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Articles 121 - 150 of 602
Full-Text Articles in Medical Specialties
Associated Urogenital Injuries Following Pelvic Trauma In Pediatrics, A 15-Year Single-Center Retrospective Studey, Colin Van Wagoner, Ehab Saleh, Sazid Hasan
Associated Urogenital Injuries Following Pelvic Trauma In Pediatrics, A 15-Year Single-Center Retrospective Studey, Colin Van Wagoner, Ehab Saleh, Sazid Hasan
Conference Presentation Abstracts
OBJECTIVE: The association between pelvic trauma and urogenital injuries in adult patients is well established, whereas literature concerning pediatric patients is sparse. The purpose of this study was to determine the association between pelvic trauma and urogenital injuries in the pediatric population including incidence, and trends in injury modality, treatment patterns, imaging, and outcome. METHODS: This was a single-center, retrospective chart review. Patients aged 0-16 years admitted for pelvic fracture, pelvic dislocation, proximal femur fracture, and injury of urinary and pelvic organs over a 15-year period were included. Primary outcomes included fracture diagnosis, urogenital injury diagnosis, treatment modalities, and mechanism …
Operative Vs. Non-Operative Treatment Of Z-Type Clavicle Shaft Fractures In Adolescents: A Retrospective Study, Iulio Dobrin, Colin Van Wagoner, Ehab Saleh
Operative Vs. Non-Operative Treatment Of Z-Type Clavicle Shaft Fractures In Adolescents: A Retrospective Study, Iulio Dobrin, Colin Van Wagoner, Ehab Saleh
Conference Presentation Abstracts
OBJECTIVE: Clavicle fractures are common in both adult and pediatric populations.1 Yet, the literature describes differences regarding treatment in such fractures between these populations, favoring operative treatment for adults and nonoperative treatment for pediatric patients.2 There is particular uncertainty for treating a subgroup of adolescent clavicle fractures known as the Z-type comminuted fracture which, being a completely displaced and complex fracture pattern, can prove to have different healing rates than other midshaft clavicle fractures. Because of concerns about healing and bony prominences, these types of fractures are commonly treated surgically, despite an increasing body of literature indicating equivalent outcomes in …
Metaplastic Breast Cancer: A Retrospective Chart Review Of Clinical Features, Nidhi Navaratna, Mariam Aoun, Nitya Batra, Mohammad M. Chisti
Metaplastic Breast Cancer: A Retrospective Chart Review Of Clinical Features, Nidhi Navaratna, Mariam Aoun, Nitya Batra, Mohammad M. Chisti
Conference Presentation Abstracts
No abstract provided.
Intraoperative Code Status: Moving From Misinformation To Respect For Patient Autonomy, Jacob Applegarth, Jacob M. Morton, Nathan M. Novotny, Ngan Nguyen, Abram Brummett
Intraoperative Code Status: Moving From Misinformation To Respect For Patient Autonomy, Jacob Applegarth, Jacob M. Morton, Nathan M. Novotny, Ngan Nguyen, Abram Brummett
Conference Presentation Abstracts
Introduction: Intraoperative code status represents a complicated topic for patients and providers. Prior studies demonstrated a lack of understanding of intraoperative code status, specifically do not resuscitate (DNR) orders. This misunderstanding appears common despite clear professional recommendations. A recent survey of surgery residents at our institution showed variability in understanding of intraoperative code status policy despite clear institutional guidelines. Few studies utilized simulated education for surgeons and surgical residents to navigate intraoperative DNR status. This project aims to create a simulation-based program for residents to navigate intraoperative DNR status ethically and to assess its impact on learning, practice patterns and …
Increasing Patient Age And General Anesthesia Are Risk Factors For Failure Of Same-Day Discharge Total Hip Arthroplasty, Kevin Xavier Farley, Robert Dean, Mark S. Karadsheh, Drew Douglas Moore
Increasing Patient Age And General Anesthesia Are Risk Factors For Failure Of Same-Day Discharge Total Hip Arthroplasty, Kevin Xavier Farley, Robert Dean, Mark S. Karadsheh, Drew Douglas Moore
Conference Presentation Abstracts
