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- Manuscripts, Articles, Book Chapters and Other Papers (1314)
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Articles 1891 - 1920 of 2695
Full-Text Articles in Medical Specialties
Altered Detrusor Contractility And Voiding Patterns In Mice Lacking The Mechanosensitive Trek-1 Channel., Ricardo H. Pineda, Joseph Hypolite, Sanghee Lee, Alonso Carrasco, Nao Iguchi, Randall B. Meacham, Anna P. Malykhina
Altered Detrusor Contractility And Voiding Patterns In Mice Lacking The Mechanosensitive Trek-1 Channel., Ricardo H. Pineda, Joseph Hypolite, Sanghee Lee, Alonso Carrasco, Nao Iguchi, Randall B. Meacham, Anna P. Malykhina
Manuscripts, Articles, Book Chapters and Other Papers
BACKGROUND: Previously published results from our laboratory identified a mechano-gated two-pore domain potassium channel, TREK-1, as a main mechanosensor in the smooth muscle of the human urinary bladder. One of the limitations of in vitro experiments on isolated human detrusor included inability to evaluate in vivo effects of TREK-1 on voiding function, as the channel is also expressed in the nervous system, and may modulate micturition via neural pathways. Therefore, in the present study, we aimed to assess the role of TREK-1 channel in bladder function and voiding patterns in vivo by using TREK-1 knockout (KO) mice.
METHODS: Adult C57BL/6 …
Abcb1 Snp Predicts Outcome In Patients With Acute Myeloid Leukemia Treated With Gemtuzumab Ozogamicin: A Report From Children's Oncology Group Aaml0531 Trial., Roya Rafiee, Lata Chauhan, Todd A. Alonzo, Yi-Cheng Wang, Ahlam Elmasry, Michael R. Loken, Jessica Pollard, Richard Aplenc, Susana Raimondi, Betsy A. Hirsch, Irwin D. Bernstein, A S. Gamis, Soheil Meshinchi, Jatinder K. Lamba
Abcb1 Snp Predicts Outcome In Patients With Acute Myeloid Leukemia Treated With Gemtuzumab Ozogamicin: A Report From Children's Oncology Group Aaml0531 Trial., Roya Rafiee, Lata Chauhan, Todd A. Alonzo, Yi-Cheng Wang, Ahlam Elmasry, Michael R. Loken, Jessica Pollard, Richard Aplenc, Susana Raimondi, Betsy A. Hirsch, Irwin D. Bernstein, A S. Gamis, Soheil Meshinchi, Jatinder K. Lamba
Manuscripts, Articles, Book Chapters and Other Papers
Gemtuzumab-ozogamicin (GO), a humanized-anti-CD33 antibody linked with the toxin-calicheamicin-γ is a reemerging and promising drug for AML. Calicheamicin a key element of GO, induces DNA-damage and cell-death once the linked CD33-antibody facilitates its uptake. Calicheamicin efflux by the drug-transporter PgP-1 have been implicated in GO response thus in this study, we evaluated impact of ABCB1-SNPs on GO response. Genomic-DNA samples from 942 patients randomized to receive standard therapy with or without addition of GO (COG-AAML0531) were genotyped for ABCB1-SNPs. Our most interesting results show that for rs1045642, patients with minor-T-allele (CT/TT) had better outcome as compared to patients with CC …
The Role Of Outdoor Tree Pollen Levels On Healthcare Visits For Respiratory Infections In Infants And Toddlers: A Case Cross-Over Analysis, Adam J. Van Mason
The Role Of Outdoor Tree Pollen Levels On Healthcare Visits For Respiratory Infections In Infants And Toddlers: A Case Cross-Over Analysis, Adam J. Van Mason
Research Days
No abstract provided.
A Retrospective Review Of Project Instruct: Improving Sexual And Reproductive Health Amongst At-Risk Teens, April Mcneill Md
A Retrospective Review Of Project Instruct: Improving Sexual And Reproductive Health Amongst At-Risk Teens, April Mcneill Md
Research Days
No abstract provided.
