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Articles 1261 - 1290 of 2755
Full-Text Articles in Medical Specialties
Utility Of Bedside Ultrasound In Identifying Undiagnosed Malpresentation Upon Admission To Labor And Delivery: A Quality Improvement Project, Kristen Daugherty, Gloria Wang, Samantha Mclean, Jeffrey Johnson, Kelly Mosher
Utility Of Bedside Ultrasound In Identifying Undiagnosed Malpresentation Upon Admission To Labor And Delivery: A Quality Improvement Project, Kristen Daugherty, Gloria Wang, Samantha Mclean, Jeffrey Johnson, Kelly Mosher
Continental, MidAmerica, & Mountain Divisions GME Research Day 2024
No abstract provided.
Retrospective Analysis Of Surgical Time Proficiency During Laparoscopic Myomectomies, Jeffrey Johnson, Kimberly Swan, Errick Arroyo
Retrospective Analysis Of Surgical Time Proficiency During Laparoscopic Myomectomies, Jeffrey Johnson, Kimberly Swan, Errick Arroyo
Continental, MidAmerica, & Mountain Divisions GME Research Day 2024
No abstract provided.
Recurrent Intussusception In Child Despite Repeated Surgical Correction, Carlos Cordova, Alexandra Lawlor, Tillie Schumann, Sydney Solomon, Lily Wiedrich
Recurrent Intussusception In Child Despite Repeated Surgical Correction, Carlos Cordova, Alexandra Lawlor, Tillie Schumann, Sydney Solomon, Lily Wiedrich
East Florida Division GME Research Day 2024
No abstract provided.
Comparing Large Language Models Accuracy In Following Interval Surveillance Colonoscopy Guidelines, Olufemi Osikoya, Gregory Brennan
Comparing Large Language Models Accuracy In Following Interval Surveillance Colonoscopy Guidelines, Olufemi Osikoya, Gregory Brennan
North Texas GME Research Forum 2024
Introduction: Providing pathology results and appropriate recommendations after resection of colon polyps is mandatory. Large language models (LLMs) such as ChatGPT and Google Bard, have shown promise in clinical workflows such as pathology results letters. We tested whether LLMs could provide appropriate surveillance recommendations based on current guidelines from the US multi-society task force for post-colonoscopy follow-up. Methods: Our aim was to compare the accuracy of ChatGPT 3.5, ChatGPT 4, and Google Bard in providing appropriate interval surveillance recommendations. An example prompt being “Write a patient pathology result letter after a colonoscopy with one tubular adenoma polyp (< 10mm) resected. Include recommendations for when the next surveillance colonoscopy should be completed.” Seventeen different post polypectomy surveillance queries and responses were analyzed (correct, partially correct, incorrect) compared to USMSTF guidelines. Results: When …
The Ethical Concerns Of Improper Semaglutide Administration After Acquisition From A Compounded Pharmacy, Syed Basit Haider, Renu Thomas, E’Joven Reed, Aneesha Shaju, Bushra Bangash, Jakob Schnell, Edrianna Mae Ablola
The Ethical Concerns Of Improper Semaglutide Administration After Acquisition From A Compounded Pharmacy, Syed Basit Haider, Renu Thomas, E’Joven Reed, Aneesha Shaju, Bushra Bangash, Jakob Schnell, Edrianna Mae Ablola
Gulf Coast Division GME Research Symposium 2024
No abstract provided.
Advancing School Nursing Practice: A Novel Approach To Screening For Gastrointestinal Disorders In Children, Ashley Bunting, Isabella Cavlan
Advancing School Nursing Practice: A Novel Approach To Screening For Gastrointestinal Disorders In Children, Ashley Bunting, Isabella Cavlan
Nursing | Student Research Posters
California schools currently only screen for vision and hearing, leaving many other health concerns unaddressed. Among these, gastrointestinal (GI) health is particularly significant, as digestive disorders can lead to severe consequences, like malnutrition and stunted growth. By incorporating routine GI screenings, school nurses can promote the early detection of disease, allowing for timely intervention and improved health outcomes in children.
Based on existing literature, we have developed a novel pediatric GI screening tool for school nurses to use in routine screenings, presented below.
