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Full-Text Articles in Neurosciences

Hypercoagulable And Autoimmune Factors In Patients With Moyamoya Syndrome, Justin F. Fraser, Min Jian Hou Ma, Christopher Mclouth, Laura Whitnel, Jessica Lasslo, David Dornbos Iii, Jill Roberts May 2025

Hypercoagulable And Autoimmune Factors In Patients With Moyamoya Syndrome, Justin F. Fraser, Min Jian Hou Ma, Christopher Mclouth, Laura Whitnel, Jessica Lasslo, David Dornbos Iii, Jill Roberts

Neuroscience Research Data

Moyamoya is a progressive cerebrovascular condition leading to stenosis of the internal carotid arteries (ICA) and formation of abnormal vasculature at the base of the brain. Patients ultimately suffer from ischemic and/or hemorrhagic stroke. In Kentucky, patients often present with comorbidities, which classifies them as having moyamoya syndrome (MMS). In this prospective observational study, we measured coagulable- and autoimmune-related factors in MMS subjects to identify possible therapeutic targets and help inform clinical care. Venous blood samples were collected from adult subjects diagnosed with MMS and analyzed by the UK Healthcare Clinical Laboratory. Blood samples, demographics, and medical records were obtained …


Heart Rate Variability Following Blood Flow Restriction Resistance Exercise And Traditional Resistance Exercise In Trained Men And Women, Michael R. Perlet, Lauren I. Mendonça, Peter A. Hosick, Nicholas Licameli, Evan L. Matthews Jan 2025

Heart Rate Variability Following Blood Flow Restriction Resistance Exercise And Traditional Resistance Exercise In Trained Men And Women, Michael R. Perlet, Lauren I. Mendonça, Peter A. Hosick, Nicholas Licameli, Evan L. Matthews

Research Data

Autonomic nervous system responses are attenuated following blood flow restriction (BFR) resistance exercise vs traditional resistance exercise (TRE) in men, but women’s responses are unknown. The purpose of this investigation is to compare the effects of a single BFR vs TRE session on HRV. Thirty-nine adults (M=20, W=19, age: 23±4yrs, body mass: 72.3±13.2kg, height: 169±9cm) participated in the study. Barbell back squat 1 repetition maximum (1RM) testing was performed followed by two randomized and counterbalanced exercise visits ≥48hrs apart (BFR: 4 sets, 30-15-15-15 repetitions, 30% 1RM, 60s rest; TRE: 4 sets x 10 repetitions, 70% 1RM, 60s rest). Pre- and …