Health Information Technology Commons^™

Remote Multi-Person Heart Rate Monitoring With Smart Speakers: Overcoming Separation Constraint, Ngoc Doan Thu Tran, Dong Ma, Rajesh Krishna Balan

Research Collection School Of Computing and Information Systems

Heart rate is a key vital sign that can be used to understand an individual’s health condition. Recently, remote sensing techniques, especially acoustic-based sensing, have received increasing attention for their ability to non-invasively detect heart rate via commercial mobile devices such as smartphones and smart speakers. However, due to signal interference, existing methods have primarily focused on monitoring a single user and required a large separation between them when monitoring multiple people. These limitations hinder many common use cases such as couples sharing the same bed or two or more people located in close proximity. In this paper, we present …

Enabling Ai And Robotic Coaches For Physical Rehabilitation Therapy: Iterative Design And Evaluation With Therapists And Post-Stroke Survivors, Min Hun Lee, Daniel Siewiorek, Asim Smailagic, Alexandre Bernardino, Sergi Bermúdez I Badia

Research Collection School Of Computing and Information Systems

Artificial intelligence (AI) and robotic coaches promise the improved engagement of patients on rehabilitation exercises through social interaction. While previous work explored the potential of automatically monitoring exercises for AI and robotic coaches, the deployment of these systems remains a challenge. Previous work described the lack of involving stakeholders to design such functionalities as one of the major causes. In this paper, we present our efforts on eliciting the detailed design specifications on how AI and robotic coaches could interact with and guide patient’s exercises in an effective and acceptable way with four therapists and five post-stroke survivors. Through iterative …

Selecting Patient-Reported Outcome Measures For A Patient-Facing Technology, Priyank Raj, Youmin Cho, Yun Jiang, Yang Gong

Faculty, Staff and Student Publications

OBJECTIVE: This article provides insight into our process and considerations for selecting patient-reported outcome measures (PROMs) designed for self-reporting symptoms and quality-of-life among breast cancer (BCA) patients undergoing oral anticancer agent treatment via a patient-facing technology (PFT) platform.

METHODS: Following established guidelines, we conducted a thorough assessment of a specific set of PROMs, comparing their content to identify the most suitable options for studying BCA patients.

RESULTS: We recommend utilizing the combination of EORTC QLQ-C30 + EORTC QLQ-BR45 as the preferred instrument, especially when developing a dedicated "breast cancer-only" application.

DISCUSSION: When developing and maintaining a dashboard for a PFT …

The Use Of Deception In Dementia-Care Robots: Should Robots Tell "White Lies" To Limit Emotional Distress?, Samuel R. Cox, Grace Cheong, Wei Tsang Ooi

ROSA Journal Articles and Publications

With projections of ageing populations and increasing rates of dementia, there is need for professional caregivers. Assistive robots have been proposed as a solution to this, as they can assist people both physically and socially. However, caregivers often need to use acts of deception (such as misdirection or white lies) in order to ensure necessary care is provided while limiting negative impacts on the cared-for such as emotional distress or loss of dignity. We discuss such use of deception, and contextualise their use within robotics.

Combat Covid-19 At National Level Using Risk Stratification With Appropriate Intervention, Xuan Jin, Kar Way Tan

Research Collection School Of Computing and Information Systems

In the national battle against COVID-19, harnessing population-level big data is imperative, enabling authorities to devise effective care policies, allocate healthcare resources efficiently, and enact targeted interventions. Singapore adopted the Home Recovery Programme (HRP) in September 2021, diverting low-risk COVID-19 patients to home care to ease hospital burdens amid high vaccination rates and mild symptoms. While a patient's suitability for HRP could be assessed using broad-based criteria, integrating machine learning (ML) model becomes invaluable for identifying high-risk patients prone to severe illness, facilitating early medical assessment. Most prior studies have traditionally depended on clinical and laboratory data, necessitating initial clinic …

Spatial-Temporal Episodic Memory Modeling For Adls: Encoding, Retrieval, And Prediction, Xinjing Song, Di Wang, Chai Quek, Ah-Hwee Tan, Yanjiang Wang

Research Collection School Of Computing and Information Systems

Activities of daily living (ADLs) relate to people’s daily self-care activities, which reflect their living habits and lifestyle. A prior study presented a neural network model called STADLART for ADL routine learning. In this paper, we propose a cognitive model named Spatial-Temporal Episodic Memory for ADL (STEM-ADL), which extends STADLART to encode event sequences in the form of distributed episodic memory patterns. Specifically, STEM-ADL encodes each ADL and its associated contextual information as an event pattern and encodes all events in a day as an episode pattern. By explicitly encoding the temporal characteristics of events as activity gradient patterns, STEM-ADL …