Efficient Classification Of Very High Resolution Images, Mohammad I. Nouyed
Efficient Classification Of Very High Resolution Images, Mohammad I. Nouyed
Graduate Theses, Dissertations, and Problem Reports (ETD)
In recent decades, deep learning approaches have shown significant improvement in various image understanding tasks. However, analysis of high-resolution images remains a major challenge. In this work, we address the challenge of very high-resolution histopathological image (VHRHI) classification using a new information-theoretic discriminative patch selection approach. We show results on a high-resolution image dataset, namely, gigapixel whole slide tissue images for cancer tumors. Then we address how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. These ``weak labels'' are applied throughout the image but describe tumor regions of variable sizes and …
Foreign Body Removed Through Laparotomy: A Case Report And Literature Review, Kayla Nguyen, Duyen Quach, David Ortiz, Dominique Norris, Srinivas Ramireddy, Jody Smith
Foreign Body Removed Through Laparotomy: A Case Report And Literature Review, Kayla Nguyen, Duyen Quach, David Ortiz, Dominique Norris, Srinivas Ramireddy, Jody Smith
Gulf Coast Division GME Research Symposium 2024
No abstract provided.
Deficiency In Detail Among Ventral Hernia Repair Operative Notes And The Impact On Patient Outcomes, Alexys N. Ramos, Duyen Quach, Kayla Nguyen, Said Maldonado, Nicole B. Lyons, Jonathan S. Lall, Scott Zimmerle, Brendan Rosamond, Ashlynn Mills, Yoolim Alex Seo, Angelica C. Rodriguez, Mike Liang
Deficiency In Detail Among Ventral Hernia Repair Operative Notes And The Impact On Patient Outcomes, Alexys N. Ramos, Duyen Quach, Kayla Nguyen, Said Maldonado, Nicole B. Lyons, Jonathan S. Lall, Scott Zimmerle, Brendan Rosamond, Ashlynn Mills, Yoolim Alex Seo, Angelica C. Rodriguez, Mike Liang
Gulf Coast Division GME Research Symposium 2024
No abstract provided.
Intracrnial Hemorrhage And Ecg Changes, Negar Niknam, Eric N. Riha, Bushra Bangash, Parshvi Patel, Skantha K. Manjunath, Gnananandh Jayaraman, Ramesh Kesavan, Siva T. Sarva
Intracrnial Hemorrhage And Ecg Changes, Negar Niknam, Eric N. Riha, Bushra Bangash, Parshvi Patel, Skantha K. Manjunath, Gnananandh Jayaraman, Ramesh Kesavan, Siva T. Sarva
Gulf Coast Division GME Research Symposium 2024
No abstract provided.
Unusual Delayed Invasive Infection With Staphylococcus Capitis Following Coronary Artery Bypass Grafting: A Case Report And Literature Review, Suhas Tatapudi, Daniel J. Avila Castillo, Ibrahim Yazji
Unusual Delayed Invasive Infection With Staphylococcus Capitis Following Coronary Artery Bypass Grafting: A Case Report And Literature Review, Suhas Tatapudi, Daniel J. Avila Castillo, Ibrahim Yazji
Gulf Coast Division GME Research Symposium 2024
No abstract provided.
Novel Engineering Approaches For Orthopedic Injury Treatment And Infection Diagnosis, Cynthia Co
Novel Engineering Approaches For Orthopedic Injury Treatment And Infection Diagnosis, Cynthia Co
Bioengineering Dissertations - Archive
Bioengineering has made significant contributions to the treatment of orthopedic injury through interdisciplinary approaches. Central to these advancements are many orthopedic implants, including anchors and joint replacements, which have been designed to restore mobility. Despite their functional efficacy, these products have limited lifespan and are associated with many complications, such as implant-associated infection. The success of implant design and function, both in the short and long term, is paramount for enhancing patient outcomes and overall well-being. Therefore, my thesis work is dedicated to addressing these critical challenges, aiming to maximize their treatment effect while minimizing the implant-associated complications.
