of Chronic B-Cell Malignancies, Thomas E. Gribbin
Henry Ford Hospital Medical Journal
Adenosine deaminase (ADA). a purine salvage pathway enzyme, appears to play a key role in normal lymphocyte growth, development, and differentiation. Three new purine nucleoside analogues, deoxycoformycin, fludarahine, and 2-chlorodeoxyadenosine, affect the normal function of the purine salvage pathway by inhibiting ADA or by acting as analogs of the ADA substrates. These agents show significant activity in the treatment of chronic B-cell leukemias and low-grade lymphomas. The pharmacology, mechanism of action, and clinical usefulness of these agents are discussed.
Peripheral Blood Stem Cell Transplantation As An Alternative To Bone Marrow Transplantation: An Overview, Nalini Janakiraman
Peripheral Blood Stem Cell Transplantation As An Alternative To Bone Marrow Transplantation: An Overview, Nalini Janakiraman
Henry Ford Hospital Medical Journal
Stem cells capable of restoring hematopoiesis following lethal bone marrow injury circulate in the blood of many animals, including humans. When collected through leukapheresis and reinfused following high-dose chemotherapy, stem cells offer a treatment option not currently open to some patients who are unable to undergo autologous bone marrow transplantation because of tumor involvement in the pelvis, prior pelvic radiation, or intolerance to general anesthesia. After stem cell infusion, hematologic and immunologic recovery are rapid in comparison to that after autologous hone marrow reinfusion: however, in some cases platelet engraftment is slower. There is some evidence that tumor contamination in …
Porcine Bioprosthetic Aortic Valve Endocarditis With Ring Abscess And Aortic Stenosis, Reda A. Girgis, Howard Rosman, Ramon Del Busto, Maryann Fitzmaurice, Norman A. Silverman
Porcine Bioprosthetic Aortic Valve Endocarditis With Ring Abscess And Aortic Stenosis, Reda A. Girgis, Howard Rosman, Ramon Del Busto, Maryann Fitzmaurice, Norman A. Silverman
Henry Ford Hospital Medical Journal
Porcine bioprosthetic valve endocarditis is an infrequent but serious complication of valve replacement surgery. Ring (or annular) abscess is a frequent finding in mechanical valve endocarditis. In contrast, porcine valve endocarditis most often involves the cusps, and annular infection is uncommon. Porcine valvular dysfunction secondary to endocarditis usually takes the form of incompetence, whereas stenosis is less frequent. We report a case of a 76-year-old female who developed endocarditis wilh Staphylococcus epidermidis nine months after placement of a Carpenter-Edwards porcine aortic valve. Her initial presentation included complete heart block and moderate aortic stenosis. Transesophageal echocardiography aided the diagnosis by demonstrating …
The Department Of Surgery And The Halsted Tradition, Edward R. Munnell
The Department Of Surgery And The Halsted Tradition, Edward R. Munnell
Henry Ford Hospital Medical Journal
No abstract provided.
Hospice Care: An Overview, Josefina B. Magno
Hospice Care: An Overview, Josefina B. Magno
Henry Ford Hospital Medical Journal
No abstract provided.
Nutrition Support Of Hiv+ Patients, Johanna T. Dwyer
Nutrition Support Of Hiv+ Patients, Johanna T. Dwyer
Henry Ford Hospital Medical Journal
Case management strategies for the nutritional support of patients infected with the human immunodeficiency virus (HIV) are evolving as the disease becomes less rapidly fatal and more chronic. Nutritional status changes in advanced HIV infection are similar in many respects to protein-calorie malnutrition. Current clinical effort and research focuses on the beneficial effects of preserving lean body mass and keeping asymptomatic patients in good nutritional status by preventing micronutrient deficiencies and by treating preexisting nutritional problems rather than attempting to intervene late in the disease's course, after secondary malnutrition has already developed. Nutrition support and intervention trials only late in …