Medical Specialties Commons^™

Perinatal Buprenorphine Effects On Offspring Growth, Opioid Withdrawal, And Brain Morphology In Rats, Parker Barnes

Electronic Theses and Dissertations

Opioid use disorder (OUD) impacts 5.6 million people in the US. Buprenorphine (BUP) is a commonly prescribed opioid medication used to treat OUD, including in pregnant women. However, opioid use during pregnancy is associated with poorer infant outcomes including reduced fetal growth, neurodevelopmental deficits, and neonatal opioid withdrawal syndrome (NOWS). Recent clinical data suggests that providing mothers with a lower dose of BUP may result in fewer negative outcomes in infants. Here, a preclinical rodent model of low-dose perinatal BUP exposure was used to study offspring health outcomes in the neonate, juvenile, and adolescent offspring. Dams were given clinically relevant …

Evaluating The Association Of Influenza Vaccination On Long-Term Covid-19 Symptoms In U.S. Adults, Ratnakar Pingili

Capstone Experience

Objective. To evaluate the association of influenza vaccination in the past 12 months with Long COVID effects and clinical and sociodemographic factors.

Methods. Cross-sectional study with data from the 2022 Behavioral Risk Factor Surveillance System (BRFSS), covering 415,132 non-institutionalized U.S. adults with a confirmed COVID-19 diagnosis and influenza vaccination reported within the last 12 months. Logistic regression was conducted between influenza vaccination (exposure) and Long COVID (outcome), controlling for demographic variables, pre-existing health conditions, and socioeconomic status.

Results. Of 120,603 participants, 21.89% reported Long COVID symptoms and 42.04% had received an influenza vaccine. Findings indicate a statistically significant 13% reduction …

A Multimodal Approach To Decreasing Hesitancy Of The Influenza Vaccine In The Family Care Setting, Carley J. Ellenberger

Evidence-Based Practice Project Reports

The uptake of the influenza vaccine is the most effective and proactive action an individual can take to defend themselves against the influenza outbreak each season; therefore, it is recommended that everyone at least six months of age and older should receive the annual flu vaccine (CDC, 2022; WHO, 2023). Unfortunately, influenza vaccine hesitancy is demonstrated on a global level affecting the uptake compliance annually each influenza season despite the millions of people that experience influenza symptoms annually (CDC, 2022, WHO, n.d.; Healthy People 2030, n.d.). The PICOT question for this project was in adults, over the age of 18, …

Phase Ib/Ii Study Of Lacnotuzumab In Combination With Spartalizumab In Patients With Advanced Malignancies, Jibran Ahmed, Bettzy Stephen, Yali Yang, Evan Kwiatkowski, Chinenye Lynette Ejezie, Shubham Pant

Journal Articles

INTRODUCTION: Blocking the colony-stimulating factor 1 (CSF-1) signal on tumor-associated macrophages can lead to an upregulation of checkpoint molecules, such as programmed cell death ligand 1 (PD-L1), thus causing resistance to this blockade. Combining spartalizumab (PDR001), a high-affinity, ligand-blocking, humanized anti-PD-1 immunoglobulin G4 antibody, with lacnotuzumab (MCS110), a high-affinity, humanized monoclonal antibody directed against human CSF-1 can potentially overcome this resistance.

METHODS: This was a multicenter, phase Ib/II trial using a combination of spartalizumab with lacnotuzumab in patients with advanced cancers, including anti-PD-1/PD-L1 treatment-resistant melanoma, and anti-PD-1/PD-L1 treatment-naïve triple-negative breast cancer, pancreatic cancer, and endometrial cancer (ClinicalTrials.gov identifier: NCT02807844). The …

Key Variants Via The Alzheimer's Disease Sequencing Project Whole Genome Sequence Data, Yanbing Wang, Chloé Sarnowski, Honghuang Lin, Achilleas N Pitsillides, Nancy L Heard-Costa, Seung Hoan Choi, Dongyu Wang, Joshua C Bis, Elizabeth E Blue, Eric Boerwinkle, Philip L De Jager, Myriam Fornage, Ellen M Wijsman, Sudha Seshadri, Josée Dupuis, Gina M Peloso, Anita L Destefano

Journal Articles

INTRODUCTION: Genome-wide association studies (GWAS) have identified loci associated with Alzheimer's disease (AD) but did not identify specific causal genes or variants within those loci. Analysis of whole genome sequence (WGS) data, which interrogates the entire genome and captures rare variations, may identify causal variants within GWAS loci.