A Reliable And Secure Mobile Cyber-Physical Digital Microfluidic Biochip For Intelligent Healthcare, Yinan Yao, Decheng Qiu, Huangda Liu, Zhongliao Yang, Ximeng Liu, Yang Yang, Chen Dong

Research Collection School Of Computing and Information Systems

Digital microfluidic, as an emerging and potential technology, diversifies the biochemical applications platform, such as protein dilution sewage detection. At present, a vast majority of universal cyberphysical digital microfluidic biochips (DMFBs) transmit data through wires via personal computers and microcontrollers (like Arduino), consequently, susceptible to various security threats and with the popularity of wireless devices, losing competitiveness gradually. On the premise that security be ensured first and foremost, calls for wireless portable, safe, and economical DMFBs are imperative to expand their application fields, engage more users, and cater to the trend of future wireless communication. To this end, a new …

Towards A Virtual Reality Visualization Of Hand-Object Interactions To Support Remote Physical Therapy, Trudi Di Qi, Louanne Boyd, Scott Fitzpatrick, Meghna Raswan, Franceli L. Cibrian

Engineering Faculty Articles and Research

Improving object manipulation skills through hand-object interaction exercises is crucial for rehabilitation. Despite limited healthcare resources, physical therapists propose remote exercise routines followed up by remote monitoring. However, remote motor skills assessment remains challenging due to the lack of effective motion visualizations. Therefore, exploring innovative ways of visualization is crucial, and virtual reality (VR) has shown the potential to address this limitation. However, it is unclear how VR visualization can represent understandable hand-object interactions. To address this gap, in this paper, we present VRMoVi, a VR visualization system that incorporates multiple levels of 3D visualization layers to depict movements. In …

Innovation Process And Industrial System Of Us Food And Drug Administration-Approved Software As A Medical Device: Review And Content Analysis, Jiakan Yu, Jiajie Zhang, Shintaro Sengoku

Faculty, Staff and Student Publications

BACKGROUND: There has been a surge in academic and business interest in software as a medical device (SaMD). SaMD enables medical professionals to streamline existing medical practices and make innovative medical processes such as digital therapeutics a reality. Furthermore, SaMD is a billion-dollar market. However, SaMD is not clearly understood as a technological change and emerging industry.

OBJECTIVE: This study aims to review the landscape of SaMD in response to increasing interest in SaMD within health systems and regulation. The objectives of the study are to (1) clarify the innovation process of SaMD, (2) identify the prevailing typology of such …

Delivering Healthcare To The Underserved, Edward Booty

Asian Management Insights

Non-profits, governments, and businesses need to come together and use a data-driven approach to improve local basic healthcare access.

Understanding The Effect Of Counterfactual Explanations On Trust And Reliance On Ai For Human-Ai Collaborative Clinical Decision Making, Min Hun Lee, Chong Jun Chew

Research Collection School Of Computing and Information Systems

Artificial intelligence (AI) is increasingly being considered to assist human decision-making in high-stake domains (e.g. health). However, researchers have discussed an issue that humans can over-rely on wrong suggestions of the AI model instead of achieving human AI complementary performance. In this work, we utilized salient feature explanations along with what-if, counterfactual explanations to make humans review AI suggestions more analytically to reduce overreliance on AI and explored the effect of these explanations on trust and reliance on AI during clinical decision-making. We conducted an experiment with seven therapists and ten laypersons on the task of assessing post-stroke survivors' quality …

A Novel Fuzzy Relative-Position-Coding Transformer For Breast Cancer Diagnosis Using Ultrasonography, Yanhui Guo, Ruquan Jiang, Xin Gu, Heng-Da Cheng, Harish Garg

Computer Science Faculty and Staff Publications

Breast cancer is a leading cause of death in women worldwide, and early detection is crucial for successful treatment. Computer-aided diagnosis (CAD) systems have been developed to assist doctors in identifying breast cancer on ultrasound images. In this paper, we propose a novel fuzzy relative-position-coding (FRPC) Transformer to classify breast ultrasound (BUS) images for breast cancer diagnosis. The proposed FRPC Transformer utilizes the self-attention mechanism of Transformer networks combined with fuzzy relative-position-coding to capture global and local features of the BUS images. The performance of the proposed method is evaluated on one benchmark dataset and compared with those obtained by …

Weighted Mean Difference Statistics For Paired Data In The Presence Of Missing Values, Yuntong Li, Brent J. Shelton, William St Clair, Heidi L. Weiss, John L. Villano, Arnold Stromberg, Chi Wang, Li Chen

