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Articles 301 - 306 of 306

Full-Text Articles in Medical Sciences

Passive Cation Transport In Reversibly Sickling Deer Red Blood Cells, Norma C. Adragna, Peter K. Lauf Dec 1988

Passive Cation Transport In Reversibly Sickling Deer Red Blood Cells, Norma C. Adragna, Peter K. Lauf

Pharmacology and Toxicology Faculty Publications

No abstract provided.


Kinetics Of Na/Li Exchange In High-K (Hk) And Low-K (Lk) Sheep Red Cells (Src), K. H. Ryu, Norma C. Adragna, D. Bradley, Peter K. Lauf Jan 1987

Kinetics Of Na/Li Exchange In High-K (Hk) And Low-K (Lk) Sheep Red Cells (Src), K. H. Ryu, Norma C. Adragna, D. Bradley, Peter K. Lauf

Pharmacology and Toxicology Faculty Publications

No abstract provided.


Optimal Isolation Conditions For Ion-Transport Studies In Pig Aortic Endothelial-Cells, Norma C. Adragna Jan 1987

Optimal Isolation Conditions For Ion-Transport Studies In Pig Aortic Endothelial-Cells, Norma C. Adragna

Pharmacology and Toxicology Faculty Publications

No abstract provided.


Electrophysiology Of Flounder Intestinal Mucosa. I. Conductance Properties Ofthe Cellular And Paracellular Pathways, Dan R. Halm, Edward J. Krasny Jr., Raymond A. Frizzell Jun 1985

Electrophysiology Of Flounder Intestinal Mucosa. I. Conductance Properties Ofthe Cellular And Paracellular Pathways, Dan R. Halm, Edward J. Krasny Jr., Raymond A. Frizzell

Neuroscience, Cell Biology & Physiology Faculty Publications

We evaluated the conductances for ion flow across the cellular and paracellular pathways of flounder intestine using microelectrode techniques and ion-replacement studies. Apical membrane conductance properties are dominated by the presence of Ba-sensitive K channels. An elevated mucosal solution K concentration, [K]m, depolarized the apical membrane potential (ψa) and, at [K]m less than 40 mM, the K dependence of ψa was abolished by 1-2 mM mucosal Ba. The basolateral membrane displayed Cl conductance behavior, as evidenced by depolarization of the basolateral membrane potential (ψb) with reduced serosal Cl concentrations, [Cl]s. …


Electrophysiology Of Flounder Intestinal Mucosa. Ii. Relation Of The Electrical Potential Profile To Coupled Nacl Absorption, Dan R. Halm, Edward J. Krasny Jr., Raymond A. Frizzell Jun 1985

Electrophysiology Of Flounder Intestinal Mucosa. Ii. Relation Of The Electrical Potential Profile To Coupled Nacl Absorption, Dan R. Halm, Edward J. Krasny Jr., Raymond A. Frizzell

Neuroscience, Cell Biology & Physiology Faculty Publications

We characterized the hyperpolarization of the electrical potential profile of flounder intestinal cells that accompanies inhibition of NaCl cotransport. Several observations indicate that hyperpolarization of ψa and ψb (Δψa,b) results from inhibition of NaCl entry across the apical membrane: (a) the response was elicited by replacement of mucosal solution Cl or Na by nontransported ions, and (b) mucosal bumetanide or serosal cGMP, inhibitors of NaCl influx, elicited Δψa,b and decreased the transepithelial potential (ψt) in parallel. Regardless of initial values, ψa and ψb approached the equilibrium potential for K (EK …


Metabolism In Preimplantation Mouse Embryos, Harry M. Weitlauf, Gary L. Nieder Jul 1984

Metabolism In Preimplantation Mouse Embryos, Harry M. Weitlauf, Gary L. Nieder

Neuroscience, Cell Biology & Physiology Faculty Publications

The ability of preimplantation mouse embryos to utilize glucose oxidatively is controlled, in part at least, at the level of glycolysis. Various experimental observations are reviewed that indicate the regulatory mechanism in delayed implanting blastocysts involves the classic negative allosteric feedback of high levels of ATP on phosphofructokinase while the situation in 2-cell embryos appears to be more complicated. That is, in addition to the usual negative effect of ATP and citrate on phosphofructokinase, there appears to be a modification of hexokinase that prevents phosphorylation of adequate amounts of glucose and results in low levels of fructose-6-phosphate at the 2-cell …