Medical Specialties Commons^™

The Effects Of A Trauma-Informed Care Training Program On Mental Health Professionals Knowledge, Skills, And Attitudes With The Smi, Angelina Pelletier

PCOM Psychology Dissertations

Trauma has been found to be highly prevalent among individuals diagnosed with SMIs. Mental health professionals have been reported to misdiagnose or avoid addressing trauma in this population. There is a need to provide information about trauma and to foster awareness among mental health professionals who are treating individuals diagnosed with SMIs. With a TIC approach, operating from a recovery-oriented philosophy, there have been interventions created to address trauma and SMIs with the aim of developing awareness about trauma and the impact it may have on someone’s life. With these factors in mind, mental health professionals should be competent in …

Is Non-Nutritive Sucking An Effective Method Of Providing Analgesia To Newborns Undergoing Painful Procedures?, Eric B. Hooper

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: “The objective of this selective EBM review is to determine whether or not nonnutritive sucking is an effective method of providing analgesia to infants undergoing painful procedures.”

STUDY DESIGN: A systematic review of three blinded randomized-controlled trials (RCT’s), published from 2011 to 2013. All were published in English, one of which was translated from its original Spanish version to an English publication. DATA

SOURCES: Three RCT’s were found using the PubMed database and all were published in peer-reviewed journals.

OUTCOMES MEASURED: The incidence and severity of pain were measured during procedures using the Premature Infant Pain Profile (PIPP) and/or …

Is Brimonidine Tartrate Gel .5% Effective In Reducing Facial Erythema Of Rosacea?, Meeta Aggarwal

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective Evidence Based Medicine (EBM) review is to determine whether or not “Is Brimonidine Tartrate gel 0.5% effective in reducing facial erythema of Rosacea?”

STUDY DESIGN: Review of two randomized controlled trials (RCT), and one 1-year longitudinal open-label study.

DATA SOURCES: All studies were published in peer-reviewed journals found via the use of PubMed or Medline.

OUTCOMES MEASURED: Patients were divided into two groups: those who received the Brimonidine Tartrate gel and those who received the vehicle (placebo) gel. Efficacy of Brimonidine tartrate gel was compared to the efficacy of the vehicle gel. Outcomes were …

Medical Interns', Residents' And Attending Physicians' Attitudes Towards Integrative Medicine And Recommended Treatments For Patients With Psoriasis, Jennifer L. Pacyon

PCOM Psychology Dissertations

Background: Psoriasis is a multifactorial disease that effect approximately 7.5 million Americans. There are a variety of traditional treatments for psoriasis (e.g. topical medications, biologics) that for many, are effective in combating the disease. However, traditional treatments often have aversive side effects and may not be appropriate for every patient (e.g. pregnant women). Additionally, the efficacy of these medications are variable leaving some looking for adjunctive treatment options. There is increasing evidence to support the use of adjunctive treatments for psoriatic patients (e.g. psychotherapy, mindfulness). However, research is variable in regards to medical professionals’ attitudes towards integrative medicine (IM) as …

Glanzmann's Thrombasthenia: Pathogenesis, Diagnosis, And Current And Emerging Treatment Options, Tia Solh, Ashley Botsford, Melhem Solh

PCOM Scholarly Works

Glanzmann’s thrombasthenia (GT) is a genetic platelet surface receptor disorder of GPIIb/IIIa (ITG αIIbβ3), either qualitative or quantitative, which results in faulty platelet aggregation and diminished clot retraction. Spontaneous mucocutaneous bleeding is common and can lead to fatal bleeding episodes. Control and prevention of bleeding among patients with GT is imperative, and remains challenging. Local measures, including anti-fibrinolytic therapy, with or without platelet transfusions, used to be the mainstay of therapy. However, in recent years the use of recombinant factor VIIa (rFVIIa) has increased significantly, with excellent response rates in treating and preventing hemorrhage among GT patients. Gene therapy and …

The Effect Of Osteopathic Manipulative Treatment On Length Of Stay In Posterolateral Postthoracotomy Patients: A Retrospective Case Note Study, Regina K. Fleming, Karen T. Snyder, Kent J. Blanke, Jane C. Johnson

PCOM Scholarly Works

Objective

This study retrospectively evaluated the effect of OMT on length of stay (LOS) in hospitalized posterolateral postthoracotomy patients.

