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Full-Text Articles in Digestive, Oral, and Skin Physiology
Dietary Fibre On Cell Proliferation In Large Bowel Mucosal Crypts Near Or Away From Lymphoid Nodules And On Mineral Bioavailability, Ivan Cameron, W. Hardman, D. Heitman, J. Carter
Dietary Fibre On Cell Proliferation In Large Bowel Mucosal Crypts Near Or Away From Lymphoid Nodules And On Mineral Bioavailability, Ivan Cameron, W. Hardman, D. Heitman, J. Carter
Elaine Hardman Ph.D.
The effect of consumption for 24 weeks of different amounts (0%, 5% or 10% w/w) of fermentable (pectin and guar gum) or nonfermentable (cellulose and lignin) dietary fibres on cell proliferation and other parameters in large bowel mucosal crypts was studied in rats. In all 12 dietary groups, the crypts located over the distal aggregate of lymphoid nodules (ALN) had more colchicine arrested metaphase figures per midaxial crypt section (MC) and a longer crypt column height than crypts located three to four cm away from this ALN. These differences are attributed to the tropic in¯uence of nodular cells in the …
Numerical Distribution Of Lymphoid Nodules In The Human Sigmoid Colon, Rectosigmoidal Junction, Rectum, And Anal Canal, Ivan L. Cameron, James E. Kent, Ron Philo, Christopher J. Barnes, W. Elaine Hardman
Numerical Distribution Of Lymphoid Nodules In The Human Sigmoid Colon, Rectosigmoidal Junction, Rectum, And Anal Canal, Ivan L. Cameron, James E. Kent, Ron Philo, Christopher J. Barnes, W. Elaine Hardman
Elaine Hardman Ph.D.
There is little information on the numerical distribution of lymphoid nodules (LN) in distal segments of the human large bowel. A novel approach was therefore developed to assess the number of LN in the sigmoid colon, the rectosigmoid segment, the rectum, and the anal canal in humans. The distal large bowel from five cadavers was selected for quantitative study. The number of LN was scored macroscopically from the proximal sigmoid colon to the distal anal canal. A numerical distribution, previously unreported, consisting of two circular bands of LN was observed in each of the five cadavers. One band was located …