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Articles 1531 - 1560 of 2695
Full-Text Articles in Medical Specialties
Where Are They Now? Spanish Utilization And Career Direction Of Graduates Of A Pediatric Bilingual Continuity Clinic, Jodi Dickmeyer, Katie Mcanany, Sarah Stone, John Cowden
Where Are They Now? Spanish Utilization And Career Direction Of Graduates Of A Pediatric Bilingual Continuity Clinic, Jodi Dickmeyer, Katie Mcanany, Sarah Stone, John Cowden
Posters
Background: The Clínica Hispana de Cuidados de Salud (CHiCoS) Program was created in 2009 to prepare bilingual (English-Spanish) pediatric residents to independently give safe, effective care to Spanish-speaking families. By providing 1:1 support from a culture and language coach over three years of residency, CHiCoS has improved residents’ cultural and linguistic skills and families' perceptions of care. The effects of such training on residents’ future careers have not been formally studied.
Objective: To describe the careers of former CHiCoS residents, the impact of culture and language training on their practice, and opportunities for post-CHiCoS cultural and language training.
Design/Methods: In …
Differences In Ed And Inpatient Utilization By Location Of Primary Care: Co-Location At A Head Start Center Vs. Academic Primary Care Clinic Setting, Rupal Gupta, Jeffrey D. Colvin
Differences In Ed And Inpatient Utilization By Location Of Primary Care: Co-Location At A Head Start Center Vs. Academic Primary Care Clinic Setting, Rupal Gupta, Jeffrey D. Colvin
Posters
Background: Children (ED) and inpatient utilization. Co-location of a primary care clinic within a Head Start center (HSC) includes nursing surveillance of classrooms and same-day primary care access, which allows students at the HSC to be seen immediately for acute care during the day. Consequently, co-location of primary care within a HSC may reduce barriers to acute care for those students, thereby lowering their ED and inpatient utilization.
Objective: To compare ED and inpatient utilization of students from a HSC with co-located primary care to patients treated at an academic primary care clinic (APCC).
Design/Methods: In this retrospective cross-sectional study, …
Learning From The Past: A Novel And Sustainable Initiative To Reducing Unplanned Extubations In A Level Iv Neonatal Intensive Care Unit, Yonatan Kurland, Dena Hubbard, Eugenia K. Pallotto
Learning From The Past: A Novel And Sustainable Initiative To Reducing Unplanned Extubations In A Level Iv Neonatal Intensive Care Unit, Yonatan Kurland, Dena Hubbard, Eugenia K. Pallotto
Posters
Background: Unplanned extubations (UPEs) are a cause of significant morbidity and mortality in neonates. Multiple successful interventions had been previously implemented in our NICU including standardized endotracheal tube (ETT) securement procedures, bedside checklists, and multi-disciplinary debriefing. In our unit greater than 65% of UPEs occur in neonates under 1.5kg who are particularly sensitive to small adjustments in tube position. We designed a novel approach to reducing UPEs in this patient population.
Objective:
Design/Methods: We hypothesized that increased awareness of historical ETT position would both prevent unnecessary ETT position adjustments and encourage prophylactic adjustments to adjust for significant weight gain or …
Neonatal Dna Methylation As A Predictor Of Cognitive, Language, And Motor Performance At 24 Months Adjusted Age, Among Children Born Very Preterm, Stefan Graw, Marie Camerota, Brian S. Carter, Jennifer Helderman, Julie A. Hofheimer, Elizabeth C. Mcgowan, Charles R. Neal, Steven Pastyrnak, Lynne Smith, Michael O'Shea, Barry Lester, Carment Marsit, Todd M. Everson
Neonatal Dna Methylation As A Predictor Of Cognitive, Language, And Motor Performance At 24 Months Adjusted Age, Among Children Born Very Preterm, Stefan Graw, Marie Camerota, Brian S. Carter, Jennifer Helderman, Julie A. Hofheimer, Elizabeth C. Mcgowan, Charles R. Neal, Steven Pastyrnak, Lynne Smith, Michael O'Shea, Barry Lester, Carment Marsit, Todd M. Everson
Presentations
Background: Infants born prematurely are at increased risk for neurodevelopmental impairments during childhood and early neurodevelopment can be influenced by multiple factors (perinatal and environmental exposures, genetics). DNA methylation (DNAm) can also be influenced by these factors and be reflective of health and development, and thus may provide an integrated measure of early life risk for neurodevelopmental outcomes.
Objective: To test whether neonatal DNAm is predictive of cognitive, language, and/or motor performance at 24 months of age in children that were born very preterm.
