Medical Sciences Commons^™

Exploring The Developmental Effects Of Antidepressants In Caenorhabditis Elegans, Alexandra Van Stone

Annual Research Symposium

It is so important to explore the potential side effects of antidepressants especially if these side effects could lead to a future detriment to an individual’s financial and social well-being. A better understanding of these side effects in regards to human developmental issues is imperative considering issues related to mental health and depression affect a large percentage of the population. In this study, we tested if Caenorhabditis (C.) elegans could be a potential model organism to predict possible side effects associated with select antidepressants. Their developmental problems potentially encountered upon drug treatment may be encountered in humans.

Soft Tissue Secrets: A Comparative Analysis Of Facial Soft Tissue Thickness In Skeletal Class Ii Versus Class I Malocclusions, Jacob Thomas

Annual Research Symposium

This study aimed to measure facial soft tissue thicknesses in adults with skeletal class II malocclusion and compare them to individuals with skeletal class I relationships. The outcomes intended to provide clinicians with data to enhance treatment strategies for facial reconstruction and esthetics.

Ergonomics And Musculoskeletal Disorders Among Dental Students And Practitioners, Ardra Nair S Intern, Sudeep C. B Professor And Head Of The Department Public Health Dentistry

Annual Research Symposium

study to determine the prevalence of musculoskeletal disorders among dental students and dental practitioners in Calicut district.

Challenges In Diagnosing Hepatic Epithelioid Hemangioendothelioma: A Case Series, Aratara Nutcharoen, Elliott Beard, Anupa Thirmiya, Omar Taher, Jacob Adams, Mark Mortensen, John Pelham

Annual Research Symposium

Challenges in Diagnosing Hepatic Epithelioid Hemangioendothelioma

Treatment Of Craniofacial Problems With Stem Cells In Dentistry, Melanie Katz, Mahsa Sadri, George Dresser, Noor Sulaiman, Amir Mohajeri, Connor Schwartz, Man Hung

Annual Research Symposium

To focus on regenerative capabilities and self-renewal abilities of stem cells on bone and tissue regeneration

Pharmacognosy And Trichomoniasis: A Scoping Review Protocol, Claire Hartwell, Melanie Arslanian, Brad Haubrich

Annual Research Symposium

Trichomoniasis, also called “trich”, is the most common non-viral sexually transmitted infection (STI). Its etiological agent is the protozoan parasite Trichomonas vaginalis, against which first-line antiparasitics usually work. However, resistance is on the rise. Trich has traditionally been considered a nuisance infection, with many (particularly AMAB patients) being asymptomatic. But research in recent years has begun to unravel correlations of trichomonal infections with a myriad of comorbitidies, including infertility, cancers, the pathogenesis of AIDS, and pelvic inflammatory disease (PID). Between the rise of drug resistance and the incidence of these comorbidities, new treatments are needed. In this work, we are …

Behind The Spine: Investigating The Role Of Cervical Posture And Range Of Motion On Mental Health, Layla Risdon, Luis Alvarez, Cassidy Byers, Davis Byers, Louis Michelon, Tallon Muhlestein, Natalie Tate, Garret Vincent, Christina Small, David Sant, Kurt Alexander, Kyle Bills

Annual Research Symposium

This research explores the correlation between abnormal forward head posture, cervical range of motion, and psychiatric disorders. Specifically, the study examines the relationships between the loss of cervical lordosis and anxiety, depression, and ADHD. Previous studies have demonstrated the beneficial effect of manipulative therapy on forward head posture and provided a link between postural alignment and cognitive function. This investigation aims to build on existing literature and enhance understanding of how loss of cervical lordosis impacts cervical and overall range of motion as well as its potential association with psychiatric conditions.

Effectiveness Of Omt On Cardiovascular Function: A Systematic Review., Sarah Legrand

Annual Research Symposium

Vascular disease is responsible for the top two causes of death worldwide. Osteopathic manipulative treatment (OMT) is currently utilized mostly for alleviating musculoskeletal symptoms, but it has shown promise as a non-invasive approach to improve cardiovascular function. There is currently no consensus that OMT can have short-term or long-term effects on cardiovascular function. The utility of OMT in maintaining cardiovascular system health is an emerging area of practice. The purpose of this systematic review project is to investigate the short-term and long-term effects of OMT on cardiovascular function and its regulators in the nervous and endocrine systems.