INTRODUCTION: As cost containment efforts in orthopedic surgery increase, there has been a rise in same-day discharge total hip arthroplasty (THA). Same-day discharge THA has been further accelerated by the COVID-19 pandemic and the removal of THA from the Medicare inpatient only list. This study sought to evaluate risk factors for readmission following same-day discharge THA. METHODS: From 2012-2021, the National Surgical Quality Improvement Project database was used to identify all patients undergoing elective THA discharged the day of surgery to their home. Demographic, comorbid, and operative variables were collected, as displayed in Table 1. Readmission within 30-days of surgery …
Second-Site Periprosthetic Joint Infection After Subsequent Primary Hip Or Knee Arthroplasty: Risk Factor Assessment, Daniel Aris Nikolaidis, Devin Young, Robert Runner, Mark S. Karadsheh, Andrew Steffensmeier
Second-Site Periprosthetic Joint Infection After Subsequent Primary Hip Or Knee Arthroplasty: Risk Factor Assessment, Daniel Aris Nikolaidis, Devin Young, Robert Runner, Mark S. Karadsheh, Andrew Steffensmeier
Conference Presentation Abstracts
INTRODUCTION: The risk factors for developing a periprosthetic joint infection (PJI) are well described. However, those associated with developing a second-site or metachronous PJI (MPJI) following a subsequent primary arthroplasty are poorly understood. The purpose of our study is to determine (1) prevalence and (2) risk factors associated with developing a second-site PJI in patients with a prior history of PJI who undergo a subsequent THA or TKA. METHODS: A retrospective, single-center case-control study identified 77 patients treated for an index PJI (hip or knee) between 2013-2022, and who also underwent another primary arthroplasty after completing treatment for their first …
Neuraxial Vs. General Anesthesia In Total Hip Arthroplasty For Femoral Neck Fracture: A Comparison Of Post-Operative Complications, Kevin Xavier Farley, Robert Dean, Mark S. Karadsheh, Drew Douglas Moore
Neuraxial Vs. General Anesthesia In Total Hip Arthroplasty For Femoral Neck Fracture: A Comparison Of Post-Operative Complications, Kevin Xavier Farley, Robert Dean, Mark S. Karadsheh, Drew Douglas Moore
Conference Presentation Abstracts
INTRODUCTION: Rates of complications with differing anesthetic choices has not been directly compared for patients undergoing total hip arthroplasty (THA) for femoral neck fractures. This study sought to directly compare neuraxial vs. general anesthetic use and compare post-operative outcomes for patients undergoing THA for a femoral neck fracture. METHODS: From 2012-2021, the National Surgical Quality Improvement Project (NSQIP) database was used to identify all patients undergoing THA for a femoral neck fracture. Anesthetic type was identified and categorized as neuraxial (spinal, epidural) or general. Demographic and comorbid variables were collected. Days from admission to surgery was also identified. Postoperative complications …
Epigastric Hernia Containing Incarcerated Gallbladder, Katelyn R. Ward, Melanie Ermler, Kathryn M. Ziegler
Epigastric Hernia Containing Incarcerated Gallbladder, Katelyn R. Ward, Melanie Ermler, Kathryn M. Ziegler
Conference Presentation Abstracts
Introduction: Epigastric hernias represent 1.6–3.6% of all abdominal hernias, and usually contain preperitoneal fat and occasionally omentum or small bowel. Rarely, epigastric hernias may contain portions of other organs, such as colon or stomach. We report an unusual case of a patient whose incarcerated epigastric hernia contained her stone-filled gallbladder.over a million performed in the US, and over 20 million worldwide annually. We aim to study and compare interest trends in the US and the World for IHR techniques (open, laparoscopic, robotic) using GT. Methods: The following search topics were analyzed from January 2010 to August 2024 in ‘‘US’’ and …
Left Behind: A Rare Case Of True Gallbladder Sinistroposition And Surgical Implications, Daniel Finn, Jacob Applegarth, Jacob Mesiti, Mario Villalba
Left Behind: A Rare Case Of True Gallbladder Sinistroposition And Surgical Implications, Daniel Finn, Jacob Applegarth, Jacob Mesiti, Mario Villalba
Conference Presentation Abstracts
Objectives: Encountering aberrant biliary anatomy is a known risk factor for inadvertent injury while performing biliary surgery. One described anatomic aberrancy, sinistroposition of the gallbladder (also known as ‘‘left sided gallbladder’’), is a rarely seen anatomic abnormality with an incidence of 0.2% to 1.1%. Given the infrequent encounters with this abnormality and its association with other anatomic anomalies, extreme care and caution should be exercised when performing a cholecystectomy in this patient population. Methods: We present the case of a 37-year-old male who presented with abdominal pain and was diagnosed with Tokyo Grade I acute calculous cholecystitis. An ultrasound of …