METHODS: We performed single common variant association analysis and rare variant aggregate analyses in the pooled population (N cases = 2184, N controls = 2383) and targeted analyses in subpopulations using WGS data from the Alzheimer's Disease Sequencing Project (ADSP). The analyses were restricted to variants within 100 kb of 83 previously …

Relationship Between Food Security, Nutrition Security, And Diabetes: The Role Of Supplemental Nutrition Assistance Program Participation, Maha Almohamad, Jayna M Dave, Eric E Calloway, Ruosha Li, Shreela Sharma

Journal Articles

BACKGROUND: Inadequate nutrition and poor diet quality are associated with a heightened risk of diabetes. The connection between food insecurity measures and diabetes has been established, with evidence indicating that Supplemental Nutrition Assistance Program (SNAP) participation contributes to reductions in food insecurity. Recently developed nutrition security measures, defined as the ability to acquire healthful foods to prevent diseases, and their association with diabetes and SNAP participation are not yet understood.

OBJECTIVES: This study aimed to assess the relationship between food security and nutrition security in relation to diabetes overall and by SNAP participation and nutrition security as potential modifiers.

METHODS: …

The Effect Of Using A Meal Tracking Smartphone Application In Overweight And Obese Adolescents With Prediabetes Or Type 2 Diabetes To Improve Bmi And Hba1c, Lauren Torhorst

Evidence-Based Practice Project Reports

Obesity has become one of the most common chronic pediatric illnesses worldwide and is closely linked to the onset of prediabetes and subsequent Type 2 Diabetes (T2D); therefore, preventing and treating childhood obesity has become a high priority (Hampl et al., 2023). The purpose of this Evidence-Based Practice (EBP) project is to lower Glycosylated Hemoglobin A1c (HbA1C) and Body Mass Index (BMI) in overweight and obese youth with prediabetes and T2D using a meal tracking smartphone application. The Johns Hopkins Nursing Evidence-Based Practice Model (JHNEBP) was utilized to pilot this project between two pediatric endocrinology offices located in Southeast Wisconsin. …

A Mixed-Methods Study To Investigate Feasibility And Acceptability Of An Early Warning Score For Preterm Infants In Neonatal Units In Kenya: Results Of The News-K Study, Eleanor Mitchell, Jalemba Aluvaala, Lucy Bradshaw, Jane Daniels, Caren Emadau, Bernadine Muthumbi, Helen Nabwera, Ednah Ojee, Jacqueline Opira, Phoebe Pallotti

Centre of Excellence in Women and Child Health

Preterm birth (< 37 weeks gestation) complications are the leading cause of neonatal mortality. Early-warning scores (EWS) are charts where vital signs (e.g., temperature, heart rate, respiratory rate) are recorded, triggering action. To evaluate whether a neonatal EWS improves clinical outcomes in low-middle income countries, a randomised trial is needed. Determining whether the use of a neonatal EWS is feasible and acceptable in newborn units, is a prerequisite to conducting a trial. We implemented a neonatal EWS in three newborn units in Kenya. Staff were asked to record infants’ vital signs on the EWS during the study, triggering additional interventions as per existing local guidelines. No other aspects of care were altered. Feasibility criteria were pre-specified. We also interviewed health professionals (n = 28) and parents/family members (n = 42) to hear their opinions of the EWS. Data were collected on 465 preterm and/or low birthweight (< 2.5 kg) infants. In addition to qualitative study participants, 45 health professionals in participating hospitals also completed an online survey to share their views on the EWS. 94% of infants had the EWS completed at least once during their newborn unit admission. EWS completion was highest on the day of admission (93%). Completion rates were similar across shifts. 15% of vital signs triggered escalation to a more senior member of staff. Health professionals reported liking the EWS, though recognised the biggest barrier to implementation was poor staffing. Newborn unit infant to staff ratios varied between 10 and 53 staff per 1 infant, depending upon time of shift and staff type. A randomised trial of neonatal EWS in Kenya is possible and acceptable, though adaptations are required to the form before implementation.

