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Full-Text Articles in Medical Specialties

Improving Support Of Breastfeeding At A Baby-Friendly™ Designated Hospital In Albuquerque, New Mexico, Troy Hatfield, Connie Peceny, Julia M. Martinez, Priscilla Mendoza, Timothy J. Ozechowski, Rachel A. Sebastian, Emilie A. Sebesta, Mary M. Ramos Sep 2020

Improving Support Of Breastfeeding At A Baby-Friendly™ Designated Hospital In Albuquerque, New Mexico, Troy Hatfield, Connie Peceny, Julia M. Martinez, Priscilla Mendoza, Timothy J. Ozechowski, Rachel A. Sebastian, Emilie A. Sebesta, Mary M. Ramos

2020 Pediatric Research Forum Session

Purpose:

Breastfeeding has conclusively proven to be the healthiest feeding option for infants. Baby-Friendly™designated hospitals and birthing centers follow the Ten Steps to Successful Breastfeeding, which are considered to be the gold standard for supporting mothers who wish to breastfeed. However, even a Baby-Friendly™designated hospital may have room for improvement. The University of New Mexico Hospital (UNMH) is an urban hospital serving a predominantly Hispanic and Native American population, and the majority of pediatric patients are covered by Medicaid. Despite its Baby-Friendly™ designation, UNMH had low rates of physician documentation of discussing the health impacts of breastfeeding in the postpartum …


Erlotinib Therapy For Recurrent Respiratory Paillomatosis And Extralaryngeal Spread In Pediatrics, Shirley Abraham, John Kuttesch, Erica Bennett Sep 2020

Erlotinib Therapy For Recurrent Respiratory Paillomatosis And Extralaryngeal Spread In Pediatrics, Shirley Abraham, John Kuttesch, Erica Bennett

2020 Pediatric Research Forum Session

Background:

Recurrent respiratory papillomatosis (RRP) can be a potentially life-threatening condition and a treatment challenge. Local therapies are associated with significant scarring and detrimental effects on voice and respiratory status. EGFR inhibitors have been reported to be an effective adjunctive therapy in patients with RRP.

Objective:

To report our institutional experience with Erlotinib in two pediatric patients with severe RRP.

Method:

Retrospective chart review of 2 pediatric patients with severe RRP.

Results:

Patient 1 is a 19y/o female who was referred to us at the age of 11. Patient was diagnosed with respiratory papillomatosis at birth. Since age 1.5yrs, she …


Food And Housing Insecurity Screening Practices Among Unmh Pediatric Providers, Crystal Avila-Schroeder, Kyle Randolph, Lorena Galvan, Ana Duran, Maria Velazquez-Campbell Sep 2020

Food And Housing Insecurity Screening Practices Among Unmh Pediatric Providers, Crystal Avila-Schroeder, Kyle Randolph, Lorena Galvan, Ana Duran, Maria Velazquez-Campbell

2020 Pediatric Research Forum Session

Introduction:

The American Academy of Pediatrics recommends food insecurity (FI) screening at all pediatric visits. Despite an existing EMR screening tool, how our pediatric providers screen FI and housing insecurity (HI) is unknown. Our objective was to collect formative data on FI and HI screening practices of UNMH pediatric providers to allow for the design of a quality improvement (QI) project.

Methods:

We performed a baseline cross-sectional survey with UNMH pediatric residents and attendings in May 2020.

Results:

Fifty-two individuals completed the survey (40.4% attendings, 59.6% residents). In inpatient settings, 67.8% of residents and 33.3% of attendings screen FI occasionally …


Operability, Usefulness, And Task-Technology Fit Of An Mhealth App For Delivering Primary Health Care Services By Community Health Workers In Underserved Areas Of Pakistan And Afghanistan: Qualitative Study, Shehla Zaidi, Abdul Momin Kazi, Atif Riaz, Ammarah Ali, Rabia Najmi Taha, Rawshan Jabeen, Umerdad Khudadad, Saleem Sayani Sep 2020

