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Articles 13591 - 13620 of 21762
Full-Text Articles in Medical Specialties
Pan-Cancer Molecular Subtypes Of Metastasis Reveal Distinct And Evolving Transcriptional Programs, Yiqun Zhang, Fengju Chen, Chad J Creighton
Pan-Cancer Molecular Subtypes Of Metastasis Reveal Distinct And Evolving Transcriptional Programs, Yiqun Zhang, Fengju Chen, Chad J Creighton
Faculty, Staff and Students Publications
Molecular mechanisms underlying cancer metastasis span diverse tissues of origin. Here, we synthesize and collate the transcriptomes of patient-derived xenografts and patient tumor metastases, and these data collectively represent 38 studies and over 3,000 patients and 4,000 tumors. We identify four expression-based subtypes of metastasis transcending tumor lineage. The first subtype has extensive copy alterations, higher expression of MYC transcriptional targets and DNA repair genes, and bromodomain inhibitor response association. The second subtype has higher expression of genes involving metabolism and prostaglandin synthesis and regulation. The third subtype has evidence of neuronal differentiation, higher expression of DNA and histone methylation …
Slo3 In The Fast Lane: The Latest Male Contraceptive Target With A Promising Small-Molecule Inhibitor, Zhi Tan, Thomas X Garcia
Slo3 In The Fast Lane: The Latest Male Contraceptive Target With A Promising Small-Molecule Inhibitor, Zhi Tan, Thomas X Garcia
Faculty, Staff and Students Publications
No abstract provided.
Lacrimal Gland Epithelial Cells Shape Immune Responses Through The Modulation Of Inflammasomes And Lipid Metabolism, Vanessa Delcroix, Olivier Mauduit, Menglu Yang, Amrita Srivastava, Takeshi Umazume, Cintia S De Paiva, Valery I Shestopalov, Darlene A Dartt, Helen P Makarenkova
Lacrimal Gland Epithelial Cells Shape Immune Responses Through The Modulation Of Inflammasomes And Lipid Metabolism, Vanessa Delcroix, Olivier Mauduit, Menglu Yang, Amrita Srivastava, Takeshi Umazume, Cintia S De Paiva, Valery I Shestopalov, Darlene A Dartt, Helen P Makarenkova
Faculty, Staff and Students Publications
Lacrimal gland inflammation triggers dry eye disease through impaired tear secretion by the epithelium. As aberrant inflammasome activation occurs in autoimmune disorders including Sjögren's syndrome, we analyzed the inflammasome pathway during acute and chronic inflammation and investigated its potential regulators. Bacterial infection was mimicked by the intraglandular injection of lipopolysaccharide (LPS) and nigericin, known to activate the NLRP3 inflammasome. Acute injury of the lacrimal gland was induced by interleukin (IL)-1α injection. Chronic inflammation was studied using two Sjögren's syndrome models: diseased
Comparison Of Dna Extraction Methods For Soft Tissue Samples, Steve Guzman, Nathaniel E. Hill, Mujtaba Shah, Jonathon Reynolds, Cole Farnsworth, Molly Henley, Alfred Amendolara, Laura Minor, John Dougherty Jr., John A. Kriak, Kyle B. Bills, David W. Sant
Comparison Of Dna Extraction Methods For Soft Tissue Samples, Steve Guzman, Nathaniel E. Hill, Mujtaba Shah, Jonathon Reynolds, Cole Farnsworth, Molly Henley, Alfred Amendolara, Laura Minor, John Dougherty Jr., John A. Kriak, Kyle B. Bills, David W. Sant
Annual Research Symposium
No abstract provided.
Vitamin C Contributes To Epigenetic Regulation Of Genes Related To Diabetic Retinopathy In Retinal Endothelial Cells, Elizabeth L. Turner, Jonathon Reynolds, Walker Kay, Marianne Becnel, Matthew Conway, Alexander Kim, John A. Kriak, Kyle B. Bills, David W. Sant
Vitamin C Contributes To Epigenetic Regulation Of Genes Related To Diabetic Retinopathy In Retinal Endothelial Cells, Elizabeth L. Turner, Jonathon Reynolds, Walker Kay, Marianne Becnel, Matthew Conway, Alexander Kim, John A. Kriak, Kyle B. Bills, David W. Sant
Annual Research Symposium
No abstract provided.
Determination Of Feasibility And Plausibility Of Using Various Biological Samples For Remote Genetic Testing, Cole Farnsworth, Molly Henley, Walker Kay, Varos Victer Manukyan, Jonathon Reynolds, John A. Kriak, Kyle B. Bills, David W. Sant
Determination Of Feasibility And Plausibility Of Using Various Biological Samples For Remote Genetic Testing, Cole Farnsworth, Molly Henley, Walker Kay, Varos Victer Manukyan, Jonathon Reynolds, John A. Kriak, Kyle B. Bills, David W. Sant
Annual Research Symposium
No abstract provided.