Sars-Cov-2 Viral Load In The Nasopharynx At Time Of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis Of 4 Randomized Trials, Leigh H Fisher, Jia Jin Kee, Albert Liu, Claudia M Espinosa, April K Randhawa, James Ludwig, Craig A Magaret, Samuel T Robinson, Peter B Gilbert, Ollivier Hyrien, James G Kublin, Nadine Rouphael, Ann R Falsey, Magdalena E Sobieszczyk, Hana M El Sahly, Beatriz Grinsztejn, Glenda E Gray, Karen L Kotloff, Cynthia L Gay, Brett Leav, Ian Hirsch, Frank Struyf, Lisa M Dunkle, Kathleen M Neuzil, Lawrence Corey, Yunda Huang, Paul A Goepfert, Stephen R Walsh, Lindsey R Baden, Holly Janes, Covid-19 Prevention Network (Covpn)

Journal Articles

Importance: SARS-CoV-2 viral load (VL) in the nasopharynx is difficult to quantify and standardize across settings, but it may inform transmission potential and disease severity.

Objective: To characterize VL at COVID-19 diagnosis among previously uninfected and unvaccinated individuals by evaluating the association of demographic and clinical characteristics, viral variant, and trial with VL, as well as the ability of VL to predict severe disease.

Design, setting, and participants: This secondary cross-protocol analysis used individual-level data from placebo recipients from 4 harmonized, phase 3 COVID-19 vaccine efficacy trials sponsored by Moderna, AstraZeneca, Janssen, and Novavax. Participants were SARS-CoV-2 negative at baseline …

Prophylactic Surgical Wound Management With Negative Pressure Therapy In Emergency Abdominal Surgery: Is It Really Useful?, Yelson Alejandro Picón Jaimes, Samir Alberto Caycedo Assia, Isabela Zenilma Daza Patiño, Eliecer Enrique Aragon Acosta, Cindy Stephanie Buitrago Almanza

Revista de la Facultad de Medicina Humana

Mr Editor Infection at the operating site (ISO) is the most common postoperative surgical complication in general surgery. This is more frequent in cases of emergency interventions, compromises the patient's prognosis, causes high health costs, and signicantly increases the risk of reintervention. Negative pressure therapy (NPT) is an innovative strategy that was proposed about two decades ago, and has been gradually replicated around the world. This means that there are still many gaps in the evidence when it is used in many diseases and under different contexts. Nevertheless, it allows obtaining conclusive results in the time of healing, reduction of …

Gastrointestinal Stromaal Tumor (Gist) In The Jejunum, Jose Mantilla, Alessandra Canelo, Alejandro Llanos-Salirrosas, Elver López, Lucero Mejía, Sharon Polo

Revista de la Facultad de Medicina Humana

Gastrointestinal stromal tumors (GIST) are mesenchymal neoplasms that represent less than 3% of gastrointestinal neoplasms, with an incidence of 1 to 2 cases per hundred thousand inhabitants. It originates more frequently in the stomach and small intestine and is characterized by the expression of the tyrosine kinase growth factor receptor, CD117. Therefore, its diagnosis requires an immunohischemical study to rule it out from other mesenchymal tumors. However, enteroscopic imaging and analysis of the biopsy may suggest a preoperative diagnosis of probable GIST. The case of a 62-year-old woman with rectorrhagia and recurrent anemia caused by mid-intestinal bleeding observed by capsule …

Nongenetic Causes Of Hypertyrosinemia That Must Be Considered When Interpreting A Finding Of Elevated Urinary Tyrosine, Manuel André Virú-Loza