Comparing Outcomes After Cemented And Cementless Total Knee Arthroplasty, Phillip Vartanyan, James Feng, Ali Omari, Elijah Christian Auch, Alex Miller, Drew Douglas Moore, Hasson Alosh, Mark S. Karadsheh
Comparing Outcomes After Cemented And Cementless Total Knee Arthroplasty, Phillip Vartanyan, James Feng, Ali Omari, Elijah Christian Auch, Alex Miller, Drew Douglas Moore, Hasson Alosh, Mark S. Karadsheh
Conference Presentation Abstracts
INTRODUCTION: The optimal method of fixation for primary total knee arthroplasties (TKAs) has been subject to debate. Here we compare patients who received cemented and cementless TKAs for arthritis and compared clinical outcome measures. METHODS: All primary TKAs between January 2016 and December 2022 were obtained retrospectively from a prospective institutional database utilized for contribution to a state-wide joint arthroplasty database. Prospective data includes baseline demographics, select medical comorbidities, intraoperative variables, and postoperative course/complications. Patients were split into two cohorts based on the use of cemented vs cementless TKA implants. Hybrid fixation was excluded. Groups were compared utilizing Student’s unpaired …
New-Onset Depression Following Total Shoulder Arthroplasty: The Impact Of Preoperative Patient Factors And Postoperative Complications, Kevin Xavier Farley, Robert Dean, J Michael Wiater
New-Onset Depression Following Total Shoulder Arthroplasty: The Impact Of Preoperative Patient Factors And Postoperative Complications, Kevin Xavier Farley, Robert Dean, J Michael Wiater
Conference Presentation Abstracts
INTRODUCTION: Depression has been well studied as a risk factor for postoperative complications following total shoulder arthroplasty (TSA). However, little is known about new-onset depression (NOD) following TSA. The purpose of this study is to determine the incidence of NOD following TSA and identify risk factors for its occurrence. METHODS: This was a retrospective review of patients undergoing TSA in the Truven Health MarketScan database. NOD was identified. Patients with pre-operative depression were excluded from analysis. Post-operative complications were identified, including the development of a prosthetic joint infection (PJI), need for revision surgery, and postoperative dislocation. If a complication occurred …
Uncemented Versus Cemented Humeral Fixation In Reverse Shoulder Arthroplasty For Proximal Humerus Fractures In The Elderly: A Multicenter Retrospective Cohort Study, Johnny Kasto, Thomas Ward Throckmorton, Tyler James Brolin, H Mike Kim, Curtis R. Noel, J Michael Wiater, Thomas W. Wright, Stephanie J. Muh
Uncemented Versus Cemented Humeral Fixation In Reverse Shoulder Arthroplasty For Proximal Humerus Fractures In The Elderly: A Multicenter Retrospective Cohort Study, Johnny Kasto, Thomas Ward Throckmorton, Tyler James Brolin, H Mike Kim, Curtis R. Noel, J Michael Wiater, Thomas W. Wright, Stephanie J. Muh
Conference Presentation Abstracts
INTRODUCTION: Among surgical interventions for proximal humerus fractures, RSA has been shown to have superior or noninferior outcomes to hemiarthroplasty or open reduction internal fixation. Cemented humeral fixation in RSA has been the traditional treatment method for proximal humerus fractures, however, there is a growing interest in uncemented humeral fixation. Both cemented and cementless RSA are currently used to treat proximal humerus fractures with few studies comparing postoperative outcomes of these 2 techniques. The aim of this study was to compare postoperative outcomes between cemented and uncemented humeral fixation following primary reverse total shoulder arthroplasty (RSA) for proximal humerus fractures. …
Outcomes After Total Hip Arthroplasty: Comparison Between Posterior And Anterior Approaches, Phillip Vartanyan, James Feng, Alex Miller, Ali Omari, Elijah Christian Auch, Hasson Alosh, Drew Douglas Moore, Mark S. Karadsheh
Outcomes After Total Hip Arthroplasty: Comparison Between Posterior And Anterior Approaches, Phillip Vartanyan, James Feng, Alex Miller, Ali Omari, Elijah Christian Auch, Hasson Alosh, Drew Douglas Moore, Mark S. Karadsheh
Conference Presentation Abstracts
