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Articles 571 - 600 of 2151
Full-Text Articles in Medical Specialties
Medical Education In The United States: Some Current Problems And An Uncertain Future, Richard J. Reitemeier
Medical Education In The United States: Some Current Problems And An Uncertain Future, Richard J. Reitemeier
Henry Ford Hospital Medical Journal
No abstract provided.
An Overview Of The Newer Antibiotics, Ramon Del Busto
An Overview Of The Newer Antibiotics, Ramon Del Busto
Henry Ford Hospital Medical Journal
The introduction of a large number of new antibiotics has made selecting the one most appropriate for treatment a confusing task for the practicing physician. One problem is that the differences in pharmacokinetics, in vitro activity, and clinical indications between some of these agents may be relatively minor; this is especially true of the new cephalosporins. Another problem is that the generic names of the cephalosporins are so similar that it is impractical, even for the infectious diseases specialist, to be familiar with all of them. This review attempts to summarize the most important characteristics of these new antibiotics and …
Viral Hepatitis: Update On Prevention, Miriam J. Alter
Viral Hepatitis: Update On Prevention, Miriam J. Alter
Henry Ford Hospital Medical Journal
No abstract provided.
Infectious Diseases And The Persisting Microbial Challenge, Louis D. Saravolatz
Infectious Diseases And The Persisting Microbial Challenge, Louis D. Saravolatz
Henry Ford Hospital Medical Journal
No abstract provided.
Prospects For The Medical Use Of Interferon In 1984, Bosko Postic, Julio C. Arroyo
Prospects For The Medical Use Of Interferon In 1984, Bosko Postic, Julio C. Arroyo
Henry Ford Hospital Medical Journal
Interferon, a natural and wide spectrum antiviral polypeptide that was discovered in 1957, has been extensively described. In addition to its antiviral effect, interferon has been found to suppress tumor growth and modulate the immune response. Until 1980, interferon was primarily prepared for clinical trials in human leukocytes derived from the buffy coat of whole blood. A major breakthrough occurred in the late 1970s when human interferon was produced by DNA recombinant methods in such heterologous cells as bacteria (genetic engineering). Interferon is not commercially available in 1984, but it may, based on clinical trials in humans, become part of …
Congenital Seminal Vesicle Cyst: A Specific Diagnosis By Computed Tomography, Leo Drolshagen, Michael A. Sandler
Congenital Seminal Vesicle Cyst: A Specific Diagnosis By Computed Tomography, Leo Drolshagen, Michael A. Sandler
Henry Ford Hospital Medical Journal
Computed tomography (CT) has been shown to be of great value in the assessment of the urinary tract. However, this modality has been primarily used in the evaluation of renal masses and the staging of urinary tract carcinomas. It may also be useful in less common abnormalities, such as mesonephric duct anomalies including congenital seminal vesicle cysts. These lesions are associated with renal agenesis and may produce urinary tract symptoms, or be discovered incidentally. We present a case of a congenital vesicle cyst associated with ipsilateral renal agenesis with characteristic CT findings allowing for a specific diagnosis.
