Medical Specialties Commons^™

Performa Diagnostik Global Leadership Initiative On Malnutrition (Glim) Dibandingkan Dengan Malnutrition Nutritional Assessment (Mna) Dalam Pengkajian Malnutrisi Pada Pasien Geriatri Di Rawat Inap, Astrine Permata Leoni, Wita Rizki Amelia, Purwita Wijaya Laksmi, Ahmad Syauqy

Jurnal Penyakit Dalam Indonesia

Introduction. As many as 76.6% of patients aged 60 years and above (elderly) are malnourished or at risk of malnutrition based on MNA within the first 48 hours of hospital admission. The prevalence of malnutrition varies widely depending on the population studied, the healthcare setting and the tools used for the assessment. To date, SGA is widely used in the diagnosis of malnutrition for adults and MNA for elderly patients. Recently, experts proposed empirical consensus of GLIM criteria for determining the diagnosis of malnutrition in adults. This study aimed to investigate the diagnostic performance of GLIM criteria as a …

Sensitisasi Alergen Makanan Pada Pasien Kolitis Eosinofilik: Laporan Kasus, Agnes Dina Irene Dorithy Zagoto, Deshinta Putri Mulya, Neneng Ratnasari

Jurnal Penyakit Dalam Indonesia

Eosinophilic colitis is a very rare disease that can occur in the bimodal population (neonates and young adults) with a prevalence was 2.1/100,000 in overall population and 2.3/100,000 in adults. However, only about 0.1% of cases were diagnosed from biopsy results obtained during colonoscopy. The lack of precise histological criteria for the quantity of eosinophils in the colon mucosa creates a distinct challenge in diagnosing eosinophilic colitis. Eosinophilia in the gastrointestinal tract can be mediated by IgE and non-IgE, but non-IgE tends to be dominant in adults. This report discusses about a case of a 64-year-old male with bloody diarrhea …

Penilaian Domain Pengkajian Paripurna Pasien Geriatri (P3g) Sebagai Faktor Yang Berpengaruh Terhadap Kejadian Pneumonia Nosokomial Pada Pasien Usia Lanjut Yang Dirawat Di Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo, Hildebrand Hanoch Victor, Edy Rizal Wahyudi, C. Martin Rumende, C. H. Soejono, A. G. Rooshoeroe, Hamzah Shatri, Leonard Nainggolan, Cosphiadi Irawan

Jurnal Penyakit Dalam Indonesia

Introduction. Nosocomial pneumonia is a lung infection that occurs after the patient is hospitalized for more than 48 hours, without any signs of pulmonary infection at the time of treatment. When compared with young individuals, elderly individuals are more likely to have community-sourced and nosocomial infections with worse outcomes. Comprehensive Geriatric Assessment (CGA) domains are expected to explain the factors that contribute to nosocomial pneumonia in elderly patients. This study aimed to determine the proportion of elderly treated at Dr. Cipto Mangunkusumo National Central General Hospital who experienced nosocomial pneumonia and whether the CGA domains influence the occurrence of nosocomial …

Gambaran Risiko Post-Traumatic Stress Disorder (Ptsd) Pada Penyintas Covid-19 Di Rumah Sakit Universitas Andalas, Sri Wahyuni, Arina Widya Murni, Beni Indra, Rini Gusya Liza, Isnindiah Koerniati, Eldi Sauma

Jurnal Penyakit Dalam Indonesia

Introduction. The COVID-19 pandemic has a negative impact on life where sufferers can experience emotional problems such as despair, deep sadness, helplessness, anxiety, and depressive symptoms. Especially in hospitalized COVID-19 survivors, there are sequelae in the form of anxiety, depression, and Post-traumatic Stress Disorder (PTSD). PTSD experienced by COVID-19 survivors will affect the patient’s quality of life in the future. This study aimed to assess the risk of PTSD in COVID-19 survivors who had been hospitalized at Andalas University Hospital.