INTRODUCTION: The effects of surgical approach in total hip arthroplasty (THA) are often debated. Here we compare patients who underwent THA through a posterior versus anterior approach and compared clinical outcomes and patient reported outcome measures (PROMs). METHODS: All primary THAs between January 2016 and December 2022 were obtained retrospectively from a prospective institutional database utilized for contribution to a state-wide joint arthroplasty database. Prospective data was abstracted including baseline demographics, select medical comorbidities, intraoperative variables, postoperative course/complications and patient reported outcomes. Two cohorts were developed based on approach: anterior (aTHA) and posterior (pTHA) THA. Cohort groups were compared utilizing …
Two-Year Follow-Up Of Additive Manufactured, Fully 3d Printed Humeral Prosthesis, Jie Jonathan Yao, Andrew Jawa, J Michael Wiater, Anand M. Murthi, Matthew J. Smith, Derek J. Cuff, Samantha Anne Riebesell, Dennis Debernardis, Luke Stanford Austin
Two-Year Follow-Up Of Additive Manufactured, Fully 3d Printed Humeral Prosthesis, Jie Jonathan Yao, Andrew Jawa, J Michael Wiater, Anand M. Murthi, Matthew J. Smith, Derek J. Cuff, Samantha Anne Riebesell, Dennis Debernardis, Luke Stanford Austin
Conference Presentation Abstracts
INTRODUCTION: A fully 3D printed prosthetic may offer numerous potential advantages including improved pore precision, overall porosity, topology optimization, spatial variability in stiffness, communication between pores, and strut size. However, there are numerous theoretical concerns surrounding inferior mechanical performance with fully 3D printed implants (e.g. potentially higher rates of fatigue, increased in vivo particle release, etc.) compared to conventionally fabricated ones. We are aware of no reports on the clinical performance of fully 3D printed, off-the-shelf, humeral prostheses. To validate fully 3D printed humeral designs, the purpose of this study was to provide minimum 2-year postoperative clinical outcomes and survivorship …
Polyethylene Wear: An Under-Recognized Cause Of Failed Shoulder Arthroplasty, Brandon Fisher, Matthew Astolfi, Justin Taylor Deslaurier, Karen Childers, James Youngjin Lee, Marisa Samani, J Michael Wiater
Polyethylene Wear: An Under-Recognized Cause Of Failed Shoulder Arthroplasty, Brandon Fisher, Matthew Astolfi, Justin Taylor Deslaurier, Karen Childers, James Youngjin Lee, Marisa Samani, J Michael Wiater
Conference Presentation Abstracts
INTRODUCTION: Particle-induced osteolytic and chronic inflammatory effects of polyethylene (PE) wear are a source of failure after both anatomic total shoulder arthroplasty (ATSA) and reverse total shoulder arthroplasty (RTSA). Historically, PE wear has rarely been reported as a cause of revision in the setting of prior shoulder arthroplasty, unlike hip and knee counterparts. The goal of this study was to analyze and present the clinical, radiographic, and intra-operative findings in a consecutive series of patients who presented after shoulder arthroplasty with evidence of PE wear. METHODS: This was a retrospective review of prospectively collected data on a consecutive series of …
Are Pre-Operative Falls Associated With Post-Operative Complications In Patients Undergoing Aseptic Revision Hip Or Knee Arthroplasty?, Kevin Xavier Farley, Robert Dean, Mark S. Karadsheh, Drew Douglas Moore
Are Pre-Operative Falls Associated With Post-Operative Complications In Patients Undergoing Aseptic Revision Hip Or Knee Arthroplasty?, Kevin Xavier Farley, Robert Dean, Mark S. Karadsheh, Drew Douglas Moore
Conference Presentation Abstracts
INTRODUCTION: Pre-operative falls are common in patients undergoing primary hip or knee arthroplasty and pre-dispose patients to poor outcomes. However, this relationship in those undergoing revision hip and knee arthroplasty (rTHA, rTKA) is unclear. This study sought to study the relationship between a pre-operative fall history and post-operative patient complications in patients undergoing rTKA or rTHA. METHODS: The National Surgical Quality Improvement Project (NSQIP) database was used to identify all patients undergoing aseptic rTKA or rTHA. The variable for a fall history was available in 2021. Fall history was defined as a patient with a fall in the 6- months …
Serum Metal Ion Levels In Patients Undergoing Revision Should Arthroplasty, Rishi Chatterji, Brandon Fisher, Avianna Elizabeth Arapovic, Yuying Xing, J Michael Wiater
