Open Access. Powered by Scholars. Published by Universities.®

Medical Specialties Commons™

Open Access. Powered by Scholars. Published by Universities.®

Corewell Health

Articles 661 - 690 of 939

Full-Text Articles in Medical Specialties

Elimination Of Postoperative Narcotics In Infant Robotic Pyeloplasty Using Caudal Anesthesia And A Non-Narcotic Pain Pathway, Kwesi Asantey, Kristen Meier, Zachary Rollins, Andrew B. Banooni, Zachary J. Liss May 2022

Elimination Of Postoperative Narcotics In Infant Robotic Pyeloplasty Using Caudal Anesthesia And A Non-Narcotic Pain Pathway, Kwesi Asantey, Kristen Meier, Zachary Rollins, Andrew B. Banooni, Zachary J. Liss

Posters

INTRODUCTION
Research suggests that narcotic pain medications are dramatically overprescribed. We hypothesize that narcotics are unnecessary in the majority of infants for postoperative pain control. In this series, we report our experience combining caudal blocks with a non-narcotic postoperative pathway as a means of completely eliminating postoperative narcotics following infant robotic pyeloplasty.

Go to article

Cardiorespiratory, Hemodynamic, And Perceived Exertion Responses To Seated Chair Exercise, Ryan Khemraj, Cristian Solano, Neesirg Patel, Roger Sacks May 2022

Cardiorespiratory, Hemodynamic, And Perceived Exertion Responses To Seated Chair Exercise, Ryan Khemraj, Cristian Solano, Neesirg Patel, Roger Sacks

Posters

INTRODUCTION
The increasing prevalence of cardiovascular disease (CVD) and its sequelae in the United States population has led to escalating health care expenditures. To favorably modify cardiovascular outcomes, exercise physiologists have developed varied exercise programs that are associated with mortality reduction, symptom relief, improved exercise tolerance, favorable risk factor modification and improved psychosocial well-being. For patients with significant disability and deconditioning, chair-based exercise may provide an alternative method of achieving the relative cardioprotective benefits of traditional exercise.

Go to article

Relatedness Of Urinary Escherichia Coli Strains And Connection Between Strain Type And Clinical Presentation, Anet Szatkowski, Venkathesh Bai, Matthew D. Sims May 2022

Relatedness Of Urinary Escherichia Coli Strains And Connection Between Strain Type And Clinical Presentation, Anet Szatkowski, Venkathesh Bai, Matthew D. Sims

Posters

INTRODUCTION
Urine is often not a sterile body fluid. When bacteria in the urine cause symptoms it is by definition a urinary tract infection (UTI). The specific symptoms will point toward a bladder infection (cystitis) or a kidney infection (pyelonephritis). Presence of bacteria in the urine without symptoms defines asymptomatic bacteriuria (AB). Despite requiring symptoms to diagnose a UTI, often AB is misdiagnosed as a UTI and treated with antibiotics when none are needed. Escherichia coli is the most common cause of UTIs accounting for 80-90% of community-acquired UTIs and 30-50% of nosocomial UTIs. The goals of this study are …

Go to article

Quality Improvement Study On Human Papilloma Virus (Hpv) Vaccination Uptake In Hiv Patients, Hassan Akram, Paul Johnson, Trini A Mathew May 2022

Quality Improvement Study On Human Papilloma Virus (Hpv) Vaccination Uptake In Hiv Patients, Hassan Akram, Paul Johnson, Trini A Mathew

Posters

INTRODUCTION HPV is strongly associated with cervical cancer and cancers of vagina, vulva, penis, anus, rectum. In 2019, WHO identified vaccine hesitancy as top 10 global threats and planned to increase the HPV vaccine coverage. In June 2019 Advisory Committee on Immunization Practices (ACIP) in the US recommended shared clinical decision-making regarding HPV vaccinations in adults aged 26 through 45 years. The goal of this project is to evaluate the uptake of HPV vaccination and challenges in the HIV patients at Beaumont Hospital.

Go to article

Resistance In Gram-Negative Bacteria In The Pediatric Patient Population By Age And Sex, Benjamin Malamet, Matthew Sims May 2022

Resistance In Gram-Negative Bacteria In The Pediatric Patient Population By Age And Sex, Benjamin Malamet, Matthew Sims

Posters

INTRODUCTION
Previous research within the Beaumont Infectious Diseases Research Program found an increase in antibiotic resistance in adult males versus females. Furthermore, there is a peak in resistance in 18-29-year-old males, not seen in females. The origin of this early peak of antibiotic resistance in adults is unclear. This study examines these trends in the pediatric patient population.

