Medical Specialties Commons^™

Toxicity Following Antiemetic Ingestions Reported To The Toxicology Investigators Consortium Core Registry, Jacob Fisher, Spencer Greene, Sharan Campleman

Gulf Coast Division GME Research Day 2026

No abstract provided.

Nicotine Self-Administration And The Impacts On Medial Habenula And Interpeduncular Nucleus Neurophysiology, Nathan Alexander Olszewski

Theses, Dissertations and Capstones

Nicotine use is a tremendous public health issue in the United States, with over 23 million people being dependent on the substance. Low cessation rates associated with nicotine use are largely attributed to the withdrawal and craving symptoms that occur after abstinence of use from nicotine. The medial habenula (MHb) and interpeduncular nucleus (IPN) are two brain regions heavily associated and linked with nicotine withdrawal. Here, I sought to understand how these brain regions are altered in their physiology during nicotine intake. Utilizing E-Vape self-administration, mice were first taught to selfadminister nicotine of various, clinically relevant, dosages which correlate to …

Vestibular Migraine And Ssri Withdrawal, Grace Fairchild, Sarah Redding, Ashley Flagge

V&B Posters

No abstract provided.

Vestibular Migraine And Ssri Withdrawal: A Case Presentation, Grace Fairchild, Sarah Redding, Ashley Flagge

V&B Presentations

No abstract provided.

Vitamin D Status During Pregnancy Modulates The Effect Of Pre-Pregnancy Obesity On Gestational Diabetes Mellitus Risk: A Birth Cohort Study, Ali H. Ziyab, Abdullah Al-Taiar, Reem Al-Sabah, Majeda S. Hammoud, Saeed Akhtar

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Objective:

To determine whether gestational vitamin D status modulates the effect of pre-pregnancy obesity on gestational diabetes mellitus (GDM) risk while stratifying by maternal age.

Design:

Birth cohort.

Setting:

A major maternity hospital in Kuwait.

Participants:

Pregnant women in their second/third trimester of gestation were enrolled. Pre-pregnancy body mass index (BMI, kg/m²) was categorized as under/normal weight (< 25.0), overweight (25.0 to < 30.0), and obesity (≥30.0). Gestational 25-hydroxyvitamin D concentrations were categorized as deficiency (< 50 nmol/L) or insufficiency/sufficiency (≥50 nmol/L). GDM status was ascertained according to international guidelines. Adjusted odds ratios (aOR) and 95% confidence intervals (CI) were estimated using logistic regression.

Results:

Data from 957 pregnant women were analyzed, with GDM affecting 166 (17.4%) pregnancies. Pre-pregnancy obesity and gestational vitamin D deficiency was ascertained in 275 (28.7%) and 533 (55.7%) pregnant women, respectively. The association between pre-pregnancy obesity and GDM risk differed according …

Medical Toxicology: A Safety Net For Snakebite Victims, Braden Capt, George Warpinski, Sharan Campleman, Anne-Michelle Ruha, Spencer Greene

Gulf Coast Division GME Research Day 2026

No abstract provided.

Apoe4 Drives Maladaptive Heterogeneity And Immunometabolic Responses Of Astrocytes, Danielle S. Goulding, Holden C. Williams, Amy A. Gorman, Nicholas A. Devanney, Douglas A. Harrison, Adeline E. Walsh, Tony Tuck, Diana J. Zajac, Shannon L. Macauley, Steven Estus, Julia Tcw, Lance A. Johnson, Josh M. Morganti

Sanders-Brown Center on Aging Faculty Publications

Apolipoprotein E4 (APOE4) is the strongest risk allele associated with the development of late onset Alzheimer’s disease (AD). Across the CNS, astrocytes are the predominant expressor of APOE while also being critical mediators of neuroinflammation and cerebral metabolism. APOE4 has been consistently linked with dysfunctional inflammation and metabolic processes, yet insights into the molecular constituents driving these responses remain unclear. Utilizing complementary approaches across humanized APOE mice and isogenic human iPSC astrocytes, we demonstrate that ApoE4 alters the astrocyte immunometabolic response to pro-inflammatory stimuli. Our findings show that ApoE4-expressing astrocytes acquire distinct transcriptional repertoires at single-cell and spatially-resolved domains, which …

Stim1-Dependent Treg Dysfunction Promotes Cardiometabolic Hfpef: Insights From Patients And Animal Studies, Balaji Srinivas, Alluri Kiran, Hongmei Peng, Jiang Xu, Paula Fortuno, Jennifer May, Ismail El Moudden, Nour-Eddine Rhaleb, John M. Herre, Raymond L. Benza, Khalid Matrougui