Serum Metal Ion Levels In Patients Undergoing Revision Should Arthroplasty, Rishi Chatterji, Brandon Fisher, Avianna Elizabeth Arapovic, Yuying Xing, J Michael Wiater
Conference Presentation Abstracts
INTRODUCTION: Shoulder arthroplasty systems are transitioning towards more modular prosthesis options with the goal of reducing complication profiles and increasing range of motion. Modularity may increase the potential for fretting, corrosion, and subsequent release of metal ions. These events have been associated with adverse reactions in hip and knee arthroplasty, but not in the setting of revision shoulder arthroplasty. The purpose of this study was to identify associations between implant designs, metallurgy, patient characteristics, and serum metal ion levels in patients undergoing revision shoulder arthroplasty. METHODS: 51 patients that underwent revision shoulder arthroplasty were retrospectively reviewed based on prospectively collected …
Home, Sweet Home: An Evaluation Of The Relationship Between Food Environment And Diabetes In Pregnancy, Symone Mcclain, Tiffany Clinton, Alicia Speak, Jessica Flint, Allison Fly, Tylar Louise Marie Dickson, Briana Marin, Miranda Goodson, Sun Kwon Kim, Raminder Khangura, D'Angela S. Pitts
Home, Sweet Home: An Evaluation Of The Relationship Between Food Environment And Diabetes In Pregnancy, Symone Mcclain, Tiffany Clinton, Alicia Speak, Jessica Flint, Allison Fly, Tylar Louise Marie Dickson, Briana Marin, Miranda Goodson, Sun Kwon Kim, Raminder Khangura, D'Angela S. Pitts
Conference Presentation Abstracts
Objective: Access to healthy and nutritious food is a basic human right, although it has become a critical social determinant of health. Lack of healthy food access has been linked to poorer health outcomes and chronic preventable health conditions, especially in our most vulnerable populations. Previous research has suggested mixed results with food insecurity and type 2 diabetes (T2DM) and gestational diabetes (GDM). This study’s objective is to explore the impact of living in a low food access environment (LAFE) on the incidence of T2DM and GDM in pregnant patients Study Design: This study was a retrospective chart review from …
Ai Significantly Improves Detection Of Prenatal Ultrasounds Suspicious For Major Congenital Heart Defects By Obgyn/Mfms, Jennifer Lam-Rachlin, Rajesh Punn, Sarina K. Behera, Miwa Geiger, Matthias Lachaoud, Nadine David, Sara Garmel, Matthew K. Janssen, Kendra Sylvestser, John Kennedy
Ai Significantly Improves Detection Of Prenatal Ultrasounds Suspicious For Major Congenital Heart Defects By Obgyn/Mfms, Jennifer Lam-Rachlin, Rajesh Punn, Sarina K. Behera, Miwa Geiger, Matthias Lachaoud, Nadine David, Sara Garmel, Matthew K. Janssen, Kendra Sylvestser, John Kennedy
Conference Presentation Abstracts
Objective: Congenital heart defects (CHDs) are a leading cause of infant morbidity and mortality partly due to low prenatal detection rates. We evaluated whether an artificial intelligence (AI) system can improve the detection of CHDs on fetal ultrasound exams among both general OBGYNs and MFM specialists. Study Design: The AI system analyzes all grayscale 2D ultrasound cines of an exam and detects 8 morphological findings associated with severe CHDs. The presence of any such finding should justify patient referral for further examination. The AI system identifies each finding as present, absent or inconclusive, and highlights frames where findings can be …
Cerebroplacental Doppler Ratio For The Prediction Of Adverse Perinatal Outcomes In Late-Onset Fetal Growth Restriction, Sonia Sajja, Onur Turkoglu, Torey Asao, Perry Friedman, Ray Bahado-Singh
Cerebroplacental Doppler Ratio For The Prediction Of Adverse Perinatal Outcomes In Late-Onset Fetal Growth Restriction, Sonia Sajja, Onur Turkoglu, Torey Asao, Perry Friedman, Ray Bahado-Singh
Conference Presentation Abstracts