Revista de la Facultad de Medicina Humana

Mr. Editor. In several countries, newborns are screened for tyrosinemia type 1 using tyrosine as a primary marker. In some situations, elevated blood tyrosine levels are discovered due to elevated tyrosine on a urine metabolic screen. In Peru, some pediatric patients suspected of having a genetic condition (inborn error of metabolism) undergo a metabolic screening in urine that includes - among other things - the qualitative detection of tyrosine. However, when there are high levels of tyrosine in the urine this does not always mean that the patient has a genetic condition. Hypertyrosinemia is most often non-genetic in origin. Therefore, …

Acute Pneumonitis After Subcutaneous Injection Of Bio-Alcamid® In Breast, Renzo Villanueva-Villegas, Anita Trigoso-Gutiérrez, Piero Castillo-Gutierrez, Juan Salas-López

Revista de la Facultad de Medicina Humana

Filling materials are used to correct soft tissue deficits. Local and systemic complications are described when these substances are applied. The polyalkylamide gel (Bio-alcamid) used as filler material has been associated with complications at the facial level, while at the pulmonary level they have not been reported in the literature. We present the case of a patient who consulted due to sudden progressive dyspnea hours after the subcutaneous injection of Bio-alcamid in the breasts. After the clinical evaluation and the result of auxiliary tests, the diagnosis of acute pneumonitis secondary to the injection of this substance is concluded. Follow-up of …

Ghost Cell Glaucoma: Clinic Case, Diego José Mamani Maquera, Nahuel Pantoja Dávalos

Revista de la Facultad de Medicina Humana

Introduction: Ghost cell glaucoma (GCG) is a very rare secondary open angle glaucoma, in which there is a sustained increase in intraocular pressure (IOP) due to obstruction of the trabecular meshwork (TM) due to the passage of ghost cells (GC) from the vitreous into the anterior chamber, after a vitreous hemorrhage (VH). Clinical Case: We present the case of a male patient with a history of vitreous hemorrhage and sustained IOP elevation in the right eye (RE). Medical treatment was insufficient, for this reason surgical treatment was required. Postoperative evolution was favorable. Conclusion: This pathology should prefer the differential diagnosis …

Small Bowel Arteriovenous Malformation As A Cause Of Dark Gastrointestinal Bleeding: Two Instructional Cases, Eugenio Américo Palomino Portilla, María Del Pilar Quiñones Ávila, Isaira Giovanna Torpoco Baquerizo, María Angélica Medrano Huallanca, Katia Sofía Palomino Aguilar

Revista de la Facultad de Medicina Humana

Introduction: Digestive bleeding can put patients’ lives at risk, even more so when the origin is not located in routine upper and lower endoscopy. The small intestine is the largest portion of the digestive tract and being a source of bleeding means a diagnostic and therapeutic medical challenge. Clinical case: We presented cases of two female patients, 53 and 60 years old, who develop digestive bleeding, locating its origin in the small bowel and undergoing surgical removal of the affected intestinal segment. The anatomopathological study finds malformed arteries and veins that communicate without an intermediate capillary bed. The diagnosis was …

Pharmacological Efficacy Of Aloe Vera In Wound Healing: A Narrative Review, Sandra Viviana Aparicio Salcedo, Brian Steven Carranza Aldana, Sayuri Anayca Chávez Salas, Leslie Solanth Quispe Tinco, Carlos Abel Palomino Zevallos, Ariana Nicole Peralta Medina, Juana Mónica Robles Esquerre

Revista de la Facultad de Medicina Humana

Aloe Vera has different therapeutic effects, including wound healing. The aim of this review is to determine the potential efficacy of topical use of Aloe Vera in skin wound healing. A bibliographic search of preclinical and clinical studies from 1999 to 2020 was carried out, which included the therapeutic use of Aloe vera in the healing of: burns, surgical wounds, lactation disorders, anal fissure and anal fistula; in the databases of the VHL Regional Portal, PubMed and Google Scholar. It was obtained that the topical administration of Aloe vera was effective in the healing of the mentioned wounds by mainly …

Seawater Products For Nasal Lavages. Comparison And Literature Review, Irene López Barea, Luis Molini Cabrera, Manuel Enrique García Falcón, Cristóbal Coronel Rodríguez