Methods

Inpatient medical records of patients who received posterolateral thoracotomies with lung resection between 1998 and 2011 were reviewed for demographic data, LOS, thoracotomy surgery data, consultation data excluding osteopathic manipulative medicine, discharge data, and osteopathic manipulative medicine consultation data.

Results

Thirty-eight patients received posterolateral thoracotomies with lung resection; 23 patients received OMT and 15 did not. The mean (standard deviation) LOS was 11.0 (6.8) days (range, 5–29 days) for those who received OMT and 10.4 (5.5) days (range, 3–22 days) …

Funding And Other Resources For Beginning Researchers, Jane Z. Dumsha, David Yens, Grace Brannan

PCOM Scholarly Works

Despite the fact that osteopathic research is essential for the continued advancement of our profession, such research is lacking. One barrier is the attainment of funding resources to launch and continue quality research studies. In the present article, the authors outline resources for the early stages of research and provide guidance for grant proposal preparation, if it is determined that external funding is needed. Free and low-cost resources for obtaining preliminary data and sources of external funds are described. An overview of grant writing and information on where to obtain training is presented. Information on proposal writing basics, tips to …

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 2015), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 2015 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Message from the President
• PCOM Updates
• Development News
• Institutional Announcement: Farewell to Paul W. McGloin, CPA, LLD (Hon.)
• Institutional Heritage: Founders’ Day 2015
• Feature: The Healing Touch – Health Advocacy without Borders
• Bringing Hope and Care to Ukrainians – Zenia Chernyk, DO ’77
• Helping Victims of Human Trafficking in India – Winson T. George, PhD, DO ’09
• Hands-on in Haiti – Shelly Chvotzkin, DO ’02
• Class Notes
• My Turn

2015 Founders' Day, Philadelphia College Of Osteopathic Medicine

Founders Day Programs

The 2015 Founders Day OJ Snyder Memorial Medal recipients were Oliver Bullock DO '78 and Joseph Dieterle DO '70. The Philadelphia Campus Mason W Pressly Memorial Medal Recipient was Valerie Moore (DO '15). The Georgia campus Mason W Pressly Memorial Medal Recipient was Lauren Smith, (DO '16)

Synapsis: Georgia Campus (2015), Philadelphia College Of Osteopathic Medicine

All Yearbooks

The yearbook includes Class Officers, American Academy of Osteopathy Undergraduate Teaching Fellows, In Memory of Anne Yi Chong, Orientation, Formals, Halloween Party, Student Clubs, Casino Night, Cadaver Ceremony, Student Fun Day, Words of Wisdom.

Synapsis: Philadelphia Campus 2015, Philadelphia College Of Osteopathic Medicine

All Yearbooks

No abstract provided.

A Qualitative Study Of How Children Experience And Live With Long Qt Syndrome, Patrick Mcelwaine

PCOM Psychology Dissertations

Long QT syndrome (LQTS) is an inherited and potentially fatal disorder affecting approximately 1 in 2,000 people. Children often experience anxiety and a sense of loss of control as they try to manage the medical, social, and psychological stress that accompanies being diagnosed with LQTS. The present study utilized a qualitative research design to examine how children experience and live with long QT syndrome. Semistructured interviews were conducted with eight children between the ages of 7 to 12 who were diagnosed with LQTS. This period in a child’s life is very important for developing social skills and self-esteem as peers …

The Influence Of Positive And Negative Death Attitudes On Medical Students' Empathy And Attitudes Toward End-Of-Life Care, Elizabeth Palumbo

PCOM Psychology Dissertations

This quantitative study employed a cross-sectional survey research design in order to examine the relationships between medical students’ death attitudes, empathy, and attitudes toward end-of-life care. The participants were 206 medical students currently enrolled in the Doctor of Osteopathic Medicine program at the Philadelphia College of Osteopathic Medicine, Philadelphia campus. Results indicated that there were no significant differences in the level of empathy between medical students who held strong positive death attitudes and medical students with strong negative death attitudes. However, results indicated that significant differences existed in attitudes toward end-of-life care between medical students who held strong positive death …

The Psychometric Properties Of The Professionalism Assessment Rating Scale, Jennifer K. Olivetti