Objective: Late-onset fetal growth restriction (LO-FGR), defined as onset 3 32 weeks gestation, is the more common subgroup of FGR. The umbilical artery Doppler is usually unaffected. There are no subgroup-specific guidelines for monitoring pregnancies affected by LO-FGR. We compared the utility of the cerebroplacental Doppler ratio (CPR) to the Biophysical Profile (BPP), a widely endorsed FGR monitoring tool, for the prediction of adverse perinatal outcomes (APO). Study Design: This is a retrospective cohort study of LO-FGR, defined as estimated fetal weight < 10th%, from 2013-2018. Using logistic regression analysis, we determined whether low CPR < 5th% and BPP score £ 6 significantly independently predicted the composite APO defined as one or more complications: cord pH < 7.20, 5-minute Apgar score of < 5, operative or cesarean delivery secondary to non-reassuring fetal heart tracing, assisted respiration at birth, NICU admission, and/ or perinatal death. Secondarily, we also evaluated prediction of severe neonatal morbidity (SNM) defined in Table 1 (legend). Results: There were 233 cases of LO-FGR of which 76 (34%) had a low CPR percentile and 28 (13%) had a low BPP score. There were 22 (9.9%) cases with SNM of which 5 (2.1%) had a low CPR percentile and 4 (1.8%) had a low BPP score. A low CPR was associated with a significantly higher rate of individual and composite APO than cases with normal CPR percentile (p < 0.001) [Table 1]. Both a low CPR percentile and a low BPP score significantly predicted APO overall. CPR appeared to be a better predictor of the APO, controlling for gestational age at testing [Table 2]. Only BPP significantly predicted SNM: CPR (OR = 4.64, p = 0.13) and BPP (OR = 4.11, p = 0.038). Conclusion: A low CPR percentile was a significant independent predictor of perinatal complications in LO-FGR, including abnormal fetal heart rate tracing, smaller birthweight percentile, and NICU admission. CPR appeared superior to BPP overall. CPR should be considered as a fetal surveillance tool in LO-FGR.
Artificial Intelligence System Accurately Detects Fetal Ultrasound Findings Suspicious For Major Congenital Heart Defects, Carolyn M. Zelop, Jennifer Lam-Rachlin, Alisa Arunamata, Rajesh Punn, Sarina K. Behera, Matthias Lachaud, Nadine David, Greggory R. Devore, Andrei Rebarber, Sara Garmel
Artificial Intelligence System Accurately Detects Fetal Ultrasound Findings Suspicious For Major Congenital Heart Defects, Carolyn M. Zelop, Jennifer Lam-Rachlin, Alisa Arunamata, Rajesh Punn, Sarina K. Behera, Matthias Lachaud, Nadine David, Greggory R. Devore, Andrei Rebarber, Sara Garmel
Conference Presentation Abstracts
Objective: Prenatal detection of congenital heart defects (CHD) improves patient outcomes. Despite advances in imaging techniques and equipment, prenatal diagnosis remains low. We evaluated the accuracy of an artificial intelligence (AI) system to detect 2nd trimester (2T) ultrasound studies suspicious for CHD. Study Design: The AI system analyzes all grayscale 2D ultrasound cines of a study and detects 8 morphological findings suspicious for CHD. The findings were selected such that most major forms of CHD would feature at least one such finding, and the presence of any of these would flag the study for referral for further examination. We retrospectively …
Maternal Lipidomics For The Accurate Prediction Of Fetal Cyanotic Congenital Heart Defects, Onur Turkoglu, Nadia Ashrafi, Ali Yilmaz, Romana Ashrafi Mimi, Abdullah Khan, Perry Friedman, Ciara Talbot, Stewart Graham, Ray Bahado-Singh
Maternal Lipidomics For The Accurate Prediction Of Fetal Cyanotic Congenital Heart Defects, Onur Turkoglu, Nadia Ashrafi, Ali Yilmaz, Romana Ashrafi Mimi, Abdullah Khan, Perry Friedman, Ciara Talbot, Stewart Graham, Ray Bahado-Singh
Conference Presentation Abstracts
Objective: Late diagnosis of cyanotic congenital heart defects (CCHD) significantly increases newborn morbidity and mortality. However, a significant percentage of CCHD cases remain undetected prenatally. Our objectives were therefore to evaluate the accuracy of maternal serum lipidomic markers for the prenatal detection of CCHD and also to elucidate the pathogenesis of these disorders. Study Design: This prospective case-control study included 40 cases of CHD (22 cyanotic, 18 acyanotic) and 39 unaffected controls. Maternal serum samples were profiled via a combination of Ultra-High-Performance Liquid Chromatography coupled with Mass Spectrometry and Nuclear Magnetic Resonance. The mean of each lipid specie was compared …
How Does 2 Level Cervical Disc Replacement Compare To Single Level?, Pierce Nunley, Brian Perry, Celeste Abjornson, Ashvin Patel, Faheem Sandhu, Armen Khachatryan, Jad Khalil
How Does 2 Level Cervical Disc Replacement Compare To Single Level?, Pierce Nunley, Brian Perry, Celeste Abjornson, Ashvin Patel, Faheem Sandhu, Armen Khachatryan, Jad Khalil
Conference Presentation Abstracts