Department of Biomedical and Translational Sciences Faculty Publications

Background

Heart failure with preserved ejection fraction (HFpEF) arises from chronic cardiometabolic and vascular stress and is increasingly recognized as an inflammatory syndrome with immune dysregulation. Regulatory T cells (Tregs) are critical modulators of cardiovascular inflammation, yet the mechanisms driving Treg dysfunction in HFpEF remain poorly defined. stromal interaction molecule 1 (STIM1)-dependent calcium signaling is a key stress-responsive pathway in immune cells; however, its role in Treg maladaptation during HFpEF remains unknown.

Methods

Circulating Tregs from patients with and without HFpEF were analyzed for abundance, STIM1 expression, and stress-associated signaling pathways. To establish causality, mice with Treg-specific deletion of STIM1 …

Animal Models Of Aortic Aneurysm And Dissection: A Comparative Guide For Mechanism, Therapeutic Testing, And Translational Readouts, Shayan Mohammadmoradi, Sidney W. Whiteheart

Saha Cardiovascular Research Center Faculty Publications

Aortic aneurysms and dissections are devastating vascular diseases with high mortality, yet no pharmacological therapy has proven effective in halting growth or preventing rupture. Surgical and endovascular repair remain the only treatment options for advanced disease. Animal models have been indispensable in defining mechanisms and testing candidate therapies, but the diversity of protocols, strain-dependent variability, and heterogeneous endpoints complicate interpretation and translation. This review provides an update focused on how to match models to specific research questions. We critically compare commonly used abdominal aortic aneurysm (AAA) models (angiotensin II ± hyperlipidemia, elastase, calcium chloride, β-aminopropionitrile BAPN hybrids, and mineralocorticoid agonist/fludrocortisone …

Differences In Biologic Clinical Trials For Chronic Rhinosinusitis With Nasal Polyps—Are We Comparing Apples With Oranges?, Marjolein Cornet, Peter W. Hellings, Martin Desrosiers, Martin Wagenmann, Richard Follows, Laura Walrave, Luz Adriana Jimenez, Lee Tombs, Dawn Edwards, Peter Howarth, Joseph K. Han

Department of Otolaryngology (ENT) Faculty Publications

In recent years, several biologics targeting Type 2 inflammation have been developed for treating chronic rhinosinusitis with nasal polyps (CRSwNP). These have been studied in registrational randomized controlled trials (RCTs), which vary in their patient populations, trial design, endpoints, geography, timing, or data-handling processes. While (in)direct treatment comparisons and meta-analyses have been carried out to compare efficacy results from RCTs, often these fail to properly account for these between-study differences. Here, we summarize the key between-study differences that can influence trial outcomes and highlight the resulting challenges faced when comparing outcomes from different Phase III RCTs of biologics in CRSwNP.

Longitudinal Changes In Plasma Biomarkers Of Immune Activation, Neuronal Inflammation And Injury In Persons With Hiv Initiating Art, Merle Henderson, Peter Dutey-Magni, Carolina Herrera, Wolfgang Stöhr, Alejandro Arenas-Pinto, Owen Swann, Amanda Heslegrave, Henrik Zetterberg, John Tregoning, Sarah Fidler, François Raffi, Andrea Calcagno, Ab Babiker, Alan Winston

CONRAD Publications

Background

Data on changes in biomarkers of brain health, and their associations with cognitive function in adults commencing either dual- or triple-antiretroviral therapy (ART) are sparse.

Methods

Plasma biomarkers (neurofilament light [NfL], glial fibrillary acidic protein [GFAP], sCD14, CXCL10, neopterin and IL-6) were measured at baseline and after 96 weeks on ART in individuals randomized to darunavir/ritonavir and either tenofovir-DF/emtricitabine (triple-ART, n = 119) or raltegravir (dual-ART, n = 119) in NEAT-001/ANRS143. Regression models examined associations of baseline and week-96 biomarker concentrations with HIV clinical parameters, composite cognitive test scores (Standardized neuropsychological test [NPZ], 7-domains) and treatment arm.