Porcelain Fused To Zirconia Wing Bridge: A Clinical Trial, Gerald Greenan

Annual Research Symposium

This study evaluated the durability and retention of nine porcelain fused to zirconia wing bridges with the addition of counter sunk holes in the wings. Prior to this clinical trial, preliminary in-vitro testing of bridges with porcelain fused zirconia was performed. The nine bridges were then fabricated for the replacement of missing anterior teeth.

Long Non-Coding Rna As A Potential Diagnostic Tool In Coronary Artery Diseases - A Systematic Review, Arthi Sri A.S, Vishnu Priya Veeraraghavan

Annual Research Symposium

POSTER - SYSTEMATIC REVIEW - LONG NON CODING RNAS AS DIAGNOSTIC MARKER FOR CAD

Influence Of Orthodontic Treatment On Changes In The Maxillary Sinus Dimensions, Eiji Tanaka Dds, Phd, Hiroshi Yamada Dds, Phd, Masaaki Higashino Md, Phd, Saya Suetake Dds, Susumu Abe Dds, Phd

Annual Research Symposium

This study aimed to investigate the correlation of craniofacial morphology with maxillary sinus morphology and to evaluate whether orthodontic treatment facilitates maxillary sinus enlargement in adults.

Correlation Between Salivary Levels And Tissue Expression Status Of Her2 In Breast Cancer Patients - A Cross-Sectional Study, Arthi Sri A.S, Massillamani F, Vinothkumar Thilla Sekar

Annual Research Symposium

The study aims to investigate if soluble salivary human epidermal growth factor receptor-2 (HER2) would play a role in the diagnosis of breast cancer patients and also to find out the influence of demographic and hormonal factors on the salivary HER2 levels in breast cancer.

Fit Evaluation Of Soft Milled Zirconia And Cocr By Microcomputed Tomography, Elie Daou

Annual Research Symposium

Statement of problem. The absolute marginal fit of CAD-CAM presintered fixed partial dentures has been poorly documented. Purpose. The purpose of this in vitro study was to evaluate the marginal fit of presintered cobalt-chromium (Co-Cr) and zirconia 3-unit fixed partial dentures by using X-ray microcomputed tomography (mCT).

Material and methods. A metal model was prepared from a typodont to receive fixed partial dentures (N=12). The maxillary first premolar and first molar were prepared with a circumferential 1.2-mm chamfer and 2-mm occlusal reduction. The dies were scanned and assigned to 1 of 2 groups to receive the prostheses made of presintered …

Smile Miles Away: Navigating The Future Of Teledentistry, Farhad Jafeen J, Prem Blaisie Rajula, Pl Ravishankar, Shivani Senthilkumar

Annual Research Symposium

Teledentistry is a combination of telecommunications and dentistry involving the exchange of clinical information and images over remote distances for dental consultation and treatment planning. Teledentists are capable of improving access to oral healthcare, increasing the provision of oral health care and reducing its costs. The disparities in oral health care between rural and urban areas could also be eliminated. This article analyses the origin, rationale, scope, basis and requirements of teledentistry in conjunction with current evidence available in the literature. Ethical and legal issues relating to teledentistry, as well as the future of this alternative and innovative way of …

Investigating Optimal Laboratory Growth Conditions Of Gracilibacillus Halotolerans In Media Supplemented With Salt, Isaac Young

Annual Research Symposium

As interest continues to grow in the field of persister cells and their morphology, there arises an ever-evolving desire to further understand specific strains of bacteria that exemplify the qualities of seemingly anomalous survival regardless of anti-bacterial treatment. In the case of the Gracilibacillus halotolerans, a halotolerant extremophile extracted from the Great Salt Lake with known persistent characteristics, uncovering its optimal growth conditions was essential for future investigations. Identifying the optimal salinity for the growth of G. halotolerans will allow us to standardize our growth methods, uncover several mechanisms of saline tolerance, and add to future investigations of persistence with …

Analysis Of Adolescent Malnutrition On Oral Health: A Systematic Review, Amy Blazejewski

Annual Research Symposium

This review aimed to explore the relationship between malnutrition and oral health in adolescents.