Operability, Usefulness, And Task-Technology Fit Of An Mhealth App For Delivering Primary Health Care Services By Community Health Workers In Underserved Areas Of Pakistan And Afghanistan: Qualitative Study, Shehla Zaidi, Abdul Momin Kazi, Atif Riaz, Ammarah Ali, Rabia Najmi Taha, Rawshan Jabeen, Umerdad Khudadad, Saleem Sayani

Community Health Sciences

Background: The recent proliferation of digital health technology in low- and middle-income countries has made it possible for community health workers (CHWs) to use mobile health (mHealth) to perform tasks such as data collection and training. Although most studies focus on the prospect of digital apps to motivate and connect CHW, only a few have captured end-user experiences with mobile-based apps. We examined the experience of frontline health workers with a move towards digitalized real-time data to record maternal and childcare services in remote areas of Afghanistan and Pakistan.
Objective: Our study aimed to explore CHW perceptions on the operability …


Localized Intravascular Coagulopathy Of Venous Malformation Involving The Labia As A Mimic Of Child Sexual Abuse: A Case Report, Leslie Strickler, Lan Anh Van-Dinh, Christopher Torrez, Jessica Williams Sep 2020

Localized Intravascular Coagulopathy Of Venous Malformation Involving The Labia As A Mimic Of Child Sexual Abuse: A Case Report, Leslie Strickler, Lan Anh Van-Dinh, Christopher Torrez, Jessica Williams

2020 Pediatric Research Forum Session

Given location and relative rarity, ano-genital injuries in children often prompt concern for maltreatment. We present a case of localized intravascular coagulopathy as a complication of venous malformation, which mimicked abusive trauma leading to an evaluation for maltreatment. Comprehensive assessment identified the underlying medical cause. This case represents an example of the importance of objective assessment in unusual case presentations to ensure diagnostic accuracy, and appropriate direction of medical and child protection resources.


Lamotrigine Overdose Presenting As Shock And Pulmonary Edema, Savannah P. Ellenwood, John A. Mason, Nathaniel E. Link, Robert C. Hellinga, Natasha C. James, Anjali V. Subbaswamy Sep 2020

Lamotrigine Overdose Presenting As Shock And Pulmonary Edema, Savannah P. Ellenwood, John A. Mason, Nathaniel E. Link, Robert C. Hellinga, Natasha C. James, Anjali V. Subbaswamy

2020 Pediatric Research Forum Session

Abstract:

Lamotrigine is a broad-spectrum anti-epileptic drug with a good safety profile used to treat general and focal epilepsy. Toxicity is uncommon and usually mild, and symptoms usually include rash, headache, nausea, abdominal pain, somnolence, dizziness, and aggravated seizure activity. More severe adverse reactions are rare, but have been reported and include encephalopathy, hypotension, wide complex tachycardia, cardiac arrest, and death. Lamotrigine drug levels do not consistently correlate with either therapeutic effect or toxicity, though higher levels are thought to have a higher risk of toxicity. Also, the level is typically a send out test with a 1 to 3 …


Screening For And Diagnosing Malnutrition In Hospitalized Pediatric Patients, Samuel Thompson, Erin Lamers-Johnson, Kathryn Kelley, Lindsay Woodcock, Julie Long, Courtney Bliss, Jenica K. Abram, Alison Steiber, Elizabeth Yakes Jimenez Sep 2020

Screening For And Diagnosing Malnutrition In Hospitalized Pediatric Patients, Samuel Thompson, Erin Lamers-Johnson, Kathryn Kelley, Lindsay Woodcock, Julie Long, Courtney Bliss, Jenica K. Abram, Alison Steiber, Elizabeth Yakes Jimenez

2020 Pediatric Research Forum Session

Background:

Malnutrition is often underdiagnosed, and consequently undertreated, in hospitalized patients. A nationwide study is being conducted to validate indicators (the Malnutrition Clinical Characteristics [MCC]) to diagnose malnutrition in hospitalized patients.