Design/Methods: We studied 433 neonates born < 30 weeks postmenstrual age in the Neonatal Neurobehavioral Outcomes in Very Preterm Infants (NOVI) study. Neonatal DNAm was measured from buccal swabs at NICU discharge via the Illumina MethylationEPIC BeadArray. Cognitive, motor, and language performance were assessed by the Bayley Scales of Infant and Toddler Development-III (BSID-III) at 24 months adjusted age, with mild and moderate impairment defined as composite scores < 85 and < 70. We used an elastic net regression and leave-one-out cross-validation to limit overfitting and selection bias, to identify sets of DNAm sites that were predictive of composite Bayley scores. For the leave-one-out cross-validation, a model was trained on all but one sample to make a prediction on that held-out sample. This step is repeated until each sample was held out and predicted once. In addition, for a given hold-out sample, all siblings were removed from its training set. The performance of predicted composite scores were evaluated by their correlation with the measured Bayley scores and the area under the receiver operating characteristic (ROC) curve (AUC) based on dichotomized Bayley scores (< 85 and < 70).
Results: We identified sets of DNAm sites (including 33-306 sites) …
Improving The Rate Of Emergency Department Physician Pre-Procedure Time-Out Documentation For Deep Sedation And Cutaneous Abscess Incision And Drainage, Arjun Sarin, Nikita Sharma, Shobhit Jain
Improving The Rate Of Emergency Department Physician Pre-Procedure Time-Out Documentation For Deep Sedation And Cutaneous Abscess Incision And Drainage, Arjun Sarin, Nikita Sharma, Shobhit Jain
Posters
Background: The pre-procedure time-out, an important safety measure to verify patient identity and accuracy of a planned procedure, and Joint Commission requirement, is not documented consistently by physicians in our emergency department (ED). Deep sedation and cutaneous abscess incision and drainage (I&D) are two high-risk procedures performed in the ED, supporting the use of a time-out in this setting. Between June 2018 and May 2019, a pre-procedure time-out was documented in the physician procedure note of the electronic medical record (EMR) for 75% of deep sedations, and 94% of I&Ds.
Objective: We aimed to improve ED physician pre-procedure time-out documentation …
Improving Access To Spanish Covid-19 Resources At A Children’S Hospital, Fernando Zapata, Romina Barral, July K. Jean Cuevas, Lines Vargas Collado, Nicholas Clark, Amanda Montalbano, Cristina Fernandez
Improving Access To Spanish Covid-19 Resources At A Children’S Hospital, Fernando Zapata, Romina Barral, July K. Jean Cuevas, Lines Vargas Collado, Nicholas Clark, Amanda Montalbano, Cristina Fernandez
Posters
Background: The COVID-19 pandemic disproportionately impacts Spanish-speaking communities. COVID-19-related health information is overall more available in English than Spanish. From May to August 2020, Spanish COVID-19-related resources on our institution’s website had an average of 2954 views/month compared to 48573 views/month to the English COVID-19-related resources.
Objective:
Our project aim was to increase the percent of page views for Spanish COVID-19-related resources on our institution’s website from 5.7% of the total views to the COVID-19-related pages, to 20% from September 2020 through June 2021.
Design/Methods: An ethnically diverse, multidisciplinary team including physicians proficient in Spanish as well as our institution’s …
Registration Of Newly Diagnosed Children With Autism Spectrum Disorder And Developmental Disabilities At State Regional Offices, Whitney Rolling, Rachel Goodson
Registration Of Newly Diagnosed Children With Autism Spectrum Disorder And Developmental Disabilities At State Regional Offices, Whitney Rolling, Rachel Goodson
Posters
• In fiscal year 2020, 39,220 Missouri residents utilized developmental disability services through the Missouri Department of Mental Health.1 • Developmental disability services account for 53% of Missouri’s state mental health funding (about 1.3 billion dollars annually).
• Physicians and psychologists are required for making eligible diagnoses, but registration for state support is patient dependent and can be perceived as an extensive paperwork process.
• Project Goal: Measure and increase the percentage of eligible patients registered for their state mental health resource offices.