Results

In …

The Impact Of Gastric Sleeve And Roux-En-Y Gastric Bypass On Chief Cell Function And Protein Digestion In Obese Patients, Garikoitz Mikel Gainza

Honors Undergraduate Theses

Obesity has become one of the largest global health concerns of the 21^st century, correlating with numerous associated diseases. To help address the growing prevalence and burden of obesity, sleeve gastrectomy and Roux-en-Y gastric bypass have become two commonly performed surgical procedures done to promote weight loss by altering the anatomical structure of the stomach and surrounding organs of the gastrointestinal system. Although the benefits of improved metabolism linked to these surgical procedures are well studied, their impact on the physiology of gastric cells, and more specifically chief cells as they relate to protein digestion post-surgery, is yet to …

An Anti-Adhesive Compound Modulating The Production Of Staphylococcus Aureus Cell Wall-Anchored Proteins, Allison C. Leonard, Ruina Bao, Cindy Menjivar, Megan J. Myers, Telmo O. Paiva, Zhiyong Zheng, Kirsten A. Berry, Kenneth W. Bayles, Ronald S. Flannagan, Yves F. Dufrêne, Jeffrey L. Bose, David E. Heinrichs, Georgina Cox

Journal Articles: Pathology and Microbiology

As one of the leading global causes of death associated with antimicrobial resistance, Staphylococcus aureus frequently colonizes the human nasal cavity and adheres to keratinized skin, establishing reservoirs that drive subsequent infections and emphasize the need for new decolonization strategies. Using a high-throughput, whole-cell screening platform, here we identify geranylgeranoic acid (GGA), a naturally occurring polyunsaturated, branched-chain fatty acid, as having dual activity against methicillin-resistant S. aureus (MRSA). At elevated concentrations, GGA exhibits microbicidal effects, whereas at sub‑microbicidal doses, it effectively inhibits MRSA adhesion to keratin, fibronectin, fibrinogen, and immunoglobulins. GGA possesses anti-adhesive activity against a panel of multidrug-resistant S. …

Dual Orexin Receptor Antagonism With Lemborexant Enhances Microglial Clearance Of Β-Amyloid In Mice, Ashish Sharma, Emiko Segawa, Xiaoying Chen, Sohui Park, Shoutang Wang, Riley E. Irmen, Nicholas J. Constantino, Chanung Wang, Michael F. Kanan, Marco Colonna, Shannon L. Macauley, Jocelyn Y. Cheng, Ken Hatanaka, Margaret Moline, Erik S. Musiek

Sanders-Brown Center on Aging Faculty Publications

Background: Sleep disturbances elevate brain amyloid-beta (Aβ) levels and represent a modifiable risk factor for Alzheimer’s disease (AD). The orexin/hypocretin system regulates sleep–wake behavior and has emerged as a therapeutic target in AD; however, the effects of FDA-approved dual orexin receptor antagonists (DORAs) on amyloid pathology remain unclear. We compared lemborexant, an FDA-approved DORA, to doxepin, an antihistaminergic sleep medication, on amyloid pathology and microglial responses in PSAPP mice.

Methods: PSAPP mice received lemborexant (10 or 30 mg/kg/day), doxepin (35 mg/kg/day), or vehicle for 6 weeks beginning prior to plaque onset or 4 weeks after established pathology. Sleep was assessed …

Effectiveness Of Interferential Stimulation And Anorectal Neuromuscular Electrical Stimulation On Secondary Encopresis In Children: A Comparative Randomized Controlled Clinical Trial, Seham M. Abd El-Moghny, Mohamed I. Elsepaee, Abdelaty Alghonimy, Rabab S. Mohamed

Journal of Medicine in Scientific Research

Background Encopresis, fecal soiling is often secondary to functional constipation and retention. It is significantly impact a child's psychological health as it can result in feelings of shame, social isolation, and low self-esteem and negatively affect their quality of life and their families. Objective To evaluate and compare the efficacy and safety of interferential stimulation (IF) applied on sigmoid colon and anorectal neuromuscular electrical stimulation (NMES), in combination with behavioral therapy and pelvic floor muscle training (PFMT), in improving continence outcomes in children with secondary encopresis refractory to laxatives. Methods In this comparative randomized controlled clinical trial, 30 children (5–10 …

Prospective Validation And Comparison Of Laboratory Risk Indicator For Necrotizing Fasciitis (Lrinec) And Site Other Than Lower Limb, Immunosuppression, Age, Renal Impairment, And Inflammatory Markers (Siari) Scoring Systems For Necrotizing Fasciitis In Critically Ill Patients., Talal Ibrahim Mostafa Hagag, Shimaa Mohamed Kalama