A Case Of Ige Myeloma: Methodology And Review Of The Literature, Pat A. Allevato, Michael J. Deegan, Jau-Wen Chu, Mary B. Perry, Carolyn L. Barth
A Case Of Ige Myeloma: Methodology And Review Of The Literature, Pat A. Allevato, Michael J. Deegan, Jau-Wen Chu, Mary B. Perry, Carolyn L. Barth
Henry Ford Hospital Medical Journal
A 56-year-old man presented with a one-year history of progressive weakness predominantly affecting his extremities and persistent low back pain. Ouchterlony immunodiffusion of the concentrated urine detected a marked increase in lambda light chains. A sternal bone marrow documented a diagnosis of multiple myeloma. Screening high resolution agarose gel electrophoresis revealed diffuse hypogammaglobulinemia and, retrospectively, an equivocal, faint band which migrated in the fast gamma region. By using a combination of Immunoelectrophoresis and immunofixation electrophoresis, this questionable band was determined to represent an IgE lambda monoclonal protein. Radioimmunoassay for IgE documented a serum concentration of 50.6 mg/dl. No intact IgE …
Rapidly Progressive Pancytopenia, Hepatomegaly, And Abnormal Lung Uptake Of Colloid In Systemic Lupus Erythematosus: Possible Saturation Of Reticuloendothelial System With Blood Elements, Tetsushi Sakurai, Kiyoshi Fukuda, Ichiro Kono, Teizo Kabashima, Kazuhide Yamane, Heihachiro Kashiwagi
Rapidly Progressive Pancytopenia, Hepatomegaly, And Abnormal Lung Uptake Of Colloid In Systemic Lupus Erythematosus: Possible Saturation Of Reticuloendothelial System With Blood Elements, Tetsushi Sakurai, Kiyoshi Fukuda, Ichiro Kono, Teizo Kabashima, Kazuhide Yamane, Heihachiro Kashiwagi
Henry Ford Hospital Medical Journal
A patient with systemic lupus erythematosus developed severe abdominal pain and tender hepatomegaly associated with progressive pancytopenia and elevated serum levels of circulating immune complexes. Liver scintigram demonstrated extreme hepatomegaly with poor colloid uptake and splenomegaly with increased colloid uptake. An unusual accumulation of colloid in the lungs was also noted. Subsequent clinical and laboratory studies raised the possibility of saturation of the reticuloendothelial system in the liver by circulating immune complexes and blood cells, a condition demonstrated in experimental animals, but not hitherto well documented in the human immune complex disorder.
Tubal Lavage In The Management Of Ectopic Pregnancy, Samuel A. Motanya, William H. Pfeffer, Emile Sandelin, C. James Chuong
Tubal Lavage In The Management Of Ectopic Pregnancy, Samuel A. Motanya, William H. Pfeffer, Emile Sandelin, C. James Chuong
Henry Ford Hospital Medical Journal
No abstract provided.
Clinical Trials: I. Design And Ethical Issues, Barbara Tilley
Clinical Trials: I. Design And Ethical Issues, Barbara Tilley
Henry Ford Hospital Medical Journal
No abstract provided.
Editorial, Raymond C. Mellinger
Editorial, Raymond C. Mellinger
Henry Ford Hospital Medical Journal
No abstract provided.
Screening Of Patients At High Risk For Cancer, Robert M. O'Bryan
Screening Of Patients At High Risk For Cancer, Robert M. O'Bryan
Henry Ford Hospital Medical Journal
A cancer other than non-melanoma skin cancer will occur in one of every seven persons. Individuals with higher risks for cancer are those with increasing age, hereditary disorders, and a family history of cancer. Lifestyle, especially the use of tobacco and alcohol, diet, and perhaps behavioral patterns influence the risk. Less well understood but clearly pertinent risk factors include environmental and occupational exposures. The risk factors specific for breast cancer include a positive family history of breast cancer, history of mastopathy, age at first pregnancy greater than 35 years, early menarche with late menopause, and history of carcinoma of the …
Brief Communication: Streptokinase For Deep Venous Thrombosis, Barry Lesser, Maria A. Sawdyk
Brief Communication: Streptokinase For Deep Venous Thrombosis, Barry Lesser, Maria A. Sawdyk
Henry Ford Hospital Medical Journal
No abstract provided.
Pericardial Tamponade In Acute Myeloid Leukemia, R. P. Warrier, K. R. Kini, R. Singh, K. Maeda, I. Barr, F. M. Jara
Pericardial Tamponade In Acute Myeloid Leukemia, R. P. Warrier, K. R. Kini, R. Singh, K. Maeda, I. Barr, F. M. Jara
Henry Ford Hospital Medical Journal
We are reporting a case of acute myeloid leukemia in a child with pericardial effusion and cardiac tamponade, with a review of the literature. Morphologic and cytochemical evidence was used to diagnose acute myeloid leukemia, and radiologic, electrocardiographic, echocardiographic, cytologic, and histologic evidence confirmed the diagnosis of tamponade and pericardial leukemic involvement. Pericardiotomy and pericardial window drainage successfully relieved the tamponade, and conventional chemotherapy was used to induce a remission.
