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Clinical Research in Practice: The Journal of Team Hippocrates

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Full-Text Articles in Medical Education

Mechanical Pleurodesis Is Not A Contraindication To Lung Transplantation, Alexa Thibodeau Feb 2018

Mechanical Pleurodesis Is Not A Contraindication To Lung Transplantation, Alexa Thibodeau

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Shigemura N, Bhama J, Gries CJ, et al. Lung transplantation in patients with prior cardiothoracic surgical procedures. American Journal of Transplantation. 2012;12(5):1249-1255. doi: 10.1111/j.1600-6143.2011.03946.x


Closure Of Patent Foramen Ovale Or Medical Therapy Alone Are Both Appropriate Choices For Preventing Recurrent Cryptogenic Strokes, Kevin Juan Zhang Feb 2018

Closure Of Patent Foramen Ovale Or Medical Therapy Alone Are Both Appropriate Choices For Preventing Recurrent Cryptogenic Strokes, Kevin Juan Zhang

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Carroll JD, Saver JL, Thaler DE, et al. Closure of Patent Foramen Ovale versus Medical Therapy after Cryptogenic Stroke. N Engl J Med, 2013;368(12):1092-1100. doi:10.1056/nejmoa1301440.


Multiple Doctors, Different Recommendations For Multiloculated Pyogenic Hepatic Abscesses, Eric Gr Kim Feb 2018

Multiple Doctors, Different Recommendations For Multiloculated Pyogenic Hepatic Abscesses, Eric Gr Kim

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Hope WW, Vrochides DV, Newcomb WL, Mayo-Smith WW, Iannitti DA. Optimal treatment of hepatic abscess. The American Surgeon. 2008 Feb;74(2):178-82. doi: 10.1016/j.jamcollsurg.2010.03.004


Cognitive Behavioral Therapy For Patients With Psychogenic Non-Epileptic Seizures, Andrew Brown Feb 2018

Cognitive Behavioral Therapy For Patients With Psychogenic Non-Epileptic Seizures, Andrew Brown

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Goldstein L., Chalder T., et al. Cognitive-behavioral therapy for psychogenic non-epileptic seizures: A pilot RCT. Neurology. 2010;74(24):1986-1994. doi: 10.1212/WNL.0b013e3181e39658


From The Editor: Demonstrating Implementation Of Clinical Research Into Clinical Practice, James Peter Meza Feb 2018

From The Editor: Demonstrating Implementation Of Clinical Research Into Clinical Practice, James Peter Meza

Clinical Research in Practice: The Journal of Team Hippocrates

The editor stresses that learning to apply scientific research to clinical decision-making is not a formulaic endeavor.


Remote Video Monitoring Is Another Example Of “Dying On The Machine” For Critically Ill Patients, Noveera A. Mirza, Joshua A. Christian, Christopher M. Lajeunesse Sep 2017

Remote Video Monitoring Is Another Example Of “Dying On The Machine” For Critically Ill Patients, Noveera A. Mirza, Joshua A. Christian, Christopher M. Lajeunesse

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Hardin SR, Dienemann J, Rudisill P, Mills KK. Inpatient fall prevention: use of in-room webcams. J Patient Saf. 2013 Mar;9(1):29-35. doi: 10.1097/PTS.0b013e3182753e4f


Patient-Controlled Analgesia Improves Pain Control In A Vaso-Occlusive Crisis In Sickle Cell Patients, Rujul H. Parikh Sep 2017

Patient-Controlled Analgesia Improves Pain Control In A Vaso-Occlusive Crisis In Sickle Cell Patients, Rujul H. Parikh

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of van Beers EJ, van Tuijn CF, Nieuwkerk PT, Friederich PW, Vranken JH, Biemond BJ. Patient-controlled analgesia versus continuous infusion of morphine during vaso-occlusive crisis in sickle cell disease, a randomized controlled trial. Am J Hematol. 2007;82(11):955-60. doi: 10.1002/ajh.20944


