Medical Sciences Commons^™

Investigating The Impact Of Tirzepatide Treatment On Alcohol And Cigarette Consumption, Yvannia Gray, Benjamin Latey, Hayden Mcaffee, Karissa Mccown, Seth Maki, Victoria Nguyen, Andrew Payne

Annual Research Symposium

No abstract provided.

Transcranial Magnetic Stimulation As A Treatment Modality For Functional Bowel Disorder And Irritable Bowel Syndrome And Possible Correlations With The Gut-Brain Axis: A Review, Lauren Draper, Devin Pfister, Ethan Zaugg

Annual Research Symposium

Functional Bowel Disorders (FBD), including Irritable Bowel Syndrome (IBS), are highly prevalent gastrointestinal conditions classified as Disorders of Gut-Brain Interactions (DGBIs) under the Rome IV criteria. These conditions, marked by abdominal pain, altered bowel habits, and significant psychological comorbidities, present substantial challenges in both diagnosis and treatment. Conventional therapies primarily target gut-centric mechanisms but often yield limited efficacy, underscoring the need for approaches that account for the complex interplay of the gut-brain axis in DGBI pathophysiology.

Investigating The Effects Of Resveratrol On Opioid-Induced Hyperalgesia, Bryana Cox, Thien Do, Ashlyn Hughes, Zane Kingsbury, Keara Leroy, Andrew J. Payne

Annual Research Symposium

Opioid-induced hyperalgesia (OIH) is an adverse effect of chronic opioid therapy, characterized by increased sensitivity to pain. This study will seek to determine if using resveratrol supplementation as an indirect enhancer to increase the expression of the KCC2 membrane transporter can alleviate the symptoms of OIH in human subjects.

Unraveling Physiologic Mechanisms In Passive And Active Mechanoreceptor Stimulation, Halah Khan, Braden Ashcraft

Annual Research Symposium

No abstract provided.

A Morphological Investigation Of Alcohol-Induced Persister Formation, Isaac Young, Victor Jimenez

Annual Research Symposium

No abstract provided.

Identifying Breathing, Swallowing, And Speech Biosignatures In Parkinson’S Disease Patients With Wearable Devices, Amanda Brandaris, Katherine Shishido, Rohaan Manzoor, Ethan Hampton, Karthik Jasty, Kelvin Guo, Anna Fish, Spencer Peterson, Ulrike H. Mitchell Phd, Phillip Sechtem Phd, Ccc-Slp, Paula Johnson Phd, Anton E. Bowden Phd, Miriam Cortez-Cooper Pt, Phd, Pamela I. Barney Msrt, Rrt, Ae-C, Nps, John A. Kriak Pharmd

Annual Research Symposium

No abstract provided.

A Galleria Mellonella Study: Protective Effects Of Sulforaphane On Immune Function In Binge Alcohol Exposure, Robert Kento Darby, Braydon Black, Vincent Tran, Dallen James, Scott Quimby

Annual Research Symposium

Alcohol is associated with increased mortality and morbidity. Pulmonary infections with opportunistic pathogens can occur in healthy humans; however, hazardous alcohol exposure like binge alcohol intoxication (≥ 0.08% BAC) is a major risk factor. We’ve previously investigated the efficacy of Sulforaphane (SFN) prophylaxis in protecting human and murine alveolar macrophage function against opportunistic infections when exposed to binge alcohol conditions in vitro. However, an in vivo model investigating SFN and hazardous alcohol exposure in the context of infection is not well understood. The aim of this study is to 1) establish a G. mellonella larvae model by determining the LD50 …

Educating Medical Students In Sleep, Diet, And Exercise To Determine Effects On Their Treatment Plan Development For Future Patients, Paul Jackson, Wyatt Edgekoski, Kaleb Gustavsen, Andrew Payne

Annual Research Symposium

No abstract provided.

Venous Thromboembolism Prophylaxis In Orthopedic Surgery: A Narrative Review, Jacob Lahti, Sarah Gallitto, Thomas C. Varkey

Annual Research Symposium

This poster highlights current and updated guidelines for chemical and mechanical prophylaxis for venous thromboembolism in patients undergoing major and minor orthopedic surgery. Existing and new potential therapies were reviewed, as well as an analysis into the lack of high-quality risk-prediction score calculators to improve personalization of prophylaxis regimens. Alongside a summary of existing and potential new prophylaxis protocols, a call to action to improve validity of said risk score calculators so as to improve patient outcomes and personalized medicine is made.