Family Entropy: Understanding The Organization Of The Home Environment And Impact On Health Behaviors And Weight In School-Age Children, Carolyn Bates
Family Entropy: Understanding The Organization Of The Home Environment And Impact On Health Behaviors And Weight In School-Age Children, Carolyn Bates
Research Days
No abstract provided.
Impact Of A Mobile Device-Based Clinical Decision Support Tool On Guideline Adherence And Mental Workload Among Trainees And Attending Physicians, Katherine M. Richardson
Impact Of A Mobile Device-Based Clinical Decision Support Tool On Guideline Adherence And Mental Workload Among Trainees And Attending Physicians, Katherine M. Richardson
Research Days
No abstract provided.
Measuring Clinical Weight Loss In Young Children With Severe Obesity: Comparison Of Outcomes Using Zbmi, Modified Zbmi, And Percent Of 95th Percentile, Carolyn Bates
Research Days
No abstract provided.
Heavy Menstrual Bleeding In Adolescent Females With Platelet Function Disorders, Lauren Amos Md
Heavy Menstrual Bleeding In Adolescent Females With Platelet Function Disorders, Lauren Amos Md
Research Days
No abstract provided.
Pediatric Ppi Use And Fractures, Nathan R. Fleishman Md, Thomas M. Attard, Troy E. Richardson
Pediatric Ppi Use And Fractures, Nathan R. Fleishman Md, Thomas M. Attard, Troy E. Richardson
Research Days
No abstract provided.
Clinical Utility Of Exon Deletion/Duplication Microarray Testing - A Children’S Mercy Kansas City Two-Year Experience, Binu Porath
Clinical Utility Of Exon Deletion/Duplication Microarray Testing - A Children’S Mercy Kansas City Two-Year Experience, Binu Porath
Research Days
No abstract provided.
Provider Education And Rapid Antigen Detection Test Use In An Academic Pediatric Clinic, Steven Dahl
Provider Education And Rapid Antigen Detection Test Use In An Academic Pediatric Clinic, Steven Dahl
Research Days
No abstract provided.
Attitudes Of Emergency Medical Service (Ems) Providers Towards Pediatric Death And Outside-Of-Hospital Do Not Resuscitate (Dnr) Orders, Clay Yaklin
Research Days
No abstract provided.
Adhd Clinic Outcomes: Assessing Dose Response Over Time, Caroline Pittard
Adhd Clinic Outcomes: Assessing Dose Response Over Time, Caroline Pittard
Research Days
No abstract provided.
Prevalence Of Sexual Minorities Among Adolescents Evaluated For Polycystic Ovary Syndrome, Cintya Schweisberger
Prevalence Of Sexual Minorities Among Adolescents Evaluated For Polycystic Ovary Syndrome, Cintya Schweisberger
Research Days
No abstract provided.
Changes In Pt, Aptt And Platelet Counts After Ich Resulting From Accidental Trauma, Sara Kilbride
Changes In Pt, Aptt And Platelet Counts After Ich Resulting From Accidental Trauma, Sara Kilbride
Research Days
No abstract provided.
Racial/Ethnic Demographics Of Participants In Clinical Trials Of Biologics Used For Asthma, Susamita Kesh
Racial/Ethnic Demographics Of Participants In Clinical Trials Of Biologics Used For Asthma, Susamita Kesh
Research Days
No abstract provided.
Parental Observation Of Environmental Exposures In The Home Of Children With Asthma, Hannah N. Neuhaus
Parental Observation Of Environmental Exposures In The Home Of Children With Asthma, Hannah N. Neuhaus
Research Days
No abstract provided.
Initial Evaluation Of Adolescent Females Hospitalized With Heavy Menstrual Bleeding, Lauren Amos Md
Initial Evaluation Of Adolescent Females Hospitalized With Heavy Menstrual Bleeding, Lauren Amos Md
Research Days
No abstract provided.