Hydroxyurea Lowers The Frequency Of Sickle Cell Vaso-Occlusive Crises, Corey S. Macrander Sep 2017

Hydroxyurea Lowers The Frequency Of Sickle Cell Vaso-Occlusive Crises, Corey S. Macrander

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Charache S, Terrin ML, Moore RD, et al. Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. N Engl J Med 1995;(332):1317-1322 doi: 10.1056/nejm199505183322001


Clopidogrel Alone Is Safer Than Clopidogrel And Aspirin For Secondary Prevention Of Acute Ischemic Stroke., Bradford J. Woelke, Daniel Angell Do, Katherine Litow Md Aug 2017

Clopidogrel Alone Is Safer Than Clopidogrel And Aspirin For Secondary Prevention Of Acute Ischemic Stroke., Bradford J. Woelke, Daniel Angell Do, Katherine Litow Md

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Diener HC, Bogousslavsky J, Brass LM, et al. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet. 2004;364(9431):331-337. doi: 10.1016/s0140-6736(04)16721-4


Quality? Safety? Stop Being Naïve., Rana K. Zaban Do, Steven Istephan, Jonathan Serman Md Aug 2017

Quality? Safety? Stop Being Naïve., Rana K. Zaban Do, Steven Istephan, Jonathan Serman Md

Clinical Research in Practice: The Journal of Team Hippocrates

The first day of our inpatient medicine rotation, the Emergency Department (ED) admitted a patient to a general medical floor without notifying our rounding team. We used the institution’s system improvement tracking software to draw attention to communication breakdown in the interest of patient safety. This piece illustrates how there is a prominent hierarchy in medicine; it is inherent to the framework of the way in which hospitals function. A discussion ensues with our attending physician supervisor on our patient medicine service. During this discussion, we ponder whether it is possible to impact quality and safety from our position as …


Treating Diabetic Ketoacidosis With Subcutaneous Insulin?, Marlene Aziza Azar Aug 2017

Treating Diabetic Ketoacidosis With Subcutaneous Insulin?, Marlene Aziza Azar

Clinical Research in Practice: The Journal of Team Hippocrates

The author examines the evidence for treating diabetic ketoacidosis with subcutaneous insulin vs IV insulin.


Reframing Outcome Measures For Thrombolytics In Acute Ischemic Stroke, Brandon Baker, Charles W. Kropf, Nicholus Yee, James Peter Meza Aug 2017

Reframing Outcome Measures For Thrombolytics In Acute Ischemic Stroke, Brandon Baker, Charles W. Kropf, Nicholus Yee, James Peter Meza

Clinical Research in Practice: The Journal of Team Hippocrates

An informed consent conversation examining relevant research and discussing the potential benefits and harms of thrombolytic therapy in acute stroke.


It Is Not Necessary To Use Both An Ivc Filter And Anticoagulation Therapy For Severe Pulmonary Embolism, Radhika Sharma Aug 2017

It Is Not Necessary To Use Both An Ivc Filter And Anticoagulation Therapy For Severe Pulmonary Embolism, Radhika Sharma

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Mismetti P, Laporte S, Pellerin O, et al. Effect of a retrievable inferior vena cava filter plus anticoagulation vs anticoagulation alone on risk of recurrent pulmonary embolism: a randomized clinical trial. JAMA. 2015;313(16):1627–1635. doi: 10.1001/jama.2015.3780


Compared To Maximal Current Management Standards, Oscillating Positive Expiratory Pressure Devices Have Not Been Shown To Improve Clinically Relevant Outcomes In Copd Patients With Acute Exacerbation, Daniel P. Noack, Gaybriel Newton Aug 2017

Compared To Maximal Current Management Standards, Oscillating Positive Expiratory Pressure Devices Have Not Been Shown To Improve Clinically Relevant Outcomes In Copd Patients With Acute Exacerbation, Daniel P. Noack, Gaybriel Newton

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Ambrosino N, Callegari G, Galloni C, Brega S, Pinna G. Clinical evaluation of oscillating positive expiratory pressure for enhancing expectoration in diseases other than cystic fibrosis. Monaldi Arch Chest Dis. 1995;50(4):269-275.