Development Of An Affordable, Manual Method Of Dna Extraction From Bones And Teeth , Varos Victer Manukyan, Lara Laughrey, Ryan V. Powers, Amar Paul, Davis Johnston, Dashon Eure, Todeh Toomians, John A. Kriak, Kyle B. Bills, David W. Sant
Development Of An Affordable, Manual Method Of Dna Extraction From Bones And Teeth , Varos Victer Manukyan, Lara Laughrey, Ryan V. Powers, Amar Paul, Davis Johnston, Dashon Eure, Todeh Toomians, John A. Kriak, Kyle B. Bills, David W. Sant
Annual Research Symposium
No abstract provided.
Breast Cancer Subtyping Of The Cancer Genome Atlas (Tcga) Samples, Spencer E. Yu, Alfred B. Amendolara, Steven T. Tung, Alexander P. Sheppert, Nasif Islam, Mindy Cook, Lena Diprizito, Nicole Lashiker, Roshni Jogin, John A. Kriak, Kyle B. Bills, David W. Sant
Breast Cancer Subtyping Of The Cancer Genome Atlas (Tcga) Samples, Spencer E. Yu, Alfred B. Amendolara, Steven T. Tung, Alexander P. Sheppert, Nasif Islam, Mindy Cook, Lena Diprizito, Nicole Lashiker, Roshni Jogin, John A. Kriak, Kyle B. Bills, David W. Sant
Annual Research Symposium
No abstract provided.
The Immunomodulating Effects Of Morphine Dependence And Withdrawal In Rat Lung, Liver, Spleen And Blood, Yensi Munoz
The Immunomodulating Effects Of Morphine Dependence And Withdrawal In Rat Lung, Liver, Spleen And Blood, Yensi Munoz
Annual Research Symposium
No abstract provided.
The Immunomodulating Effects Of Morphine Dependence And Withdrawal In A Rat Model, Mark Stoll
The Immunomodulating Effects Of Morphine Dependence And Withdrawal In A Rat Model, Mark Stoll
Annual Research Symposium
Would you like to know what happens to the immune system during opioid drug withdrawal?
Anti-Diabetic Drug, Semaglutide, Prevents Doxorubicin-Induced Cardiotoxicity, Sandra Bakhit, Kota Ramana
Anti-Diabetic Drug, Semaglutide, Prevents Doxorubicin-Induced Cardiotoxicity, Sandra Bakhit, Kota Ramana
Annual Research Symposium
No abstract provided.
Carvacrol Regulates Endotoxin -Induced Arachidonic Acid Metabolism., Aliea M. Jalali, Spencer Norton
Carvacrol Regulates Endotoxin -Induced Arachidonic Acid Metabolism., Aliea M. Jalali, Spencer Norton
Annual Research Symposium
Plant-derived essential oil prevents endotoxin-induced inflammatory response
A Systematic Review: Toxoplasma Gondii Infection And Drugs Of Abuse, Amani Sastry
A Systematic Review: Toxoplasma Gondii Infection And Drugs Of Abuse, Amani Sastry
Annual Research Symposium
No abstract provided.
The Current State Of Underrepresented Osteopathic Minorities In Competitive Specialties, Emmanuel Oyalabu, Steve Guzman, Dashon Eure, Ezenna Obilor
The Current State Of Underrepresented Osteopathic Minorities In Competitive Specialties, Emmanuel Oyalabu, Steve Guzman, Dashon Eure, Ezenna Obilor
Annual Research Symposium
It is well documented that barriers exist for underrepresented minorities to enter the field of medicine and even more competitive residencies. As defined by the NRMP, competitive specialties include but are not limited to Interventional Radiology, Orthopedic Surgery, Plastic Surgery, Radiation Oncology, Vascular Surgery, Neurosurgery, Dermatology, and Otornylogy (NRMP-AMA). A large number of osteopathic medical school graduates have a history of going into primary care specialties because many osteopathic medical schools have a primary care focus (Primary Care- Osteopathic Medicine). The emphasis on primary care, whether intentional or not, can foster a less-than-advantageous environment for underrepresented minority students (URM), pursuing …
Appearance Of Two Distinct Clusters Of Glucose Dysregulation In Chronic Intractable Migraine, Roshni Jogin, Kaitlyn Mcfarland, Aparna Naik, Tanner Williford, Matthew Conway, Amar Paul, John A. Kriak, David W. Sant, Kyle B. Bills
Appearance Of Two Distinct Clusters Of Glucose Dysregulation In Chronic Intractable Migraine, Roshni Jogin, Kaitlyn Mcfarland, Aparna Naik, Tanner Williford, Matthew Conway, Amar Paul, John A. Kriak, David W. Sant, Kyle B. Bills
Annual Research Symposium
No abstract provided.