Cushing's Disease Due To Pituitary Carcinoma, M. Saeed Zafar, R. C. Mellinger, J. L. Chason
Cushing's Disease Due To Pituitary Carcinoma, M. Saeed Zafar, R. C. Mellinger, J. L. Chason
Henry Ford Hospital Medical Journal
Criteria for the diagnosis of pituitary carcinoma are subject to controversy. Some authors do not accept the demonstration of cellular anaplasia alone as sufficient to establish the diagnosis but require evidence of metastatic disease in order to label a pituitary tumor as malignant. However, pituitary tumors can metastasize even in the absence of anaplasia. The present case of Cushing's disease and pituitary carcinoma had no clinical evidence of metastases when first reported. Partial surgical removal of the tumor followed by irradiation resulted in clinical remission of the Cushing's syndrome, but two years later progressive uncontrollable recurrence of the disease ended …
Peritoneal Lavage Red Blood Cell And White Blood Cell Count: A Prospective Comparison Of Usefulness, Eugene Meyer, James C. Gruenberg
Peritoneal Lavage Red Blood Cell And White Blood Cell Count: A Prospective Comparison Of Usefulness, Eugene Meyer, James C. Gruenberg
Henry Ford Hospital Medical Journal
Prospectively, 637 patients with blunt or penetrating trauma to the lower chest or abdomen had quantitative peritoneal lavage red blood cell (RBC) and white blood cell (WBC) counts as part of their initial diagnostic evaluation. Statistically, the lavage RBC count (error rate: 6.8%) was a superior test to the lavage WBC count (error rate: 9.7%) (chi sq=9.2564, p=0.0024). See Appendix. When the lavage RBC and WBC tests agreed, the predictive value was high: 94% (46/49) when both were positive and 95% (521/549) when both were negative. When the lavage RBC test was positive and the lavage WBC test was negative, …
Why Cancer?, Angelos A. Kambouris
Why Cancer?, Angelos A. Kambouris
Henry Ford Hospital Medical Journal
No abstract provided.
Family History As A Marker For Increased Risk Of Breast Cancer And Colon Cancer, Robert A. Norum
Family History As A Marker For Increased Risk Of Breast Cancer And Colon Cancer, Robert A. Norum
Henry Ford Hospital Medical Journal
Cancer of the breast and colon are well known to occur with high frequency in families with certain inherited cancer syndromes. These cancers also occur with increased frequency in families which do not have a recognizable genetic cancer syndrome. The fact of familial occurrence can be used to identify people with increased risk of cancer. In high-risk people methods for early detection can be developed which may reduce morbidity and mortality from these cancers, as has been done for certain inherited cancer syndromes.