Assessment Of Condylar Morphology In Various Facial Types-Cbct Study, Dr.Shruti Patil

Annual Research Symposium

Mandibular condyle being part of the TMJ complex, its volume and shape play a pivotal role in treatment stability and outcomes in orthodontic and orthognathic patients over long term periods. Different loading patterns would result in different morphology of the TMJ. The association with different facial types and understanding the relationship between condylar position, morphology and jaw base divergence is limited. This study’s objective is to assess the condylar structure which includes condylar height, width and height of the fossa in different jaw base divergences.

A cross-sectional study was conducted in which 90 patients undergoing Orthodontic treatment were selected and …

A Systematic Review: Mirror Neurons & Schizophrenia, Yashesvi Sharma, Surajit Dey

Annual Research Symposium

This research project establishes a link between Mirror Neuron System (MNS) activity and this information's implications in treating and understanding schizophrenia, specifically, schizophrenic patients with negative symptoms.

Angiofibroma Of Soft Tissue: A Case Report, Mehruba Alam, Jake Robins

Annual Research Symposium

Differentiation between benign angiofibromas of soft tissue and malignant sarcomas.

The accurate diagnosis of this tumor is essential to prevent additional unnecessary treatments and/or surgeries. This can be achieved by proper genetic testing for the presence of markers including the NCOA2 fusion gene, CD34, α-SMA, and epithelial membrane antigen. Genetic testing is an essential component of accurate diagnosis as the appearance of these lesions can mimic other, more harmful neoplasms. Immunohistochemical analysis frequently shows the AHRR-NCOA2 driver mutation which is thought to be associated with t(5;8)(p15;q13), also commonly found in AFSTs. In combination, these immunohistochemical findings allow for accurate diagnosis …

Chronic Intractable Migraine: A Case Study, Natalie Tate, Luis Alvarez, Cassidy Byers, Davis Elm, Louis Michelon, Tallon Muhlestein, Layla Risdon, Garret Vincent, Christina A. Small, David W. Sant, Kyle B. Bills, Kurt M. Alexander

Annual Research Symposium

No abstract provided.

Revolutionizing Denture Excellence: An Invigorating In-Vitro Exploration Of Organic Products In Prosthetic Rehabilitation, Nighila Ravindran, Sneha Joseph, Aswani Surya K

Annual Research Symposium

The denture base comes into contact with diverse substances in the oral cavity, acting as a reservoir for microorganisms like corynebacterium, streptococcus, lactobacillus, and candida. This colonization elevates the risk of complications such as denture stomatitis and candidiasis. Commercial denture cleaners have explored the use of natural ingredients, less commonly employed but offering various advantages. These ingredients aim to mitigate the potential issues associated with microbial colonization on denture surfaces, contributing to improved oral hygiene for denture wearers. The exploration of natural elements reflects a nuanced approach to denture care, considering both efficacy and less conventional alternatives.

Investigating Racial And Ethnic Healthcare Disparities In Screenable Ob/Gyn-Related Cancers, Lara Laughrey

Annual Research Symposium

This is a scoping review of peer-reviewed literature addressing healthcare inequity based on race and ethnicity with a specific focus on Ob/Gyn-related management and treatment of screenable cancers.

Assessment Of Emotional Intelligence Among Students In Dental College, Gowri Nandana S Final Year Student, Sudeep C. B Professor And Head Of The Department Of Public Health Dentistry

Annual Research Symposium

Over an extended period, the examination of intelligence predominantly centered on the adaptive deployment of cognitive abilities. In more recent times, scholars such as Gardner (1983) and Sternberg (1988) have proposed comprehensive frameworks for comprehending intelligence. Pioneering the concept of "emotional intelligence," Salovey and Mayer (1990) posited that emotional intelligence encompasses three distinct categories of adaptive capabilities: the evaluation and expression of emotions, the regulation of emotions, and the utilization of emotions in problem-solving. The objective is to evaluate emotional intelligence among dental students across various educational institutions.

Exploring Glucose Dysregulation In Migraine: Insights From Continuous Glucose Monitoring, Jackson Nielsen, Matthew Jennings, Alexander Kim, Pooja Chemiti, Stephanie Chavez, Alfred Amendolara, John Dougherty Jr., Kyle Reavely, Amanda Page, Brandon J. Burger, Christina A. Small, David W. Sant, John A. Kriak, Kyle B. Bills

Annual Research Symposium

Despite being associated with hypoglycemia for nearly a century, a definitive relationship between migraines and glucose dysregulation remains elusive. Accumulating evidence suggests that migraines are in part due to a metabolic mismatch between cerebral demand and available energy. Research analyzing plasma glucose levels and migraine activity may further elucidate this interface between metabolic dysregulation and migraine pathophysiology and may potentially open avenues for therapeutic interventions targeting holistic metabolism for migraine management.