Long-term patient …
Basic Principles Of Chronic Wound Care Management, Mahi-Ruhi Ladhani Jain
Basic Principles Of Chronic Wound Care Management, Mahi-Ruhi Ladhani Jain
Capstone Showcase
This CME article aims to address the basics of chronic wound management, especially related to chronic venous insufficiency, peripheral arterial disease, and diabetes. Many providers do not know how to treat or manage chronic wounds and may use outdated methods to treat the wounds. There are many wound care supplies and resources available for providers when it comes to wound care management. However, the information is spread out across different resources. This article aims to create a resource that allows one to have a basic understanding of wounds and the different ways to manage them. In the article, I will …
Early Outcome Of Mini-Mvs Surger Y Elsherif Et Al., Mahmoud Abdullghany Amin Elsherif, Rasha Hosny, Mohamed Ramadan Mohamed
Early Outcome Of Mini-Mvs Surger Y Elsherif Et Al., Mahmoud Abdullghany Amin Elsherif, Rasha Hosny, Mohamed Ramadan Mohamed
Journal of Medicine in Scientific Research
Background: The conventional incision adopted to for mitral valve replacement is the full sternotomy, with proved over time and experience to be a simple and safe method. Minimal invasive mitral valve surgery (Mini-MVS) is an alternative approach for elective mitral surgeries that proved over the last years to be a promising option.
Aim of the study: Assessment of the early outcome of minimally invasive mitral valve surgery with or without tricuspid surgery.
Methods: A retrospective study on 100 consecutive patients who underwent minimal invasive mitral valve surgery from January 2021 to June 2023 at National Heart Institute in Egypt.
Results: …
Influences Of Athletic Trainers' Return-To-Activity Assessments For Patients With An Ankle Sprain, Ryan S. Mccann, Cailee E. Welch Bacon, Ashley M. B. Suttmiller, Phillip A. Gribble, Julie M. Cavallario
Influences Of Athletic Trainers' Return-To-Activity Assessments For Patients With An Ankle Sprain, Ryan S. Mccann, Cailee E. Welch Bacon, Ashley M. B. Suttmiller, Phillip A. Gribble, Julie M. Cavallario
Rehabilitation Sciences Faculty Publications
Context: Athletic trainers (ATs) inconsistently apply rehabilitation-oriented assessments (ROASTs) when deciding return-to-activity readiness for patients with an ankle sprain. Facilitators and barriers that are most influential to ATs' assessment selection remain unknown.
Objective: To examine facilitators of and barriers to ATs' selection of outcome assessments when determining return-to-activity readiness for patients with an ankle sprain.
Design: Cross-sectional study.
Setting: Online survey.
Patients or other participants: We sent an online survey to 10 000 clinically practicing ATs. The survey was accessed by 676 individuals, of whom 574 submitted responses (85% completion rate), and 541 respondents met the inclusion criteria.
Main outcome …
Heterogeneity In The Role Of Emergency Physicians And Treatment Of Acute Atrial Fibrillation In Emergency Departments— Results Of The International Atrial Fibrillation Background (Afib) Study, Markus Holmberg, Ville Hällberg, Hjalti M. Björnsson, Timothy H. Rainer, Colin A. Graham, Marc B. Sabbe, Wilhelm Behringer, Gayle Galletta, Hans Domanovits, Harri Pikkarainen, Bruce M. Lo, Christopher Laurent, Pascal Vanelderen, Ari Palomäki
Heterogeneity In The Role Of Emergency Physicians And Treatment Of Acute Atrial Fibrillation In Emergency Departments— Results Of The International Atrial Fibrillation Background (Afib) Study, Markus Holmberg, Ville Hällberg, Hjalti M. Björnsson, Timothy H. Rainer, Colin A. Graham, Marc B. Sabbe, Wilhelm Behringer, Gayle Galletta, Hans Domanovits, Harri Pikkarainen, Bruce M. Lo, Christopher Laurent, Pascal Vanelderen, Ari Palomäki
Department of Emergency Medicine Faculty Publications
The consept of emergency departments (EDs) with specialized teams of emergency physicians originated in the United Kingdom and the United States during the 1970s and was expanded across most European countries in the twenty-first century. Among the various cardiac arrhythmias encountered in EDs, atrial fibrillation (AF) is the most prevalent, contributing to ED congestion. Existing guidelines offer multiple treatment options for acute-onset AF occurring within 48 hours. The aim of The Atrial Fibrillation Background Study is to evaluate treatment strategies, practices and the role of emergency physicians in managing acute-onset AF in Western medical tradition across Europe, the United States …
The Unequal Distribution Of Social Risk For Black Men Across The Life-Span. A Novel Framework., Waleed Y. Sami
The Unequal Distribution Of Social Risk For Black Men Across The Life-Span. A Novel Framework., Waleed Y. Sami
Adultspan Journal
This conceptual overview offers a comprehensive overview of systemic pathways that negatively impact the mental health of Black Men throughout their lives. Our argument highlights the importance for counselors and mental health professionals to utilize a thorough social risk assessment that considers these pathways in order to effectively address the mental health needs of Black Men while fostering positive working relationships. This overview strongly advocates for the use of context and structural determinants when evaluating mental health symptoms. Without an appropriate understanding of social risk and determinants, counselors may inadvertently perpetuate disparities by decontextualizing symptomology, and reproducing racist discourse.