Go to article

Dietary Supplement Use Among Brca1/2 Mutation Carriers, Ryan Rogers, Tara Ramgarajan, Virginia Uhley, Kristina Ivan, Dana Zakalik May 2022

Dietary Supplement Use Among Brca1/2 Mutation Carriers, Ryan Rogers, Tara Ramgarajan, Virginia Uhley, Kristina Ivan, Dana Zakalik

Posters

INTRODUCTION
Women who carry BRCA1/2 mutations are at significantly increased risk of breast, ovarian, pancreatic and other cancer. Little is known regarding the use of dietary supplements among women harboring BRCA1/2 mutations. This study aims to characterize the utilization of and attitudes toward dietary supplement use in women who carry BRCA1/2 mutations.

Go to article

Patient Perceptions Of Their Health Care Teams And Preferences For Making Decisions Regarding Medical Care, Veronica F. Williams, Nelia Afonso May 2022

Patient Perceptions Of Their Health Care Teams And Preferences For Making Decisions Regarding Medical Care, Veronica F. Williams, Nelia Afonso

Posters

INTRODUCTION
Beaumont Hospital values patient and family-centered care, but a clear understanding of how patients perceive their health care teams and prefer to make decisions regarding their medical treatment have not been well-described. It is necessary to understand patients’ preferences regarding various factors that impact their medical care in order to foster an effective health care environment. The primary goal of this study is to determine how patients’ care teams impact the ways in which they make decisions regarding their medical treatment. A secondary goal is to determine the individuals, both inside and outside of the health care setting, that …

Go to article

Association Of Gut Metabolomic Biomarkers With Sleeve Gastrectomy Weight-Loss Outcomes, Pamela Spicer, Wendy Miller, Kathryn Ziegler, Stewart Graham May 2022

Association Of Gut Metabolomic Biomarkers With Sleeve Gastrectomy Weight-Loss Outcomes, Pamela Spicer, Wendy Miller, Kathryn Ziegler, Stewart Graham

Posters

INTRODUCTION
Obesity is a prevalent health challenge with high morbidity and many associated chronic diseases. Sleeve gastrectomy is currently the predominant intervention for obesity. However, weight loss results are variable. The mechanisms and factors influencing this variability are not well understood. We evaluated the correlation of metabolomic biomarkers with weight-loss.

Go to article

Identifying Discrepancies In Diagnosis Of Pcos With Use Of Different Diagnostic Criteria, Naveena Daram, Sangeeeta Kaur May 2022

Identifying Discrepancies In Diagnosis Of Pcos With Use Of Different Diagnostic Criteria, Naveena Daram, Sangeeeta Kaur

Posters

INTRODUCTION
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Two main diagnostic criteria are used for PCOS: the Rotterdam and Androgen Excess Society (AES) criteria. Depending on which criteria is used, the diagnosis of PCOS may change. Therefore, our study investigates the discrepancies in the diagnosis of PCOS when using the Rotterdam versus the AES scale in the Beaumont Health System. This is clinically significant because a PCOS diagnosis should not be made lightly as it can come with many lifelong social, emotional, and medical implications.

Go to article

Vbac Success In Women With Diabetes Mellitus Types I + Ii: A Pilot Study, Emma Randall, Rachel Taylor, Sarah Becker, Zeynep Alpay-Savasan May 2022

Vbac Success In Women With Diabetes Mellitus Types I + Ii: A Pilot Study, Emma Randall, Rachel Taylor, Sarah Becker, Zeynep Alpay-Savasan

Posters

Due to a rise in cesarean sections since the 1970s, the American College of Gynecology has acted to reduce unnecessary cesarean deliveries. In 2017, ACOG released clinical management guidelines for vaginal birth after cesarean delivery (VBAC), including a nomogram to predict VBAC success. This nomogram, developed by Grobman et al. (2007), explored factors impacting VBAC success for delivery at term for a singleton pregnancy. While the presence of diabetes was evaluated in the study, it was not found to be a significant factor in predicting outcome. This study will take a more detailed look at if pre-existing diabetes impacts a …

Go to article

The Impact Of Medical Scribes On Emergency Physician Diagnostic Testing And Diagnosis Charting, Lucas Nelson, Brett R. Todd May 2022

The Impact Of Medical Scribes On Emergency Physician Diagnostic Testing And Diagnosis Charting, Lucas Nelson, Brett R. Todd

Posters

INTRODUCTION
Since the widespread adoption of electronic medical records (EMRs), medical scribes have been increasingly utilized in emergency department (ED) settings to offload the documentation burden of emergency physicians (EPs). Scribes have been shown to increase EP productivity and satisfaction; however, little is known about their effects on the EP’s diagnostic process. We aimed to assess what effect, if any, scribes have on EP diagnostic test ordering and their documentation of differential diagnoses.

