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Articles 301 - 330 of 2151
Full-Text Articles in Medical Specialties
Clinical Disorders Of Bone And Mineral Metabolism, Michael Kleerekoper
Clinical Disorders Of Bone And Mineral Metabolism, Michael Kleerekoper
Henry Ford Hospital Medical Journal
No abstract provided.
A Tribute To Dr. Boy Frame, John T. Potts Jr.
A Tribute To Dr. Boy Frame, John T. Potts Jr.
Henry Ford Hospital Medical Journal
No abstract provided.
Bone Remodeling, A. M. Parfitt
Bone Remodeling, A. M. Parfitt
Henry Ford Hospital Medical Journal
No abstract provided.
Allied Disciplines, Stephen M. Krane
Allied Disciplines, Stephen M. Krane
Henry Ford Hospital Medical Journal
No abstract provided.
Paget Bone Disease And Heredity: A Case Report, Donato Agnusdei, Roberto Civitelli, Angelo Camporeale, Carlo Gennari
Paget Bone Disease And Heredity: A Case Report, Donato Agnusdei, Roberto Civitelli, Angelo Camporeale, Carlo Gennari
Henry Ford Hospital Medical Journal
Evidence on familial aggregation of Paget disease of bone shows that the trait is controlled by a single dominant gene. Due to the late onset of the disease, the primary biochemical abnormalities leading to the characteristic roentgenographic features are still unknown. We report the case of a 24-year-old woman who had an elevated serum alkaline phosphatase on routine analysis. Family history revealed that her father and paternal grandmother had Paget bone disease. This pattern is compatible with an autosomic dominant inheritance. Complete laboratory workup confirmed high heat labile alkaline phosphatase values, along with high serum osteocalcin and urinary hydroxyproline excretion. …
Metabolic Bone Disease And The Hip, Robert Lindsay
Metabolic Bone Disease And The Hip, Robert Lindsay
Henry Ford Hospital Medical Journal
No abstract provided.
Miscellaneous Disorders Of Calcium And Bone Metabolism, Gregory R. Mundy
Miscellaneous Disorders Of Calcium And Bone Metabolism, Gregory R. Mundy
Henry Ford Hospital Medical Journal
No abstract provided.
Newer Therapies In Hypercalcemia And Metabolic Bone Disease, Hunter Heath Iii
Newer Therapies In Hypercalcemia And Metabolic Bone Disease, Hunter Heath Iii
Henry Ford Hospital Medical Journal
No abstract provided.
Osteoporosis As A Community Health Problem: Lessons Learned From Studying Hypertension, Michael Kleerekoper, Dorothy A. Nelson
Osteoporosis As A Community Health Problem: Lessons Learned From Studying Hypertension, Michael Kleerekoper, Dorothy A. Nelson
Henry Ford Hospital Medical Journal
Campaigns to increase the medical and lay communities' awareness and understanding of the problems of unrecognized and untreated hypertension have led to a progressive decline in morbidity and mortality from hypertension-related diseases. While osteoporosis is also a community health problem, educational and awareness campaigns are still in their infancy and decades may pass before these result in a declining morbidity and mortality from osteoporosis. We identify areas where concepts learned from years of hypertension research might be applicable lo the study of osteoporosis as a community health problem and thereby lessen the time needed to effect a declining morbidity and …
Significance Of Antinuclear Antibody (Ana) Immunofluorescent Patterns And Titers In Systemic Lupus Erythematosus Nephritis, Syed Akbar, Abel I. Tello, Usana Luvira, Rollin Heinzerling, Raymond Romanski, Nathan W. Levin, Thomas K. H. Burnham
Significance Of Antinuclear Antibody (Ana) Immunofluorescent Patterns And Titers In Systemic Lupus Erythematosus Nephritis, Syed Akbar, Abel I. Tello, Usana Luvira, Rollin Heinzerling, Raymond Romanski, Nathan W. Levin, Thomas K. H. Burnham
Henry Ford Hospital Medical Journal
Seventy-three patients with systemic lupus erythematosus (SLE) nephritis were studied for up to eight years using sequential serologic and renal function tests and renal biopsies. Antinuclear antibody (ANA) patterns and titers were classified into two systems: nonparticulate and particulate. We found a close relationship between disease activity and changes in titers of the nonparticulate peripheral homogeneous system. These changes predicted imminent flare-up or immunosuppressive induced remission of nephritis. Patients with the thready ANA pattern (part of the particulate system) as the main pattern showed a predominant association with membranous glomerulopathy and better renal function than those without threads. The association …