Machine-Learning-Enabled Diagnostics With Improved Visualization Of Disease Lesions In Chest X-Ray Images, Md. Fashiar Rahman, Tzu-Liang (Bill) Tseng, Michael Pokojovy, Peter Mccaffrey, Eric Walser, Scott Moen, Alex Vo, Johnny C. Ho
Machine-Learning-Enabled Diagnostics With Improved Visualization Of Disease Lesions In Chest X-Ray Images, Md. Fashiar Rahman, Tzu-Liang (Bill) Tseng, Michael Pokojovy, Peter Mccaffrey, Eric Walser, Scott Moen, Alex Vo, Johnny C. Ho
Mathematics & Statistics Faculty Publications
The class activation map (CAM) represents the neural-network-derived region of interest, which can help clarify the mechanism of the convolutional neural network’s determination of any class of interest. In medical imaging, it can help medical practitioners diagnose diseases like COVID-19 or pneumonia by highlighting the suspicious regions in Computational Tomography (CT) or chest X-ray (CXR) film. Many contemporary deep learning techniques only focus on COVID-19 classification tasks using CXRs, while few attempt to make it explainable with a saliency map. To fill this research gap, we first propose a VGG-16-architecture-based deep learning approach in combination with image enhancement, segmentation-based region …
The Effects Of Social Support On Recovery Outcomes Of Hip Fracture Patients, Preshecca Ragavan
The Effects Of Social Support On Recovery Outcomes Of Hip Fracture Patients, Preshecca Ragavan
Williams Honors College, Honors Research Projects
This literature review, completed under the guidance of Ms. Anuja Sarode-Paciorek from Summa Health - Akron, will investigate the effects of social support on the recovery outcomes of hip fracture patients. As part of this literature review, I will collect and analyze several scientific journal articles previously published on this topic to gain an overview of what prior knowledge clinical researchers have already gathered about this topic. As part of the analyses, each article will be thoroughly read and briefly summarized. Then, these summaries will be used to compile a list of a few strengths and a list of a …
Assessment Of Forensic And Clinical Criteria Of Orbital Blowout Fractures For Use In Bioarchaeological Analysis, Dylan E. Ornot
Assessment Of Forensic And Clinical Criteria Of Orbital Blowout Fractures For Use In Bioarchaeological Analysis, Dylan E. Ornot
Honors Undergraduate Theses
Orbital blowout fractures are a particular facial fracture occurring within the inner eye orbits of the face caused by blunt force trauma to the eyeball or the lower orbital rim. This fracture is common in modern clinical contexts due to physical assaults, but examining this fracture in skeletal material can also provide insights into the patterns of interpersonal violence within the fields of bioarchaeology and forensic anthropology. Issues with analyzing this fracture in skeletal material arise due to the clinical assessment practices of blowout fractures, where medical practitioners are highly focused on the soft tissue presentations of the fracture in …
Biomechanical Outcomes Of Distinct Tka Surgical Alignments And Implant Designs, Alexis Kathleen Nelson-Tranum
Biomechanical Outcomes Of Distinct Tka Surgical Alignments And Implant Designs, Alexis Kathleen Nelson-Tranum
Theses and Dissertations (ETD)
Introduction. Total knee arthroplasty (TKA) has advanced over the past two decades from traditional post-operative neutral alignment methods with an overall goal of implant longevity to ones that are more personalized to better replicate individual native knee kinematics. Personalizing TKA knee kinematics to better replicate a patient’s native knee kinematics has evolved in response to a reported 20% dissatisfaction by patients with their TKA. These personalization advancements include innovations in surgical alignment techniques include the kinematic alignment (KA) and joint line obliquity (JLO) restoration, in contrast to the mechanical alignment (MA) technique that places everyone into the same mold. Additionally, …