Methods. A cross-sectional descriptive study was conducted among COVID-19 survivors aged ≥15 years who had been hospitalized at Andalas University …

Modulasi Mikrobiota Untuk Memperbaiki Laju Filtrasi Glomerulus, Toksin Uremik, Dan Penanda Inflamasi Pada Gagal Ginjal Kronik: Telaah Sistematik Dan Meta-Analisis, Burhan Gunawan, Raymond Sebastian Purwata, Syarif Hidayat, Roy Akur Pandapotan, Jennifer Jennifer

Jurnal Penyakit Dalam Indonesia

Introduction. Dysbiosis microbiota is considered as one of the consequences and impacts of high uremic toxins in patients with Chronic Kidney Disease (CKD), which can lead to an increased risk of progression and mortality. The aim of this systematic review and meta-analysis was to perform quantitative effect of microbiota modulation for estimated Glomerular Filtration Rate (eGFR), uremic toxin (total-p cresyl/total pCS), and inflammatory marker (hs-CRP) outcome among CKD patients.

Methods. Article searches were conducted from PubMed, ScienceDirect, and Cochrane Library data sources from 2010-2022. Assessment of article quality follows the rules of PRISMA (Preferred Reporting Items in Systematic …

Efektivitas Ekstrak Strobilanthes Crispus Terhadap Kadar Glukosa Darah Puasa Dan Pasca Tes Toleransi Glukosa Oral Pada Rattus Norvegicus Diabetes Melitus, Alvin Gunawan, Laura Wihanto, Ari Christy Muliono

Jurnal Penyakit Dalam Indonesia

Introduction. The 2018 Riskesdas data shows that the prevalence of diabetes mellitus is increasing each year. Strobilanthes crispus leaves are known for lowering blood glucose levels. This study aimed to determine the difference in the effectiveness of S. crispus leaves ethanolic extract on fasting blood glucose (FBG) and post-oral glucose tolerance test (OGTT).

Methods. True experimental study using post-test only control group design and Rattus norvegicus as experimental animals. Rattus norvegicus were selected by random sampling which were then divided into 4 groups (K, P1, P2, P3), each group consisted of 5 animals. The animals were subsequently induced with diabetes …

Profilaksis Pasca Paparan Virus Hiv Pada Petugas Kesehatan, Teguh Harjono Karjadi

Jurnal Penyakit Dalam Indonesia

Health workers (HCWs) are prone to get infected by HIV infection when carrying out their duties. The injuries can be caused by needle sticks, sharp objects (scalpels, lancets, or other) that have been exposed to body fluids or splashes of body fluids onto the body’s mucosa (eyes, nose, mouth) and non-intact skin have the potential to transmit the HIV infection. Post-exposure transmission due to contamination of body fluids to health workers can be prevented by providing post-exposure prophylaxis therapy. Post-exposure prophylaxis (PEP) is given as soon as possible and no later than 72 hours after exposure. Prophylaxis is given to …

Vaksinasi Influenza Sebagai Prediktor Terjadinya Kejadian Rawat Inap Akibat Kejadian Kardiovaskular Pada Pasien Dengan Riwayat Penyakit Jantung Koroner: Suatu Laporan Kasus Berbasis Bukti, Sukamto Koesnoe, Alvin Johan, Widhi Dewanta, Nabilla Gita Ekanara, Muhammad Ikrar Hermanadi

Jurnal Penyakit Dalam Indonesia

Influenza is known to worsen cardiovascular events in patients with a history of coronary heart disease. However, the effectiveness of influenza vaccination in reducing hospitalization due to cardiovascular disease is not clearly known. We aim to determine the effect of influenza vaccination on hospitalization rates due to cardiovascular disease in patients with a history of coronary heart disease. Relevant literature was searched on four electronic databases: MEDLINE, EMBASE, SCOPUS, and Cochrane Library, using predetermined keywords. Critical review of the studies was done using the Center of Evidence Based Medicine (CEBM) University of Oxford assessment tool. The search yielded six articles, …

Pemberian Antibiotik Dini Berpengaruh Terhadap Mortalitas Covid-19?, Muchlis Achsan Udji Sofro

Jurnal Penyakit Dalam Indonesia

Coronavirus disease 2019 (COVID-19) merupakan infeksi saluran napas yang diakibatkan oleh severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Data di seluruh dunia sampai akhir Juni 2022 menunjukkan bahwa COVID-19 telah menyebabkan 6,2 juta kematian dengan jumlah 530 juta kasus.