Methods:

For the full study, sixty pediatric hospitals will collect patient medical history, patient STRONGKids malnutrition screening score, and nutrition intervention data. Six hundred pediatric patients will be randomly selected from the cohort to be assessed for the MCC and the Nutrition Focused Physical Exam (NFPE). Medical outcomes will be collected for all patients for a three-month period thereafter. Baseline data from a subset of sites that have started …


What Procedural Skills Are Practiced By Pediatricians In New Mexico?, Christal P. Chow, Anne Greene, Grace Mccauley Sep 2020

What Procedural Skills Are Practiced By Pediatricians In New Mexico?, Christal P. Chow, Anne Greene, Grace Mccauley

2020 Pediatric Research Forum Session

Background:

By the end of residency, pediatric residents are expected to be competent in 13 clinical procedures (bag mask ventilation, neonatal endotracheal intubation, umbilical catheter placement, lumbar puncture, simple laceration repair, incision and drainage of abscess, reduction of simple dislocation, temporary splinting of fractures, giving immunizations, bladder catheterization, peripheral intravenous catheter placement, removal of foreign body, and venipuncture). These procedural skills were initially identified as essential for practice in the general pediatric setting. However, procedures performed vary based on location, patient population, practice type, tertiary care support, etc. There are few studies available that evaluate the procedural skills used in …


Healers Of Tomorrow Zia Youth Project, Eliana Garcia, Emelia Pino, Anthony Fleg, Daisy Belmares-Ortega, Kevin Dileanis, Talyia Torres Sep 2020

Healers Of Tomorrow Zia Youth Project, Eliana Garcia, Emelia Pino, Anthony Fleg, Daisy Belmares-Ortega, Kevin Dileanis, Talyia Torres

2020 Pediatric Research Forum Session

This youth advocacy effort follows the story of high school student Emelia Pino and Healers of Tomorrow leaders as they work to address health inequities in her home of Zia Pueblo, one of the communities hit hardest in New Mexico by the pandemic.

While taking part in The Healers of Tomorrow Program, a mentorship program for underrepresented high school students, Emelia conveyed the hardships her people were experiencing to program leaders. This kickstarted allied relief efforts in response to rising COVID-19 cases. Emilia and her mentors worked alongside several organizations, including NHI and Protect New Mexico, to gather PPE and …


Semmes Weinstein Sensory Testing At The Fingertip: Should 2.83 Be The Norm?, Emily Moore, Ogochukwu Nwagbologu, Samantha Specht, Rebecca A. Dutton, Patricia Siegel Sep 2020

Semmes Weinstein Sensory Testing At The Fingertip: Should 2.83 Be The Norm?, Emily Moore, Ogochukwu Nwagbologu, Samantha Specht, Rebecca A. Dutton, Patricia Siegel

2020 Pediatric Research Forum Session

Category: In-Progress Research

The Semmes-Weinstein monofilament test (SWM) is an objective test of sensation that is commonly used to identify sensory impairments in the hand.

Objective:

To determine if male and female subjects aged 25 and older with no history of sensory symptoms or known neurologic conditions would feel the 2.83 (normal) Semmes Weinstein monofilament, and if a relationship between the detected monofilament and grip strength exists.

Outcome Measures:

Ability to detect the 2.83 (normal) monofilament at the fingertip. Participants were dichotomized into two groups: the 2.83 “normal” (ability to detect the 2.83 monofilament in three or …


Supporting Coordination Of Children With Asd Using Neurological Music Therapy: A Pilot Randomized Control Trial Comparing An Elastic Touch-Display With Tambourines, Franceli L. Cibrian, Melisa Madrigal, Marina Avelais, Monica Tentori Sep 2020

Supporting Coordination Of Children With Asd Using Neurological Music Therapy: A Pilot Randomized Control Trial Comparing An Elastic Touch-Display With Tambourines, Franceli L. Cibrian, Melisa Madrigal, Marina Avelais, Monica Tentori

Engineering Faculty Articles and Research

Aim

To evaluate the efficacy of Neurologic Music Therapy (NMT) using a traditional and a technological intervention (elastic touch-display) in improving the coordination of children with Autism Spectrum Disorder (ASD), as a primary outcome, and the timing and strength control of their movements as secondary outcomes.