Quality Of Life In Orthodontics, Claudia Eisenhuth, Gabriel Eisenhuth, Connor Schwartz, Amir Mohajeri, Man Hung, Tiffany Nelson, Ryann Glenn

Annual Research Symposium

Orthodontic treatment goes beyond mere cosmetic enhancement; it significantly impacts various aspects of an individual's quality of life. Beyond the physical benefits of improved oral function and prevention of dental issues, orthodontics also yields profound psychological benefits. Aligned teeth enhance self-confidence, reduce social anxiety, and contribute to better relationships and professional opportunities. Moreover, addressing dental concerns through orthodontic treatment reduces psychological distress and promotes overall happiness and satisfaction. Real-life case studies vividly illustrate the transformative effects of orthodontic interventions, emphasizing the importance of considering quality of life outcomes in dental care.

Exercise Blocks Ethanol-Induced Kappa Opioid Receptor Sensitization In Nucleus Accumbens And Ventral Tegmental Area, Brandon J. Burger, Alexander Kim, Bridger Gunter, Jude Emego, Laura Minor, James Brundage, Benjamin Williams, Christina A. Small, Jordan Yorgason, Scott Steffenson, Kyle B. Bills

Annual Research Symposium

Exercise has been increasingly used as an adjunctive therapy in the treatment of alcohol use disorder (AUD). Despite this, the mechanism by which it influences the mesolimbic circuitry changes underlying alcohol addiction is not well understood. Previous studies have shown alcohol dependence to lead to upregulation of the Dynorphin-Kappa Opioid Receptor (KOR) system, making it a potential target for therapeutics. Thus, gaining a better understanding of these pathways will help develop evidence-based guidelines for integrating exercise into therapies for the treatment of AUD.

Dissecting The Impact Of Medicinal Plants On Systemic Diseases, Karen Ayetiwa

Annual Research Symposium

For this literature review, a range of databases were used such as Google Search, PubMed, and Web of Science (mentioned all the ones you used). The search strategy used was a combination of terms such as "medicinal plant compounds," "plant polysaccharides on metabolic diseases," "effects of berberine on diabetes mellitus," " and "effects of medicinal plants on Alzheimer's." Articles chosen for review were published between 2020 and 2022, and only studies in the English language were considered. The majority of the selected studies were devised to observe and analyze the effects of medicinal plant compounds on various systemic diseases. Medicinal …

De Novo Microdeletion Spanning Ywhae And Crk In An Individual With Intellectual Disability And Stunted Growth, Eden E. Pope, John A. Kriak, Kyle B. Bills, David W. Sant

Annual Research Symposium

In this report, we present a case of a 20-year-old female with congenital intellectual disability, stunted growth, and hypothyroidism. Competitive genetic hybridization (CHG) revealed a loss of a portion of 17p13.3 at least 195 Kb in size, not present in either parent. This area of chromosome 17 is associated with Miller-Dieker Syndrome (MDS) and Isolated Lissencephaly Sequence (ILS), but these conditions are related predominantly to PAFAH1B1, which is not included in the patient’s deletion.

Investigating The Interplay Between Glucose Regulation, Neural Activity, And Motivation: A Novel Approach Utilizing Vibration Stimulation, Blake D. Harris, Patrick Tanner Brain, Alessandra Maisie Rivera, Tiffany Nguyen, James Barber, Amar Paul, John Dougherty Jr., Matthew Jennings, Bridger Gunter, David W. Sant, Christina A. Small, Scott Steffenson, Kyle B. Bills

Annual Research Symposium

This research explores the intricate relationship between glucose regulation, neural activity, and motivation in key brain regions, including the hypothalamus, basal ganglia, ventral tegmental area (VTA), and nucleus accumbens (NA). We aim to unravel the potential relationship of these factors on dopamine (DA) release and the broader implications for mental health, glucose regulation, well-being, and overall health. Our innovative approach involves using a chair that causes heterodyned whole-body vibration designed to stimulate DA release from the VTA and NA, areas associated with motivation and rewards.

Shed Stem Cells: Antibacterial And Immunomodulatory Insights, Manju R Prof

Annual Research Symposium

SHED- Stem cells extracted from exfoliated teeth - resource for Stem Cell based regenerative therapy; multipotent in nature

We examined explored how SHED affects the growth of common oral bacteria, Streptococcus mutans and Enterococcus faecalis, and their role in regulating immune response.