Cutaneous Adverse Drug Reaction Among Hiv-Infected Patients Starting Antituberculosis Treatment, Alvina Widhani, Teguh Harjono Karjadi, Evy Yunihastuti, Desi Salwani, Angga Pramudita, Saut Horas Nababan, Mirna Nurasri Praptini, Prionggo Mondrowinduro

Jurnal Penyakit Dalam Indonesia

Introduction. Treatment of tuberculosis (TB) in HIV patients is complicated due to numerous comorbidities and possible adverse effects. One of which is cutaneous adverse drug reaction (CADR). This adverse event is often difficult to manage because of multiple medications the patients get. The objective of this study was to know the prevalence and risk factors of CADR among HIV-infected patients starting anti-TB treatment. Methods. This retrospective study reviewed data from medical records of new patients at Working Group on AIDS outpatient clinic at Cipto Mangunkusumo Hospital, Indonesia in January 2008-December 2010 that had started anti-TB treatment. Risk factors of CADR …

Determinant Factors Of Cognitive Frailty In Elderly Patients, Valencia Santoso, Rensa Rensa

Jurnal Penyakit Dalam Indonesia

Introduction. Physical frailty and cognitive impairment have a strong relationship and there are differences in factors associated with cognitive frailty. This research aimed to determine the prevalence of cognitive frailty and identify factors associated with cognitive frailty in the elderly population in hospital polyclinic. Methods. A cross-sectional study with secondary data on patients aged ≥60 years in the Internal Medicine Polyclinic of Atma Jaya Hospital, Jakarta, from May 2020 to May 2021. The independent variables of this study were age, cardiovascular disease, type 2 diabetes mellitus, dyslipidemia, risk of malnutrition, risk of depression, and functional status. The alternative criteria by …

Effectiveness Of Garlic Extract (Allium Sativum) To Reduce Level Of Malondialdehyde Serum And Improve Quality Of Life In Patients With Chronic Hemodialysis: A Randomized Double-Blind Placebo-Controlled Trial, Amelia Istiqomah, Zulkhair Ali, Irsan Saleh

Jurnal Penyakit Dalam Indonesia

Introduction. Study reported that malondialdehyde (MDA) levels as an in vivo marker of oxidative stress were increased in patients undergoing hemodialysis. Antioxidants allicin compounds contained in garlic (Allium sativum) are known to have antioxidant activity by inducing antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT) and inhibiting prooxidant enzymes (nitric oxide synthase, xanthine, NADPH oxidase, and cyclooxygenase). This study aimed to investigate the effectiveness of Allium sativum to reduce level of MDA serum and improve quality of life in patients with chronic hemodialysis. Methods. This study was a crossover randomized double-blind placebo-controlled trial. The subjects were 40 chronic kidney …

Effect Of Advance Care Planning On Heart Failure Patients: An Evidence Based Case Report, Hamzah Shatri, Nandika Nurfitria, Dika Sinulingga, Vinandia Irvianita, Edward Faisal, Rudi Putranto, Diah Martina

Jurnal Penyakit Dalam Indonesia

Despite the advances in medical therapy, heart failure remains a disease that requires attention due to the course of the illness; it can lead to unpredictable, progressive, and fatal conditions. Existing therapy aims to improve the condition and prevent disease progression, with a balanced secondary therapy for various conditions that can trigger acute decompensated heart failure. Advances in technology and therapy may increase the prevalence of patients with heart failure, including prolonging the refractory phase of the disease. There are recommendations for advance care planning to support patient therapy and improve the quality of life of patients with heart failure. …

Kecubung Intoxication: A Case Report On A 16-Year-Old Male At Kuningan District, Monica Djaja Saputera, Jessica Djaja Saputera

Jurnal Penyakit Dalam Indonesia

Kecubung (angel’s trumpet) is a plant with hallucinogen effect which contain a tropane alkaloid, which are widely grown in Indonesia and is widely abused by several groups of adolescents aged 18 years in East Nusa Tenggara. Kecubung intoxication is a common case in Indonesia, but rarely reported and hard to make a definitive diagnosis due to lack of the toxicology screening assessment. Besides, an antidote of this case also not available in this country. We present a case of 16-years old male who visited the emergency room with fluctuating level of consciousness accompanied by anxiety, anger, and a visual hallucination. …

Value Of Heart Rate Variability, Neutrophil-Lymphocyte Ratio And Quality Of Life Of Patients With Depressive Symptoms In Acute Myocardial Infarction, Hamzah Shatri, Mizanul Adli, Muhadi Muhadi, Murdani Abdullah, Cosphiadi Irawan, Rudi Putranto, Sukamto Koesnoe, Ika Prasetya Wijaya