Methods

Twenty-two children with ASD completed 8 NMT sessions, as a part of a 2-month intervention. Participants were randomly assigned to either use an elastic touch-display (experimental group) or tambourines (control group). We conducted pre- and post- assessment evaluations, including the Developmental Coordination Disorder Questionnaire (DCDQ) and motor assessments related to the control of …


Parent Responses To Pediatric Pain: The Differential Effects Of Ethnicity On Opioid Consumption, Candice D. Donaldson, Brooke N. Jenkins, Michelle A. Fortier, Michael T. Phan, Daniel M. Tomaszewski, Sun Yang, Zeev N. Kain Sep 2020

Parent Responses To Pediatric Pain: The Differential Effects Of Ethnicity On Opioid Consumption, Candice D. Donaldson, Brooke N. Jenkins, Michelle A. Fortier, Michael T. Phan, Daniel M. Tomaszewski, Sun Yang, Zeev N. Kain

Psychology Faculty Articles and Research

Objective

Within the context of the United States opioid epidemic, some parents often fear the use of opioids to help manage their children's postoperative pain. As a possible consequence, parents often do not dispense optimal analgesic medications to their children after surgery, putting their children at risk of suffering from postsurgical pain. The objective of this research was to assess ethnicity as a predictor of both pain and opioid consumption, and to examine how Hispanic/Latinx and Non-Hispanic White parents alter their child's opioid consumption in response to significant postsurgical pain.

Methods

Participants were 254 children undergoing outpatient tonsillectomy and/or adenoidectomy …


Esophageal, Gastric, And Duodenal Histologic Findings In Patients With Feeding Difficulties., Jensen Edwards, Craig A. Friesen, Amy Issa, Sarah T. Edwards Sep 2020

Esophageal, Gastric, And Duodenal Histologic Findings In Patients With Feeding Difficulties., Jensen Edwards, Craig A. Friesen, Amy Issa, Sarah T. Edwards

Manuscripts, Articles, Book Chapters and Other Papers

Currently, there are inconsistencies in the recommendations of when to obtain an esophagogastroduodenoscopy (EGD) in children with feeding difficulties. The aim of our study was to identify EGD findings in patients presenting to a large, outpatient feeding program. Additionally, we investigated the presence of any relationship between abnormal pathology seen on biopsies (inflammation) and symptoms of feeding intolerance such as vomiting, gagging, retching, or abdominal pain. Retrospective analysis of electronic medical records (EMRs) was conducted for all new patients aged 0-17 years presenting to the Multidisciplinary Feeding Clinic. Three hundred and thirty patients (50.2%) had an EGD with complete biopsies. …


Beyond Clinical Food Prescriptions And Mobile Markets: Parent Views On The Role Of A Healthcare Institution In Increasing Healthy Eating In Food Insecure Families., Emily Dewit, Emily Meissen-Sebelius, Robin P. Shook, Kimberly Pina, Evelyn Donis De Miranda, Michelle J. Summar, Emily A. Hurley Sep 2020

Beyond Clinical Food Prescriptions And Mobile Markets: Parent Views On The Role Of A Healthcare Institution In Increasing Healthy Eating In Food Insecure Families., Emily Dewit, Emily Meissen-Sebelius, Robin P. Shook, Kimberly Pina, Evelyn Donis De Miranda, Michelle J. Summar, Emily A. Hurley

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Children in food-insecure families face increased barriers to meeting recommendations for fruit and vegetable consumption. Hospitals and pediatric healthcare institutions have attempted to alleviate food-insecurity through various internal programs like food prescriptions, yet little evidence for these programs exist. Consistent with a patient-centered perspective, we sought to develop a comprehensive understanding of barriers to fruit and vegetable consumption and a parent-driven agenda for healthcare system action.