Revista de la Facultad de Medicina Humana

Introduction. There is a wide range of seawater products for nasal lavages. Their efficacy and superiority over conventional saline solutions are not well established. Objectives. To analyse the best-selling seawater products, as well as reviewing the most recent literature regarding nasal lavages. Methods. Comparative study of composition, administration mode, age indicated for its use, price and bibliography provided on the web of the seawater products usually available in pharmacies. Analysis of the bibliography provided and review of the scientific evidence regarding nasal lavages with saline solutions or seawater. Results. 44 products from 11 manufacturers were analysed. The concentration of sodium …

Identification Of Human Papillomavirus Genotypes In Juvenile Laryngeal Papillomatosis. Three-Year Experience In A Concentration Hospital In Puebla, Mexico, Arturo García-Galicia, Clotilde Margarita Andrade-Bonilla, Verónica Vallejo-Ruiz, Blanca Elena Vallejo-Domínguez, Janeth Ramírez-Mendoza, Álvaro José Montiel-Jarquín, Nancy Rosalía Bertado-Ramírez, Jorge Loría-Castellanos

Revista de la Facultad de Medicina Humana

Background: Juvenile laryngeal papillomatosis (JLP) is a chronic benign disease from viral etiology, whose clinical course can be aggressive. In Mexico, the Human Papillomavirus (HPV) genotypes that cause this disease have been poorly studied. Objective: To identify the HPV genotypes in patients with JLP in a reference Hospital in Puebla, Mexico. Mehods: A retrospective descriptive study was performed in patients with JLP attended in a 3rd level care of the Instituto Mexicano del Seguro Social in Puebla, México, from 2018 to 2021. Medical records were revised. In all patients, HPV identification was performed by polymerase chain reaction for genomes 6, …

Consumption Of Foods Rich In Antioxidants In Outpatients With Diabetic Retinopathy At Hospital La Carlota During 2021, Raquel Martínez De Kurata, Raquel Karen García Lecca, Edward Samudio Márquez, Javier Castillo Velázquez

Revista de la Facultad de Medicina Humana

The objective of this work was to assess the quality of the consumption of foods rich in antioxidants such as vitamin C, E and selenium, in a sample of 28 patients with diabetic retinopathy (DR) who attended outpatient consultation at the Institute of Vision, of the La Carlota Hospital, in February 2021. The research was observational, descriptive, cross-sectional, with an analytical component. Patients older than 20 years with DR were included, who agreed to participate in the food survey applied by hospital professionals. Sociodemographic and ophthalmological variables and food consumption were measured. Results: 60% of the cases were men, the …

Factors Associated With Post-Delivery Complications, According To The Demographic And Family Health Survey In Perú 2019-2020, Kimberley Lissette Mauricio-Fernández, Rubén A. Huamán Santos, Rubén Espinoza Rojas

Revista de la Facultad de Medicina Humana

Introducción: Las complicaciones post parto son problemas de salud importante en el Perú, por lo tanto, es necesario determinar sus factores asociados. Objectives. To determine the factors associated with complications after childbirth in women aged 12 to 49 years in Peru, according to the demographic and family health survey, 2019-2020. Methods. Secondary source study based on the ENDES 2019-2020. The unit of analysis was all women aged 12 to 49 years residing in Peru in the years 2019-2020, who presented postpartum complications, and who answered the questions of the study variables. Results. It is evidenced that the age of 20 …

Identification Of Palliative Care Requirement In Hospital Inpatients In Internal Medicine Services In A Peruvian Reference Hospital, Annie Velasquez-Manrique, Claudia Benavides-Luyo, Susan Chaupi-Rojas, Sandra Andahua-Inuma, Manuel Andrade-Acuña, Rubén Sánchez-Ruiz, Alonso Soto