Jurnal Penyakit Dalam Indonesia

Introduction. Major depression criteria can be found in more than 20% of coronary heart patients and more than 30% acute coronary syndrome patients have significant depressive symptoms. Several studies have shown that reduction of hearth rate variability (HRV) and enhancement of neutrophil lymphocyte ratio (NLR) can cause enhancement of morbidity and mortality in myocardial infarction patients. On the other hand, depression can cause reduction of HRV, enhancement of NLR and reduction of quality of life. This study aimed to determine differences in HRV, NLR and quality of life between acute myocardial infarction (AMI) patients with depressive symptoms and AMI patients …

Haircare Practice And Dandruff Problems Among Indonesian Medical Students, Jessica Rosemary Wikanto, Lorettha Wijaya, Yunisa Astiarani, Regina Regina

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Dandruff is an understated hair and scalp problem that causes striking social and concentration issues among medical students. Haircare practice among them may or may not be related to the dandruff incident.

Methods: A cross-sectional study was conducted on 74 pre-clinical medical students at Atma Jaya Catholic University of Indonesia. Trained health staff assessed dandruff prevalence by physical examination, and the haircare practice was measured using a questionnaire. Bivariate analysis was utilized to assess the association between haircare practice and dandruff prevalence’s.

Result: Among respondents, 85.1% of them have dandruff. Respondents who shampooed less than five …

Clinicodemographic And Laboratory Characteristics Of Cutaneous Tuberculosis At Tertiary Referral Hospital In West Java, Indonesia, Anisa Sediadini, Hendra Gunawan, Risa Miliawati Nurul Hidayah

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Cutaneous tuberculosis (TB) is a chronic infectious disease affecting the skin caused by Mycobacterium tuberculosis (M. tuberculosis). It constitutes 1–1.5% of extrapulmonary TB, with Indonesia being the third-highest TB burden country worldwide. Cutaneous TB is difficult to diagnose due to its varied presentations. This study aimed to describe the clinicodemographic and laboratory characteristics of cutaneous TB in a tertiary referral hospital in West Java, Indonesia.

Methods: This was a descriptive retrospective cross-sectional study. Data were obtained from the medical record of patients with cutaneous TB in the Tropical Dermatology Clinic of Hasan Sadikin Hospital Bandung, West Java, …

The Difference In Transepidermal Water Loss (Tewl) Values Between Sun-Exposed And Non-Sun-Exposed Skin Among Male Medical Students, Ihsany Arafiasetyanto Prihadi, Endra Yustin Ellistasari, Arie Kusumawardani

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Transepidermal Water Loss (TEWL) is the amount of water released from the human body into the atmosphere through a diffusion process per unit of time. Changes in TEWL indicate impaired skin barrier function. Exposure to ultraviolet light for an extended period can cause photoaging, characterized by rough and dry skin (xerosis cutis). TEWL will increase significantly in the skin exposed to ultraviolet radiation. This study aims to determine the difference in the TEWL values among male medical students in the sun-exposed and non-sun-exposed skin areas.

Methods: An analytical observational cross-sectional study was conducted at the Dermatology and …

Risk Factors For Hiv-Positive Status In Condyloma Acuminata, Izazi Hari Purwoko, Putri Laksmi Karim, Suroso Adi Nugroho, Theresia Toruan, Fitriani .

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Condyloma acuminata (CA) is a sexually transmitted infection (STI) caused by human papillomavirus (HPV), especially types 6 and 11. The number of HPV infections increases in immunosuppressed conditions, such as human immunodeficiency virus (HIV) infection. Risk factors in CA patients such as gender, sexual partner, sexual orientation, and sexual intercourse can increase HIV status.

Methods: This is a descriptive-analytic study with a cohort retrospective design. The subjects are all CA patients who visited the polyclinic STI Dr. Mohammad Hoesin, General Hospital, Palembang, Indonesia, between 2016-2020. The number of CA patients included in the study were 115 patients …

A Case Of Longitudinal Melanonychia In A Child: Benign Or Malignant?, Heffi Anindya Putri, Ennesta Asri, Qaira Anum

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Longitudinal melanonychia (LM) describes a longitudinal brown-to-black band of discoloration affecting a finger, thumb, or toenail. Discoloration of the nails can be a sign of benign or malignant nail disorders. Although nail melanoma rarely occurs in children, health practitioners should be aware of melanonychia. Dermoscopy and histopathology are helpful in the diagnosis.

