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Genetic Structures Commons

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Full-Text Articles in Genetic Structures

The Role Of Nogo-A During Development Of The Chick Central Nervous System, Shelly A. Caltharp Aug 2007

The Role Of Nogo-A During Development Of The Chick Central Nervous System, Shelly A. Caltharp

Loma Linda University Electronic Theses, Dissertations & Projects

Nogo-A is a potent inhibitor of axon regeneration that is expressed by myelin forming oligodendrocytes of the adult central nervous system (CNS). However, neuronal expression of Nogo-A during development suggests an additional role. Little is known about the putative functions of Nogo-A during embryonic development. To examine its potential role we isolated and analyzed the Nogo-A sequence in the chick, we localized its mRNA expression pattern and cell-specific distribution during key phases of cortical development, and studied regulation of its expression during phases that showed promise of function based on expression patterns.

Our results revealed five previously undescribed Nogo-A specific …


Unlv Magazine, Gian Galassi, Vicki Smith, Erin O'Donnell, Lisa Shawcroft, Angela Sablan, Maria Phelan, Beth English, Eric Leake Jul 2007

Unlv Magazine, Gian Galassi, Vicki Smith, Erin O'Donnell, Lisa Shawcroft, Angela Sablan, Maria Phelan, Beth English, Eric Leake

UNLV Magazine

No abstract provided.


Physical Characteristics Of An Individual: The Identification Of Biomarkers For Biological Age Determination, Michelle Alvarez Jan 2007

Physical Characteristics Of An Individual: The Identification Of Biomarkers For Biological Age Determination, Michelle Alvarez

Electronic Theses and Dissertations

It is now a matter of routine for the forensic scientist to obtain the genetic profile of an individual from DNA recovered from a biological stain deposited at a crime scene. Potential contributors of the stain must either be known to investigators (i.e. a developed suspect) or the questioned profile must be searched against a database of DNA profiles such as those maintained in the CODIS National DNA database. However, in those instances where there is no developed suspect and no match is obtained after interrogation of appropriate DNA databases, the DNA profile per se presently provides no meaningful information …