Revista de la Facultad de Medicina Humana

Introduction: Hospitals of greater complexity tend to care for patients with advanced chronic diseases, which is why it is important to recognize the need for palliative care. Objective: To identify the proportion of patients who require palliative care in the medicine department of a Peruvian referral hospital. Methods: Observational, analytical, cross-sectional study. All hospitalized patients were studied in the Department of Internal Medicine of the Peruvian hospital during the period April-May 2018. To determine the need for palliative care, the NECPAL CCOMS-ICO © instrument was used. The quantitative variables are presented as median and interquartile range (IQR); and numerical variables, …

Academic Interest In The Therapeutic Use Of Cannabis In Nursing Students From A Private University In Chile, Alejandro Antonio Hernández Diaz

Revista de la Facultad de Medicina Humana

Introduction: Cannabis therapeutic use is increasingly prominent.Objective: To identify the academi interested related to the therapeutic use of cannabis in nursing students. Methods: It is an investigation from Gadamer's hermeneutical paradigm. The non-probabilistic sample of cases by criteria was made up of 20 key informants from the 3rd and 4th years of the Nursing Career; inclusion criteria: be a student enrolled in the school year and be up to date on the degree. Data collection was through the formation of two focus groups in 2018. Data reduction was manual, data transcription was performed using the Jefferson formula, rigorous and ethical …

Factors Associated With Hemoglobin Levels In Children Under 6 Months Of Age Hospitalized In A Pediatric Center In Peru, Víctor Alfonso Mamani-Urrutia, Rafael Durán-Galdo, Carlos Gonzales-Saravia, Alicia Bustamante-López, Rubén Espinoza-Rojas, Raffo Escalante-Kanashiro

Revista de la Facultad de Medicina Humana

Introduction: Anemia is a condition in which there is a low concentration of hemoglobin (Hb) levels. Although many causes of anemia have been identified, there are few studies in which they are related to epidemiological factors in the first months of life. Objective: To determine the factors associated with hemoglobin levels in children under 6 months of age hospitalized in a specialized pediatric center in Peru. Methods: To determine the factors associated with hemoglobin levels in children under 6 months of age hospitalized in a specialized pediatric center in Peru. Results: 61.4% of the infants were women, and only 6.7% …

Computer Visual Syndrome In Medical Students In Virtual Education Of A Peruvian University During 2021, Rosario Mercedes Meneses Castañeda, Sergio Luis Ramos Rodriguez, Chiara Del Carmen Molfino Jaramillo, Ely Luisa Sánchez Miraval, David Francisco Stein Montoro, Lourdes Guissel Chávez Rodríguez

Revista de la Facultad de Medicina Humana

Introduction: During virtual classes in the context of COVID-19, students were exposed to digital screens for many hours, so they could present computer vision syndrome. Objective: To determine the frequency of computer vision syndrome in sixth-year medical students at Ricardo Palma University during virtual education due to COVID-19 in October and November 2021. Methods: Cross-sectional descriptive study in 147 sixth-year medical students who received virtual education at a Peruvian university during 2021. A non-probability sampling was used for convenience and the SVI was evaluated with the SVI-Q questionnaire, in addition characteristics were evaluated. demographics, visual preventive measures and eye diseases. …

Important Advances In Regenerative Medicine. A Vision To The Future Of Ophthalmology, Rafael Iván Hernández, Eduardo Alan Borobio Guede, Catherine Suárez Egóavil, Jhony A. De La Cruz-Vargas

Revista de la Facultad de Medicina Humana

The treatment of corneal lesions continues to be a topic of great interest. However, despite the development of new technologies and due to the slow evolution and uncertain healing of corneal lesions, they still represent a public health problem since patients can be affected for life, affecting the family and the health system due to the costly and uncertain response to treatment. For this reason, the need arises to seek therapeutic alternatives to treat these patients.