Go to article

Intraoperative Map, Vasopressors, And Opioids In Tf-Tavr Patients Undergoing Conscious Sedation Vs General Anesthesia, Brett J Friedman, Patrick Karabon, Wei C Lau May 2022

Intraoperative Map, Vasopressors, And Opioids In Tf-Tavr Patients Undergoing Conscious Sedation Vs General Anesthesia, Brett J Friedman, Patrick Karabon, Wei C Lau

Posters

INTRODUCTION
Aortic stenosis is a progressive narrowing of the aortic valve that can cause serious cardiovascular harm such as syncope, heart failure, and death if left untreated. Transfemoral-transcatheter aortic valve replacement (TF-TAVR) emerged in the last 10 years as an alternative for previously inoperable, high-risk patients. Studies suggest that monitored anesthesia for TF-TAVR using minimalist conscious sedation results in better outcomes (e.g., shorter length of stay, lower 30-day mortality) when compared to general anesthesia. However, there is a gap in knowledge of why conscious sedation is more successful. Recent studies have demonstrated the association of intraoperative mean arterial pressure (MAP) …

Go to article

Transcatheter Aortic Valve Replacement: Volume Impact On Length Of Stay And Readmissions, Alexander M. Balinksi, Patrick Karabon, Girish Pathangey, Amr E. Abbas May 2022

Transcatheter Aortic Valve Replacement: Volume Impact On Length Of Stay And Readmissions, Alexander M. Balinksi, Patrick Karabon, Girish Pathangey, Amr E. Abbas

Posters

INTRODUCTION
TAVR is an alternative to surgery in patients with severe aortic stenosis. Procedural volume impacts mortality but little is known of its effect on length of stay (LOS) and readmissions. We sought to examine the impact of transcatheter aortic valve replacement (TAVR) procedural volume on trends in LOS and hospital readmission rates from 2012 to 2016.

Go to article

Late Outcomes For Patients With Acute Chest Pain And Positive Fractional Flow Reserve By Computed Tomography, Zach Rollins, Jason Schott, Robert Safian May 2022

Late Outcomes For Patients With Acute Chest Pain And Positive Fractional Flow Reserve By Computed Tomography, Zach Rollins, Jason Schott, Robert Safian

Posters

INTRODUCTION
Testing with fractional flow reserve derived from computed tomography (FFRCT) can be used to stratify otherwise indeterminate grade stenoses on cardiac computed tomography angiography (CCTA). Long-term clinical outcomes using FFRCT have been reported in stable heart disease but not for acute chest pain (ACP). This study analyzes clinical outcomes in patients with ACP who underwent FFRCT, including the risk of mortality, myocardial infarction (MI), invasive coronary angiography (ICA), and revascularization.

Go to article

Does Aspirin Reduce Risk For Future Cardiovascular Events In Women With Diabetes?, Olivia Hillier, Amna Zeb, Pamela Marcovitz May 2022

Does Aspirin Reduce Risk For Future Cardiovascular Events In Women With Diabetes?, Olivia Hillier, Amna Zeb, Pamela Marcovitz

Posters

INTRODUCTION
The use of low dose aspirin (LDA) in primary prevention of cardiovascular events (CVE) is no longer recommended due to lack of benefit in prevention of primary outcome and increased bleeding risks. It’s postulated that LDA could still be of benefit in those with very high vascular risk including diabetes mellitus (DM) as it confers a higher risk for future CVE in women as compared to men. We conducted a meta-analysis to determine if use of low dose ASA is beneficial to lower CVE in women with multiple risk factors.

Go to article

Impact Of Polycystic Ovary Syndrome On Cardiovascular Disease In Obese Female Youth, Collin R. Walentine, Michael R. Brennan, Kristen J. Nadeau, Melanie Cree-Green May 2022

Impact Of Polycystic Ovary Syndrome On Cardiovascular Disease In Obese Female Youth, Collin R. Walentine, Michael R. Brennan, Kristen J. Nadeau, Melanie Cree-Green

Posters

INTRODUCTION
17% of youth in the United States are obese and the incidence is rising. Among obese adolescents, girls with polycystic ovary syndrome (PCOS) represent a vulnerable and understudied group. PCOS is strongly associated with dyslipidemia and cardiovascular disease (CVD) in adulthood, but studies of CVD in youth are limited. We hypothesized that obese youth with PCOS would show evidence of vascular dysfunction relative to girls with obesity without PCOS.