Heterodyned Whole-Body Vibration Ameliorates Anxiety In Opioid-Use Disorder, Kailee Edwards, Braden Cunningham, Alfred Amendolara, Marryam Anwar, Jon Gonzales, Roshni Jogin, Wyatt Magoffin, Amar Paul, Ryan Perry, James Pike, Nathan Swallow, Steven Tung, Mary Seamons, Andrew Payne, John A. Kriak, David W. Sant, David W. Sant
Heterodyned Whole-Body Vibration Ameliorates Anxiety In Opioid-Use Disorder, Kailee Edwards, Braden Cunningham, Alfred Amendolara, Marryam Anwar, Jon Gonzales, Roshni Jogin, Wyatt Magoffin, Amar Paul, Ryan Perry, James Pike, Nathan Swallow, Steven Tung, Mary Seamons, Andrew Payne, John A. Kriak, David W. Sant, David W. Sant
Annual Research Symposium
No abstract provided.
Development Of A Neural Network Model To Identify Abnormalities In Cervical X-Rays, Alex P. Sheppert, Nasif Islam, Race Peterson, Michael T. Sullivan, John A. Kriak, David W. Sant, Kyle B. Bills
Development Of A Neural Network Model To Identify Abnormalities In Cervical X-Rays, Alex P. Sheppert, Nasif Islam, Race Peterson, Michael T. Sullivan, John A. Kriak, David W. Sant, Kyle B. Bills
Annual Research Symposium
No abstract provided.
Planning A Review Of The Pathogenesis And Management Of Valley Fever, Seattle Shakur
Planning A Review Of The Pathogenesis And Management Of Valley Fever, Seattle Shakur
Annual Research Symposium
No abstract provided.
Clinical Trial Subject Recruitment: Research Immersion Experience, Brooklyn Janes
Clinical Trial Subject Recruitment: Research Immersion Experience, Brooklyn Janes
Annual Research Symposium
No abstract provided.
Staff At Increased Risk For Computer Vision Syndrome Compared To Faculty At An Osteopathic Medical School With An Electronic Content Delivery Model, Joseph Bachman
Annual Research Symposium
No abstract provided.
Sulopenem For The Treatment Of Complicated And Uncomplicated Bacterial Urinary Tract Infection (Uti), Aiyi Chen, Thanh-Liem Vu, Daniel J. Yang, Landon Olsen
Sulopenem For The Treatment Of Complicated And Uncomplicated Bacterial Urinary Tract Infection (Uti), Aiyi Chen, Thanh-Liem Vu, Daniel J. Yang, Landon Olsen
Annual Research Symposium
No abstract provided.
Eflapegrastim-Xnst: A New Agent To Prevent Antineoplastic Chemotherapy-Induced Febrile Neutropenia, Gary Lynch
Eflapegrastim-Xnst: A New Agent To Prevent Antineoplastic Chemotherapy-Induced Febrile Neutropenia, Gary Lynch
Annual Research Symposium
No abstract provided.
Focus Group Interview Experience Of A University Clinical Research Team, Kade Janes
Focus Group Interview Experience Of A University Clinical Research Team, Kade Janes
Annual Research Symposium
No abstract provided.
Development Of A Census Driven Equation To Predict Non-Billable "Cross-Cover" Work Done During Nocturnist Shifts To Predict Staffing, Bibhash Neupane
Development Of A Census Driven Equation To Predict Non-Billable "Cross-Cover" Work Done During Nocturnist Shifts To Predict Staffing, Bibhash Neupane
Annual Research Symposium
No abstract provided.
Assessment Of Nutrition Care Needs In The Management Of Pediatric Patients With Rare Disease, Elizabeth Turner, Kayla Woodring, Marianne Becnel, Saisha Kataria, Esther Nuebel
Assessment Of Nutrition Care Needs In The Management Of Pediatric Patients With Rare Disease, Elizabeth Turner, Kayla Woodring, Marianne Becnel, Saisha Kataria, Esther Nuebel
Annual Research Symposium
2023 Roseman University Research Symposium: Poster Session
Roseman Research Symposium, Manas Mandal
Roseman Research Symposium, Manas Mandal
Annual Research Symposium
No abstract provided.
Emergence Of Dental Nanomaterials: “Their Role In Performing Endodontic Therapy”, Chandrika Nama, John Wisniewski Dr.
Emergence Of Dental Nanomaterials: “Their Role In Performing Endodontic Therapy”, Chandrika Nama, John Wisniewski Dr.
Annual Research Symposium
No abstract provided.
The Impact Of A Hospital Protocol In Neonates At Risk For Neonatal Abstinence Syndrome (Nas), Victoria Pang
The Impact Of A Hospital Protocol In Neonates At Risk For Neonatal Abstinence Syndrome (Nas), Victoria Pang
Annual Research Symposium
No abstract provided.
New Year, New Variant Or A Subvariant Of Old Omicron?, Parker Grossman, Manas Mandal
New Year, New Variant Or A Subvariant Of Old Omicron?, Parker Grossman, Manas Mandal
Annual Research Symposium
No abstract provided.
Referral Patterns Of Neonatal Healthcare Professionals For Cleft Lip And Palate Patients, Alyssa Morrow
Referral Patterns Of Neonatal Healthcare Professionals For Cleft Lip And Palate Patients, Alyssa Morrow
Annual Research Symposium
No abstract provided.