Markey Cancer Center Faculty Publications

Missing data is a common issue in many biomedical studies. Under a paired design, some subjects may have missing values in either one or both of the conditions due to loss of follow-up, insufficient biological samples, etc. Such partially paired data complicate statistical comparison of the distribution of the variable of interest between the two conditions. In this article, we propose a general class of test statistics based on the difference in weighted sample means without imposing any distributional or model assumption. An optimal weight is derived from this class of tests. Simulation studies show that our proposed test with …

How Technology May Be Used For Future Disease Predictions, Rich P. Manprisio

Journal of Applied Disciplines

Exasperated by the ongoing global pandemic, the healthcare system is grappling with the formidable challenges posed by proper and effective disease treatments. Nevertheless, amidst these growing difficulties, the healthcare field has witnessed significant technological advancements, offering promising avenues for disease prediction. Notably, a positive correlation exists between the utilization of technologies and their potential to serve as valuable tools for disease prediction. As our reliance on technological sophistication continues progressing, current research highlights numerous viable options to augment the healthcare sector. This review explores the current state of utilizing technologies and their potential to enhance healthcare, shedding light on their …

Balancing Privacy And Flexibility Of Cloud-Based Personal Health Records Sharing System, Yudi Zhang, Fuchun Guo, Willy Susilo, Guomin Yang

Research Collection School Of Computing and Information Systems

The Internet of Things and cloud services have been widely adopted in many applications, and personal health records (PHR) can provide tailored medical care. The PHR data is usually stored on cloud servers for sharing. Weighted attribute-based encryption (ABE) is a practical and flexible technique to protect PHR data. Under a weighted ABE policy, the data user's attributes will be “scored”, if and only if the score reaches the threshold value, he/she can access the data. However, while this approach offers a flexible access policy, the data owners have difficulty controlling their privacy, especially sharing PHR data in collaborative e-health …

Singapore's Hospital To Home Program: Raising Patient Engagement Through Ai, John Abisheganaden, Kheng Hock Lee, Lian Leng Low, Eugene Shum, Han Leong Goh, Christine Gian Lee Ang, Andy Wee An Ta, Steven M. Miller

Research Collection School Of Computing and Information Systems

Because of their complex care needs, many elderly patients are discharged from hospitals only to be readmitted for multiple stays within the following twelve months. John Abisheganaden and his fellow authors describe Singapore’s Hospital to Home program, a community care initiative fueled by artificial intelligence.

A New Method Using Deep Transfer Learning On Ecg To Predict The Response To Cardiac Resynchronization Therapy, Zhuo He, Hongjin Si, Xinwei Zhang, Qing-Hui Chen, Jiangang Zou, Weihua Zhou

Michigan Tech Publications

Background: Cardiac resynchronization therapy (CRT) has emerged as an effective treatment for heart failure patients with electrical dyssynchrony. However, accurately predicting which patients will respond to CRT remains a challenge. This study explores the application of deep transfer learning techniques to train a predictive model for CRT response. Methods: In this study, the short-time Fourier transform (STFT) technique was employed to transform ECG signals into two-dimensional images. A transfer learning approach was then applied on the MIT-BIT ECG database to pre-train a convolutional neural network (CNN) model. The model was fine-tuned to extract relevant features from the ECG images, and …

Patient Engagement In A Multimodal Digital Phenotyping Study Of Opioid Use Disorder, Cynthia I. Campbell, Ching-Hua Chen, Sara R. Adams, Asma Asyyed, Ninad R. Athale, Monique B. Does, Saeed Hassanpour, Emily Hichborn, Melanie Jackson-Morris, Nicholas C. Jacobson, Heather K. Jones, David Kotz, Chantal A. Lambert-Harris, Zhiguo Li, Bethany Mcleman, Varun Mishra, Catherine Stanger, Geetha Subramaniam, Weiyi Wu, Christopher Zegers, Lisa A. Marsch

Dartmouth Scholarship

Background: Multiple digital data sources can capture moment-to-moment information to advance a robust understanding of opioid use disorder (OUD) behavior, ultimately creating a digital phenotype for each patient. This information can lead to individualized interventions to improve treatment for OUD.

Objective: The aim is to examine patient engagement with multiple digital phenotyping methods among patients receiving buprenorphine medication for OUD.