Anticoagulation Increases Survival In Patients With Idiopathic Pulmonary Arterial Hypertension, Marvin L. Kajy Aug 2017

Anticoagulation Increases Survival In Patients With Idiopathic Pulmonary Arterial Hypertension, Marvin L. Kajy

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Olsson KM, Delcroix M, Ghofrani HA, et al. Anticoagulation and survival in pulmonary arterial hypertension: Results from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA). Circulation, 2014;129(1):57-65. doi: 10.1161/CIRCULATIONAHA.113.004526


From The Editor: Context Creates Meaning For Evidence, James Peter Meza Aug 2017

From The Editor: Context Creates Meaning For Evidence, James Peter Meza

Clinical Research in Practice: The Journal of Team Hippocrates

Introducing "Informed Consent" manuscripts and an expanded remit for the Journal.


Low Molecular-Weight Heparin Is Better Than Warfarin For Prevention Of Recurrent Venous Thromboembolism In Cancer Patients, Sarah Choi Apr 2017

Low Molecular-Weight Heparin Is Better Than Warfarin For Prevention Of Recurrent Venous Thromboembolism In Cancer Patients, Sarah Choi

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Lee AYY, Levin MN, Bake RI, et al. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med. 2003;349:146-153. doi: 10.1056/NEJMoa025313


The Ethics Of Offering Futile Treatment, Rebekah L. Eddy, Viktoria Krajnc, Lauren Smith Jan 2017

The Ethics Of Offering Futile Treatment, Rebekah L. Eddy, Viktoria Krajnc, Lauren Smith

Clinical Research in Practice: The Journal of Team Hippocrates

It important to acknowledge our own emotional biases and be cognizant of how we present evidence-based options to patients and their families, so that they may provide truly informed consent.


Stem Cell Therapy For End Stage Copd: A Cautionary Tale Of Direct-To-Consumer Advertising, Blake J. Arthurs, Scott Yaekle Jan 2017

Stem Cell Therapy For End Stage Copd: A Cautionary Tale Of Direct-To-Consumer Advertising, Blake J. Arthurs, Scott Yaekle

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Weiss DJ, Casaburi R, Flannery R, LeRoux-Williams M, Tashkin DP. A placebo-controlled, randomized trial of mesenchymal stem cells in COPD. Chest. 2013;143(6):1590-1598. doi: 10.1378/chest.12-2094


It Is Reasonable To Recommended Intrapleural Alteplase For Loculated Pleural Effusions, Tricia Fernandez Jan 2017

It Is Reasonable To Recommended Intrapleural Alteplase For Loculated Pleural Effusions, Tricia Fernandez

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Thommi G, Shehan J, Robison K, Christensen M, Backemeyer L, McLeay M. A double blind randomized cross over trial comparing rate of decortication and efficacy of intrapleural instillation of alteplase vs placebo in patients with empyemas and complicated parapneumonic effusions. Respir Med. 2012;17(2):716-723. doi: 10.1016/j.rmed.2012.02.005


Combination Octreotide, Midodrine, And Albumin May Improve Survival In Patients With Hepatorenal Syndrome, But The Evidence Is Weak, Jacob Szafranski Jan 2017

Combination Octreotide, Midodrine, And Albumin May Improve Survival In Patients With Hepatorenal Syndrome, But The Evidence Is Weak, Jacob Szafranski

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Skagen C, Einstein M, Lucey MR, Said A. Combination treatment with octreotide, midodrine, and albumin improves survival in patients with type 1 and type 2 hepatorenal syndrome. J Clin Gastroenterol. 2009 Aug;43(7):680-5. doi: 10.1097/MCG.0b013e318188947c