Management Indicators In Research 2022 Inicib-Urp, Jhony A. De La Cruz-Vargas, Dante Quiñones-Laveriano

Revista de la Facultad de Medicina Humana

Given the importance of the research component to respond to phenomena and problems demanded by society , At Universidad Ricardo Palma, research has been fostered and promoted as an institutional policy. The Instituto de Investigación en Ciencias Biomédicas, which reports to the Rectorate and is integrated into the Facultad de Medicina Humana, has been working to contribute substantially to this growth in research. The research is directly related to the quality processes of higher education, innovation, extension, linking, licensing, accreditation, and finally, the ranking of universities. As is evident, the research is linked to the present and the future of …

Observational Analysis For Predicting Initial Spikes In Testing Volume Of Cohorts Inside And Outside Of A Regional Covid-19 Screening Program, Adam M. Franks, Seth Bergeron, Tammy Bannister, Justin Spradling, Tamara Lowe, Paris Johnson, Rajan Lamichhane, Stephen M. Petrany

Marshall Journal of Medicine

BACKGROUND Containing the highly contagious SARs-CoV-2 pathogen requires a safe and effective screening program. The aim of this observational cohort study is to analyze a regional testing center and identify factors predicting testing rates that direct supply and staffing needs.

METHODS A drive-through SAR-CoV-2 regional testing facility was created. Number of tests and positive results were collected for eighteen months. Data for testing demand was compared to positive results, percent positive rates (PPR), known external factors, and county PPR. Dissimilarities were contrasted with dynamic time warp and a detailed agreement analysis. The Grainger’s test was utilized to assess the degree …

What Is The Additive Value Of Nutritional Deficiency To Va-Fi In The Risk Assessment For Heart Failure Patients?, Seulgi Erica Kim, Mehrnaz Azarian, Aanand D Naik, Catherine Park, Molly J Horstman, Salim S Virani, Orna Intrator, Christopher I Amos, Ariela Orkaby, Javad Razjouyan

Journal Articles

OBJECTIVES: to assess the impact of adding the Prognostic Nutritional Index (PNI) to the U.S. Veterans Health Administration frailty index (VA-FI) for the prediction of time-to-death and other clinical outcomes in Veterans hospitalized with Heart Failure.

METHODS: A retrospective cohort study of veterans hospitalized for heart failure (HF) from October 2015 to October 2018. Veterans ≥50 years with albumin and lymphocyte counts, needed to calculate the PNI, in the year prior to hospitalization were included. We defined malnutrition as PNI ≤43.6, based on the Youden index. VA-FI was calculated from the year prior to the hospitalization and identified three groups: …

Educating Nurses On Frequent Oral Care For Mechanically Ventilated Patients: An Evidence-Based Practice Project Proposal, Grace Alford, Susan Butz, Ruth Chavez, Joy Shoemaker

Doctor of Nursing Practice Scholarly Projects

The final scholarly project proposal is to implement oral care education for nurses in an intensive care unit (ICU). The proposal aims to create a guideline for an investigator to implement oral care recommendations for mechanically ventilated patients in order to reduce ventilator-associated pneumonia (VAP). The proposal consists of obtaining VAP data and oral care charting data for the unit studied, steps for providing oral care education, and analysis recommendations. Oral care involves swabbing the patient’s mouth every two hours with a swab and mouthwash. Oral care education would include handouts and direct teaching. The proposal aims to increase oral …

An Expanded Chronic Care Management Approach To Multiple Chronic Conditions In Hispanics Using Community Health Workers As Community Extenders In The Rio Grande Valley Of Texas, Juliana Z Lopez, Minjae Lee, Soo K Park, Maria E Zolezzi, Lisa A Mitchell-Bennett, Paul G Yeh, Lubeth Perez, Natalia I Heredia, David D Mcpherson, Joseph B Mccormick, Belinda M Reininger

Journal Articles

INTRODUCTION: The synergistic negative effects of type 2 diabetes (T2DM) and hypertension increases all-cause mortality and the medical complexity of management, which disproportionately impact Hispanics who face barriers to healthcare access. The Salud y Vida intervention was delivered to Hispanic adults living along the Texas-Mexico Border with comorbid poorly controlled T2DM and hypertension. The Salud y Vida multicomponent intervention incorporated community health workers (CHWs) into an expanded chronic care management model to deliver home-based follow-up visits and provided community-based diabetes self-management education.

METHODS: We conducted multivariable longitudinal analysis to examine the longitudinal intervention effect on reducing systolic and diastolic blood …