Efficacy And Safety Of Bardoxolone Methyl In Pediatric Patients With Alport Syndrome In Cardinal Phase 3 Trial, Bradley A. Warady, Sharon Andreol, Vimal Chadha, Melanie Chin, Rasheed Gbadegesin, Keisha Gibson, Debbie Gipson, Angie Goldsberry, Kenneth Lieberman, Colin Meyer, Kevin Meyers, Nozu Kandai, Megan O'Grady, Michelle Rheault, Clifford Kashtan
Efficacy And Safety Of Bardoxolone Methyl In Pediatric Patients With Alport Syndrome In Cardinal Phase 3 Trial, Bradley A. Warady, Sharon Andreol, Vimal Chadha, Melanie Chin, Rasheed Gbadegesin, Keisha Gibson, Debbie Gipson, Angie Goldsberry, Kenneth Lieberman, Colin Meyer, Kevin Meyers, Nozu Kandai, Megan O'Grady, Michelle Rheault, Clifford Kashtan
Posters
Background: Alport syndrome accounts for an estimated 3% of children with end-stage kidney disease in the US (USRDS, 2014). Whereas current management recommendations include the use of renin-angiotensin-aldosterone system inhibitors (RAASi) in patients with proteinuria, no specific therapies have been approved for this disease.
Objective: A Phase 3 study (CARDINAL; NCT03019185) evaluated the safety and efficacy of bardoxolone methyl (Bard) in adult and adolescent patients with Alport syndrome.
Design/Methods: CARDINAL was an international, multicenter, double-blind, placebo-controlled, randomized trial conducted over two years in patients with confirmed diagnosis of Alport syndrome. Patients aged 12 to 70 years old with baseline eGFR …
Perinatal Exposure To Interleukin-6 (Il-6): A Model To Study Influence Of Developmental Insult On Susceptibility To Chronic Kidney Disease (Ckd), Tarak Srivastava, Robert E. Garola, Varun Chandra Boinpelly, Jianping Zhou, Daniel P. Heruth, Mohammad Rezaiekhaligh, M. Farhan Ali, Lakshmi Priya, Uri Alon, Trupti Joshi, Yuexu Jiang, Ellen T. Mccarthy, Ram Sharma, Madhulika Sharma, Gregory Vanden Heuvel, Virginia J. Savin, Pramod B. Mahajan, Mukut Sharma
Perinatal Exposure To Interleukin-6 (Il-6): A Model To Study Influence Of Developmental Insult On Susceptibility To Chronic Kidney Disease (Ckd), Tarak Srivastava, Robert E. Garola, Varun Chandra Boinpelly, Jianping Zhou, Daniel P. Heruth, Mohammad Rezaiekhaligh, M. Farhan Ali, Lakshmi Priya, Uri Alon, Trupti Joshi, Yuexu Jiang, Ellen T. Mccarthy, Ram Sharma, Madhulika Sharma, Gregory Vanden Heuvel, Virginia J. Savin, Pramod B. Mahajan, Mukut Sharma
Posters
Background: CKD and obesity are marked by elevated pro-inflammatory cytokines, including IL-6. Pregnant obese women are associated with 1.5- to 2-fold increase in serum IL-6, newborns with smaller kidney/body weight ratio, kidney anomalies and increased susceptibility to CKD. Maternal IL-6, but not TNFα or IL-1β, can cross the placental barrier and enter fetal compartment.
Objective: We examined the role of (a) maternal injection of IL-6 during mid-gestation, similar to levels observed in pregnant obese women, on kidney development as a specific molecular surrogate of gestational inflammation and (b) IL-6 on glomerular filtration barrier.
Design/Methods: Pregnant mice received IL-6 (10 pg/g …
Teaching Pediatric Procedural Pain And Anxiety Management To Residents: Early Outcomes Of A Newly Developed Curriculum, Jennifer J. Dilts, Brian R. Lee, Shobhit Jain, Ross Newman, Sarah Fouquet, Michael Brancato, Kadriye O. Lewis
Teaching Pediatric Procedural Pain And Anxiety Management To Residents: Early Outcomes Of A Newly Developed Curriculum, Jennifer J. Dilts, Brian R. Lee, Shobhit Jain, Ross Newman, Sarah Fouquet, Michael Brancato, Kadriye O. Lewis
Posters
Background: Poorly managed pediatric pain has negative long-term outcomes, including needle phobia, increased pain and anxiety with subsequent procedures, and healthcare avoidance in adulthood. Evidence-based interventions to reduce procedural pain and anxiety are vastly underutilized, and a literature search revealed no specific curriculum to teach residents optimal skills for pain and anxiety management in minor procedures (e.g. venipuncture, laceration repair). Thus, we developed a multimedia-based lecture with PowerPoint, utilizing results from a focus group interview (conducted with 7 pediatric residents, to determine educational content and identify residents’ needs and learning preferences).
