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Articles 1 - 5 of 5
Full-Text Articles in Digestive, Oral, and Skin Physiology
Nuclear Receptor Expression And Characterization Of The Major Retinoic Acid Target Gene In Melanoma, Linda L. Eastham
Nuclear Receptor Expression And Characterization Of The Major Retinoic Acid Target Gene In Melanoma, Linda L. Eastham
Linda L. Eastham
Malignant melanoma is the primary cause of death from all diseases arising from the skin and it is one of the most resistant tumors to standard treatment options. The increasing incidence of melanoma and its poor prognosis makes the understanding of melanoma cell biology very important. Melanoma progression is a complex, multi-step process, and the molecular events leading to melanoma tumor cell proliferation and invasion still need further examination. This study is focused on measuring the expression and activity of two specific genes and their protein counterparts that are altered during melanoma progression. It also examines the mechanism through which …
Dietary Fibre On Cell Proliferation In Large Bowel Mucosal Crypts Near Or Away From Lymphoid Nodules And On Mineral Bioavailability, Ivan Cameron, W. Hardman, D. Heitman, J. Carter
Dietary Fibre On Cell Proliferation In Large Bowel Mucosal Crypts Near Or Away From Lymphoid Nodules And On Mineral Bioavailability, Ivan Cameron, W. Hardman, D. Heitman, J. Carter
Elaine Hardman Ph.D.
The effect of consumption for 24 weeks of different amounts (0%, 5% or 10% w/w) of fermentable (pectin and guar gum) or nonfermentable (cellulose and lignin) dietary fibres on cell proliferation and other parameters in large bowel mucosal crypts was studied in rats. In all 12 dietary groups, the crypts located over the distal aggregate of lymphoid nodules (ALN) had more colchicine arrested metaphase figures per midaxial crypt section (MC) and a longer crypt column height than crypts located three to four cm away from this ALN. These differences are attributed to the tropic in¯uence of nodular cells in the …
Numerical Distribution Of Lymphoid Nodules In The Human Sigmoid Colon, Rectosigmoidal Junction, Rectum, And Anal Canal, Ivan L. Cameron, James E. Kent, Ron Philo, Christopher J. Barnes, W. Elaine Hardman
Numerical Distribution Of Lymphoid Nodules In The Human Sigmoid Colon, Rectosigmoidal Junction, Rectum, And Anal Canal, Ivan L. Cameron, James E. Kent, Ron Philo, Christopher J. Barnes, W. Elaine Hardman
Elaine Hardman Ph.D.
There is little information on the numerical distribution of lymphoid nodules (LN) in distal segments of the human large bowel. A novel approach was therefore developed to assess the number of LN in the sigmoid colon, the rectosigmoid segment, the rectum, and the anal canal in humans. The distal large bowel from five cadavers was selected for quantitative study. The number of LN was scored macroscopically from the proximal sigmoid colon to the distal anal canal. A numerical distribution, previously unreported, consisting of two circular bands of LN was observed in each of the five cadavers. One band was located …
Racemization Of Amino Acids In Teeth For The Determination Of Age, Andrea Lee Toll
Racemization Of Amino Acids In Teeth For The Determination Of Age, Andrea Lee Toll
Masters Theses & Specialist Projects
Instrumental to forensic investigations is the ability to identify unknown human remains providing key evidence to criminal cases, resolution to missing persons, and assistance in mass or natural disasters. Identification of remains in an effort to determine age is an area of forensics that has received considerable attention. Traditional methods in age determination such as morphology are often biased, antiquated, and frequently result in a large margin of error. Conversely, the emergence of new forensic techniques provide promise to reduce the margin of error in determining age. One such technique has focused on relating the extent of amino acid racemization …
Nuclear Receptor Expression And Characterization Of The Major Retinoic Acid Target Gene In Melanoma, Linda L. Eastham
Nuclear Receptor Expression And Characterization Of The Major Retinoic Acid Target Gene In Melanoma, Linda L. Eastham
Theses, Dissertations and Capstones
Malignant melanoma is the primary cause of death from all diseases arising from the skin and it is one of the most resistant tumors to standard treatment options. The increasing incidence of melanoma and its poor prognosis makes the understanding of melanoma cell biology very important. Melanoma progression is a complex, multi-step process, and the molecular events leading to melanoma tumor cell proliferation and invasion still need further examination. This study is focused on measuring the expression and activity of two specific genes and their protein counterparts that are altered during melanoma progression. It also examines the mechanism through which …