We Have No Real Evidence Related To Anticoagulation Plus Aspirin For Stroke Prevention In Atrial Fibrillation, Yuxiang Wang Jan 2017

We Have No Real Evidence Related To Anticoagulation Plus Aspirin For Stroke Prevention In Atrial Fibrillation, Yuxiang Wang

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Flaker GC, Gruber M, Connolly SJ, et al. Risks and benefits of combining aspirin with anticoagulant therapy in patients with atrial fibrillation: an exploratory analysis of stroke prevention using an oral thrombin inhibitor in atrial fibrillation (SPORTIF) trials. Am Heart J. 2006;152:967-973. doi: 10.1016/j.ahj.2006.06.024


Manage Terminal Ileum Diverticulitis Comparably To Diverticulitis Elsewhere, James Yip Jan 2017

Manage Terminal Ileum Diverticulitis Comparably To Diverticulitis Elsewhere, James Yip

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Park HC, Lee BH. The management of terminal ileum diverticulitis. Am Surg. 2009 Dec;75(12):1199-202.


From The Editor, James Peter Meza Jan 2017

From The Editor, James Peter Meza

Clinical Research in Practice: The Journal of Team Hippocrates

With this issue of the Journal, we expand types of submissions to include generalizable knowledge in the form of brief reports and original research.


Educating Clinician Scientists Once Again—A Societal Need, James Peter Meza Nov 2016

Educating Clinician Scientists Once Again—A Societal Need, James Peter Meza

Clinical Research in Practice: The Journal of Team Hippocrates

The Faculty Editor advocates for the training of clinician scientists again, using the body of clinical research as the laboratory.


Earth Suit, Bowhee Gwak, Young Park Oct 2016

Earth Suit, Bowhee Gwak, Young Park

Clinical Research in Practice: The Journal of Team Hippocrates

The authors reflect on an experience learning at the feet of a spirited patient.


Letter To The Editor: Restarting Warfarin After A Gastrointestinal Bleed, Lauren Smith Sep 2016

Letter To The Editor: Restarting Warfarin After A Gastrointestinal Bleed, Lauren Smith

Clinical Research in Practice: The Journal of Team Hippocrates

This letter addresses the dilemma of restarting anticoagulation after recent gastrointestinal bleeding.


There Is A Trend Favoring Vancomycin Vs. Metronidazole In Treating Severe C. Difficile Infection, Dean D. Fouchia Sep 2016

There Is A Trend Favoring Vancomycin Vs. Metronidazole In Treating Severe C. Difficile Infection, Dean D. Fouchia

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Johnson S, Louie TJ, Gerding DN, et al. Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: results from two multinational, randomized, controlled trials. Clin Infect Dis. 2014;59(3):345-354. doi: 10.1093/cid/ciu313


Critical Appraisal Is A Skill That Takes Practice: Our Patients Are Counting On Us, Dorothy Bourdet Sep 2016

Critical Appraisal Is A Skill That Takes Practice: Our Patients Are Counting On Us, Dorothy Bourdet

Clinical Research in Practice: The Journal of Team Hippocrates

A fumbling attempt at critical analysis in support of a clinical decision crystallizes the author's understanding that skillful analysis of research is crucial to good practice.


Early Haart Should Be Used For Treatment-Naive Hiv Patients With Pneumocystis Pneumonia, Maxwell L. Winkler Aug 2016

Early Haart Should Be Used For Treatment-Naive Hiv Patients With Pneumocystis Pneumonia, Maxwell L. Winkler

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Manzardo C, Esteve A, Ortega N, et al. Optimal timing for initiation of highly active antiretroviral therapy in treatment-naïve human immunodeficiency virus-1-infected individuals presenting with AIDS-defining diseases: the experience of the PISCIS Cohort. Clin. Microbiol. Infect. 2013 July;19(7):646-653. doi: 10.1111/j.1469-0691.2012.03991.x