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Articles 1 - 8 of 8
Full-Text Articles in Physiological Processes
Dynamics And Malleability Of Plant Dna Methylation During Abiotic Stresses, Niraj Lodhi, Rakesh Srivastava
Dynamics And Malleability Of Plant Dna Methylation During Abiotic Stresses, Niraj Lodhi, Rakesh Srivastava
Department of Pathology, Anatomy, and Cell Biology Faculty Papers
Epigenetic regulation, particularly DNA methylation, plays a crucial role in plant adaptation to environmental stresses by modulating gene expression without altering the underlying DNA sequence. In response to major abiotic stresses such as salinity, drought, heat, cold, and heavy metal toxicity, plants undergo dynamic changes in DNA methylation patterns. These modifications are orchestrated by DNA methyltransferases and demethylases with variations depending on plant species, genetic background, and ontogenic phase. DNA methylation affects the expression of key genes involved in cellular, physiological, and metabolic processes essential for stress tolerance. Furthermore, it contributes to the establishment of stress memory, which can be …
Worried Sick: Understanding The Implications Of Stress On A Physiological Level, Julia Saia
Worried Sick: Understanding The Implications Of Stress On A Physiological Level, Julia Saia
Senior Honors Theses
Stress is prevalent among many individuals in today’s society. A literature review was conducted to investigate the physiological effects of stress, including the biomarkers of stress and how these interact with various body systems. The stress response is a protective mechanism to prepare the body to adequately respond to a perceived threat. However, when this response is prolonged, it begins to have a maladaptive effect on the body and can cause more harm than good. This literature review sought to compile what is known regarding the general effects of chronic stress and its impact on the nervous, immune, digestive, and …
Evaluation Of Hippocampal Allostatic Load-Associated Factors In Animal Models Of Post-Traumatic Stress Disorder: Relevance To Human Ptsd, Dennis Parker Kelley
Evaluation Of Hippocampal Allostatic Load-Associated Factors In Animal Models Of Post-Traumatic Stress Disorder: Relevance To Human Ptsd, Dennis Parker Kelley
LSU Doctoral Dissertations
Post-traumatic stress disorder (PTSD) is associated with elevated allostatic load, nearly double the risk for metabolic syndrome, reduced hippocampal volume, and contextual memory processing deficits. Emerging evidence suggests that these stress effects may predispose individuals to the development of PTSD, and there is a known relationship between chronic stress and metabolic dysfunction. In this work, we utilized two rat models of PTSD to explore these connections. We used an acute predator odor stressor to investigate the relationship between PTSD-like behaviors and mitochondrial dysfunction in the hippocampus of rats, and we observed that conditioned place avoidance was associated with reduced mitochondrial …
Psychological Resilience In Student-Athletes During The Covid-19 Pandemic, Henley Lapid
Psychological Resilience In Student-Athletes During The Covid-19 Pandemic, Henley Lapid
Theses and Dissertations (Comprehensive)
The purpose of this qualitative study was to examine the psychological resilience process in student-athletes during the unique adverse context of the COVID-19 pandemic. The study sought to answer the following research questions guided by Fisher et al.’s (2019) heuristic framework: (1) What resilience mechanisms, (2) promoting factors, and (3) resilience outcomes were experienced by participants in their resilience demonstrations? and (4) How does the resilience process unfold over time across adverse contexts including the COVID-19 pandemic? Nine student-athletes from Wilfrid Laurier University were interviewed on their experiences demonstrating resilience within and outside of the pandemic. A thematic analysis (Braun …
The Relationship Of Divine Forgiveness, Victim Forgiveness, And Physical Health Mediated By Stress, Lemuel Josiah C. Ragasajo
The Relationship Of Divine Forgiveness, Victim Forgiveness, And Physical Health Mediated By Stress, Lemuel Josiah C. Ragasajo
Senior Honors Theses
Though there is increasing evidence to support a relationship between forgiveness and physical health, certain subcategories of forgiveness, namely victim and divine forgiveness, are relatively understudied. This study seeks to add to the body of forgiveness literature by examining how divine and victim forgiveness relate to one’s physical health, and whether that relationship is mediated by stress. Furthermore, a literature review is included to detail how stress, a potential mediating variable between forgiveness and physical health, affects physical health. The results of the study reveal that victim forgiveness positively predicts physical health, but is not mediated by stress. In contrast, …
Effects Of Heat Stress And Exercise On Shooting Performance, Patrick R. Lindecker
Effects Of Heat Stress And Exercise On Shooting Performance, Patrick R. Lindecker
Graduate Student Theses, Dissertations, & Professional Papers
Purpose: The purpose of this study was to evaluate the effects of exercise and acute heat stress on marksmanship performance measures of accuracy, precision, aim time, and distance travelled by the point of aim in trained US military veterans. Methods: Subjects (N=8) (height 184.1 ± 10.9 cm (SD), weight 92.1 ± 10.6 kg, 21.1 ± 8.9% body fat, VO2max 47.25 ± 7.36 mL/kg/min, age 26.8 ± 4.3 yrs.) completed one-hour of walking at 50% VO2max in a hot (35˚C, 30% maximal relative humidity) or cool (22˚C, 30% maximal relative humidity) environment. Core temperature, heart …
Persistent Stress-Induced Neuroplastic Changes In The Locus Coeruleus/Norepinephrine System, Olga Borodovitsyna, Neal Joshi, Daniel Chandler
Persistent Stress-Induced Neuroplastic Changes In The Locus Coeruleus/Norepinephrine System, Olga Borodovitsyna, Neal Joshi, Daniel Chandler
Rowan-Virtua School of Osteopathic Medicine Departmental Research
Neural plasticity plays a critical role in mediating short- and long-term brain responses to environmental stimuli. A major effector of plasticity throughout many regions of the brain is stress. Activation of the locus coeruleus (LC) is a critical step in mediating the neuroendocrine and behavioral limbs of the stress response. During stressor exposure, activation of the hypothalamic-pituitary-adrenal axis promotes release of corticotropin-releasing factor in LC, where its signaling promotes a number of physiological and cellular changes. While the acute effects of stress on LC physiology have been described, its long-term effects are less clear. This review will describe how stress …
Syndecan 4 Is Required For Endothelial Alignment In Flow And Atheroprotective Signaling, Nicolas Baeyens, Mary Jo Mulligan-Kehoe, Federico Corti, David D. Simon, Tyler D. Ross, John M. Rhodes, Thomas Z. Wang
Syndecan 4 Is Required For Endothelial Alignment In Flow And Atheroprotective Signaling, Nicolas Baeyens, Mary Jo Mulligan-Kehoe, Federico Corti, David D. Simon, Tyler D. Ross, John M. Rhodes, Thomas Z. Wang
Dartmouth Scholarship
Atherosclerotic plaque localization correlates with regions of disturbed flow in which endothelial cells (ECs) align poorly, whereas sustained laminar flow correlates with cell alignment in the direction of flow and resistance to atherosclerosis. We now report that in hypercholesterolemic mice, deletion of syndecan 4 (S4−/−) drastically increased atherosclerotic plaque burden with the appearance of plaque in normally resistant locations. Strikingly, ECs from the thoracic aortas of S4−/− mice were poorly aligned in the direction of the flow. Depletion of S4 in human umbilical vein endothelial cells (HUVECs) using shRNA also inhibited flow-induced alignment in vitro, which was rescued by re-expression …