Medical Specialties Commons^™

Current Concepts In The Diagnosis And Management Of Childhood Asthma, Z A. Bhutta

Department of Paediatrics and Child Health

No abstract provided.

Transcutaneous Bilirubinometry In Pakistani Newborns: A Preliminary Report, Z A. Bhutta, K Yusuf

Department of Paediatrics and Child Health

Neonatal hyperbilirubinemia is a frequently encountered problem in the neonatal period and carries a potential risk of encephalopathy. Early detection and quantification is important, and transcutaneous bilirubinometry (TcB) has been recommended as a non-invasive method for rapid screening. We prospectively compared the efficacy of TcB in 65 normal Pakistani jaundiced newborns undergoing simultaneous serum bilirubin measurements. Although the correlation between the two methods was significant (r = 0.66, P less than 0.01), the scatter was wide and the specificity only 53%. Although the technique offers the potential for non-invasive early screening of neonatal hyperbilirubinemia, it requires further validation in a …

Fulminant Hepatic Failure With Typhoid Fever In Childhood, Z A. Bhutta

Department of Paediatrics and Child Health

Although hepatic dysfunction has been described among adults with typhoid, there are few reports of significant hepatic functional impairment in children with typhoid. Of 355 children with culture proven typhoid seen at the Aga Khan University Hospital, hepatomegaly was noted in 118 (33%) and isolated right hypochondrial tenderness in 30 (8.5%). The liver function tests were normal in 78% and 47% of these children respectively and significant hepatic dysfunction was seen only in 26 (7.3%). However, children with typhoid and significant hepatic dysfunction had higher mortality (P less than 0.001) and two patients presented with a picture of fulminant hepatic …

Successful Eradication Of Flavobacterium Meningosepticum Neonatal Meningitis With Ceftizoxime, Z A. Bhutta, S H. Naqvi

Department of Paediatrics and Child Health

No abstract provided.

Chloramphenicol Therapy Of Typhoid Fever, Z A. Bhutta, S H. Naqvi, S Durrani, A Suria

Department of Paediatrics and Child Health

In a prospective study we compared two different dosage regimens of IV chloramphenicol succinate (100 mg/kg/day and 75 mg/kg/day) in children with culture proven typhoid. Trough and peak blood samples, obtained at 48 hrs, were analysed for free chloramphenicol by high pressure liquid chromatography (HPLC). Although the mean trough (8.8 +/- 7.7 versus 5.4 +/- 2.6 mcg/ml) and peak (19.9 +/- 12.2 versus 15.4 +/- 6.1 mcg/ml) chloramphenicol concentrations were comparable in both groups, a significantly wider range was found in the group receiving 100 mg/kg/day. Potentially toxic levels (greater than 30 mcg/ml) developed in two patients with liver dysfunction. …

Malignant External Otitis And Mastoiditis Associated With An Igg4 Subclass Deficiency In A Child., Ricardo Castro, Md, Norman Robinson, Md, Joel Klein, Md, William Geimeier, Md

Department of Pediatrics Faculty Papers

We have presented the first child in Delaware with malignant external otitis associated with IgG4 deficiency. Our patient needed three courses of intravenous antibiotics and twice required mastoidectomy, but has recovered completely following the restoration of the natural barrier between the internal and external ear, using a fascial graft from the large temporalis muscle. Some hearing deficit remains.

Ua35/11 Student Honors Research Bulletin, Wku Honors Program

WKU Administration Documents

The WKU Student Honors Research Bulletin is dedicated to scholarly involvement and student research. These papers are representative of work done by students from throughout the university.

• Basham, Penny. The Ritalin Controversy: Hyperactive Children and Medication
• Buote, Kim. The Transmission of Negative Feedback: Obstacles, Effects and Suggestions
• Cowan, James. The 1988 Presidential Primaries: Search for Bandwagons
• Durfey, Suzanne. AIDS: Nutrition and Its Implications
• Felty, Jeff. Gay and Lesbian Couples
• Gilliland, Linda. Muffins and Aspartame or Sucrose
• Graham, Ken. Sudden Infant Death Syndrome
• Grubbs, Morris. Conflicts and Synthesis in Robert Penn Warren's Blackberry Winter
• Medeiros, Lynne. Problems of Democratic Republicism in …

Recurrent/Persistent Pneumonia In A 3 1/2-Year-Old-Girl Due To Acquired Immune Deficiency Syndrome., Ricardo Castro, Md, Joel Klein, Md, Rajeswary Padmalingam, Md, Stephen C. Eppes, Md

Department of Pediatrics Faculty Papers

The following is the report of the first case of a Delaware born child who developed AIDS, born from a mother who was not in a high risk camp.