Case Illustration: A case of LM in a thirteen-year-old girl was reported with a complaint of brownish-black discoloration, sometimes painful, on her right thumb since 1 year ago. She had no history of trauma, nail damage, or bleeding tendency. Dermatological examination found a homogeneous brownish-black …

Seborrheic Keratosis Profile At Dr. Hasan Sadikin Central General Hospital Bandung 2015-2019, Eva Krishna Sutedja, Resti Gradia, Tri Aswila Latifah

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Seborrheic keratosis (SK) is adults’ most prevalent benign skin tumor. SK originates from the proliferation of keratinocyte cells with varying morphology and degree of pigmentation. The lesions often resemble other types of malignancy. There are still many discrepancies in SK in Indonesia; hence, SK needs further understanding. This study aimed to describe the profile of seborrheic keratosis cases based on age, sex, location of lesions, and therapy at Dr. Hasan Sadikin Central General Hospital, Bandung, for five years

Methods: This was a retrospective descriptive study with total sampling. Secondary data were collected from medical records of SK …

Non-Pustular Annular Psoriasis With Signs Of High Disease Activity, Nevi Yasnova, Windy Keumala Budianti, Melody Febriana Andardewi

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Non-pustular annular psoriasis is a rare condition in which a type of plaque psoriasis appears with ring-like lesions and a clearer central appearance. The disease activities in psoriasis may be evaluated clinically. It is essential to provide a more meaningful approach to treatment management.

Case illustration: A 33-year-old woman complained of a one-year history of multiple erythematous, scaly, and annular plaques with central clearing. Some lesions were surrounded by discrete pinpoint papules on several parts of her body. The lesions worsened during seven weeks of topical and systemic therapy.

Discussion: Psoriasis is a chronic, multisystem inflammatory …

Association Between Early Antibiotic Administration And In-Hospital Mortality In Moderate And Severe Covid-19 Patients, Lie Khie Chen, Jason Nathanael, Sharifah Shakinah, Adeline Pasaribu, Robert Sinto, Leonard Nainggolan, Adityo Susilo

Jurnal Penyakit Dalam Indonesia

Introduction. Patients with moderate and severe COVID-19 generally receive antibiotic therapy with consideration of the possibility of co-infection or secondary bacterial infection which clinically is difficult to distinguish from COVID-19 symptoms. Overuse of antibiotics can lead to an increased risk of bacterial resistance to antibiotics which is associated with poor outcomes in COVID-19 patients. This study aimed to assess the effect of early antibiotic administration on mortality in moderate and severe COVID-19 patients. Methods. An observational study with a retrospective cohort design was conducted at Dr. Cipto Mangunkusumo Hospital. Data were obtained from medical records of patients admitted from March …

Second-Line Therapy Tyrosine Kinase Inhibitor For Chronic Phase Chronic Myeloid Leukemia Resistant To Imatinib, Chici Pratiwi, Wulyo Rajabto

Jurnal Penyakit Dalam Indonesia

Since the era of tyrosine kinase inhibitor (TKI) therapy, there has been an increase in the median survival of chronic myeloid leukemia. Nevertheless, nowadays there were several cases of chronic myeloid leukemia that are resistant to the first-line TKIs, so that several second-line TKIs were introduced. Assessment of the therapeutic response was performed using a complete peripheral blood examination, bone marrow aspiration cytogenetic examination, and quantitative BCR-ABL examination. The treatment failure criteria were applied based on the ELN criteria. In selecting the second line TKI should be based on the results of mutation analysis and consider the safety profile of …

Pengaruh Diaphragmatic Breathing Dan Endurance Exercise Terhdap Peningkatan Kapasitas Kardiorespirasi Pada Pasien Hospital-Acquired Pneumonia, Alifia Azzahra, Annisya Puspitarani, Zahra Sativani, Riza Pahlawi

Jurnal Fisioterapi Terapan Indonesia

The purpose of this case study is to determine the effect of diaphragmatic breathing and endurance exercise in hospital-acquired pneumonia (HAP) cases. HAP is a nosocomial pneumonia that occurs 48 hours or more after the patient is admitted to the hospital, without any signs of pulmonary infection at the time of initial treatment. The existence of clinical manifestations that appear, patients with HAP tend to avoid physical activity which can decrease the functional capacity of the respiratory system and have an impact on decreasing endurance. Diaphragmatic breathing exercise is thought to be able to help reduce shortness of breath, reduce …