PCOM Psychology Dissertations

The issue of professionalism in the training of medical students has become a major focus within the field of medical education. For years, the Philadelphia College of Osteopathic Medicine (PCOM) has measured the quality of osteopathic medical students (DO students) interpersonal and communication skills through SP (SP) encounters in which SPs rate the DO students relative to eight criteria (items) which, in aggregate, are known as the Professionalism Assessment Rating Scale (PARS). These criteria are linked in the literature to patient outcomes, patient adherence, patient satisfaction, and malpractice. This study investigated the psychometric properties of the PARS, based on data …

Neurocognitive Patterns, Symptom Clusters, And Premorbid Factors That Predict Protracted Recovery From Concussion In Females, Sarah Pulaski

PCOM Psychology Dissertations

Concussion is an increasingly diagnosed injury that affects individuals of all ages. Although the underlying cause is unknown, research has demonstrated that females who sustain a concussion experience longer recoveries. Existing research has documented a relationship between age, gender, post-concussive headache and mental health conditions, and recovery; however, limited research has investigated the relationship between premorbid clinical variables and recovery. Research on post-injury neurocognitive declines and recovery has also demonstrated varied findings. Moreover, dizziness has been identified as significantly predictive of prolonged recovery, but no studies have investigated the effect of premorbid headache conditions on the development of dizziness. The …

An Analysis Of Cognitive Factors In School-Aged Children With Emotional Disturbance And Adhd Using The Wisc-Iv, Maria Fragnito Maddalo

PCOM Psychology Dissertations

Children with Emotional Disturbance and ADHD demonstrate social, emotional, and behavioral symptoms that present many challenges for School Psychologists because of differences between each student’s individual needs. A high level of comorbidity exists for these children with internalizing and externalizing symptoms. Little is known about neurocognitive factors as they relate to ED versus ADHD. The current study examined the cognitive profiles of a total of 58 children with ED versus ADHD, using the Wechsler Intelligence Scale for Children, Fourth Edition (WISC-IV). Index scores that were examined included Verbal Comprehension, Perceptual Reasoning, Working Memory, and Processing Speed. The groups were compared …

Adhd Versus Ptsd In Preschool-Aged Children: Implications For Misdiagnosis, Klaudette D. Stewart

PCOM Psychology Dissertations

Attention Deficit Hyperactivity Disorder (ADHD) has been one of the most diagnosed disorders in children since it was included in the Diagnostic and Statistical Manual of Mental Disorders−III (DSM−III) in 1980. The number of children who have been diagnosed since that time has grown significantly, raising concerns about the overwhelming number of young children being diagnosed and prescribed medication. According to the literature, young children are diagnosed at a higher rate by pediatric primary care physicians (PCPs) than clinical child psychologists (CCPs) because they are taken to a PCP’s office by a parent, rather than referred from a school environment, …

A Combined Therapeutic Regimen Of Buspirone And Environmental Enrichment Is More Efficacrious Than Either Alone In Enhancing Spatial Learning In Brain-Injured Rats, Christina M. Monaco, Kory M. Gebhardt, Sarah M. Chlebowski, Kaitlyn E. Shaw, Jeffrey P. Cheng

PCOM Scholarly Works

Abstract Buspirone, a 5-HT1A receptor agonist, and environmental enrichment (EE) enhance cognition and reduce histopathology after traumatic brain injury (TBI) in adult rats, but have not been fully evaluated after pediatric TBI, which is the leading cause of death in children. Hence, the aims of this study were to assess the efficacy of buspirone alone (Experiment 1) and in combination with EE (Experiment 2) in TBI postnatal day-17 male rats. The hypothesis was that both therapies would confer cognitive and histological benefits when provided singly, but their combination would be more efficacious. Anesthetized rats received a cortical impact or sham …

Detection Of Bacterial Antigens And Alzheimer's Disease-Like Pathology In The Central Nervous System Of Balb/C Mice Following Intranasal Infection With A Laboratory Isolate Of Chlamydia Pneumoniae, C. Scott Little Phd, Timothy A. Joyce, Christine Hammond, Hazem Matta, David Cahn, Denah Appelt, Brian J. Balin Phd

PCOM Scholarly Works

Pathology consistent with that observed in Alzheimer’s disease (AD) has previously been documented following intranasal infection of normal wild-type mice with Chlamydia pneumoniae (Cpn) isolated from an AD brain (96-41). In the current study, BALB/c mice were intranasally infected with a laboratory strain of Cpn, AR-39, and brain and olfactory bulbs were obtained at 1-4 months post-infection (pi). Immunohistochemistry for amyloid beta or Cpn antigens was performed on sections from brains of infected or mock-infected mice. Chlamydia-specific immunolabeling was identified in olfactory bulb tissues and in cerebrum of AR-39 infected mice. The Cpn specific labeling was most prominent at 1 …