Genotypes Of Snps Of Key Genes Regulate Susceptibility And Drug Sensitivity To Neovascular Amd, Jinglin Cui
Genotypes Of Snps Of Key Genes Regulate Susceptibility And Drug Sensitivity To Neovascular Amd, Jinglin Cui
Theses and Dissertations (ETD)
Age-related macular degeneration (AMD), particularly its neovascular form, stands as a leading cause of blindness globally, with its prevalence in our country on a steady rise. This underscores the critical impact of neovascular AMD (nAMD) management on patient quality of life and societal burden. Current optimal treatments hinge on anti-vascular endothelial growth factor (anti-VEGF) therapies, though their efficacy varies across different drugs and individuals, highlighting the importance of precise drug selection in clinical outcomes. Research suggests that factors such as baseline vision, age, disease duration, lesion size, central retina thickness, neovascularization type, and demographic differences influence nAMD prognosis. In addition, …
The Validity And Reliability Of Ultrasound As A Tool For Assessing Skeletal Muscle Characteristics In The Pediatric Population, Elizabeth Seewer
The Validity And Reliability Of Ultrasound As A Tool For Assessing Skeletal Muscle Characteristics In The Pediatric Population, Elizabeth Seewer
Theses and Dissertations (ETD)
Annually, around 5 million people in the U.S. are admitted to Intensive Care Units (ICU) due to critical conditions, with pediatric patients comprising 21% of these admissions. Approximately 40% of pediatric ICU (PICU) patients require mechanical ventilation and extended stays, and about 6% result in death. Survivors often face long-term disabilities, including loss of skeletal muscle mass (SMM), a risk factor for morbidity and mortality. Abdominal computed tomography (CT) scans, often performed during PICU admissions, can assess muscle mass but pose risks of increased cost and radiation exposure. While CT and Magnetic Resonance Imaging (MRI) are gold standards for muscle …
Disseminated Coccidioidomycosis Discovered Through Skin Biopsy In A Pregnant Patient From Mexico, Henry Lim, Christina Guo, Marshall Hall, Christian Scheufele, Christopher M. Wong, Michael Carletti, Stephen Weis
Disseminated Coccidioidomycosis Discovered Through Skin Biopsy In A Pregnant Patient From Mexico, Henry Lim, Christina Guo, Marshall Hall, Christian Scheufele, Christopher M. Wong, Michael Carletti, Stephen Weis
North Texas GME Research Forum 2024
Introduction: Coccidioidomycosis is an infection caused by the organism Coccidioides immitis, a fungus endemic to the southwestern United States, Mexico, Central and South America. The presentation of coccidioidomycosis can range from symptoms resembling a simple upper respiratory infection, such as cough, to more severe systemic symptoms including fever, malaise, and chills. Cutaneous lesions of coccidioidomycosis demonstrate a large heterogeneity of clinical manifestations but are significant as they may be the presenting sign of disseminated disease. While usually confined to the lungs, extrapulmonary coccidioidomycosis can occur in about 1 in 200 patients, most commonly associated with immunocompromised status. Pregnancy is an …
Retrospective Review Of Adverse Events After Treatment Of Non-Melanoma Skin Cancer With Image-Guided Superficial Radiation Therapy, Marshall Hall, Henry Lim, Jason Pham, Alyssa Forsyth, Wenqin Du
Retrospective Review Of Adverse Events After Treatment Of Non-Melanoma Skin Cancer With Image-Guided Superficial Radiation Therapy, Marshall Hall, Henry Lim, Jason Pham, Alyssa Forsyth, Wenqin Du
North Texas GME Research Forum 2024
No abstract provided.