A literature search in PubMed, Dentistry & Oral Sciences Source, Scopus, and Web of Science was conducted on September 13th, 2023. Peer-reviewed articles written in English and published from 2013 containing information on the negative impact of adolescent malnutrition on oral health were considered eligible for review. From the 594 studies obtained from the literature search, 88 studies were included.

Evidence Of Prostate Cancer Progression In Transgender Women After Hormone Replacement Therapy - Scoping Review Protocol, Emily Nelson

Annual Research Symposium

This scoping review aims to determine the extent and quality of evidence regarding prostate cancer progression outcomes in transgender women who have undergone hormone replacement therapy. Notably, transgender females undergoing hormone replacement therapy as a component of the gender affirmation treatment commonly have their prostate, rendering them vulnerable to developing prostate cancer. There is no current agreement about the likelihood of transgender women developing prostate cancer or the impact of hormone replacement therapy on oncogenic molecular pathways. Unfortunately, due to a lack of scientific data and inadequate trust and awareness in the medical community, transgender women are often not provided …

Comparative Analysis Of Denture Cleanser Effects On Surface Roughness:Traditional Vs. 3d-Printed Resin Bases – A Systematic Review, Taroniar Sevathas, Shilpa Bhandi, Kamran H. Awan, Frank W. Licari, Shankargouda Patil

Annual Research Symposium

This systematic review aimed to assess the effect of denture cleansers on the surface roughness of 3D-printed denture base resins in comparison to conventionally manufactured counterparts.

Evaluating The Oral Health-Related Quality Of Life Among Dental Patients In South India - A Descriptive Study, Dheekshitha P K, Sudeep C B Dr., Sunil P M Dr., Suji M Dr.

Annual Research Symposium

This study aims to evaluate the oral health-related quality of life among dental patients in South India.

Relationship Between Periodontal Disease And Coronary Heart Disease: A Bibliometric Analysis, Xiaowen Bo, Wenpeng Song

Annual Research Symposium

Periodontal disease (PD) and coronary heart disease (CHD) are both prevalent diseases worldwide and cause patients physical and mental suffering and a global burden. Recent studies have suggested a link between PD and CHD, but there is less research in this field from the perspective of bibliometrics. This study aimed to quantitatively analyze the literature on PD and CHD to summarize intellectual bases, research hotspots, and emerging trends and pave the way for future research.

Deciphering Psilocybin: Cytotoxicity, Anti-Inflammatory Effects, And Mechanistic Insights, Salma Laabi, Claire Lemmon, Callie Vogel, Mariana Chacon, Victor M. Jimenez

Annual Research Symposium

A decade of clinical research indicates psilocybin's effectiveness in treating various neuropsychiatric disorders, such as depression and substance abuse. The correlation between increased pro-inflammatory cytokines and the severity of neuropsychiatric symptoms, along with the known anti-inflammatory potential of some psychedelics, suggests an immunomodulatory role for psilocybin. This study aims to understand psilocybin's mechanism of action by investigating the cytotoxic and immunomodulatory effects of psilocybin and psilocin on both resting and LPS-activated RAW 264.7 murine macrophages.

Role Of Mumio In Periodontal Wound Healing–An In Vitro Study On Human Pdl Cells, Jagadish Hosmani, Abdullah Alqarni, Abdullah Alqahtani, Nasser Alhamid

Annual Research Symposium

Mumio, used in ancient medicine for almost 4000 years, is the gold standard of traditional medicine. Mumio, a tar-like compound made from rock dissolved minerals and degraded organic matter, takes a century to form. Dibenzo-alpha-pyrones, humic acid, and fulvic acid are important in Mumio, which includes 60–80% humus, benzoic acid, fatty acids, ichthyol, ellagic acid, resin, triterpenes, sterol, aromatic carboxylic acids, bioactive 3,4-benzokoumarins, amino acids, phenol Active chemicals improve Mumio's antioxidant effects. Despite its anti-ulcerogenic, anti-inflammatory, antioxidant, immunomodulatory, memory-enhancing, and anxiolytic characteristics, mumio has been studied rarely on oral tissues. The present study examined the cytotoxic, antioxidant, anti-inflammatory, and reparative …

Efficacy Of Concentrated Growth Factor Membrane Versus Collagen Membrane In Treating Gingival Recession, Shazneen Kandawalla

Annual Research Symposium

Creating a beautiful smile has always been a cornerstone of dental practice. Gingival recession, characterized by a downward shift of the gum line, causing uneven gum margins and an unattractive appearance.