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 2014), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 2014 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Message from the President
• PCOM Updates
• Commencement 2014
• Development News
• Considerations for Healthcare Education
• Diversity and Healthcare Disparities: Remembering the Children
• Instructional Strategies in Continuity Care Education
• Competency-based Assessment: Practicing Emergency Care from the Start
• Health Information Technology Advances Innovative Clinical Teaching Model
• Curbing Healthcare Provider Shortages in the South with New Residency Programs
• Class Notes
• Reunion Weekend
• In Memoriam
• My Turn Essay

Insulin Pump Class: Back To The Basics Of Pump Therapy, Sara Wilson Reece, Cheryl Williams

Research Day

Insulin pump therapy is a common mechanism for insulin delivery in Type 1 diabetes mellitus as well as in some patients with Type 2 diabetes mellitus. At the Longstreet Clinic, approximately 3% of patients on insulin therapy utilize insulin pumps. After several patients on insulin pump therapy experienced severe hypoglycemic episodes while driving, the need for review of insulin pump survival skills were identified. The insulin pump class which was conducted in a small group setting reviewed all of the necessary survival skills for effective insulin pump therapy. Pre- and post-class hemoglobin A1c values and emergency room visits as well …

Mitoquinone (Mitoq) Exerts Antioxidant Effects Independent Of Mitochondrial Targeted Effects In Phorbol-12-Myristate-13-Acetate (Pma) Or N-Formyl-L-Methiony-L-Leucyl-L-Phenylalanine (Fmlp) Stimulated Polymorphonuclear Leukocyte (Pmn) Superoxide (So) Release, Matthew Lepera, D. Pesikan, J. Voeun, Kerry-Anne Perkins, Qian Chen, Robert J. Barsotti, Lindon H. Young

Research Day

MitoQ is a mitochondrial-targeted coenzyme Q antioxidant analog that dose-dependently restored cardiac function and reduced infarct size in isolated perfused rat hearts subjected to ischemia reperfusion (I/R). Moreover, mitoQ also dose-dependently attenuated PMA stimulated PMN superoxide (SO) release at the same concentration (10uM) as the cardioprotective dose. NADPH oxidase is the principle source of PMN SO release. We speculate that mitoQ may exert antioxidant effects independent of the mitochondria. Therefore, we hypothesized that inhibition of mitoQ on PMN-SO release will be similar as other coenzyme Q analogs: coenzyme Q1 and decylubiquinone without affecting cell viability. SO release was measured spectrophotometrically …

Gp91ds-Tat, A Selective Nadph Oxidase Peptide Inhibitor, Increases Blood Nitric Oxide (No) Bioavailability In Bind Limb Ischemia And Reperfusion (I/R), Sydney Walker, Tyler Galbreath, Qian Chen, Robert J. Barsotti, H. Patel, William Chau, Lindon H. Young

Research Day

I/R injury induces cell death and organ dysfunction in part due to a burst of reactive oxygen species that occurs upon the reintroduction of oxygen into the ischemic area, leading to endothelial dysfunction: decreased blood NO and increased hydrogen peroxide (H2O2 ) levels. We’ve previously shown in isolated rat hearts subjected to I/R injury, gp91ds-tat attenuated cardiac contractile dysfunction and reduced infarct size compared to controls presumably by the inhibition of NADPH oxidase induced superoxide release. Superoxide can quench NO via the formation of peroxynitrite and also be converted to H2O2 in blood. We attempted to confirm this hypothesis using …

Anterior Cervical Foraminotomy: Short Term Outcomes In Patients With Isolated Cervical Radiculopathy, Howard Eisenbrock, Mark Rivkin, Amir R. Dehdashti

Research Day

Intro: Anterior cervical foraminotomy (ACF) is a novel approach involving direct decompression of nerve from an offending agent without fusion. Historically, several anterior and posterior approaches were utilized to treat cervical radiculopathy. Anterior cervical discectomy necessitates fusion and is subject to adjacent segment disease as well as loss of ROM. Posterior laminoforaminotomy seldom allows for removal of disc fragment and is associated with higher postoperative pain.