METHODS: We conducted six qualitative focus group discussions (four in English, two in Spanish) with 29 parents and caregivers of patients who had screened positive for food-insecurity during visits to a large pediatric …


Perinatal Palliative Care Birth Planning As Advance Care Planning., Donnamaria E. Cortezzo, Kelstan Ellis, Amy Schlegel Sep 2020

Perinatal Palliative Care Birth Planning As Advance Care Planning., Donnamaria E. Cortezzo, Kelstan Ellis, Amy Schlegel

Manuscripts, Articles, Book Chapters and Other Papers

Purpose of Review: A significant number of pregnancies are complicated by a fetus with a life-limiting diagnosis. As diagnoses are made earlier in the pregnancy, families experience anticipatory grief and are faced with navigating goals of care for a baby that has yet to be born. With the support of the care team, families can begin to grieve, plan, and make meaningful memories during the duration of the pregnancy, the birth of their baby, and life of the child. Creating a palliative care birth plan, which expands beyond the traditional concept for delivery planning to include prenatal, perinatal, and neonatal …


Prosthetic Temporomandibular Joint Reconstruction In A Cohort Of Adolescent Females With Juvenile Idiopathic Arthritis., Michael Lypka, Karina Shah, Jordan T. Jones Sep 2020

Prosthetic Temporomandibular Joint Reconstruction In A Cohort Of Adolescent Females With Juvenile Idiopathic Arthritis., Michael Lypka, Karina Shah, Jordan T. Jones

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Temporomandibular joint (TMJ) arthritis and involvement is commonly seen in Juvenile Idiopathic Arthritis (JIA). Therapy includes conservative measures, but also includes intraarticular corticosteroid injections (IASI) and systemic immunosuppressive therapy. Despite aggressive medical therapy, some patients develop arthritic changes and frank TMJ ankylosis that can result in persistent pain and limitation in range of motion (ROM). A surgical option is prosthetic TMJ replacement with concurrent correction of dentofacial deformities, which can be performed simultaneously. The objective of this study was to evaluate the outcomes of prosthetic TMJ replacement in a cohort of adolescent females with JIA and severe TMJ involvement. …


Non-Steroidal Or Opioid Analgesia Use For Children With Musculoskeletal Injuries (The No Ouch Study): Statistical Analysis Plan., Anna Heath, Maryna Yaskina, Gareth Hopkin, Terry P Klassen, Christopher Mccabe, Martin Offringa, Petros Pechlivanoglou, Juan David Rios, Naveen Poonai, Samina Ali Sep 2020

Non-Steroidal Or Opioid Analgesia Use For Children With Musculoskeletal Injuries (The No Ouch Study): Statistical Analysis Plan., Anna Heath, Maryna Yaskina, Gareth Hopkin, Terry P Klassen, Christopher Mccabe, Martin Offringa, Petros Pechlivanoglou, Juan David Rios, Naveen Poonai, Samina Ali

Paediatrics Publications

BACKGROUND: Pediatric musculoskeletal injuries cause moderate to severe pain, which should ideally be addressed upon arrival to the emergency department (ED). Despite extensive research in ED-based pediatric pain treatment, recent studies confirm that pain management in this setting remains suboptimal. The No OUCH study consist of two complementary, randomized, placebo-controlled trials that will run simultaneously for patients presenting to the ED with an acute limb injury and a self-reported pain score of at least 5/10, measured via a verbal numerical rating scale (vNRS). Caregiver/parent choice will determine whether patients are randomized to the two-arm or three-arm trial. In the two-arm …


Current Challenges Of Digital Health Interventions In Pakistan: Mixed Methods Analysis, Abdul Momin Kazi, Saad Ahmed Qazi, Nazia Ahsan, Sadori Khawaja, Fareeha Sameen, Muhammad Ayub Khan Mughal, Zabin Wajidali, Hussain Kalimuddin, Yasir Rauf, Fatima Mahmood Sep 2020