Obesity And Hypertension: A Review, Khaled Imam, James R. Sowers
Obesity And Hypertension: A Review, Khaled Imam, James R. Sowers
Henry Ford Hospital Medical Journal
Hypertension is an important risk factor for cardiovascular morbidity and mortality. Obesity is often associated with hypertension. This strong association can be attributed to several pathophysiological changes which occur in obese subjects: increased salt and caloric intake, increased blood volume, increased cardiac output, increased basal as well as stress-stimulated sympathetic nervous system activity, hyperinsulinemia, and a relative increase in renin and aldosterone. Obesity usually increases the preload and causes an eccentric cardiac hypertrophy, while hypertension increases the afterload and causes concentric cardiac hypertrophy. When both obesity and hypertension occur in the same patient (as is often the case), they present …
Biophysical Methods For Estimating In Vivo Body Composition: The Determination Of The Adipose Compartment, Luther E. Preuss, Frank P. Bolin
Biophysical Methods For Estimating In Vivo Body Composition: The Determination Of The Adipose Compartment, Luther E. Preuss, Frank P. Bolin
Henry Ford Hospital Medical Journal
The status of the human body's major components (adipose mass, lean mass, body water, etc) and their change with time are of clinical importance. Deviation of these body components from a stable condition may be imposed by nutrition or disease, and a return to the normal body state may be brought about by appropriate medical care. Thus accurate quantitation of these components is an important goal. This field of study can be traced to the early 1800s, with a major thrust starting in the 1940s and continuing lo the present. The last four decades have shown an accelerated development of …
Morbidity And Treatment Of Clinically Important Obesity: An Internal Medicine Perspective, J. David Fachnie
Morbidity And Treatment Of Clinically Important Obesity: An Internal Medicine Perspective, J. David Fachnie
Henry Ford Hospital Medical Journal
Obesity is defined as an excess storage of energy in the form of fat. The internist generates a differential diagnosis of etiologic factors and examines the patient carefully. Obese persons are counseled on all medical risks of obesity. Choices for treatment vary according lo the severity of the obesity, and alternative dietary treatments include a balanced-deficit diet or a very low calorie diet. Weight loss can be predicted by applying specified equations. With severe obesity, multidisciplinary treatment is needed. Anorexic agents have limited value because of their side effects and because of weight increase after discontinuing therapy. Obesity is not …
Obese Father William Meets A Physician, J. David Fachnie
Obese Father William Meets A Physician, J. David Fachnie
Henry Ford Hospital Medical Journal
No abstract provided.
Minnesota Multiphasic Personality Profiles Of The Morbidly Obese, Philip J. Lanzisera, Allan Dehorn, Carolyn Macdonald, Conni Sroka, J. David Fachnie
Minnesota Multiphasic Personality Profiles Of The Morbidly Obese, Philip J. Lanzisera, Allan Dehorn, Carolyn Macdonald, Conni Sroka, J. David Fachnie
Henry Ford Hospital Medical Journal
Minnesota Multiphasic Personality Inventory profiles of 132 morbidly obese individuals participating in a protein-sparing modified fast were examined via factor analytic methods yielding five interpretable psychometric factors. The results support the hypothesis that the morbidly obese are a psychologically heterogeneous population which can be subdivided conceptually. However, the findings fail to support the hypothesis that any particular psychopathology is intricately linked to the development of morbid obesity.