The Vestibular Incision Subperiosteal Tunnel Access (VISTA) technique, introduced by Zadeh in 2011, offers an innovative solution for root coverage. Concentrated Growth Factor Membrane (CGF) further enhances dental repair.

Spatial Analysis Of Maxillary Central Incisors In Relation To The Nasopalatine Canal And Surrounding Alveolar Bone, Harnoor Dhillon

Annual Research Symposium

The use of mini-implants in orthodontics has enabled greater retraction of incisors than previously achievable. This change underscores the need to understand how incisors relate to the alveolar bone and nasopalatine canal. The varying labiolingual inclination of incisors during orthodontic treatments may influence these anatomical relationships. Our study aimed to assess the spatial relationship between maxillary central incisors and the surrounding alveolar bone and nasopalatine canal.

Implementation Of Best Practice When Collecting Blood Cultures In The Emergency Department (Ed), Parker Grossman

Annual Research Symposium

The purpose of this study is to compare blood culture contamination rates in the ED before and after educational in-services on best practice.

Overlooked Dental Disease In Cbct Imaging And The Impact Of Oral Radiologist Interpretation, Jared Fausnaught

Annual Research Symposium

This study aims to underscore the necessity for a comprehensive interpretation of Cone Beam Computed Tomography (CBCT) volume images obtained by dentists. The research demonstrates and quantifies potentially overlooked dental pathology, categorizing incidental findings into three groups: 1) requiring some form of treatment or follow-up, 2) necessitating follow-up (monitoring) only, and 3) demanding no further treatment or follow-up.

Photodynamic Therapy Effects In The Treatment Of Residual Periodontal Pockets, Kade Janes

Annual Research Symposium

This systematic review examined the adjunctive effect of photodynamic therapy to treat residual pockets.

Impact Of Non-Surgical Periodontal Treatment On Salivary Hif-1Α In Gingivitis & Periodontitis Patients, Srijanani S

Annual Research Symposium

To estimate and compare the level of salivary HIF-1α in periodontally & systemically healthy volunteers, generalized chronic gingivitis & periodontitis patients before and after non-surgical periodontal treatment.

Euglycemic Diabetic Ketoacidosis Secondary To Sodium Glucose 2 Transport Inhibitor: A Case Report, Alexis Duevel, Edward Ramirez

Annual Research Symposium

The purpose of this case report is to highlight the emergence of a rare adverse drug reaction (ADR), euglycemic diabetic ketoacidosis (EDKA), associated with the use of sodium glucose transport 2 (SGLT2) inhibitors.EDKA is a rare and often misdiagnosed condition, due to the absence of hyperglycemia, but represents a life-threatening emergency. We present a unique case of a 35-year-old female patient with a past medical history of diabetes and recent diagnosis of Hashimoto’s thyroiditis. The primary objective is to provide valuable insights and education to the medical community regarding this infrequent yet significant complication. Ultimately, the goal is to enhance …

Detection And Relative Quantitation Of Changes In Gene Expression Of Hippo Proteins In Doxorubicin-Exposed Human Cells By Rt-Qpcr, Lillian Fleisher, Tricia Domingo, Christopher So, Stephen Lee

Annual Research Symposium

The HIPPO signaling pathway plays a key role in cell proliferation and tumor suppression. It consists of serine/threonine kinase cascades, including MST1/2, LATS1/2, YAP, and TAZ. When the HIPPO pathway is activated, gene expression is altered. Dysfunction of the activity of this cascade may contribute to cancer development and chemoresistance. FAT4 is an intracellular protein that may regulate the HIPPO signaling. The purpose of this study is to determine the relative changes of mRNA of the HIPPO pathway members and FAT4 in doxorubicin-treated and vehicle-treated in vitro cell lines.