Current Challenges Of Digital Health Interventions In Pakistan: Mixed Methods Analysis, Abdul Momin Kazi, Saad Ahmed Qazi, Nazia Ahsan, Sadori Khawaja, Fareeha Sameen, Muhammad Ayub Khan Mughal, Zabin Wajidali, Hussain Kalimuddin, Yasir Rauf, Fatima Mahmood

Department of Paediatrics and Child Health

Background: Digital health is well-positioned in low and middle-income countries (LMICs) to revolutionize health care due, in part, to increasing mobile phone access and internet connectivity. This paper evaluates the underlying factors that can potentially facilitate or hinder the progress of digital health in Pakistan.
Objective: The objective of this study is to identify the current digital health projects and studies being carried out in Pakistan, as well as the key stakeholders involved in these initiatives. We aim to follow a mixed-methods strategy and to evaluate these projects and studies through a strengths, weaknesses, opportunities, and threats (SWOT) analysis to …


Examining Blood Culture Contamination Rates Using Maxzero Needleless Connectors, Leslie Bagley, Melissa Tramp Sep 2020

Examining Blood Culture Contamination Rates Using Maxzero Needleless Connectors, Leslie Bagley, Melissa Tramp

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No abstract provided.


Moral Distress To Moral Courage, A Pathway To Success For Resident Nurses, Melinda Furrer Sep 2020

Moral Distress To Moral Courage, A Pathway To Success For Resident Nurses, Melinda Furrer

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No abstract provided.


Achieving Increased Quality Outcomes For Pediatric Oncology Through Psychosocial Screening: An Integrative Research Review, Kaitlyn Williams Sep 2020

Achieving Increased Quality Outcomes For Pediatric Oncology Through Psychosocial Screening: An Integrative Research Review, Kaitlyn Williams

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No abstract provided.


Quantification And Characterization Of Granulocyte Macrophage Colony-Stimulating Factor Activated Human Peripheral Blood Mononuclear Cells By Fluorine-19 Cellular Mri In An Immunocompromised Mouse Model, C Fink, M Smith, O C Sehl, J M Gaudet, T C Meagher, N A Sheikh, Jimmy Dikeakos, Michael Rieder, P J Foster, G A Dekaban Sep 2020

Quantification And Characterization Of Granulocyte Macrophage Colony-Stimulating Factor Activated Human Peripheral Blood Mononuclear Cells By Fluorine-19 Cellular Mri In An Immunocompromised Mouse Model, C Fink, M Smith, O C Sehl, J M Gaudet, T C Meagher, N A Sheikh, Jimmy Dikeakos, Michael Rieder, P J Foster, G A Dekaban

Paediatrics Publications

PURPOSE: The purpose of this study was to test fluorine-19 (19F) cellular magnetic resonance (MRI) as a non-invasive imaging modality to track therapeutic cell migration as a surrogate marker of immunotherapeutic effectiveness.

MATERIALS AND METHODS: Human peripheral blood mononuclear cell- (PBMC)-derived antigen presenting cell (APC) were labeled with a 19F-perfluorocarbon (PFC) and/or activated with granulocyte macrophage colony-stimulating factor (GM-CSF). Viability, phenotype and cell lineage characterization preceded 19F cellular MRI of PFC

RESULTS: A high proportion of PBMC incorporated PFC without affecting viability, phenotype or cell lineage composition. PFC

CONCLUSION: 19F cellular MRI is a non-invasive imaging technique capable of detecting …


Priority Outcomes In Critically Ill Children: A Patient And Parent Perspective, Nora Fayed, Saoirse Cameron, Douglas Fraser Md, Phd, Frcpc, Jill I Cameron, Samah Al-Harbi, Racquel Simpson, Maha Wakim, Lily Chiu, Karen Choong Sep 2020

Priority Outcomes In Critically Ill Children: A Patient And Parent Perspective, Nora Fayed, Saoirse Cameron, Douglas Fraser Md, Phd, Frcpc, Jill I Cameron, Samah Al-Harbi, Racquel Simpson, Maha Wakim, Lily Chiu, Karen Choong

Paediatrics Publications

BACKGROUND: Outcomes in pediatric critical care research are typically selected by the researcher.