Methods: Between May 2010 and March 2013, 16 patients with one or two level cervical spondylosis with radiculopathy without myelopathy who failed conservative therapies such as anti-inflammatory medications, physical therapy or injections underwent anterior …

Kyphotic Progression After Thoracolumbar Burst Fractures Treated Conservatively, With Mis, Or Via Open Approach, Mark Rivkin, Howard Eisenbrock

Research Day

Management of thoracolumbar burst fractures (AO A3) without neurological deficit is subject to debate in the literature. While TLICS provides guidance for injuries necessitating intervention, it makes little mention of best surgical approaches. Furthermore, intact patients with suspected posterior ligamentous complex injury (TLICS 4) compose an additional level of management uncertainty. Present study examined outcomes for TL burst fractures in neurologically intact patients with suspected disruption of the PLC treated with bracing, MIS, or open fixation and fusion.

Cyclic Nucleotide-Dependent Phosphorylation Regulates Bk-Ca Channel Activity In Human Coronary Artery Smooth Muscle Cells, Raeonda Williams

PCOM Biomedical Studies Student Scholarship

Cardiovascular diseases (CVD) can induce dysfunction in organ systems by attenuating normal blood flow. Gonadal steroids are vasoactive hormones, but their role in contributing to cardiovascular function remains controversial. We have demonstrated that gonadal steroids can relax coronary arteries by opening the large-conductance, calcium- and voltage-activated potassium (BKca) channel in smooth muscle cells by increasing cyclic nucleotide levels; however, the signaling pathways involved remain to be elucidated. The purpose of this study was to identify how phosphorylation (via cAMP- and cGMP-dependent protein kinases) I dephosphorylation (via phosphoprotein phosphatase 2A, PP2A) regulates BKca channel activity in human coronary artery smooth muscle …

2014 Founders' Day, Philadelphia College Of Osteopathic Medicine

Founders Day Programs

The 2014 Founders Day OJ Snyder Memorial Medal recipient was Matthew Schure, PhD. The Philadelphia Campus Mason W Pressly Memorial Medal Recipient was Matthew Spiecher (DO '14). The Georgia campus Mason W Pressly Memorial Medal Recipient was Jason Milton, (DO '14) PharmD, MBA

Catalog (2014-2015), Philadelphia College Of Osteopathic Medicine

Catalogs

A snapshot of the PCOM curriculum through the decades.

Immediate Return To Ambulation And Improved Functional Capacity For Rehabilition In Complex Regional Pain Syndrome Following Early Implantation Of A Spinal Cord Stimulation System, Brandon Jesse Goff, Jeremy Wingseng Naber, John Patrick Mccallin, Edward Michael Lopez, Kevin Brant Guthmiller, Karl Alan Lautenschlager, Tristan Toll Lai, Dean Harry Hommer, Gonzalez Raul Marin

PCOM Scholarly Works

Complex regional pain syndrome (CRPS) is a neuropathic pain condition that is characterized by vasomotor, sensory, sudomotor, and motor symptoms. Spinal cord stimulation (SCS) has been successfully utilized for the treatment of pain refractory to conventional therapies. We present a case of a previously highly functioning 54-year-old female who developed a rarely reported case of idiopathic CRPS of the right ankle which spontaneously occurred four months after an uncomplicated anterior cervical disc fusion. This condition resulted in severe pain and functional impairment that was unresponsive to pharmacological management. The patient's rehabilitation was severely stymied by her excruciating pain. However, with …

Digest Of The Philadelphia College Of Osteopathic Medicine (Summer 2014), Philadelphia College Of Osteopathic Medicine

Digest

The Summer 2014 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Message from the President
• PCOM Updates
• Development News
• Institutional Advancement: Gifting the Optimum in Simulation
• Technology for Skills Training and Competency Assessment
• Institutional Memory: Remembering Herbert Lotman, LLD (Hon.)
• Institutional Heritage: Founders’ Day 2014
• Institutional Feature: A Time of Transition
• With Gratitude . . .
• Reflection about Dr. Schure: Collegial Harmony
• Reflection about Dr. Schure: Doctoring the Doctor
• Reflection about Dr. Schure: Legacy in the South
• Reflection about Dr. Schure: Seeds Planted Are Bearing Fruit
• PCOM Welcomes Jay S. Feldstein, DO ’81, …