Objective: To measure residents’ learning outcomes (knowledge, attitudes, perceived …
Virtual Child Neurology Education During Covid-19 And Beyond, Jennifer J. Dilts, Rose N. Gelineau-Morel
Virtual Child Neurology Education During Covid-19 And Beyond, Jennifer J. Dilts, Rose N. Gelineau-Morel
Posters
Background: Even prior to the Coronavirus Disease 2019 (COVID-19) pandemic, Children’s Mercy Kansas City’s large neurology division struggled to engage learners in educational conferences. With 113 division members across 5 locations, attending conferences was challenging. While some conferences were live-streamed, we offered no recorded lectures, and most conferences were attended solely by trainees and 3-4 select faculty. COVID-19 eliminated in-person group learning opportunities.
Objective: We aimed to rapidly develop and implement a comprehensive and inclusive virtual child neurology curriculum and assess its impact.
Design/Methods: We created a neurology education “team” using Microsoft® Teams. Within 1 week of beginning social distancing, …
Human Lactoferrin And The Siderophore Aerobactin Independently Impact Intestinal Invasion By Neonatal Escherichia Coli Bacteremia Isolates, Susana Chavez-Bueno, Joshua Wheatley, Jennifer Tabakh
Human Lactoferrin And The Siderophore Aerobactin Independently Impact Intestinal Invasion By Neonatal Escherichia Coli Bacteremia Isolates, Susana Chavez-Bueno, Joshua Wheatley, Jennifer Tabakh
Posters
Background: E. coli is a major cause of neonatal sepsis. After ingestion, E. coli translocates the neonatal gut causing bacteremia. E. coli virulence depends on iron acquisition mechanisms, including siderophore systems. Lactoferrin (LF) protects against neonatal sepsis through immunomodulatory and antimicrobial effects which include iron chelation. However, it is not known whether siderophores in neonatal E. coli strains have an impact on LF’s effects on bacterial invasion and survival in intestinal epithelium.
Objective: To investigate the effects of human LF and the siderophore aerobactin on intestinal invasion and survival of septicemia-producing neonatal E. coli.
Design/Methods: Neonatal E. coli septicemia isolates …
Gender Dysphoria, General Well-Being, Bmi, And Weight-Related Behaviors Among Adolescent Transgender Males, Timothy A. Roberts, Anna Egan, Mirae J. Fornander, Christine Moser, Michaela Voss
Gender Dysphoria, General Well-Being, Bmi, And Weight-Related Behaviors Among Adolescent Transgender Males, Timothy A. Roberts, Anna Egan, Mirae J. Fornander, Christine Moser, Michaela Voss
Posters
Background: Gender dysphoria is associated body-dissatisfaction, abnormal weight and weight-related behaviors.
Objective: Describe the association of gender dysphoria severity and general well-being with Body Mass Index (BMI) and weight related behaviors among transgender males.
Design/Methods: Retrospective review of 118 transgender male patients presenting to initiate gender-affirming medical care in 2017-2020. Gender dysphoria confirmed by an experienced mental health provider. We measured parent and patient reports of patient general well-being [Pediatric Quality of Life Inventory (PedsQL) 4.0 General Well-Being Scale], severity of gender dysphoria [Transgender Congruence Scale (TCS) [n=47 for TCS] and Gender Identity/Gender Dysphoria Questionnaire (GIDYQ-AA)], weight related intentions, and …
Developing A Breastfeeding Advocacy Agenda Through Insight From Breastfeeding Experiences Of Faculty Physicians, Pooja French, Elizabeth Simpson, Courtney Winterer, Jodi Dickmeyer, Sarah Stone
Developing A Breastfeeding Advocacy Agenda Through Insight From Breastfeeding Experiences Of Faculty Physicians, Pooja French, Elizabeth Simpson, Courtney Winterer, Jodi Dickmeyer, Sarah Stone
Posters
Background: Despite forward progress in recent decades surrounding lactation support, physician mothers continue to face challenges in achieving their breastfeeding goals.
Objective: We aimed to survey personal breastfeeding experiences of faculty physician mothers who recently breastfed to help formulate a robust breastfeeding advocacy agenda. We hypothesized finding high incidence modifiable factors related to lactation support could improve physician breastfeeding goal success and ultimately improve the overall breastfeeding experience.
Design/Methods: An anonymous breastfeeding survey containing both quantitative and qualitative items was sent to female faculty physicians at an academic children’s hospital in 2020. Inclusion criteria included female faculty physicians who had …
Recurrent Neonatal Herpes Simplex Virus Infection Associated With Irf7 And Unc93b1 Variants, Venkatesh Sampath, Megan H. Tucker, Heather Menden, Sheng Xia, Wei Yu, Nikita Raje
Recurrent Neonatal Herpes Simplex Virus Infection Associated With Irf7 And Unc93b1 Variants, Venkatesh Sampath, Megan H. Tucker, Heather Menden, Sheng Xia, Wei Yu, Nikita Raje
Posters
Background: Neonatal herpes simplex virus (HSV) is a devastating disease with high mortality. In adults and children, genetic variants in the toll-like receptor 3 (TLR3) pathway increase susceptibility to herpes simplex encephalitis (HSE), but the genetic basis of susceptibility to neonatal HSV is unknown. We hypothesized that deleterious variants in the TLR3 pathway increased vulnerability to HSE in neonates. We investigated immunogenetic studies in an infant with neonatal skin, eye, mouth (SEM) HSV followed by HSE.