Pengaruh Diaphragmatic Breathing Dan Endurance Exercise Terhadap Peningkatan Kapasitas Kardiorespirasi Pada Pasien Hospital-Acquired Pneumonia, Alifia Azzahra, Annisya Puspitarani, Zahra Sativani, Riza Pahlawi

Jurnal Fisioterapi Terapan Indonesia

The purpose of this case study is to determine the effect of diaphragmatic breathing and endurance exercise in hospital-acquired pneumonia (HAP). Nosocomial pneumonia that occurs in 48 hours or more after the patient admitted to the hospital, without any signs of pulmonary infection. The existence of clinical manifestations that appear, patients with HAP tend to avoid physical activity which can decrease the functional capacity of the respiratory system and have an impact on decreasing endurance. Diaphragmatic breathing exercise is thought to be able to help reduce shortness of breath, reduce the work of the accessory muscles of breathing, improve breathing …

Clinicodemographic Characteristics Of Cutaneous Larva Migrans: A 10-Year Study In Tertiary Referral Hospital-West Java, Indonesia, Tuesi Fredella Avissa, Hendra Gunawan, Risa Miliawati Nurul Hidayah

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Cutaneous larva migrans (CLM) is the most common helminthic dermatosis caused by animal hookworm, commonly reported in tropical and subtropical regions. Most studies are on travellers returning from endemic areas, paradoxically very few reports in endemic countries, including Indonesia, where they mostly take place. This study aimed to describe the demographic and clinical characteristics of CLM patients for 10 years in a tertiary referral hospital in West Java, Indonesia.

Methods: This was a descriptive retrospective cross-sectional study. The data were obtained from the medical record of patients who was diagnosed as CLM in Tropical Dermatology Clinic Hasan …

Correlation Between Serum 25 Hydroxy-Vitamin D Levels And The Worst Pain Intensity In Postherpetic Neuralgia, Wizar Putri Mellaratna, Nelva K. Jusuf, Ariyati Yosi

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Postherpetic neuralgia (PHN) is persistent pain in the affected dermatome that occurs more than three months after the eruption of the herpes zoster has disappeared. Vitamin D has a role in Schwann cell regeneration and stimulates the release of nerve growth factors.

Methods: Blood sampling was performed to test serum 25(OH)D levels. Patients filled out their worst pain intensity using the Zoster Brief Pain Inventory questionnaire. The score was reported in Likert score (0-10), 0 indicating no pain and 10 indicating the most severe pain. Spearman correlation test was used, and p 0.05) and PHN durations (p …

Torch Re-Activation Concomitant With Drug-Induced Hypersensitivity Syndrome Shows Erythema Multiforme-Like And Vasculitis Clinical Features, Windy Keumala Budianti, Rahadi Rihatmadja, Izzah Aulia, Isaak Effendy

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Drug-induced hypersensitivity syndrome (DIHS) can be associated with cytomegalovirus (CMV) infection, besides induced by drugs. We report a case of DIHS with prolonged atypical clinical features and vasculitis precipitated by drug allergy, CMV, and other viral infections.

Case illustration: A 54-year-old female presented with generalized follicular erythematous papules and waxy palmoplantar keratoderma since one month before admission. The symptoms started as a purpuric lesion on the upper extremities, spreading as erythematous papules on the trunk with facial edema, accompanied by fever and chronic cough. She had been previously treated with ambroxol and cephalosporin. Cutaneous drug allergy reaction …

Association Of Smoking With Total Oxidant And Antioxidant Levels In Breast Milk, Nesibe Yildiz, Adnan Yilmaz

Makara Journal of Health Research

Background: Breast milk is a natural food that contains all the fluids, energy, and nutrients necessary for the optimum growth and development of newborns. Smoking is a public health problem that has harmful effects on the mother and baby. This study aimed to examine the association of exposure to smoking with total oxidant status (TOS) and total antioxidant status (TAS) in breast milk.

Methods: Healthy mothers without any health problems during their pregnancy and lactation periods were selected as subjects. Eighty-eight milk samples (44 in the smoking group and 44 in the nonsmoking group) were examined. TOS and …