Chemical and Pharmacologic Phenomena Commons^™

Taraxacum Officinale Effect On The Reduction Of Pro-Inflammatory Cytokines Il-6 And Tnf-A, Bailee Bad Heart Bull, Kat Kraemer, Kira Mccallum, Ruth Teeple

Undergraduate Research Symposium 2025

Dandelion (Taraxacum officinale) is a ubiquitous plant found in every continent except Antarctica. Despite its condemnation as a weed, it has been used for centuries in traditional European, Indian, and Chinese herbal medicine for its purported digestive and diuretic properties. Its leaves contain antioxidants and bioactive compounds like taraxasterol, which have been reported to reduce reactive oxygen species production and inhibit nitric oxide production. There have been claims that taraxasterol can reduce inflammation by reducing the production of pro-inflammatory cytokines; a cytokine is a small protein released by immune cells that helps regulate inflammation, immune responses, and cell communication. Our …

Investigating The Effects Of Palmitoylation In Ovcar3 Cells, Bethany Knopp, Emu Suzuki

Undergraduate Research Symposium 2025

Ovarian cancer is a disease characterized by the abnormal growth of cells in the ovaries often due to mutations in our DNA. Because ovarian cancer is typically diagnosed at advanced stages, the survival rate is less than 40% over a five-year period. One significant influence of this cancer is palmitoylation - a post- translational modification in which fatty acid chains are added to specific cysteine residues in proteins. This modification alters protein localization, stability, and function. When dysregulated, as seen in ovarian cancer, palmitoylation can promote irregular cell growth, mutations, and ultimately cancer. However, the role of palmitoylation in cancer …

Reminiscence Therapy For Prevention Of Post-Stroke Anxiety And Depression In Adults, Carly Porter

Master of Science in Physician Assistant Studies Capstone Presentations (Center City)

Introduction

Anxiety and depression are prevalent after a stroke.^1,2 Peer support is a non-pharmacologic intervention utilized to manage post-stroke anxiety and depression with inconsistent results.³ Reminiscence therapy is an intervention that has been studied in the dementia population but is a relatively new intervention for the stroke population and has the potential to impact the psychological care provided to stroke patients.⁴