Objective: To combine exome sequencing with in vivo and in vitro immune functional analysis to discover the immunogenetic basis of HSV vulnerability in proband. …
Medicaid Expenditures Among Children With Documented Obesity, Kathyrn Kyler, Matt Hall, Jessica L. Bettenhausen, Sarah Hampl, Ann M. Davis
Medicaid Expenditures Among Children With Documented Obesity, Kathyrn Kyler, Matt Hall, Jessica L. Bettenhausen, Sarah Hampl, Ann M. Davis
Presentations
Background: Obesity rates continue to rise among children, but knowledge regarding spending patterns of Medicaid enrollees with documented obesity are lacking.
Objective: We aimed to describe Medicaid expenditure patterns and determine the degree to which specific clinical characteristics and conditions contribute to high expenditures among children with obesity.
Design/Methods: We performed a retrospective cross-sectional analysis of children aged 2-17 years with a diagnosis code (ICD-10) for obesity continuously enrolled in the nationally-representative 2017 Medicaid Marketscan database. Expenditures were measured as median per member per year (PMPY) spending and categorized based on prior literature from low to high PMPY expenditure groups: …
Prevalence Of Mycoplasma Genitalium And Macrolide Resistance In Adolescent Females Receiving Care At A Pediatric Hospital, Kayla Barnes, Bishnu Adhikari, Rangaraj Selvarangan, Christopher J. Harrison, Melissa K. Miller
Prevalence Of Mycoplasma Genitalium And Macrolide Resistance In Adolescent Females Receiving Care At A Pediatric Hospital, Kayla Barnes, Bishnu Adhikari, Rangaraj Selvarangan, Christopher J. Harrison, Melissa K. Miller
Posters
Background: Mycoplasma genitalium is an established sexually transmitted cause of nongonococcal urethritis in males and macrolide resistance is increasing. The pathogenic role is less well-defined in adolescent females and guidelines recommend M. genitalium testing only be considered in cases of persistent or recurrent cervicitis and pelvic inflammatory disease (PID). We lack understanding of the prevalence and macrolide resistance of M. genitalium in adolescent females.
Objective: To determine the prevalence of M. genitalium and rate of detected macrolide resistance among adolescent females seeking care at a pediatric children’s hospital.
Design/Methods: We collected 200 salvaged urogenital samples (56 urine and 144 vaginal) …
Multimodal Pain Control In Common Neonatal Surgeries: Post-Operative Pain Protocol Reduces Opiate Exposure And Side Effects, Jamesia Donato, Nefertari Terrill-Jones, Ashley K. Sherman, Warren Teachout, Stephanie Prince, Alexandra Oschman, Daphne Reavey, Darian Younger, Tamorah R. Lewis
Multimodal Pain Control In Common Neonatal Surgeries: Post-Operative Pain Protocol Reduces Opiate Exposure And Side Effects, Jamesia Donato, Nefertari Terrill-Jones, Ashley K. Sherman, Warren Teachout, Stephanie Prince, Alexandra Oschman, Daphne Reavey, Darian Younger, Tamorah R. Lewis
Posters
Background: Opioids are the primary post-operative (post-op) analgesic in neonates. Side effects include hypotension, apnea and ileus. Previous studies show IV acetaminophen decreases opiate need in specific populations including cleft palate repair, cardiac surgery. The effect of IV acetaminophen as part of a post-op pain algorithm is not known in common neonatal surgical procedures.
Objective: To determine if (a) a post-op pain algorithm including IV acetaminophen and (b) IV acetaminophen exposure reduces cumulative opioid requirements in neonates undergoing common surgeries in the NICU.
Design/Methods: This is a retrospective cohort study comparing cumulative post-operative opiate exposure between infants with common surgeries …
Rates Of Positive Suicide Screens Among The Emergency, Inpatient And Outpatient Clinics At A Tertiary Care Children’S Hospital, Fajar Raza, Hung-Wen Yeh, John Lantos, Mark Connelly, Shayla Sullivant
Rates Of Positive Suicide Screens Among The Emergency, Inpatient And Outpatient Clinics At A Tertiary Care Children’S Hospital, Fajar Raza, Hung-Wen Yeh, John Lantos, Mark Connelly, Shayla Sullivant
Posters
Background: Prior research has suggested that rates and acuity of suicidality are elevated among patients seen in EDs and in certain clinics. However, the occurrence and severity of suicide risk has been rarely studied in the pediatric clinic populations due in part to unsystematic screening. We examined suicidality across different pediatric clinical care settings based on data from our newly implemented hospital-wide suicide risk screening program.