Blood Pressure Changes And Weight Changes In Hypertensive Patients In An Inner-City Clinic, A. David Goldberg, Frits Van Der Kuyp, Pamela C. Keenen
Blood Pressure Changes And Weight Changes In Hypertensive Patients In An Inner-City Clinic, A. David Goldberg, Frits Van Der Kuyp, Pamela C. Keenen
Henry Ford Hospital Medical Journal
The association of obesity and hypertension has been clearly established. Despite evidence that weight loss reduces blood pressure, this aspect of treatment is often not stressed. We studied the effects of nutritional intervention in a group of inner-city, predominantly black, hypertensive patients to determine resultant blood pressure changes. Weight reduction was achieved by 57% of the patients, with a loss of more than 4.5 kg (10 lb) in 18%. Changes in weight were highly correlated with blood pressure changes. Correlations were greater for systolic than diastolic pressures, for pressure measured in the standing than the supine position, and for men …
Surgery For Morbid Obesity: A Continuing Challenge, Brack A. Bivins, Farouck N. Obeid, H. Mathilda Horst, Victor J. Sorensen
Surgery For Morbid Obesity: A Continuing Challenge, Brack A. Bivins, Farouck N. Obeid, H. Mathilda Horst, Victor J. Sorensen
Henry Ford Hospital Medical Journal
No abstract provided.
Occurrence Of Alzheimer Disease In Michigan: An Epidemiologic Review Of Rates And Risk Factors, Christine Cole Johnson
Occurrence Of Alzheimer Disease In Michigan: An Epidemiologic Review Of Rates And Risk Factors, Christine Cole Johnson
Henry Ford Hospital Medical Journal
Alzheimer disease is a progressive degenerative neurological disorder of insidious onset characterized by the deterioration of cognitive functioning. Little is known about the etiology and epidemiology of this condition. The only risk factor consistently associated with Alzheimer disease is advancing age. As the population of the elderly continues to grow, many public agencies, including those in Michigan, are concerned about social, personal, and financial implications and seek estimates of the number of people with dementia. To date, mortality rates based on vital statistics have been noninformative because Alzheimer disease is difficult lo diagnose clinically and has been considered to be …
Conrad Ramsey Lam, Md: Henry Ford Hospital's First Heart Surgeon, Donald J. Magilligan
Conrad Ramsey Lam, Md: Henry Ford Hospital's First Heart Surgeon, Donald J. Magilligan
Henry Ford Hospital Medical Journal
No abstract provided.
A Mathematical Model Of Lung Static Pressure-Volume Relationships: Comparison Of Clinically Derived Parameters Of Elasticity, William Benish, Peggy Harper, Joseph Ward, John Popovich Jr.
A Mathematical Model Of Lung Static Pressure-Volume Relationships: Comparison Of Clinically Derived Parameters Of Elasticity, William Benish, Peggy Harper, Joseph Ward, John Popovich Jr.
Henry Ford Hospital Medical Journal
We constructed a simple model of lung distensibility in which the relationship between pressure (P) and volume (V) is of the exponential form obtained empirically: V = a+ becP , where a, b, and c are constants, and e is the base of the natural logarithm. The model lung is idealized as a frictionless diaphragm moving in a cylinder. Diaphragm movement is impeded by a variable force (F). By assuming that the rate of change of F is proportional to the inverse of the distance of the diaphragm from a maximal distance, the pressure-volume relationship assumes the above exponential form. …
Anticoagulant And Antithrombotic Therapy In Deep Venous Thrombosis And Pulmonary Embolism, Paul D. Stein
Anticoagulant And Antithrombotic Therapy In Deep Venous Thrombosis And Pulmonary Embolism, Paul D. Stein
Henry Ford Hospital Medical Journal
No abstract provided.