OBJECTIVES: (1) To identify outcomes prioritized by patients and their families following a critical illness and (2) to determine the overlap between patient-centered and researcher-selected study outcomes.

METHODS: An exploratory descriptive qualitative study nested within a longitudinal cohort study conducted in 2 pediatric intensive care units (PICUs). Participants were purposively sampled from the primary cohort to ensure adequate demographic representation. Qualitative descriptive approaches based on naturalistic observation were used to collect data and analyze results. Data were coded by using the International Classification of Functioning, Disability, and …


New Aspects Of The Epigenetics Of Pancreatic Carcinogenesis., Murat Toruner, Martin E. Fernandez-Zapico, Christopher Pin Sep 2020

New Aspects Of The Epigenetics Of Pancreatic Carcinogenesis., Murat Toruner, Martin E. Fernandez-Zapico, Christopher Pin

Paediatrics Publications

Pancreatic cancer remains among the deadliest forms of cancer with a 5 year survival rate less than 10%. With increasing numbers being observed, there is an urgent need to elucidate the pathogenesis of pancreatic cancer. While both contribute to disease progression, neither genetic nor environmental factors completely explain susceptibility or pathogenesis. Defining the links between genetic and environmental events represents an opportunity to understand the pathogenesis of pancreatic cancer. Epigenetics, the study of mitotically heritable changes in genome function without a change in nucleotide sequence, is an emerging field of research in pancreatic cancer. The main epigenetic mechanisms include DNA …


Cerebellar Mutism Syndrome After Surgical Resection Of Posterior Fossa Neoplastic Lesions, Saqib Kamran Bakhshi, Rida Mitha, Naureen Mushtaq, Muhammad Shahzad Shamim Sep 2020

Cerebellar Mutism Syndrome After Surgical Resection Of Posterior Fossa Neoplastic Lesions, Saqib Kamran Bakhshi, Rida Mitha, Naureen Mushtaq, Muhammad Shahzad Shamim

Section of Neurosurgery

Cerebellar Mutism Syndrome (CMS) is a well-described clinical entity that complicates surgeries for posterior fossa tumours; more so in children than adults. This review focuses on the current understanding of CMS, its incidence and risk factors. Incidence showed a variable range in retrospective studies due to variety of definitions. Risk factors can be classified as either modifiable including surgical technique, or non-modifiable which include tumour related factors. A positive correlation has been associated between tumour pathology, brain stem invasion and size of tumour at time of presentation with development of CMS.


Correction To: Medical Neglect As A Contributor To Poorly Controlled Asthma In Childhood., Barbara L Knox, Francois M Luyet, Debra Esernio-Jenssen Sep 2020

Correction To: Medical Neglect As A Contributor To Poorly Controlled Asthma In Childhood., Barbara L Knox, Francois M Luyet, Debra Esernio-Jenssen

Articles, Abstracts, and Reports

[This corrects the article DOI: 10.1007/s40653-019-00290-0.].


Frequency And Outcome Of Meconium Aspiration Syndrome In Babies Born With Meconium-Stained Liquor At Secondary Care Hospital In Pakistan: A Case Series Study, Abdul Moeed, Heeramani Lohana, Sarwat Urooj, Sheraz Ahmed, Khalil Ahmed, Khadija N Humayun Sep 2020

Frequency And Outcome Of Meconium Aspiration Syndrome In Babies Born With Meconium-Stained Liquor At Secondary Care Hospital In Pakistan: A Case Series Study, Abdul Moeed, Heeramani Lohana, Sarwat Urooj, Sheraz Ahmed, Khalil Ahmed, Khadija N Humayun