Objective: To determine a) which patient populations presented with the highest rates of suicidality; and b) the percentage of patients who had current thoughts of suicide and were thus deemed “acute.”
Design/Methods: We conducted …
Factors Associated With Reduced Infliximab Exposure In The Treatment Of Pediatric Autoimmune Disorders: A Cross-Sectional Prospective Convenience Sampling Study., Ryan S. Funk, Valentina Shakhnovich, Yu Kyoung Cho, Kishore Polireddy, Taina Hudson, Kyle Gress, Mara L. Becker
Factors Associated With Reduced Infliximab Exposure In The Treatment Of Pediatric Autoimmune Disorders: A Cross-Sectional Prospective Convenience Sampling Study., Ryan S. Funk, Valentina Shakhnovich, Yu Kyoung Cho, Kishore Polireddy, Taina Hudson, Kyle Gress, Mara L. Becker
Manuscripts, Articles, Book Chapters and Other Papers
BACKGROUND: Inadequate systemic exposure to infliximab (IFX) is associated with treatment failure. This work evaluated factors associated with reduced IFX exposure in children with autoimmune disorders requiring IFX therapy.
METHODS: In this single-center cross-sectional prospective study IFX trough concentrations and anti-drug antibodies (ADAs) were measured in serum from children diagnosed with inflammatory bowel disease (IBD) (n = 73), juvenile idiopathic arthritis (JIA) (n = 16), or uveitis (n = 8) receiving maintenance IFX infusions at an outpatient infusion clinic in a tertiary academic pediatric hospital. IFX concentrations in combination with population pharmacokinetic modeling were used to estimate IFX clearance. Patient …
Bmi And Associated Variables In A Pediatric Gender Clinic Sample, Mirae J. Fornander, Christine Moser, Anna Egan, Timothy A. Roberts
Bmi And Associated Variables In A Pediatric Gender Clinic Sample, Mirae J. Fornander, Christine Moser, Anna Egan, Timothy A. Roberts
Presentations
Background: Studies of transgender/gender diverse (TGD) youth indicate a high prevalence of overweight/obesity and concern for unhealthy weight control behavior.
Objective: Describe BMI and the association of medication use, well-being, and recreational activities in treatment-naïve pediatric TGD patients.
Design/Methods: Chart review of 302 patients (age 3-19, 73.5% sex assigned at birth (SAB) female; 85.8% white) from 2017-2020. BMI was calculated by age and SAB using CDC growth charts. Parents reported medication use; parent and self-reported Pediatric Quality of Life (PEDS-QL) Well-Being and activities were surveyed electronically.
Results: By BMI category, 3.3% were underweight (BMI<5%); 49.4% were >85% and 29.5% fell >95%. Overweight …5%);>
Utility Of Diagnostic Testing In Patients Who Present With Brief Resolved Unexplained Event, Allayne Stephans, Kathryn Westphal, Erin Sullivan, Matt Hall, Risa Bochner, Adam Cohen, Jennifer Y. Colgan, Atima C. Delaney, Amy Delaroche, Thomas Graf, Beth Harper, Ron L. Kaplan, Hannah C. Neubauer, Mark I. Neuman, Nirav Shastri, Victoria Wilkins, Joel S. Tieder, Manoj Mittal
Utility Of Diagnostic Testing In Patients Who Present With Brief Resolved Unexplained Event, Allayne Stephans, Kathryn Westphal, Erin Sullivan, Matt Hall, Risa Bochner, Adam Cohen, Jennifer Y. Colgan, Atima C. Delaney, Amy Delaroche, Thomas Graf, Beth Harper, Ron L. Kaplan, Hannah C. Neubauer, Mark I. Neuman, Nirav Shastri, Victoria Wilkins, Joel S. Tieder, Manoj Mittal
Presentations
Background: Well appearing infants commonly present with a history of a brief event characterized by changes in color, breathing, muscle tone, or level of alertness. In 1986 the National Institutes of Health coined the term ALTE (Apparent Life-Threatening Event) to describe these events. In 2016 the American Academcy of Pediatrics (AAP) published a guideline that updated the term ALTE to BRUE (Brief Resolved Unexplained Event). This guideline includes a more precise definition and limited recommendations for the evaluation of patients who are designated as lower risk for serious underlying diagnoses. A few small studies have examined the diagnostic yield of …
Use Of Clinical Criteria For Prediction Of Invasive Bacterial Infection In Febrile Infants: Evaluation Of The Pros Criteria, Lyubina Yankova, Mark Neuman, Marie Wang, Adrienne G. Deporre, Sanyukta Desai, Laura Sartori, Richard Marble, Lise Nigrovic, Rianna Leazer, Christopher Pruitt, Christopher Woll, Sahar Rooholamini, Frances Balamuth, Paul Aronson