Journal of Medicine in Scientific Research

Background Necrotizing soft tissue infections (NSTIs) are rapidly progressive infections that are dangerous to life, with high morbidity and mortality. Prompt surgical and medical management is necessary and stands mostly on precise identification as well as risk stratification. In order to enhance diagnostic as well as prognostic accuracy, prognostic scoring systems like the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) as well as the most recent Site, Immunosuppression, Age, Renal impairment, and inflammatory markers (SIARI) score, were introduced. Methods A prospective observational cohort study was carried out during June-August 2024 in Shebin Elkom Teaching Hospital among 60 patients who had …

Thyroid Function Abnormalities Among Reproductive-Aged Women With Menstrual Irregularities In A Tertiary Teaching Hospital, Ahmed Alsayed Kassab, Amira Yones Mohamed

Journal of Medicine in Scientific Research

Background and Objective:Menstrual irregularities are a common gynecological complaint, often linked to thyroid dysfunction, which disrupts the hypothalamic–pituitary–ovarian axis. This study sought to assess prevalence of thyroid dysfunction among reproductive-aged women with menstrual irregularities and to evaluate the specific clinical and hormonal correlations between different menstrual patterns and Thyroid Status. Methods:A cross-sectional study was conducted on 120 women presenting with menstrual irregularities. Participants were classified as Euthyroid, Subclinical Hypothyroid, Overt Hypothyroid, or Hyperthyroid. Descriptive statistics summarized baseline data (e.g., mean Age = 29.63 plus or minus 7.97 years). The association between Menstrual Irregularity Type and Thyroid Status was assessed using …

What Is The Association Between Iron Deficiency Anemia And The Frequency Or Severity Of Febrile Seizures In Children Under The Age Of 5?, Rehab Fawzy Abdel Mohsen Soliman, Samar Mahmoud Ahmed, Yasmen Ahmed Said, Shaimaa Mohamed Hassan, Dalia Hassanin Hussin, Dina Gaber Soliman, Zeinab Abdalla Ali, Eman Farouk Osman

Journal of Medicine in Scientific Research

Background and Aim Febrile seizures (FS) are a common type of convulsion in young children and are frequently associated with fever in the absence of a central nervous system infection. This study aims to investigate the relationship between iron deficiency and febrile seizures, focusing on their occurrence, severity, and recurrence in children aged 6 months to 5 years. Methodology This study employed a case-control design and was conducted at El Sahel Teaching Hospital in Cairo, Egypt, over 12 months. The study sample consisted of 160 children, 80 of whom had febrile seizures and another 80 who were age- and sex-matched …

A Comparison Of Haemodialysis And Renal Transplantation On Male Sexual Function And Hormonal Abnormalities, Hala Ibrahim Mohamed, Ahmad Mohamad Abbas Elseasi

Journal of Medicine in Scientific Research

Background Sexual dysfunction and hormonal imbalance are common in males with end-stage renal disease (ESRD), particularly among those on chronic hemodialysis. Kidney transplantation may restore endocrine homeostasis and improve sexual function. This study aimed to compare the effects of hemodialysis and renal transplantation on male sexual function and related hormonal profiles. Methods This cross-sectional study was conducted on 40 married men (≥18 years) with ESRD at National Institute of Urology and Nephrology from October 2024 to October 2025. Participants were divided into two groups: Group I (hemodialysis) and Group II (renal transplantation). Clinical evaluation, laboratory tests, and hormonal assays (Folliclestimulating …

Transcortical Approach For Central Neurocytoma: Efficacy, Safety, And Functional Outcome, Eslam Abozied Kandil

Journal of Medicine in Scientific Research

Background Central neurocytoma (CN) is a rare intraventricular neuronal tumor that predominantly affects young adults and is frequently associated with obstructive hydrocephalus. Surgical resection remains the cornerstone of treatment, yet the optimal surgical corridor and predictors of long-term outcome remain debated. Objective To evaluate the efficacy, safety, functional outcomes, and oncological control of transcortical microsurgical resection for central neurocytoma at a single neurosurgical center. Methods A retrospective review was conducted of all patients undergoing transcortical resection of central neurocytoma between 2017 and 2025. Clinical presentation, radiological characteristics, surgical approach, extent of resection, cerebrospinal fluid (CSF) diversion, postoperative complications, functional outcomes, …

The Impact And Prevalence Of Pain In Adolescents And Children Living With Type-One Diabetes Mellitus, Randa Mohamed Darwish, Ayat Ibrahim Ghanem, Lamis Safwat Mubarak