Trichomonas Vaginalis Infection In Emergency Department Patients, Owen Christian Schubert

Annual Research Symposium

Trichomonas vaginalis (TV) is a common sexually transmitted infection (STI) that affects around 2.3 million women and 1.4 million men in the United States. TV infection in females can cause vaginal discharge, dysuria and abdominal pain and can be complicated by pelvic inflammatory disease, infertility, cervical neoplasia and increased transmission rates of other STIs. In males, TV can cause urethral discharge and dysuria, but is often asymptomatic and therefore not often studied. We seek to determine the rates of TV infection among male and female patients presenting to EDs for STI evaluation in the Las Vegas metropolitan area, and compare …

Exploring The Interconnected Role Of The Oral Microbiome And Periodontal Disease In The Development And Progression Of Oral Squamous Cell Carcinoma, Malak Al-Regib, Claudia M. Tellez Freitas

Annual Research Symposium

This comprehensive review explores the complex linkage among the oral microbiome, periodontal disease, and the onset and progression of oral squamous cell carcinoma (OSCC).

Non-Hodgkin's Lymphoma Of The Oral Cavity - A Rare Entity, Anita J. Florence Dr, Karpagaselvi Sanjai Prof & Dr

Annual Research Symposium

Non-Hodgkin’s lymphoma (NHL) is a subtype of lymphoma with two-thirds of the cases presenting as lymph node enlargement. The remaining one third of NHL cases has been reported in the extra nodal sites, including the gastro-intestinal tract, Waldeyer’s ring, bone, skin and brain. Intraoral NHL is uncommon and may affect either the jaw bones or occur within the soft tissues of the oral cavity. Here we report an unusual case of non-Hodgkin’s lymphoma in a 54-year-old male patient who presented with a growth from the right lower molar extraction socket with pus discharge.

Modified Zero-Gravity Chair In The Management Of Pain And Anxiety With Emphasis On Pre And Post Anesthesia For Surgical Procedures, Alexander Tisdale, Kinsley Batson, Zachary Jamous, Isabella Termini, Kyle Mooday, Matt Cohn, Jackson Justice

Annual Research Symposium

The purpose of this research is the integration of a zero-gravity chair with planar vibration as a non-pharmaceutical approach to preoperative anxiety and postoperative pain management. The treatment plan involves preoperative familiarization with the chair's vibrational patterns and postoperative use for pain relief. Integration of this approach holds promise in reshaping postoperative care paradigms, advocating for personalized, holistic interventions to enhance patient well-being and mitigate opioid-related risks.

Success And Challenges Of Infrazygomatic Crest Implants In Orthodontics, Gauri Gill

Annual Research Symposium

Poster on success rates of mini implants used in the infrazygomatic region for orthodontic anchorage , as well as the factors that influence the success of the mini implant placed in IZC region.

Dna Extraction Method Development For Ocular Tissues, Conrad K. Ashby, Michael C. Trapnell, Walker C. Kay, Jonathon C. Reynolds, Noah R. Schultz, Brandon J. Burger, Christina A. Small, John A. Kriak, Kyle B. Bills, David W. Sant

Annual Research Symposium

Purpose: DNA extraction kits are traditionally developed to work with liquid tissues such as blood, saliva, and swabs, but some have been proposed to work with solid tissues. Somatic variation in cancers can be important for tumor subtyping and treatment guidance, including ocular tumors. Additionally, epigenetic marks such as 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are tissue-specific and change in disease states, particularly evident in diabetic retinopathy and age-related macular degeneration. Commercial DNA extraction kits are available from several vendors, but the various kits have different strengths and weaknesses, and the removal of PCR inhibitors will vary with each kit. This …

Non-Traditional Presenting Grade Ii Brain Meningioma: A Case Study, Alessandra M. Rivera, Garret Phillips, Serin Baker, Michael Trapnell, Conrad Ashby, Jacob Hill, Prina Patel, Alexander Ruiz, Elden Jenkins, Johan A. Kriak, Kyle B. Bills, Voicu S. Ciobanu, Tipsuda Bahri, David W. Sant

Annual Research Symposium

Meningioma is a relatively common form of cancer, occurring in approximately 97 out of 100,000 individuals. Although it arises from the meninges surrounding the central nervous system (CNS) rather than from neurons, it is classified with CNS tumors due to overlapping symptoms caused by compression of nerves and vessels in the head. Extracranial metastasis is rare, at less than 1%, and correlates with reduced survival rates.