Use Of Clinical Criteria For Prediction Of Invasive Bacterial Infection In Febrile Infants: Evaluation Of The Pros Criteria, Lyubina Yankova, Mark Neuman, Marie Wang, Adrienne G. Deporre, Sanyukta Desai, Laura Sartori, Richard Marble, Lise Nigrovic, Rianna Leazer, Christopher Pruitt, Christopher Woll, Sahar Rooholamini, Frances Balamuth, Paul Aronson
Presentations
Background: In a 2004 study, the American Academy of Pediatrics Pediatric Research in Office Settings (PROS) network developed clinical criteria that had a sensitivity of 93.6% for identification of febrile infants at low-risk for invasive bacterial infection (IBI). Although application of the PROS criteria would reduce routine testing and emergency department (ED) evaluation for febrile infants in outpatient settings without readily available access to laboratory testing, these criteria have not been externally validated in a contemporary cohort.
Objective: To evaluate the sensitivity of the PROS criteria for IBI in febrile infants ≤60 days old.
Design/Methods: We performed a secondary analysis …
Obesity Does Not Increase Risk For Kidney Replacement Therapy (Krt), But Weight Reduction Improves Kidney Function In Children With Chronic Kidney Disease (Ckd), Amy Kogon, J Roem, Mark Mitsnefes, Babette Zeme, Bradley A. Warady, Susan Furth, Nancy Rodig
Obesity Does Not Increase Risk For Kidney Replacement Therapy (Krt), But Weight Reduction Improves Kidney Function In Children With Chronic Kidney Disease (Ckd), Amy Kogon, J Roem, Mark Mitsnefes, Babette Zeme, Bradley A. Warady, Susan Furth, Nancy Rodig
Presentations
Background: Obesity is prevalent in pediatric CKD, but its impact on CKD progression is unclear.
Objective: To determine the relationship between obesity/weight changes with CKD progression among children and adolescents enrolled in the Chronic Kidney Disease in Children (CKiD) study.
Design/Methods: Participants were categorized based on body mass index (BMI) as normal, overweight (OW) or obese and those who were underweight were excluded. Kaplan-Meier survival curves and parametric failure time models determined the association of baseline BMI category on time to KRT stratified by non-glomerular (NG) and glomerular (G) etiology of CKD. The distribution of changes in BMI categories within …
Impact Of Covid-19 On Inpatient Utilization And Outcomes For Children With Medical Complexity, Jessica L. Markham, Troy Richardson, Adrienne G. Deporre, Ronald Teufel, Adam Hersh, Eric Feegler, Ryan Antiel, Adam Goldin, Arda Hotz, Jayme Wilder, Samir Shah
Impact Of Covid-19 On Inpatient Utilization And Outcomes For Children With Medical Complexity, Jessica L. Markham, Troy Richardson, Adrienne G. Deporre, Ronald Teufel, Adam Hersh, Eric Feegler, Ryan Antiel, Adam Goldin, Arda Hotz, Jayme Wilder, Samir Shah
Presentations
Background: Children with medical complexity (CMC) are a growing subpopulation of children who require intense engagement with the healthcare system including the involvement of multiple subspecialists and ancillary services. CMC often receive definitive care within children’s hospitals where subspecialty services are concentrated. While studies have reported reductions in emergency department visits and hospitalizations for generally healthy children during the COVID-19 pandemic, the overall impact of the pandemic on CMC has not been well described.
Objective: The objective of this study was to describe the impact of the early COVID-19 pandemic on inpatient utilization for CMC presenting to US children's hospitals. …
Contraception Counseling Of Adolescents Seeking Care In Pediatric Emergency Departments, Cynthia Mollen, Romina Barral, Tara Ketterer, Jungwon Min, Laurel Gabler, Lauren Poole, Amber Adams, Elizabeth Miller, Aletha Akers, Melissa K. Miller
Contraception Counseling Of Adolescents Seeking Care In Pediatric Emergency Departments, Cynthia Mollen, Romina Barral, Tara Ketterer, Jungwon Min, Laurel Gabler, Lauren Poole, Amber Adams, Elizabeth Miller, Aletha Akers, Melissa K. Miller
Presentations
Background: Efforts to increase contraceptive use among adolescents are urgently needed. One approach is to use clinical settings that do not routinely provide contraception services, such as the emergency department (ED). Though many are amenable to ED-based contraceptive care, best practices for providing this care are largely unexplored.