A Double-Blind Trial Of Protriptyline In The Treatment Of Sleep Apnea Syndrome, Edward J. Stepanski, William A. Conway, David K. Young, Frank J. Zorick, Robert M. Wittig, Thomas Roth
A Double-Blind Trial Of Protriptyline In The Treatment Of Sleep Apnea Syndrome, Edward J. Stepanski, William A. Conway, David K. Young, Frank J. Zorick, Robert M. Wittig, Thomas Roth
Henry Ford Hospital Medical Journal
Eight male subjects with sleep apnea syndrome were given placebo and protriptyline in a double-blind crossover design to evaluate the effects of protriptyline on respiration during sleep. Treatment with protriptyline produced significantly better oxygenation and significantly fewer arousals during sleep, but sleep staging was unchanged. The decreased number of respiratory events approached significance and was much greater in six of eight subjects. A rapid eye movement sleep-suppression explanation of the improvement in oxygenation is not supported. Alternative explanations of these findings are discussed.
Sleep-Wake Complaints And Their Relation To Sleep Disturbance, De Ton, Frank J. Zorick, Timothy A. Roehrs, Robert M. Wittig, Jeanne M. Sicklesteel, Thomas Roth
Sleep-Wake Complaints And Their Relation To Sleep Disturbance, De Ton, Frank J. Zorick, Timothy A. Roehrs, Robert M. Wittig, Jeanne M. Sicklesteel, Thomas Roth
Henry Ford Hospital Medical Journal
This report is a comparison of patients presenting with 1) an insomnia complaint diagnosed as no objective findings. 2) insomnia diagnosed as being associated with a psychiatric disorder, and 3) daytime sleepiness diagnosed as no objective findings. The sleep of patients with insomnia diagnosed as no objective findings is comparable to that of patients with daytime sleepiness diagnosed as no objective findings and is significantly better than that of patients with insomnia associated with a psychiatric disorder. Significant differences were found in sleep induction, sleep maintenance, and overall sleep efficiency. No major differences were found among any of the groups …
A Prospective Randomized Comparison Of A Single Antibiotic (Moxalactam) Versus Combination Therapy (Gentamicin And Clindamycin) In Penetrating Abdominal Trauma, Theodore Fifer, Farouck N. Obeid, H. Mathilda Horst, Victor J. Sorensen, Larry D. Crots, Brack A. Bivins
A Prospective Randomized Comparison Of A Single Antibiotic (Moxalactam) Versus Combination Therapy (Gentamicin And Clindamycin) In Penetrating Abdominal Trauma, Theodore Fifer, Farouck N. Obeid, H. Mathilda Horst, Victor J. Sorensen, Larry D. Crots, Brack A. Bivins
Henry Ford Hospital Medical Journal
From July 1 to December 31, 1983, 50 consecutive patients undergoing abdominal exploration for penetrating abdominal trauma from stab and gunshot wounds were prospectively randomized to receive postinjury, preoperative antibiotic coverage with moxalactam (2 g intravenously every 12 hours) or a combination of gentamicin (3 to 5 mg/kg/day in three equal doses administered every eight hours) and clindamycin (600 mg intravenously every six hours). No intraabdominal abscesses or wound infections developed, and no direct evidence of toxicity of the antibiotic regimens developed in either group. In the study group, moxalactam therapy was an effective alternative to the combination antibiotic regimen. …
Clinical Significance Of Sleep Desaturation In Hypoxemic Chronic Obstructive Pulmonary Disease: Studies In 130 Patients, William A. Conway, Meir Kryger, Richard M. Timms, George W. Williams
Clinical Significance Of Sleep Desaturation In Hypoxemic Chronic Obstructive Pulmonary Disease: Studies In 130 Patients, William A. Conway, Meir Kryger, Richard M. Timms, George W. Williams
Henry Ford Hospital Medical Journal
We studied 130 patients with hypoxemic chronic obstructive lung disease to determine if nocturnal desaturation aggravates hypoxia-induced complications. All had tests of neuropsychological and physiological function known to be affected by chronic hypoxia. Of the 130 patients, 25 had complete polysomnography and 105 had their sleep judged visually and arterial oxygen saturation recorded continuously. Severe and mild desaturation groups were defined relative to the mean for both mean and maximal sleep desaturation, and the severity of waking complications were compared. No significant differences were noted between patients with mild and severe mean desaturation or maximal desaturation for hematocrit, neuropsychological tests, …