Go to article

Blunt Trauma And Diaphragm Injury In Children: An Analysis Of The National Trauma Data Bank, Sammie Lai, Patrick Karabon, Patrick Modren, Begum Akay, Anthony Stallion, Pavan Brahmamdam May 2022

Blunt Trauma And Diaphragm Injury In Children: An Analysis Of The National Trauma Data Bank, Sammie Lai, Patrick Karabon, Patrick Modren, Begum Akay, Anthony Stallion, Pavan Brahmamdam

Posters

INTRODUCTION
Trauma is the leading cause of mortality and morbidity in children. Traumatic diaphragm rupture (TDR) is a rare but serious injury that can be difficult to identify. The current literature includes individual case reports and single center case series only, which limits our ability to generalize those findings. The purpose of this study is to use the National Trauma Data Bank (NTDB) in order to examine the clinical outcomes of blunt TDR in the pediatric population.

Go to article

The Prognostic Significance Of Glucose-6-Phosphate Dehydrogenase As A Biomarker In Head And Neck Squamous Cell Carcinomas Treated With Conventional Chemoradiation, Kenneth H. Barker, Barbara L. Pruetz, Jessica D. Arden, Thomas J. Quinn, George D. Wilson May 2022

The Prognostic Significance Of Glucose-6-Phosphate Dehydrogenase As A Biomarker In Head And Neck Squamous Cell Carcinomas Treated With Conventional Chemoradiation, Kenneth H. Barker, Barbara L. Pruetz, Jessica D. Arden, Thomas J. Quinn, George D. Wilson

Posters

INTRODUCTION
The prognosis of patients with head and neck squamous cell carcinoma (HNSCC) treated with chemoradiation can be predicted using p16 as a surrogate biomarker of Human Papilloma Virus (HPV) status, but a subset of patients continues to do poorly despite a positive or negative p16 status. This project attempted to identify another biomarker, glucose-6-phosphate dehydrogenase (G6PD) as a marker for prognosis in HNSCC patients. Radiation induces oxidative damage to destroy tumor cells, and G6PD is a key enzyme involved in protecting cells from oxidative damage. The goal of this project was to identify a prognostic biomarker that would aid …

Go to article

Fluoroscopic Demonstration Of Thoracic Tumor Immobilization With High Frequency Percussive Ventilation, Cristian Solano, Ina M. Sala, Beverly Maurer, Ronald Levitin, Thomas M. Guerrero May 2022

Fluoroscopic Demonstration Of Thoracic Tumor Immobilization With High Frequency Percussive Ventilation, Cristian Solano, Ina M. Sala, Beverly Maurer, Ronald Levitin, Thomas M. Guerrero

Posters

INTRODUCTION
High frequency percussive ventilation (HFPV) is a novel immobilization technique that utilizes high frequency low tidal volume ventilation to produce endotracheal percussion. In a previous departmental study of chest wall motion immobilization, it was found that volunteers were able to tolerate HFPV for varying lengths of time – from a few to tens of minutes. By investigating a novel process to immobilize the chest wall, and thus thoracic tumors, it can allow for more localized radiation delivery and reduction of healthy tissue irradiation.

Go to article

Gauging The Impact Of Interactions With Autistic Children Early In Medical Education, Emily W. Yuen, Helen E. Huetterman, Jessica Korneder, Jason A. Wasserman, Mary O. Dereski May 2022

Gauging The Impact Of Interactions With Autistic Children Early In Medical Education, Emily W. Yuen, Helen E. Huetterman, Jessica Korneder, Jason A. Wasserman, Mary O. Dereski

Posters

INTRODUCTION
One in fifty-nine children in the United States are currently diagnosed with Autism Spectrum Disorder (ASD). Despite this high prevalence, medical students receive little training on this unique population. This project aims to determine the impact on first-year medical students’ attitudes toward treatment of children diagnosed with ASD following small group interactions in an Applied Behavior Analysis (ABA) clinic.