Maternal-Neonatal Serum Vitamin A Concentrations., Girish S. Shirali, D G. Oelberg, K P. Mehta

Manuscripts, Articles, Book Chapters and Other Papers

Prevention of neonatal vitamin A deficiency is related to the adequacy of maternal vitamin A stores. In this study we investigated maternal and cord serum vitamin A and retinol-binding protein (RBP) values in an Indian population including, for the first time, clinically vitamin A-deficient mothers. Twenty-eight maternal-neonatal pairs were selected from maternal cohorts of high socioeconomic status without clinical evidence of vitamin A deficiency (group I) and low socioeconomic status with conjunctival xerosis and Bitot's spots (group II). Maternal education, caloric and vitamin A intakes, weight, height, hemoglobin, and birth weight were significantly lower in group II. Serum vitamin A …

Animal Bite Infections., Joel D. Klein, Md

Department of Pediatrics Faculty Papers

Animal bites have become alarmingly common and may represent a quiet epidemic. It is estimated that between 1 and 3.5 million animal bites occur annually in the United States. The highest incidence has consistently been in 5-to-14-year-old schoolchildren, who have greater contact with animals, especially house pets, on a daily basis. This article discusses the epidemiology, microbiology, clinical findings and management of animal bites infections.

Neonatal Screening For Congenital Hypothyroidism In Pakistan, Murntaz Lakhani, Mohammad Khurshid, Shehla H. Naqvi, Mohammad Akber

Department of Paediatrics and Child Health

Congenital hypothyroidism is a preventable cause of mental retardation. Since clinical signs of congenital hypothyroidism do not generally become obvious before three months of age, screening programmes have been introduced in North America and Europe, which consist of T4 or TSH screening on newborn infants on the third day of life. The screening for congenital hypothyroidism was initiated in Pakistan by the Aga Khan University Hospital (AKUH) in March 1987. By April 1988, 5000 neonates were screened and five cases of congenital hypothyroidism were diagnosed. The study revealed the incidence of hypothyroidism to be one case per 1000 newborns which …

Prediction Of Intellectual Deficits In Children With Acute Lymphocytic Leukemia, Paul Trautman, Candace Erickson, David Shaffer, Patricia O'Connor, Annaliese Sitarz, Antonio Correra, Irvin Sam Schonfeld

Publications and Research

Possible predictors of reported lower cognitive functioning in irradiated children with acute lymphoblastic leukemia (ALL) were investigated. Thirty-four subjects, 5-14 years old, with ALL in continuous complete remission and without evidence of current or past central nervous system disease, were examined 9-110 months after diagnosis, using standard measures of intelligence and academic achievement. Subjects with a history of post-irradiation somnolence syndrome were significantly older at diagnosis than nonsomnolent subjects. Intelligence (IQ) was found to be unrelated to history of somnolence syndrome. IQ and achievement were unrelated to age at irradiation, irradiation-examination interval, and radiation dosages. The strongest predictor of IQ …

[Review Of] The New Child Health Encyclopedia: The Complete Guide For Parents, Robert A. Aken

Library Faculty and Staff Publications

No abstract provided.

Comparison Of Intermediate-Dose Methotrexate With Cranial Irradiation For The Post-Induction Treatment Of Acute Lymphocytic Leukemia In Children, Arnold I. Freeman , M.D., Vivian Weinberg, Martin L. Brecher , M.D., Barbara Jones , M.D., Arvin S. Glicksman , M.D., Lucius F. Sinks , M.D., Marise Weil , M.D., Hansjuerg Pleuss , M.D., Juliet Hananian , M.D., E. Omer Burgert , Jr., M.D., Gerald S. Gilchrist , M.D., Thomas Necheles , M.D., Michael Harris , M.D., Faith Kung , M.D., Richard B. Patterson , M.D., Harold Maurer , M.D., Brigid Leventhal , M.D., Louise Chevalier , M.D., Edwin Forman , M.D., James F. Holland , M.D.