Methods: The study enrolled 65 patients receiving buprenorphine for OUD between June 2020 and January 2021 from 4 addiction medicine programs in an integrated health care delivery system in Northern California. Ecological momentary assessment (EMA), sensor data, and social media …

Lessons Learned From The Hospital To Home Community Care Program In Singapore And The Supporting Ai Multiple Readmissions Prediction Model, John Abisheganaden, Kheng Hock Lee, Lian Leng Low, Eugene Shum, Han Leong Goh, Christine Gia Lee Ang, Adny An Ta Wee, Steven M. Miller

Research Collection School Of Computing and Information Systems

In a prior practice and policy article published in Healthcare Science, we introduced the deployed application of an artificial intelligence (AI) model to predict longer-term inpatient readmissions to guide community care interventions for patients with complex conditions in the context of Singapore's Hospital to Home (H2H) program that has been operating since 2017. In this follow on practice and policy article, we further elaborate on Singapore's H2H program and care model, and its supporting AI model for multiple readmission prediction, in the following ways: (1) by providing updates on the AI and supporting information systems, (2) by reporting on customer …

Tracing The Twenty-Year Evolution Of Developing Ai For Eye Screening In Singapore: A Master Chronology Of Sidrp, Selena+ And Eyris, Steven M. Miller

Research Collection School Of Computing and Information Systems

This working paper is entirely comprised of a timeline table that begins in 2002 and runs through mid-2023. Across these two decades, this timeline traces the evolutionary development of the following:

• The early Singapore R&D efforts to apply software-based image analysis algorithms and methods to analyse eye retina images for diabetic retinopathy and other eye diseases. This was based on a collaboration between the Singapore Eye Research Institute (SERI) and its parent organization, the Singapore National Eye Centre (SNEC), with faculty from the School of Computing at National University of Singapore.
• The establishment and operation of the Singapore Integrated Diabetic …

Quehry: A Question Answering System To Query Electronic Health Records, Sarvesh Soni, Surabhi Datta, Kirk Roberts

Faculty, Staff and Student Publications

OBJECTIVE: We propose a system, quEHRy, to retrieve precise, interpretable answers to natural language questions from structured data in electronic health records (EHRs).

MATERIALS AND METHODS: We develop/synthesize the main components of quEHRy: concept normalization (MetaMap), time frame classification (new), semantic parsing (existing), visualization with question understanding (new), and query module for FHIR mapping/processing (new). We evaluate quEHRy on 2 clinical question answering (QA) datasets. We evaluate each component separately as well as holistically to gain deeper insights. We also conduct a thorough error analysis for a crucial subcomponent, medical concept normalization.

RESULTS: Using gold concepts, the precision of quEHRy …

Feature Selection From Clinical Surveys Using Semantic Textual Similarity, Benjamin Warner

McKelvey School of Engineering Graduate Student Theses & Dissertations

Survey data collected from human subjects can contain a high number of features while having a comparatively low quantity of examples. Machine learning models that attempt to predict outcomes from survey data under these conditions can overfit and result in poor generalizability. One remedy to this issue is feature selection, which attempts to select an optimal subset of features to learn upon. A relatively unexplored source of information in the feature selection process is the usage of textual names of features, which may be semantically indicative of which features are relevant to a target outcome. The relationships between feature names …

Examining The Accuracy Of Two Commercially Available Global Positioning System Enabled Watches In Two Trail Conditions, Allison Tripure

Undergraduate Theses

The purpose of this investigation was to determine the accuracy of the GNSS (global navigation satellite system) in the Coros® Vertix 2 and Garmin® Fēnix 6 during two trail running conditions in a group of recreational trail runners. Six participants completed four self-paced, one-mile trail runs. Accuracy of the two watches in measuring distance were compared across two trail conditions, heavy and light tree coverage. Both watches were worn simultaneously and then switched to the opposite wrists for the next trial. Distance measured by the watches was reported every quarter mile. Mean and standard deviation of the distance measured by …

Combining Frameworks To Improve Military Health System Quality And Cybersecurity, Dr. Maureen L. Schafer, Dr. Joseph H. Schafer

Military Cyber Affairs

Existing conceptual frameworks and commercially available technology could be considered to rapidly operationalize the use of Quality Measures (QM) within military health systems (Costantino et al. 2020). Purchased healthcare as well as digital healthcare services have paved the way for data collection from multiple information systems thus offering stakeholders actionable intelligence to both guide and measure healthcare outcomes. However, the collection of data secondary to Smart Devices, disparate information systems, cloud services, and the Internet of Medical Things (IOMT) is a complication for security experts that also affect clients, stakeholders, organizations, and businesses delivering patient care. We have combined three …