Introduction: Anterior Cervical Discectomy and Fusion (ACDF) is highly successful at a single level with greater than 90% fusion rates and high patient satisfaction. However, multi-level ACDF surgery, though still successful, has diminishing results with increasing levels. With many Investigational Device Exemption (IDE) clinical trials for the treatment of Symptomatic Cervical Disc Disease (SCDD) at a single level and recent IDE clinical trials for two contiguous levels, these trials offer the opportunity to compare clinical outcomes utilizing the same motion sparing technology mechanisms of action (MOA). The hypothesis is that cervical total disc replacement (cTDR) maintains its clinical benefits from …
Forty-Eight-Month Clinical Outcomes Of Patients Over 60 Years Old In A Prospective, Controlled, Multicenter Study Evaluating Two-Level Cervical Disc Arthroplasty With A Peek-On-Ceramic Artificial Disc, Andrew Park, Richard Guyer, Pierce Nunley, Ashvin Patel, Jad Khalil, James Yue, Arman Khachatryan, K Brandon Strenge, Hyun Bae, Christopher Good, Rick Sasso
Forty-Eight-Month Clinical Outcomes Of Patients Over 60 Years Old In A Prospective, Controlled, Multicenter Study Evaluating Two-Level Cervical Disc Arthroplasty With A Peek-On-Ceramic Artificial Disc, Andrew Park, Richard Guyer, Pierce Nunley, Ashvin Patel, Jad Khalil, James Yue, Arman Khachatryan, K Brandon Strenge, Hyun Bae, Christopher Good, Rick Sasso
Conference Presentation Abstracts
Introduction: Cervical total disc replacement (cTDR) has gained acceptance as a treatment for symptomatic disc degeneration with symptoms of radiculopathy with/without myelopathy. While clinical outcomes of cTDR have consistently been reported to be similar or superior to those of cervical discectomy and fusion, there are limited reports addressing differences related to patient age. The purpose of this study was to compare the 4-year results of two-level PEEKon-ceramic cervical TDR for patients ≥60 years old to those < 60. Materials and Methods: Data were from the prospective Food and Drug Administration (FDA) Investigational Device Exemption (IDE) trial for the Simplify cervical disc. The study included 145 patients who completed 4-year follow-up, of which 124 were < 60 years old at the time of surgery and 21 were ≥60 years. All patients were treated for two-level cervical disc degeneration with radiculopathy and/or myelopathy. Clinical outcome was based on the Neck Disability Index (NDI), neck pain and arm pain intensity scores (10-point scale), and neurologic status. Radiographic measures included flexion/extension (F/E) range of motion (ROM), disc space height, heterotopic ossification, and adjacent-level degeneration based on Kellgren-Lawrence grading. Mean 48-month outcomes for patients ≥60 years old were compared to those of patients < 60. Radiographs were evaluated by an independent lab specializing in image assessment. Results: Of the outcomes reviewed, only one statistically significant difference was detected based on age group. The mean change in F/E ROM from baseline to 48 months at the inferior index level was 3.33° (< 60) and -0.19° (≥60) (p=0.01). At the superior index level, the difference was not significant (1.80° (< 60) vs. 0.12° (≥60); p=0.20). The difference in change in global ROM was also not significant (5.67° (< 60) vs. 0.77° (≥60); p=0.07). Statistically significant differences were not seen for the other outcomes assessed: mean change in NDI, mean change in neck pain, mean change in arm pain. Neurologic status was normal in 93.6% of the < 60 age group and 100.0% of the ≥60 group (p=0.24). The mean change in average disc height from baseline to 48 months was similar in both groups. The distribution of Kellgren-Lawrence grades (none, doubtful, minimal, moderate, and severe) was also similar for each age group for the level above and below the surgical levels (p=0.88 above, p=0.49 below) and the rate of radiographically relevant HO (grade 3 or 4) was comparable between age groups (superior level (p=0.49); inferior level (p=0.20)). Through latest follow-up, there were zero secondary surgical interventions in the ≥60 cohort and 9 in the < 60 cohort. Conclusion: This study found that patients ≥60 years of age who were treated with PEEK-on-ceramic TDR at two levels had comparable clinical and radiographic outcomes to patients < 60 years of age through 4-year follow-up. These results affirm that cervical TDR performs similarly in patients ≥60 versus those < 60, although the small sample size of patients ≥60 years of age is a limitation.