Pediatrics Publications

Abstract

We compared two regimens with respect to their ability to prolong disease-free survival in 506 children and adolescents with acute lymphocytic leukemia. All responders to induction therapy were randomized to treatment with 2400 rad of cranial irradiation plus intrathecal methotrexate or to treatment with intermediate-dose methotrexate plus intrathecal methotrexate, as prophylaxis for involvement of the central nervous system and other "sanctuary" areas. Patients were then treated with a standard maintenance regimen. Complete responders were stratified into either standard-risk or increased-risk groups on the basis of age and white-cell count at presentation.

Among patients with standard risk, hematologic relapses occurred …

Pediatrics, Susan P. Dunkley

UND Departmental Histories

This departmental history was written on the occasion of the UND Centennial in 1983.

Treatment Of Inborn Errors Of Urea Synthesis — Activation Of Alternative Pathways Of Waste Nitrogen Synthesis And Excretion, Mark L. Batshaw , M.D., Saul Brusilow , M.D., Lewis Waber , Ph.D., M.D., Wim Blom , Ph.D., Ann Mari Brubakk , M.D., Barbara K. Burton , M.D., Howard M. Cann , M.D., Douglas Kerr , M.D., Peter Mamunes , M.D., Reuben Matalon , M.D., David Myerberg , M.D., Irwin A. Schafer , M.D.

Pediatrics Publications

Abstract

Children with inborn errors of urea synthesis accumulate ammonium and other nitrogenous precursors of urea, leading to episodic coma and a high mortality rate. We used alternative pathways for the excretion of waste nitrogen as substitutes for the defective ureagenic pathways in 26 infants. These pathways involve synthesis and excretion of hippurate after sodium benzoate administration, and of citrulline and argininosuccinate after arginine supplementation.

The children were treated for seven to 62 months; 22 survived. The mean plasma level of ammonium (±S.E.) was 36±2 μmol per liter, and that of benzoate was 1.5±1.0 mg per deciliter. Alternative pathways accounted …

Visual And Auditory Attention In Hyperactive And Normal Boys, Ronald T. Brown

Integrated Health Sciences Faculty Research

No abstract provided.

Remediation Efforts For Hyperactivity: Training In Attention Or Inhibitory Control, Ronald T. Brown

Integrated Health Sciences Faculty Research

No abstract provided.

Survey Of Pediatricians : What Are The Criteria Used For Referral To Speech And Language Pathologists?, Janet Bradley

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of the present research was to summarize from the pediatric literature the norms for speech and language development and to determine if the pediatrician is utilizing these norms as criteria for making referrals to speech and language pathologists. Research tends to show a discrepancy between the incidence of speech and language disorders and the rate of referrals made by physicians.

The methodology involved developing a three-part questionnaire to determine what screening instruments are being used in the pediatric office in regard to speech, language, and hearing, and what informal criteria are utilized for making referrals for a speech …

Some Misgivings About Locus Of Control Orientation And Its Relationship To Intelligence, Academic Achievement, And Delinquency, Ronald T. Brown

Integrated Health Sciences Faculty Research

No abstract provided.

Modeling: A Cognitive Approach In Ameliorating Impulsivity In Hyperactive Children, Ronald T. Brown

Integrated Health Sciences Faculty Research

No abstract provided.

A Developmental Analysis Of Attentional Processes In Educabley Mentally Retarded And Normally Developing Children, Ronald T. Brown

Integrated Health Sciences Faculty Research

No abstract provided.

Solid Tumors In Children, Harold M. Maurer , M.D.

Pediatrics Publications

No abstract provided.