Data Science For Hospital Antibiotic Stewardship, Saikou Jawla

Theses and Dissertations

Antibiotics are widely used to treat bacterial infections, but their misuse leads to antibiotic resistance. Antibiotic resistance is one of the biggest threats to global health, food security, and development today. Antibiotic resistance leads to higher medical costs, prolonged hospital stays, and increased mortality. Antimicrobial stewardship is an approach to measure and improve the appropriate use of antibiotics in healthcare settings. Data science has the potential to support these programs by providing insights into antibiotic prescribing patterns, identifying areas for improvement, and predicting patient outcomes. We explored the role of data science in hospital antibiotic stewardship programs, including statistical methods …

Exploring A Gradient-Based Explainable Ai Technique For Time-Series Data: A Case Study Of Assessing Stroke Rehabilitation Exercises, Min Hun Lee, Yi Jing Choy

Research Collection School Of Computing and Information Systems

Explainable artificial intelligence (AI) techniques are increasingly being explored to provide insights into why AI and machine learning (ML) models provide a certain outcome in various applications. However, there has been limited exploration of explainable AI techniques on time-series data, especially in the healthcare context. In this paper, we describe a threshold-based method that utilizes a weakly supervised model and a gradient-based explainable AI technique (i.e. saliency map) and explore its feasibility to identify salient frames of time-series data. Using the dataset from 15 post-stroke survivors performing three upper-limb exercises and labels on whether a compensatory motion is observed or …

The Impact Of Virtual Reality On The Healthcare Industry, Peter Sullivan

Honors Projects in Information Systems and Analytics

Virtual reality (VR) took off in 2013 and has touched many public sectors, from gaming, to business, to healthcare. This study looks at virtual reality's impact has affected the healthcare system, with a focus on its use for medical training, patient recovery, patient pain management, and mental health care. A literature review was conducted on the current state of the industry addressing virtual reality's performance in the field, the perception of experts, and an estimation of financial undertakings. Looking at cost analyses brought a fuller approach to the research. Surveying researchers and workers within the realm of healthcare and VR …

From Policy Promotion To Research Output: Brief Analysis Of Technical Challenges Of Hospital-Led Artificial Intelligence Research, Yu Zhuang, Cheng Zhou

Bulletin of Chinese Academy of Sciences (Chinese Version)

In recent years, artificial intelligence has become a key direction of medical and health-related research and a hot spot of international competition. In order to investigate the current situation and challenges in hospital-led artificial intelligence researched, this study selects 14 national pilot hospitals to promote the high-quality development of public hospitals as samples, adopts a combination of quantitative and qualitative methods, analyzes the research articles related to artificial intelligence published by the sample hospitals in recent years, and analyzes the technical challenges in the hospital-led artificial intelligence research. The results show that although the number of hospital-led artificial intelligence research …

Prediction Of Brain Metastases Development In Patients With Lung Cancer By Explainable Artificial Intelligence From Electronic Health Records, Zhao Li, Rongbin Li, Yujia Zhou, Laila Rasmy, Degui Zhi, Ping Zhu, Antonio Dono, Xiaoqian Jiang, Hua Xu, Yoshua Esquenazi, W Jim Zheng

Faculty, Staff and Student Publications

PURPOSE: Early detection of brain metastases (BMs) is critical for prompt treatment and optimal control of the disease. In this study, we seek to predict the risk of developing BM among patients diagnosed with lung cancer on the basis of electronic health record (EHR) data and to understand what factors are important for the model to predict BM development through explainable artificial intelligence approaches accurately.

MATERIALS AND METHODS: We trained a recurrent neural network model, REverse Time AttentIoN (RETAIN), to predict the risk of developing BM using structured EHR data. To interpret the model's decision process, we analyzed the attention …

A Scoping Review Of Digital Health Interventions For Combating Covid-19 Misinformation And Disinformation, Katarzyna Czerniak, Raji Pillai, Abhi Parmar, Kavita Ramnath, Joseph Krocker, Sahiti Myneni

Faculty, Staff and Student Publications

OBJECTIVE: We provide a scoping review of Digital Health Interventions (DHIs) that mitigate COVID-19 misinformation and disinformation seeding and spread.

MATERIALS AND METHODS: We applied our search protocol to PubMed, PsychINFO, and Web of Science to screen 1666 articles. The 17 articles included in this paper are experimental and interventional studies that developed and tested public consumer-facing DHIs. We examined these DHIs to understand digital features, incorporation of theory, the role of healthcare professionals, end-user experience, and implementation issues.

RESULTS: The majority of studies (n = 11) used social media in DHIs, but there was a lack of platform-agnostic generalizability. …