Objective: To assess intention to initiate contraception among adolescent females immediately after receiving ED-based contraceptive counseling, and to assess counseling feasibility, contraception initiation and completion of a follow-up visit for contraceptive care.
Design/Methods: Prospective cohort study in two urban pediatric EDs. Using webinar modules and in-person sessions, advanced practice providers (APPs) were …
Lessons From The Pandemic: How A Children’S Hospital Responded To The Challenges Of Covid-19, John Lantos, Paul Kempinski, Laurie Ellison, Jennifer Watts, Angela Myers
Lessons From The Pandemic: How A Children’S Hospital Responded To The Challenges Of Covid-19, John Lantos, Paul Kempinski, Laurie Ellison, Jennifer Watts, Angela Myers
Presentations
The COVID-19 pandemic challenged doctors and hospital administrators as did no other event in our lifetimes. Leaders needed to develop a pandemic command structure with the agility to respond to rapidly evolving situations. They had to deal with drastic financial implications, develop new methods of delivering health care, and collaborate regionally. They learned the importance of communication with staff, policy makers, the local medical community, and the public. They had to allocate of scarce resources internally and externally, and balancing rational policy making against irrational fears. For children’s hospitals, some specific challenges included determining our role in a pandemic that …
The Effect Of Covid-19 On The Detection And Prevalence Of Suicidality In Adolescents, John Lantos, Hung-Wen Yeh, Fajar Raza, Mark Connelly, Shayla Sullivant
The Effect Of Covid-19 On The Detection And Prevalence Of Suicidality In Adolescents, John Lantos, Hung-Wen Yeh, Fajar Raza, Mark Connelly, Shayla Sullivant
Presentations
Background: The COVID-19 pandemic saw changes to the delivery of health services and concerns about psychological morbidity not directly related to COVID infection. We analyzed the effects of the pandemic on our hospital’s program to screen adolescents for suicidality.
Objective: To determine the effect of the COVID-19 pandemic on 1) a hospital-wide screening program for suicidality in teens; and 2) the prevalence of positive screens for suicidality.
Design/Methods: Our study population was all patients > 12yo seen as inpatients or in the ED or clinics at a children’s hospital in Apr-June in 2019 (T1) and 2020 (T2). Eligible pts were screened …
Using Standardized Scripting To Improve Antibiotic Stewardship In A National Pediatric Urgent Care Collaborative, Amanda Nedved, Melody Fung, Cindy Liu, Rana Hamdy, Amanda Montalbano
Using Standardized Scripting To Improve Antibiotic Stewardship In A National Pediatric Urgent Care Collaborative, Amanda Nedved, Melody Fung, Cindy Liu, Rana Hamdy, Amanda Montalbano
Posters
Background: A study using administrative data reported urgent care providers as having the highest rates of inappropriate antibiotic use for upper respiratory illnesses. In a national survey, pediatric urgent care providers reported family expectations as a primary driver for prescribing inappropriate antibiotics. Standardized scripting has been effective at reducing unnecessary antibiotics while increasing family satisfaction.
Objective: To reduce inappropriate prescribing for upper respiratory infections (acute otitis media (AOM), otitis media with effusion (OME), and pharyngitis) in pediatric urgent cares by 20% by December 1, 2020 through use of standardized scripting in Year 2 of a national pediatric urgent care quality …
Pediatric Resident Reflections From A Non-Medical Home Visit Of A Child With Medical Complexity, Emily J. Goodwin, Sheryl Chadwick, Deejo Miller, Kathryn Taff, Amanda Montalbano
Pediatric Resident Reflections From A Non-Medical Home Visit Of A Child With Medical Complexity, Emily J. Goodwin, Sheryl Chadwick, Deejo Miller, Kathryn Taff, Amanda Montalbano
Posters
Background: Pediatric residents typically only interact with patients and families in healthcare settings which limits the opportunity to fully understand the patient and family experience. Encounters with children with medical complexity (CMC) that only relate to illness or health monitoring can anchor residents to false preconceptions and limit their ability to practice patient- and family-centered care (PFCC). The core principles of PFCC include acknowledging patient and family expertise and strengths, encouraging their input, and appreciating the value of their observations and perceptions.
Objective: To explore how a home visit program with patients and families serving as faculty could instill the …