Guided Mentorship: Enhancing Pediatric Resident’S Skills In Cardiopulmonary Resuscitation, Alyssa Stoner
Guided Mentorship: Enhancing Pediatric Resident’S Skills In Cardiopulmonary Resuscitation, Alyssa Stoner
Research Days
No abstract provided.
Characterization Of Low Resource Utilization Observation Status Hospitalizations Within Children's Hospitals, David C. Synhorst
Characterization Of Low Resource Utilization Observation Status Hospitalizations Within Children's Hospitals, David C. Synhorst
Research Days
No abstract provided.
Impact Of A Mobile Device-Based Clinical Decision Support Tool On Guideline Adherence And Mental Workload Among Trainee And Attending Physicians, Katherine M. Richardson
Impact Of A Mobile Device-Based Clinical Decision Support Tool On Guideline Adherence And Mental Workload Among Trainee And Attending Physicians, Katherine M. Richardson
Presentations
This study evaluated PedsGuide, an app used to evaluate serious bacterial infections in febrile infants.
The Effect Of Antihypertensive Medications Dosing On Blood Pressure Control And Left Ventricular Hypertrophy In Children With Chronic Kidney Disease, Benjamin A. Matta
The Effect Of Antihypertensive Medications Dosing On Blood Pressure Control And Left Ventricular Hypertrophy In Children With Chronic Kidney Disease, Benjamin A. Matta
Research Days
No abstract provided.
Relationship Between Hemolytic Index Early In Life And Development Of Abnormal Transcranial Doppler Velocities In Pediatric Patients With Sickle Cell Anemia, Derrick L. Goubeaux
Relationship Between Hemolytic Index Early In Life And Development Of Abnormal Transcranial Doppler Velocities In Pediatric Patients With Sickle Cell Anemia, Derrick L. Goubeaux
Research Days
No abstract provided.
Methotrexate Polyglutamates And The Potential Role In Pediatric Inflammatory Bowel Disease, Ryan Morrow
Methotrexate Polyglutamates And The Potential Role In Pediatric Inflammatory Bowel Disease, Ryan Morrow
Research Days
No abstract provided.
Maximal Oxygen Consumption Recovery Delay In A Fontan Population, Karoline Krzywda
Maximal Oxygen Consumption Recovery Delay In A Fontan Population, Karoline Krzywda
Research Days
No abstract provided.
Effect Of Crohn’S Disease On Villous Length And Cyp3a4 Expression In The Pediatric Small Intestine, Brian D. Chapron
Effect Of Crohn’S Disease On Villous Length And Cyp3a4 Expression In The Pediatric Small Intestine, Brian D. Chapron
Research Days
No abstract provided.
Does Palliative Care Involvement Influence Location Of Death?, Joy L. Solano
Does Palliative Care Involvement Influence Location Of Death?, Joy L. Solano
Research Days
No abstract provided.
Predictive Performance Of Existing Population Pharmacokinetic Models Of Tacrolimus In Pediatric Kidney Transplant Recipients, Alenka Chapron
Predictive Performance Of Existing Population Pharmacokinetic Models Of Tacrolimus In Pediatric Kidney Transplant Recipients, Alenka Chapron
Research Days
No abstract provided.
Thyrotoxicosis Presenting With Nondiabetic Ketoacidosis In A 4 Year Old Female, Henry S. Jeng Dr
Thyrotoxicosis Presenting With Nondiabetic Ketoacidosis In A 4 Year Old Female, Henry S. Jeng Dr
Research Days
No abstract provided.
Lymphocytic Lobulitis Presenting In An Adolescent Female: A Case Report, Kevin Meilak Md
Lymphocytic Lobulitis Presenting In An Adolescent Female: A Case Report, Kevin Meilak Md
Research Days
No abstract provided.