Journal of Medicine in Scientific Research

Background: Pain is frequent but often underrated and even overlooked in adolescents and children living with type-one diabetes mellitus and can negatively impact their quality of life(QoL) and their cooperation within the management plan. Objective: To discern the common types , severity and prevalence of pain in pediatrics living with type-one-diabetes;compared to the group of diabetes-free control, and to probe associations with glycemic control, fatigue, and (QoL). Methods: This cross-sectional study incorporated 102 adolescents and children withtype -one- diabetesmellitus; and 99 age- and sex-matched healthy peers aged 8- 16 years. Pain intensity was evaluated using the (body-pain) domain in the …

Atrial Fibrillation After Off-Pump Versus On-Pump Coronary Artery Bypass Grafting Surgery, Ahmed Abdalla Mohamed, Ahmed M Elshemy, Sherif M Elboghdady, Wael S Nekhila, Azza A Katta

Journal of Medicine in Scientific Research

Background Among postoperative arrhythmic complications, atrial fibrillation (AF) exhibits the greatest prevalence after coronary artery bypass grafting (CABG). This study investigates the comparative prevalence of AF between on-pump and off-pump techniques. Aim To compare the POAF (post-operative atrial fibrillation) incidence between off-pump and on-pump CABG Methods A randomized (simple) cohort study prospectively investigated the influence of surgical practice in CABG, contrasting off-pump (OPCAB) and on-pump (ONCAB) methods, on the early postoperative occurrence of atrial fibrillation (POAF), defined as within the first 24 hours post-surgery. In a cohort of 128 consecutive patients (95 off-pump, 33 on-pump), the study compared groups based …

Evaluation Of Left Cardiac Chamber And Cardiac Size With Non Ecg Gated Ct In Cancer Patients And Its Role In Determining Cardiomyopathy, Manal Mohamed Refaat Beshir, Samia Yehia Heikal, Shaimaa Abdalaleem Abdalgeleel, Dalia Ibraheem El Saied, Sarah Mamdouh Osman

Journal of Medicine in Scientific Research

Background: A number of cardiovascular processes have been linked to cardiac chamber and cardiac size increase as a significant biomarker for predicting morbidity and death. There is no standardized technique for assessing and reporting cardiac chamber and cardiac size, despite the fact that non-electrocardiographically (ECG) gated multidetector CT is a frequently utilized cross-sectional imaging modality to assess numerous cardiothoracic diseases . Patients and Methods :Our study encompassed 106 patients. All patients were diagnosed with primary cancer and underwent computed tomography (CT) for either initial evaluation or subsequent monitoring. Cardiac measurements were obtained in CT and compared to Echocardiographic results done …

Association Of Arterial Partial Oxygen Pressure With Mortality In Critically Ill Patients With Sepsis: An Observational Prospective Cohort Study, Talal Ibrahim Mostafa Hagag, Salwa M.A. Dahesh

Journal of Medicine in Scientific Research

Background Up till now, the best oxygenation plan in sepsis is a moot point. Although both hypoxemia and hyperoxemia have been linked to negative outcomes, it is unclear whether the arterial oxygen tension (PaO₂) contributes to mortality on its own. The present study aimed to study the association between the arterial partial oxygen pressure and the mortality among critically ill patients with sepsis. Methods A prospective observational study was carried out, including 120 critically ill patients with sepsis. The patients were classified according to arterial partial oxygen pressure into two groups: the PaO₂ >80 mmHg group, which included 61 patients, …

Applicability Of The Cleveland Clinic Scoring Tool For The Risk Prediction Of Acute Kidney Injury After Adult Cardiac Surgery., Ahmed A Faragalla, Ahmed M Elshiemy, Wael S Nekhila, Sherif M Elboghdady

Journal of Medicine in Scientific Research

Background Post-cardiac surgery acute kidney injury (AKI) is a significant complication associated with increased mortality, longer ICU stays, and higher healthcare costs. The Cleveland Clinic Scoring Tool (CCST) aids preoperative risk evaluation, facilitating tailored prevention strategies. Aim This study evaluates the relevance of the CCST in prospectively assessing AKI risk in adult patients undergoing various cardiac surgeries. Methods This prospective cohort study (tertiary centre, Jan 2021-Aug 2023) assessed the CCST for preoperative AKI risk in adult open-heart surgery (OHS) patients. Consenting adults (≥18) undergoing elective/emergency OHS were included, excluding those with pre- AKI (KDIGO), dialysis-dependent ESRD, aortic dissection, shock, or …