What Is The Difference Of A Decade Of Experience? Comparing Two Multi-Center, Prospective, Randomized Clinical Investigational Device Exemption Trials Of An Approved Tdr At Two Contiguous Levels Of The Cervical Spine, Ashvin Patel, Jad Khalil, Brian Perri, Celeste Abjornson, Feheem Sandhu, Armen Khachatryan, Pierce Nunley
What Is The Difference Of A Decade Of Experience? Comparing Two Multi-Center, Prospective, Randomized Clinical Investigational Device Exemption Trials Of An Approved Tdr At Two Contiguous Levels Of The Cervical Spine, Ashvin Patel, Jad Khalil, Brian Perri, Celeste Abjornson, Feheem Sandhu, Armen Khachatryan, Pierce Nunley
Conference Presentation Abstracts
Introduction: In 2013, the first Investigational Device Exemption (IDE) clinical trial for the treatment of Symptomatic Cervical Disc Disease (SCDD) at two contiguous levels was approved for an unconstrained Total Disc Replacement (cTDR). A decade later, this same device was the control arm of a new IDE trial at 2 levels. Although different investigators, the objective of this analysis was to explore if a decade of knowledge demonstrated a significant improvement in patient outcomes compared to the original trial. Materials and Methods: Both studies were prospective, randomized, multi-center, controlled IDE clinical trials with similar inclusion/exclusion criteria and study designs. The …
Assessing The Impact Of Obesity On Postoperative Outcomes In Rcc Using Machine Learning, Atulya A. Khosla, Manas Pustake, Sufal Chhabra, Yanjia Zhang, Mukesh Roy, Muni Rubens, Venkataraghavan Ramamoorthy, Anshul Saxena, Ishmael A. Jaiyesimi
Assessing The Impact Of Obesity On Postoperative Outcomes In Rcc Using Machine Learning, Atulya A. Khosla, Manas Pustake, Sufal Chhabra, Yanjia Zhang, Mukesh Roy, Muni Rubens, Venkataraghavan Ramamoorthy, Anshul Saxena, Ishmael A. Jaiyesimi
Conference Presentation Abstracts
Introduction Obesity is associated with an increased risk of developing renal cell carcinoma (RCC) but paradoxically correlates with improved outcomes in metastatic cases. Moreover, the data on the relationship between obesity and postoperative outcomes following nephrectomy are inconsistent. Accurate prediction of postoperative outcomes, including complications, 30-day readmissions, and mortality, is essential for improving patient outcomes in surgical procedures. In this study, we utilized ML models to predict such outcomes in RCC patients undergoing nephroureterectomy, radical nephrectomy, partial nephrectomy, and other excision procedures on the kidney using data from the National Surgical Quality Improvement Program (NSQIP; 2016- 2021). Methods A gradient-boosted …
There Is "Thorn" Than Meets The Eye, Zaid Alnabulsi
There Is "Thorn" Than Meets The Eye, Zaid Alnabulsi
Conference Presentation Abstracts
No abstract provided.
Chronic Intestinal Pseudo-Obstruction: A Debilitating Complication Of Scleroderma, Pawan Gyawali
Chronic Intestinal Pseudo-Obstruction: A Debilitating Complication Of Scleroderma, Pawan Gyawali
Conference Presentation Abstracts
No abstract provided.
Myxedema Coma Due To Interrupted Levothyroxine Therapy, Tajuldeen Al Hasani
Myxedema Coma Due To Interrupted Levothyroxine Therapy, Tajuldeen Al Hasani
Conference Presentation Abstracts
No abstract provided.
A Rare Case Of An Immune Checkpoint Inhibitor-Induced Myopericarditis, Morgan Korn
A Rare Case Of An Immune Checkpoint Inhibitor-Induced Myopericarditis, Morgan Korn
Conference Presentation Abstracts
No abstract provided.