Department of Paediatrics and Child Health

Background: Meconium aspiration syndrome (MAS) in the newborn is characterized by hypoxia, hypercapnia, and acidosis. MAS is a leading cause of morbidity and mortality in neonates. The primary objective of this study was to estimate the frequency of meconium aspiration syndrome (MAP) in babies born with meconium-stained liquor. The secondary outcome was to estimate the meconium aspiration syndrome; in terms of hospital stay, complications, and mortality.
Methods: The study was done at Aga Khan Maternal and Child Care Centre, Hyderabad, Pakistan. Study design was case series and the duration of the study was of 6 months. All patients who fulfilled …


Determinants Of Health Care Seeking Behaviors In Puerperal Sepsis In Rural Sindh, Pakistan: A Qualitative Study, Shabina Ariff, Fatima Mir, Farhana Tabassum, Farrukh Raza, Atif Habib, Ali Turab, Amnesty Lefevre, Linda A. Bartlett, Sajid Bashir Soofi, Zulfiqar Ahmed Bhutta Sep 2020

Determinants Of Health Care Seeking Behaviors In Puerperal Sepsis In Rural Sindh, Pakistan: A Qualitative Study, Shabina Ariff, Fatima Mir, Farhana Tabassum, Farrukh Raza, Atif Habib, Ali Turab, Amnesty Lefevre, Linda A. Bartlett, Sajid Bashir Soofi, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Background: Puerperal sepsis (PS) is one of the major causes of maternal death, contributing to 26,000 deaths per year in developing countries. Early recognition and treatment are essential to managing PS, but numerous social, cultural and technical barriers prevent or delay access to care and necessary medical attention. Through this qualitative study, we identified barriers to care seeking for puerperal sepsis among recently delivered women in Matiari, Pakistan.
Methods: We conducted 20 in-depth interviews among recently delivered women with and without sepsis and their family members in September 2012. Key informant interviews were conducted with 14 healthcare providers and traditional …


Cinacalcet Studies In Pediatric Subjects With Secondary Hyperparathyroidism Receiving Dialysis., Bradley A. Warady, Eric Ng, Laura Bloss, May Mo, Franz Schaefer, Justine Bacchetta Sep 2020

Cinacalcet Studies In Pediatric Subjects With Secondary Hyperparathyroidism Receiving Dialysis., Bradley A. Warady, Eric Ng, Laura Bloss, May Mo, Franz Schaefer, Justine Bacchetta

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Secondary hyperparathyroidism (sHPT), a complication of chronic kidney disease (CKD) characterized by persistently elevated parathyroid hormone (PTH), alterations in calcium-phosphorus homeostasis, and vitamin D metabolism, affects 50% of children receiving dialysis. A significant proportion of these children develop CKD-mineral and bone disorder (CKD-MBD), associated with an increased risk of fractures and vascular calcification. The standard of care for sHPT in children includes vitamin D sterols, calcium supplementation, and phosphate binders. Several agents are approved for sHPT treatment in adults undergoing dialysis, including vitamin D analogs and calcimimetics, with limited information on their safety and efficacy in children. The calcimimetic …


Investigation Of A Peculiar Case Of Childhood Lymphadenopathy, Chade Aribo, Alonso Al, Allison Woodall, Tommy Y. Kim Aug 2020

Investigation Of A Peculiar Case Of Childhood Lymphadenopathy, Chade Aribo, Alonso Al, Allison Woodall, Tommy Y. Kim

HCA Healthcare Journal of Medicine

Introduction: Lymphadenopathy is a common physical finding often associated with an infectious etiology. We present a case of a patient with generalized cervical and supraclavicular lymphadenopathy diagnosed with a rare malignancy. Health care providers should be aware of some uncommon historical or physical examination findings that warrant further investigation.

Clinical Findings: A 16-year-old female presented to the emergency department with 3 days of a fever, congestion and sore throat with swelling around the jaw. Her physical examination findings included bilateral mandibular swelling and generalized cervical lymphadenopathy with palpable supraclavicular lymph nodes.

Outcomes: Complete blood count showed pancytopenia with a white …