Children With Porencephaly: A Study Of Services, Dana Kaufman, Elisabeth Mason

Dissertations and Theses

This study was conducted to serve as a follow-up of services received and/or needed by families with children who have been identified by Crippled Children's Division of the University of Oregon Health Sciences Center as having porencephaly, usually a severe form of brain damage. Porencephaly refers to cystic cavities or lesions in the brain caused by a prenatal insult to the brain resulting in varying degrees of motor and mental deficits. These children have been seen in general as part of the Cerebral Palsy Clinic. There may be a lack of awareness on part of the parents and the staff …

Ua68/10/1 Sociological Symposium No. 8 – Childbirth & Infancy Life Cycle Series, Wku Sociology

WKU Administration Documents

Table of Contents:

• Hernandez, Pedro F. Catholic Church & Birth Control in Latin America
• Kovit, Leonard. Labor is Hard Work: Notes on the Social Organization of Childbirth
• McNurlen, Lewis J. Childbirth: A Family Affair
• Miller, Rita Seiden & Ron Miller. Social Values Supporting Pregnancy: Dilemma for Population Control
• Newman, John F. & William L. Graves. Neo-Natal Mortality & Socio-Economic Status
• Newman, Lucille F. The Anthropology of Birth
• Rutzen, S. Robert. Urban Life & Breast Feeding: A Sociological Analysis
• Schulz, Barbara & Richard Schulz. Family Size Preferences & Sex Composition
• Steinhoff, Patricia G., Roy G. Smith & Milton Diamond. Characteristics & …

Hyperactivity In Children, Pat Luttmann

Student Scholarship

The provided document, written in 1971, explores the multifaceted nature of hyperactivity in children, primarily within the framework of minimal brain dysfunction or MBD. The author notes that while these children often appear physically normal, they struggle with a disorganized central nervous system that prevents them from processing environmental stimuli effectively. This neurological impairment manifests as a cluster of symptoms, most notably hyperkinesis, distractibility, impulsiveness, and emotional instability. The text emphasizes that the number of children identified with these disorders is increasing, partly due to medical advances that allow more children to survive difficult births. 

Diagnosis and treatment require a …

The Effects Of Prenatal Amphetamine Administration On Activity And The Levels Of Brain Catecholamines In Young Mice, Ann Blackwell

MUSC Theses and Dissertations

C5713L/6J mice were injected with D-amphetamine sulfate for the last six days of gestation. Their offspring were compared with those of saline-injected and untreated controls. Although the amphetamine-treated mothers gained less weight than controls during treatment and three days post partum, this did not affect litter size or body or brain weight of the offspring at birth. Injections of either drug or saline altered the rate of weight gain for the first month. The offspring of the amphetamine-treated mothers had lower levels of brain norepinephrine on the day of birth and higher levels of norepinephrine and dopamine than either control …

Morbidity, Growth And Development Of Prematurely-Born Twins In Early Childhood, Lynelle King

Loma Linda University Electronic Theses, Dissertations & Projects

This study was concerned with the problem of determining the effect of twinship on the prematurely-born twin's growth and physical and emotional morbidity during early childhood. The immediate purposes of the study were to compare prematurely-born twins with prematurely-born singletons regarding their incidence and types of physical and emotional morbidity, and their growth during early childhood. It was hypothesized that prematurely-born twins have slower growth and more physical and emotional morbidity than prematurely born singletons. The descriptive survey method was used. From children cared for at a selected premature clinic, nineteen twins were matched with nineteen singletons for: race, sex, …

A Study Of The Effect Of Varying Serum Phenylalanine Levels On Changes In Intelligence Quotient, Darlene Imai Manullang

Loma Linda University Electronic Theses, Dissertations & Projects

Data from thirty medical records of phenylketonuric children under treatment were investigated to determine at which serum phenylalanine level (0-3.9 mg. %, 4-7.9 mg %, 8-11.9 mg. %, greater than 12 mg. %) there would be the greatest increase in intelligence. The children involved in the study were divided into the following groups according to the age dietary treatment was initiated: 0 through 5 months, 6 through 11 months, 12 through 23 months, and over 2 years of age.

Among 6 patients who were placed on the diet during the first 5 months of life, it appears that the optimal …

Katharine Berry Richardson Certificate Of Death, Missouri State Board Of Health

Archives

Katharine B. Richardson, 121 Clinton Place, Kansas City MO, Sex Female, Color or Race White, Widow, Husband's Name James Richardson. Born Sept. 26, 1837 in Flat Rock, Ky. Died June 3, 1933 in the Nurses' home of Mercy Hospital. Occupation Founder of Mercy Hospital. Father's Name Stephen Berry, Mother's Maiden Name Harriet Benson. Buried June 6, 1933. Cause of Death Peritonitis (probably perforated gall bladder).