Go to article

Development Of Verbal Behavior In Early, Intensive Behavioral Therapy For Autism Spectrum Disorder, Mthya Jayakumar, Lesly Hendershot, Lori Warner, James F. Grogan May 2022

Development Of Verbal Behavior In Early, Intensive Behavioral Therapy For Autism Spectrum Disorder, Mthya Jayakumar, Lesly Hendershot, Lori Warner, James F. Grogan

Posters

INTRODUCTION
The current study will explore the relationships between motor imitation (MI) and verbal requesting skills in children who are diagnosed with autism spectrum disorder (ASD). With nearly half of children with ASD evidencing minimal verbal skills, supporting language development is crucial in interventions. Early, intensive behavioral intervention (EIBI) is recommended to help children achieve better developmental outcomes. Functional language training often begins with the verbal requesting skill, MAND. Research suggests that a series of rapid motor imitations before a vocal model could facilitate vocal speech, but little is known about how MI can longitudinally influence functional language development. This …

Go to article

Pediatric Obesity: A Survey Study Of Patients And Caregivers’ Concern And Interest In Specialized Programs, Dina Abdo, Ryan Rogers, Susan Edlibi, Aimee Pollak, Stacey Shubeck, Kerry P. Mychaliska May 2022

Pediatric Obesity: A Survey Study Of Patients And Caregivers’ Concern And Interest In Specialized Programs, Dina Abdo, Ryan Rogers, Susan Edlibi, Aimee Pollak, Stacey Shubeck, Kerry P. Mychaliska

Posters

INTRODUCTION
Body mass index (BMI) ≥ the 85th percentile for age and sex is considered overweight in the pediatric population. Pediatric obesity is defined as a BMI at or above the 95th percentile. According to the Centers for Disease Control (CDC), obesity prevalence has tripled over the past 50 years; 1 in 5 school-aged children has a diagnosis of obesity. The purpose of this study is to survey caregivers’ perceptions and concerns about their child’s weight and patient and caregiver interest in a comprehensive healthy lifestyle program.

Go to article

Effect Of Sars-Cov2 On Adolescent Phq-9 Screening Result, Anisah Hashmi, Aimee Pollak, Leah Ludwig, Kerry P. Mychaliska, Mara Rubenstein, Olufunke Adeyemo, Stacey Shubeck, Liu Qu, Mary Coffey May 2022

Effect Of Sars-Cov2 On Adolescent Phq-9 Screening Result, Anisah Hashmi, Aimee Pollak, Leah Ludwig, Kerry P. Mychaliska, Mara Rubenstein, Olufunke Adeyemo, Stacey Shubeck, Liu Qu, Mary Coffey

Posters

INTRODUCTION
The SARS-COV2 pandemic created numerous stressors for adolescents including financial insecurities, family illness or death, home schooling, discontinuation of group activities, and decreased peer interaction. Prior studies have shown an increased risk for self-reported depression symptoms in pediatric patients following traumatic events. The purpose of this study is to compare rates of newly diagnosed depression in adolescents and self-reported depression symptoms prior to and during the pandemic.

Go to article

Hearing Durability And Trajectory After Radiosurgery For Vestibular Schwannoma, Christian G. Fritz, Dennis I. Bojrab Ii, Nathan C. Tu, Christopher A. Schutt, Dennis I. Bojrab, Seilesh C. Babu May 2022

Hearing Durability And Trajectory After Radiosurgery For Vestibular Schwannoma, Christian G. Fritz, Dennis I. Bojrab Ii, Nathan C. Tu, Christopher A. Schutt, Dennis I. Bojrab, Seilesh C. Babu

Posters

INTRODUCTION
Vestibular schwannomas (VS) are benign skull base tumors arising from the eighth cranial nerve. Stereotactic radiosurgery (SRS) is emerging as treatment for smaller sized tumors with the intent being to prevent further tumor growth, thus avoiding mass-effect symptoms. Hearing outcomes are commonly presented as preservation of class A/B hearing (defined as Pure Tone Average (PTA) ≤50 dB with Word Recognition Score (WRS) ≥50 dB). Long-term follow-up data on hearing outcomes and hearing trajectory trends are limited.

Go to article

Let Them Play: A Prospective Study Of Postoperative Activity Restrictions In Children, Rachel Harvey, Begum Akay, Diane Studzinski, Nathan Novotny, Anthony Stallion, Pavan Brahmamdam May 2022

Let Them Play: A Prospective Study Of Postoperative Activity Restrictions In Children, Rachel Harvey, Begum Akay, Diane Studzinski, Nathan Novotny, Anthony Stallion, Pavan Brahmamdam

Posters

INTRODUCTION
We aim to compare time to resume full activity, postoperative outcomes, and describe family preferences of self-directed activity restrictions (SDAR) and physician-directed activity restrictions (PDAR) following routine pediatric surgeries.

