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Musculoskeletal, Neural, and Ocular Physiology Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
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- Anatomy (2)
- Medical Neurobiology (2)
- Musculoskeletal System (2)
- Psychology (2)
- Social and Behavioral Sciences (2)
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- Behavioral Neurobiology (1)
- Biological Phenomena, Cell Phenomena, and Immunity (1)
- Cognition and Perception (1)
- Geriatric Nursing (1)
- Human Factors Psychology (1)
- Immunity (1)
- Immunology and Infectious Disease (1)
- Life Sciences (1)
- Medical Cell Biology (1)
- Medical Immunology (1)
- Medical Specialties (1)
- Neuroscience and Neurobiology (1)
- Nursing (1)
- Ophthalmology (1)
- Physiological Processes (1)
- Keyword
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- Hindlimb unloading (2)
- Spaceflight (2)
- Animal models (1)
- Bedrest (1)
- Bone loss (1)
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- Color misperception (1)
- Cross-species comparison (1)
- Drosophila melanogaster (1)
- HPA axis (1)
- Immune system (1)
- Microgravity (1)
- Microgravity model (1)
- Model organism (1)
- Muscle (1)
- Muscle atrophy (1)
- Railway lights (1)
- Red railway traffic signals (1)
- Social isolation (1)
- Spaceflight Gravity (1)
- Train signals (1)
- Transcriptomics (1)
- Publication Type
Articles 1 - 5 of 5
Full-Text Articles in Musculoskeletal, Neural, and Ocular Physiology
Artificial Gravity Partially Protects Space-Induced Neurological Deficits In Drosophila Melanogaster, Amber M. Paul, Siddhita D. Mhatre, Janani Iyer, Juli Petereit, Roberta M. Dolling-Boreham
Artificial Gravity Partially Protects Space-Induced Neurological Deficits In Drosophila Melanogaster, Amber M. Paul, Siddhita D. Mhatre, Janani Iyer, Juli Petereit, Roberta M. Dolling-Boreham
Publications
Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in Drosophila aboard the International Space Station in response to spaceflight microgravity (SFmg) and artificially simulated Earth gravity (SF1g) via inflight centrifugation as a countermeasure. While inflight behavioral analyses of SFmg exhibit increased activity, postflight analysis displays significant climbing defects, highlighting the sensitivity of behavior to altered gravity. Multiomics analysis shows alterations in metabolic, oxidative stress and synaptic transmission pathways in both SFmg and SF1g; however, neurological changes immediately postflight, including neuronal loss, glial cell count alterations, oxidative …
Mammalian And Invertebrate Models As Complementary Tools For Gaining Mechanistic Insight On Muscle Responses To Spaceflight, Amber M. Paul, Thomas Cahill, Henry Cope, Joseph J. Bass, Eliah G. Overbey, Rachel Gilbert
Mammalian And Invertebrate Models As Complementary Tools For Gaining Mechanistic Insight On Muscle Responses To Spaceflight, Amber M. Paul, Thomas Cahill, Henry Cope, Joseph J. Bass, Eliah G. Overbey, Rachel Gilbert
Publications
Bioinformatics approaches have proven useful in understanding biological responses to spaceflight. Spaceflight experiments remain resource intensive and rare. One outstanding issue is how to maximize scientific output from a limited number of omics datasets from traditional animal models including nematodes, fruit fly, and rodents. The utility of omics data from invertebrate models in anticipating mammalian responses to spaceflight has not been fully explored. Hence, we performed comparative analyses of transcriptomes of soleus and extensor digitorum longus (EDL) in mice that underwent 37 days of spaceflight. Results indicate shared stress responses and altered circadian rhythm. EDL showed more robust growth signals …
Influence Of Social Isolation During Prolonged Simulated Weightlessness By Hindlimb Unloading, Candice G.T. Tahimic, Amber M. Paul, Ann-Sofie Schreurs, Samantha M. Torres, Linda Rubinstein, Sonette Steczina
Influence Of Social Isolation During Prolonged Simulated Weightlessness By Hindlimb Unloading, Candice G.T. Tahimic, Amber M. Paul, Ann-Sofie Schreurs, Samantha M. Torres, Linda Rubinstein, Sonette Steczina
Publications
The hindlimb unloading (HU) model has been used extensively to simulate the cephalad fluid shift and musculoskeletal disuse observed in spaceflight with its application expanding to study immune, cardiovascular and central nervous system responses, among others. Most HU studies are performed with singly housed animals, although social isolation also can substantially impact behavior and physiology, and therefore may confound HU experimental results. Other HU variants that allow for paired housing have been developed although no systematic assessment has been made to understand the effects of social isolation on HU outcomes. Hence, we aimed to determine the contribution of social isolation …
Musculoskeletal Disorders In The Nursing Profession: A Case Study, Kaitlin A. Kee-Dayton
Musculoskeletal Disorders In The Nursing Profession: A Case Study, Kaitlin A. Kee-Dayton
Human Factors and Applied Psychology Student Conference
Musculoskeletal Disorders in the Nursing Profession: A Case Study
Kaitlin Kee-Dayton
Beth Blickensderfer, Ph.D.
Embry-Riddle Aeronautical University
Daytona Beach, FL
This ergonomics assessment focused on a female Licensed Practical Nurse (LPN) and her life inside and outside of her job. In particular, this case study assessed how working as a nurse may affect the human body in terms of Musculoskeletal Disorders (MSDs). The researcher first conducted an in-depth interview with the nurse about her workplace layout, typical daily work schedule, work habits, physical challenges, MSD injuries she has sustained, and the workplace environment/organizational culture. Next, the researcher conducted three MSD …
When Red Lights Look Yellow, Joanne M. Wood, David A. Atchison, Alex Chaparro
When Red Lights Look Yellow, Joanne M. Wood, David A. Atchison, Alex Chaparro
Publications
Purpose. Red signals are typically used to signify danger. This study was conducted to investigate a situation identified by train drivers in which red signals appear yellow when viewed at long distances (∼900 m) through progressive-addition lenses.
Methods. A laboratory study was conducted to investigate the effects of defocus, target size, ambient illumination, and surround characteristics on the extent of the color misperception of train signals by nine visually normal participants. The data from the laboratory study were validated in a field study by measuring the amounts of defocus and the distances at which the misperception of the color of …