External Beam Treatment Of Inoperable Non-Small Cell Carcinoma Of The Lung, H. Gunter Seydel
External Beam Treatment Of Inoperable Non-Small Cell Carcinoma Of The Lung, H. Gunter Seydel
Henry Ford Hospital Medical Journal
External beam radiation therapy for unresectable non-small cell carcinoma of the lung has produced significant survival in patients with disease limited to one hemithorax. New approaches to improve the results of radiation treatment of these patients include interstitial implantation, the use of hypoxic cell sensitizers, biologic response modifiers, as well as changes in the technique of radiation therapy. This includes the use of modern computerized tomographic scanning technology for better definition of tumor volume as well as the use of two fractions per day in the treatment of non-small cell carcinoma of the lung. Initial results of these studies are …
The Spectrum Of B Cell Neoplasia, Michael J. Deegan
The Spectrum Of B Cell Neoplasia, Michael J. Deegan
Henry Ford Hospital Medical Journal
Recent progress in our understanding of the immune system and the development of new techniques that permit the precise identification of lymphocytes have permitted a reexamination of lymphoid neoplasms. Most of the non-Hodgkin's lymphomas and lymphocytic leukemias have been characterized as T or B cell neoplasms and have been shown to possess features similar to those expressed by normal lymphoid cells at different stages of maturation. The clinical significance and therapeutic implications of these discoveries are now being explored. This paper presents a concise overview of the differentiation of human B lymphocytes, the surface and cytoplasmic markers that permit their …
Preoperative Chemotherapy And Irradiation In The Treatment Of Soft Tissue Sarcomas Of The Lower Extremities: Preliminary Report Of Experience At Henry Ford Hospital, S. David Nathanson
Preoperative Chemotherapy And Irradiation In The Treatment Of Soft Tissue Sarcomas Of The Lower Extremities: Preliminary Report Of Experience At Henry Ford Hospital, S. David Nathanson
Henry Ford Hospital Medical Journal
The development of effective chemotherapy and improved techniques of radiation therapy offer the possibility of managing soft tissue sarcomas so that surgery may need to be less radical than in the past and amputation can be avoided. The low rates of local-regional and systemic recurrence that have resulted from using innovative combinations of chemotherapy, radiation therapy, and conservative surgery encouraged us to use preoperative intraarterial adriamycin (doxorubicin) with or without radiation therapy for three cases of soft tissue sarcomas of the lower extremities. The rationale for this therapy is also discussed.
The Current Controversies In Surgical Management Of Early Breast Cancer, Angelos A. Kambouris
The Current Controversies In Surgical Management Of Early Breast Cancer, Angelos A. Kambouris
Henry Ford Hospital Medical Journal
No abstract provided.
Elevated Serum Transaminase As A Presenting Clue For Precirrhotic Hemochromatosis, Lester P. Kobylak
Elevated Serum Transaminase As A Presenting Clue For Precirrhotic Hemochromatosis, Lester P. Kobylak
Henry Ford Hospital Medical Journal
For patients in whom unexplained elevations in SGOT and SGPT concentrations are found, determination of the serum iron level is recommended to screen for asymptomatic precirrhotic hemochromatosis. Care must be taken to differentiate between hereditary hemochromatosis and secondary iron accumulation due to liver disease.
Is Normal "Normal"?, Craig C. Foreback
Is Normal "Normal"?, Craig C. Foreback
Henry Ford Hospital Medical Journal
No abstract provided.
Polymicrobal Pneumonia In A Corticosteroid-Treated Patient With Chronic Obstructive Lung Disease, John R. Haapaniemi, John Popovich Jr.
Polymicrobal Pneumonia In A Corticosteroid-Treated Patient With Chronic Obstructive Lung Disease, John R. Haapaniemi, John Popovich Jr.
Henry Ford Hospital Medical Journal
The immunosuppressive properties of corticosteroids are well established and cause a depression of pulmonary defense mechanisms. We report the case of a patient treated with short-term corticosteroids for an exacerbation of chronic obstructive lung disease who developed a multiple organism pneumonia.
Neurosonology: An Update, Beatrice L. Madrazo, Manuel Dujovny, Juan Fuentes, Michael A. Sandler, Madelyne Galvin
Neurosonology: An Update, Beatrice L. Madrazo, Manuel Dujovny, Juan Fuentes, Michael A. Sandler, Madelyne Galvin
Henry Ford Hospital Medical Journal
Recent technological advances in diagnostic ultrasound have resulted in the development of high-resolution, portable real-time scanners. In neurological ultrasound, these devices have been particularly useful for detecting intracranial hemorrhage in premature infants. Sonography is now being used during neurosurgical procedures to help in localizing masses for resection and biopsy, as well as in the placement of shunt catheters. The applications of neurosonology and our experience with intraoperative neurosonology are reported in this review.