The Postoperative Analgesic Effect Of Lumbar Erector Spinae Plane Block Versus Pericapsular Nerve Group Block In Patients Undergoing Hip Surgeries, Islam M. El-Desoky, Mohamed Elshafey, Amal Ismail Abdelrahman

Journal of Medicine in Scientific Research

Background: Hip surgery requires effective pain control for proper recovery and decreasing the length of hospital stay. Aims: We aimed to assess the analgesic effect of Erector spinae plane block (ESPB) and pericapsular nerve group (PENG) blocks in pain control after hip operations. Methods: This randomized clinical trial included 69 ASA I–II patients scheduled for hip surgery were randomly allocated into three groups: PENG block, ESPB, and control groups (23 each). The primary outcome was postoperative pain assessed via the Numeric Rating Scale (NRS) at rest and during movement. Secondary outcomes included intraoperative and 48-hour morphine consumption, time to first …

The Role Of Human Sarcosine Dehydrogenase And Endothelial Growth Factor In Early Diagnosis Of Cancer Prostate, Hala Ibrahim Mohamed, Amr Mohamed Mounier Elsofy

Journal of Medicine in Scientific Research

Background: As the second most common cancer in males, prostate cancer contributes significantly to cancer-related deaths. Prostate-specific antigen (PSA) test and digital rectal examinations are used to identify it, albeit PSA screenings frequently produce unreliable results. Initial symptoms may include sexual dysfunction and urinary problems. The standard diagnostic method is biopsies, which are carried out under the direction of ultrasound or magnetic resonance imaging (MRI). However, they are risky and can result in infections and erectile dysfunction, which emphasizes the need for better biomarkers. Sarcosine and vascular endothelial growth factor are important metabolites associated with the progression of prostate cancer, …

Role Of New-Onset Qt Prolongation In Ecg In Critically Ill Septic Patients As A Prognostic Tool: An Observational Prospective Cohort Icu Study, Talal Ibrahim Mostafa Hagag, Salwa M.A. Dahesh

Journal of Medicine in Scientific Research

Background QT interval prolongation is a common finding among critically ill patients and could be a marker of autonomic nervous dysregulation, instability of metabolism, and/or septic cardiomyopathy. Nevertheless, its prognostic role among septic ICU populations remains unclarified. The current aim of this study was to explore its potential role regarding short-term mortality. Methods In this cohort study, 119 septic adults were included in the study within 24 hours of ICU admission. Demographics, clinical variables, lab values, and QTc intervals were measured within 2 hours of ICU admission following exclusion for clinically significant electrolyte imbalances and use of QT-prolonging medications. QTc …

Facial Expression With Type Of Eye Opening Associates With Multi-Organ Failure: An Observational Prospective Icu Cohort Study, Talal Ibrahim Mostafa Hagag

Journal of Medicine in Scientific Research

Title Facial expression with the type of eye opening associates with multi-organ failure: an Observational prospective ICU cohort study Background Accurate prognostication in the intensive care unit (ICU) remains a challenging task. Conventional severity scores such as the Acute Physiology and Chronic Health Evaluation II (APACHE II) quantify physiological derangement but overlook real-time neurological and affective responsiveness. Behavioral indicators—particularly facial expressivity and eye-opening response—may reflect cortical and brainstem integrity, offering a simple, non-invasive adjunct for bedside mortality prediction. Methods In this single-center, prospective observational study, 210 adult patients in the ICU were assessed within 24 hours of admission. Two blinded …

Frequency Of Carpal Tunnel Syndrome Presenting With Symptoms In An Ulnar Nerve Distribution In A Prospective Study, Wessam Eissa Hamed

Journal of Medicine in Scientific Research

Objective Assessing frequency of pain and/or paresthesia in the ulnar nerve distribution in patients documented electro-diagnostically with median mononeuropathy at the wrist (MNW). Although occurrence of this clinical symptom has been explored in some literature but remains unaddressed. Method Study participants were assessed to measure the distribution and intensity of their symptoms in hand using the Katz hand diagram and the Boston Carpal Tunnel Questionnaire-Symptom Severity Scale (BCTQ-SSS). 30 participants satisfied the study's criteria regarding ulnar neuropathy and completed a clinical examination. All participants also were subjected to nerve ultrasonography and electro-diagnostic study. Results Isolated median mononeuropathy at the wrist …