Geometric Favre-Racouchot Syndrome Following Image-Guided Superficial Radiation Therapy, Marshall Hall, Cecilia Nguyen, Christian Scheufele, Christopher M. Wong, Stephen E. Weis, Michael Carletti, Henry Lim
Geometric Favre-Racouchot Syndrome Following Image-Guided Superficial Radiation Therapy, Marshall Hall, Cecilia Nguyen, Christian Scheufele, Christopher M. Wong, Stephen E. Weis, Michael Carletti, Henry Lim
North Texas GME Research Forum 2024
Introduction: Favre-Racouchot Syndrome is a cutaneous disease characterized by nodules, cysts, and comedones located in sun-exposed areas of the face. It is most commonly found on the bilateral temporal and periorbital skin. Favre-Racouchot Syndrome is most associated with chronic sun exposure. It occurs more commonly in cigarette smokers. It has been rarely associated with radiation therapy. It has not been reported after image-guided superficial radiation therapy or in a geometric pattern. Case presentation: We present the first two recorded cases of Favre-Racouchot Syndrome occurring in the setting of image-guided superficial radiation therapy. Both patients presented with well-demarcated geometric plaques with …
Improving Lesion Diameter Reporting On Skin Biopsy Requisition Forms: A Quality Improvement Project, Christopher Wong, Christian Scheufele, Marshall Hall, Henry Lim, Daniel A. Nguyen, Stephen Weis, Michael Carletti, Dustin Wilkes
Improving Lesion Diameter Reporting On Skin Biopsy Requisition Forms: A Quality Improvement Project, Christopher Wong, Christian Scheufele, Marshall Hall, Henry Lim, Daniel A. Nguyen, Stephen Weis, Michael Carletti, Dustin Wilkes
North Texas GME Research Forum 2024
Background: Skin biopsy requisition forms (SBRFs) are the primary communication tool between dermatologists and dermatopathologists. Diameters of biopsied skin lesions are frequently omitted on SBRFs. This quality improvement project aimed to increase the rate of reporting diameters of neoplasms on SBRFs from an academic dermatology outpatient clinic to greater than 65% within three years. Methods: The Plan-Do-Study-Act model was utilized. An initial audit was performed for SBRFs of biopsies obtained between July 1, 2021, and February 4, 2022 (“Cycle 1”). On February 4, 2022, the authors discussed societal guidelines for lesion diameter reporting on SBRFs (“Intervention A”). Cycle 2 prospectively …
Impact Of Tiered Implementation Of Clinical Decision Support System For Acute Kidney Injury And Nephrotoxin Exposure In Cardiac Surgery Patients, Christopher M. Justice Ii
Impact Of Tiered Implementation Of Clinical Decision Support System For Acute Kidney Injury And Nephrotoxin Exposure In Cardiac Surgery Patients, Christopher M. Justice Ii
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background: Nephrotoxin exposure may worsen kidney injury and impair kidney recovery if continued in patients with acute kidney injury (AKI).
Objective: To determine if tiered implementation of a clinical decision support system (CDSS) would reduce nephrotoxin use in cardiac surgery patients with AKI.
Methods: We assessed patients admitted to the cardiac surgery intensive care unit at a tertiary care center from January 2020 to December 2021, and August 2022 to September 2023. A passive electronic AKI alert was activated in Jul 2020, followed by an electronic nephrotoxin alert in March 2023. In this alert, active nephrotoxic medication orders resulted in …
Successful Management Of Spontaneous Unilateral Twin Ectopic Pregnancy With Two-Step Dose Of Methotrexate, Lauren A. Forbes, Navya Nuthivana, Renee Morales
Successful Management Of Spontaneous Unilateral Twin Ectopic Pregnancy With Two-Step Dose Of Methotrexate, Lauren A. Forbes, Navya Nuthivana, Renee Morales
Department of Obstetrics & Gynecology Faculty Publications
The incidence of unilateral tubal twin pregnancy is 1/20,000–1/250,000 with about 100 reported cases. Four of the six cases that were medically managed were successful. A 24-year-old female presented to the emergency department (ED) with vaginal bleeding and abdominal cramping. She was hemodynamically stable without signs of an acute abdomen. Laboratory evaluation revealed she was pregnant with a serum beta-human chorionic gonadotropin (b-hCG) of 798 mIU/mL. Transvaginal ultrasound (TVUS) revealed a single left tubal pregnancy with a yolk sac. The patient elected medical management with body surface area (BSA)–based intramuscular (IM) methotrexate (MTX). On Day 4, the patient returned to …
Tim/Tam Receptors: A Potential Biomarker For Predicting Sensitivity To Zika Virus-Induced Oncolysis In Non-Small Cell Lung Cancers, Shankari Somasekar
Tim/Tam Receptors: A Potential Biomarker For Predicting Sensitivity To Zika Virus-Induced Oncolysis In Non-Small Cell Lung Cancers, Shankari Somasekar
Honors Undergraduate Theses
Non-small cell lung cancers (NSCLC) constitute 80-85% of lung cancers and are the leading cause of cancer-related deaths globally. The most common cause is prolonged smoking. Current treatment options for NSCLC include surgery, radiation, chemotherapy, targeted drug therapy, and immunotherapy. Although these medications are effective in the short term, patients often face issues of drug resistance and debilitating side effects with prolonged use. Currently, the use of Zika virus (ZIKV) is being researched as a possible alternative treatment for cancer, which minimizes side effects and the risk of drug resistance. TIM/TAM proteins are identified as the putative ZIKV receptors on …