Go to article

Irreversible Electroporation For Recurrent Pelvic Metastases: Case Series And Literature Review, Duncan A. Stevens, Jeffrey H. Savin, Brett J. Friedman, Michael A. Savin May 2022

Irreversible Electroporation For Recurrent Pelvic Metastases: Case Series And Literature Review, Duncan A. Stevens, Jeffrey H. Savin, Brett J. Friedman, Michael A. Savin

Posters

INTRODUCTION
Irreversible electroporation (IRE) is a nonthermal ablative technique that has potential safety advantages over thermal ablation in the treatment of tumors near critical structures. It creates an electrical field which forms permanent nanopores in the membranes of cells and triggers apoptosis. This case series reviews three patients with pelvic metastases from colorectal cancer treated with IRE.

Go to article

Characterization Of The Clinical Impact Of A Celiac Disease Algorithm On Diagnostic Workup Of Patients At Beaumont Hospital Royal Oak, Omid Vadpey, Gabriel N. Maine May 2022

Characterization Of The Clinical Impact Of A Celiac Disease Algorithm On Diagnostic Workup Of Patients At Beaumont Hospital Royal Oak, Omid Vadpey, Gabriel N. Maine

Posters

INTRODUCTION
Advancements in medical technology and laboratory testing have prompted room for more accurate diagnostic procedures that can aid in diagnostic efficiency, reducing time to diagnosis, unnecessary test ordering, and costs. Celiac Disease is a complex gastrointestinal autoimmune disorder characterized by symptoms that mimic other bowel diseases, such as diarrhea, steatorrhea, and malnutrition. The primary goal of this pilot study is to determine if the implementation of a diagnostic serologic algorithm differs from the current standard of practice for patients that are suspected of celiac disease at Beaumont Health-Royal Oak (BH-RO).

Go to article

Csf Flow Cytometry In Patients With Leukemia And Lymphoma, Patricia Rusli, James Huang May 2022

Csf Flow Cytometry In Patients With Leukemia And Lymphoma, Patricia Rusli, James Huang

Posters

INTRODUCTION
The use of flow cytometric testing in analyzing bodily fluid for hematologic neoplasms is not novel. Flow cytometric immunophenotyping of cerebrospinal fluid (CSF) has previously been demonstrated to have high sensitivity and specificity for the detection of lymphoma and leukemia. They are able to determine definitive diagnostic information from even very low cellularity samples. In this study, we reviewed the experience of our clinical flow cytometry laboratory in evaluating CSF specimens in order to find the disease distribution of positive CSF samples.

Go to article

Characterization Of Cd57+ T-Cell Subset In Blood, Bone Marrow, And Lymphoid Tissue, Michelle Ka Yan Wu, Xia Chen, James Huang May 2022

Characterization Of Cd57+ T-Cell Subset In Blood, Bone Marrow, And Lymphoid Tissue, Michelle Ka Yan Wu, Xia Chen, James Huang

Posters

INTRODUCTION
A CD57+ T-cell subset has shown to have diagnostic and prognostic significances in some cancers. However, its specific distributions in tissues and specific variations among different diseases are yet to be further defined. This Embark project aims to examine the distributions and antigen expression profiles in the CD57+ T-cell subset in peripheral blood (PB), bone marrow (BM), and lymph node (LN).

Go to article

Identification Of Aggressive Variants Of Mantle Cell Lymphoma Based On Flow Cytometry, Alan Nguyen, Alia Gupta, Marc Smith, James Huang May 2022

Identification Of Aggressive Variants Of Mantle Cell Lymphoma Based On Flow Cytometry, Alan Nguyen, Alia Gupta, Marc Smith, James Huang

Posters

INTRODUCTION
Mantle cell lymphoma (MCL) is a rare subtype of B-cell non-Hodgkin lymphoma characterized by a (1,14) translocation resulting in overexpression of cyclin D1.1 MCL variants and a heterogenous disease presentation make this a challenging diagnosis with a highly variable outcome. Pleomorphic and blastic variants have an aggressive clinical course and shorter survival than the classical type.2 The pleomorphic variant shows a marked variation in nuclear size, shape, and mitotic index.3 The blastic variant appears small and immature with fine chromatin mimicking acute leukemia.3 The aim of our study is to explore if flow cytometry analysis can help with the …

Go to article

First Prev Next Last