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Full-Text Articles in Medical Molecular Biology
Comparative Analysis Of The Distribution Of Segmented Filamentous Bacteria In Humans, Mice And Chickens, Yeshi Yin, Yu Wang, Liying Zhu, Wei Liu, Ningbo Liao, Mizu Jiang, Baoli Zhu, Hongwei Yu, Charlie Xiang, Xin Wang
Comparative Analysis Of The Distribution Of Segmented Filamentous Bacteria In Humans, Mice And Chickens, Yeshi Yin, Yu Wang, Liying Zhu, Wei Liu, Ningbo Liao, Mizu Jiang, Baoli Zhu, Hongwei Yu, Charlie Xiang, Xin Wang
Hongwei Yu
Segmented filamentous bacteria (SFB) are indigenous gut commensal bacteria. They are commonly detected in the gastrointestinal tracts of both vertebrates and invertebrates. Despite the significant role they have in the modulation of the development of host immune systems, little information exists regarding the presence of SFB in humans. The aim of this study was to investigate the distribution and diversity of SFB in humans and to determine their phylogenetic relationships with their hosts. Gut contents from 251 humans, 92 mice and 72 chickens were collected for bacterial genomic DNA extraction and subjected to SFB 16S rRNA-specific PCR detection. The results …