Health Information Technology Commons^™

Verifiable Outsourced Attribute-Based Encryption Scheme For Cloud-Assisted Mobile E-Health System, Yinbin Miao, Feng Li, Xinghua Li, Jianting Ning, Hongwei Li, Kim-Kwang Raymond Choo, Robert H. Deng

Research Collection School Of Computing and Information Systems

The cloud-assisted mobile electronic health (e-health) system facilitates e-health data sharing between healthcare providers and patients, but also raises the security and privacy concerns of e-health data. Although Ciphertext-Policy Attribute-Based Encryption (CP-ABE) has been a promising technique to achieve fine-grained access control over encrypted e-health data, it still incurs high encryption and decryption burdens on mobile users such as smartphones and sensors. In addition, malicious cloud servers may conduct incorrect operations due to various interest incentives (e.g., leaking sensitive information to illegal users, saving computation and storage costs). To solve the above issues, in this paper we first propose an …

Accessible Real-Time Eye-Gaze Tracking For Neurocognitive Health Assessments, A Multimodal Web-Based Approach, Daniel C. Tisdale

Master's Theses

We introduce a novel integration of real-time, predictive eye-gaze tracking models into a multimodal dialogue system tailored for remote health assessments. This system is designed to be highly accessible requiring only a conventional webcam for video input along with minimal cursor interaction and utilizes engaging gaze-based tasks that can be performed directly in a web browser. We have crafted dynamic subsystems that capture high-quality data efficiently and maintain quality through instances of user attrition and incomplete calls. Additionally, these subsystems are designed with the foresight to allow for future re-analysis using improved predictive models, as well as enable the creation …

Predicting Mild Cognitive Impairment Through Ambient Sensing And Artificial Intelligence, Ah-Hwee Tan, Weng Yan Ying, Budhitama Subagdja, Anni Huang, Shanthoshigaa D, Tony Chin-Ian Tay, Iris Rawtaer

Research Collection School Of Computing and Information Systems

This paper reports an emerging application leveraging ambient and artificial intelligence techniques for in-home sensing and cognitive health assessment. The application involves a prospective longitudinal study, wherein non-pervasive sensing devices are installed in homes of over 63 real users undergoing clinical cognitive assessment, and digital signals of the users’ activities and behaviour are transmitted to a central cloud-based data server for further processing and analysis. Based on the sensor readings, we identify a set of digital biomarkers covering four key aspects of daily living, namely physical, activity, cognitive, and sleep, and develop a suite of customized feature extraction methods for …

An Evaluation Of Heart Rate Monitoring With In-Ear Microphones Under Motion, Kayla-Jade Butkow, Ting Dang, Andrea Ferlini, Dong Ma, Yang Liu, Cecilia Mascolo

Research Collection School Of Computing and Information Systems

With the soaring adoption of in-ear wearables, the research community has started investigating suitable in-ear heart rate detection systems. Heart rate is a key physiological marker of cardiovascular health and physical fitness. Continuous and reliable heart rate monitoring with wearable devices has therefore gained increasing attention in recent years. Existing heart rate detection systems in wearables mainly rely on photoplethysmography (PPG) sensors, however, these are notorious for poor performance in the presence of human motion. In this work, leveraging the occlusion effect that enhances low-frequency bone-conducted sounds in the ear canal, we investigate for the first time in-ear audio-based motion-resilient …

Time-Controllable Keyword Search Scheme With Efficient Revocation In Mobile E-Health Cloud, Yinbin Miao, Feng Li, Xinghua Li, Zhiquan Liu, Jianting Ning, Hongwei Li, Kim-Kwang Raymond Choo, Deng, Robert H.

Research Collection School Of Computing and Information Systems

Electronic health (e-health) systems may outsource data such as patient e-health records to mobile cloud servers for efficiency gains (e.g., minimizing local storage and computation costs). However, such a move may result in privacy implications in the presence of semi-honest cloud servers. Searchable Encryption (SE) can potentially facilitate privacy-preserving searches based on keywords for encrypted data stored in the mobile cloud, but most existing SE solutions do not support temporal access control (i.e., a mechanism that grants access permissions to users for specified time ranges). Hence, in this paper we design a time-controllable keyword search scheme by using an attribute-based …

Representation Learning For Generative Models With Applications To Healthcare, Astronautics, And Aviation, Van Minh Nguyen

Theses and Dissertations

This dissertation explores applications of representation learning and generative models to challenges in healthcare, astronautics, and aviation.

The first part investigates the use of Generative Adversarial Networks (GANs) to synthesize realistic electronic health record (EHR) data. An initial attempt at training a GAN on the MIMIC-IV dataset encountered stability and convergence issues, motivating a deeper study of 1-Lipschitz regularization techniques for Auxiliary Classifier GANs (AC-GANs). An extensive ablation study on the CIFAR-10 dataset found that Spectral Normalization is key for AC-GAN stability and performance, while Weight Clipping fails to converge without Spectral Normalization. Analysis of the training dynamics provided further …

Exploring The Design Of Low-End Technology To Increase Patient Connectivity To Electronic Health Records, Rens Kievit, Abdullahi Abubakar Kawu, Mirjam Van Reisen, Dympna O'Sullivan, Lucy Hederman

Conference papers

The tracking of the vitals of patients with long term health problems is essential for clinicians to determine proper care. Using Patient Generated Health Data (PGHD) communicated remotely allows patients to be monitored without requiring frequent hospital visits. Issues might arise when the communication of data digitally is difficult or impossible due to a lack of access to internet or a low level of digital literacy as is the case in many African countries. The VODAN-Africa project (van Reisen et al., 2021) started in 2020 and has greatly increased the capabilities of clinics in different countries in both Africa and …

Eyris: From The Lab To The Market, Steven Miller, David Gomulya, Mahima Rao-Kachroo

Asian Management Insights

Singapore’s trailblazer AI algorithm for detecting diabetes-related eye diseases. Can you imagine getting the results of your eye disease screening within minutes rather than days? This capability is what EyRIS, a Singapore-based start-up that uses the AI (Artificial Intelligence)-driven Singapore Eye LEsion Analyzer (SELENA+) algorithm to screen for diabetes-related eye diseases, set out to productise and commercialise.

Transiam: Aggregating Multi-Modal Visual Features With Locality For Medical Image Segmentation, Xuejian Li, Shiqiang Ma, Junhai Xu, Jijun Tang, Shengfeng He, Fei Guo

Research Collection School Of Computing and Information Systems

Automatic segmentation of medical images plays an important role in the diagnosis of diseases. On single-modal data, convolutional neural networks have demonstrated satisfactory performance. However, multi-modal data encompasses a greater amount of information rather than single-modal data. Multi-modal data can be effectively used to improve the segmentation accuracy of regions of interest by analyzing both spatial and temporal information. In this study, we propose a dual-path segmentation model for multi-modal medical images, named TranSiam. Taking into account that there is a significant diversity between the different modalities, TranSiam employs two parallel CNNs to extract the features which are specific to …

Navigating Through Chaos, Hoong Chuin Lau

Asian Management Insights

How AI and optimisation models can strengthen supply chain resilience.

Public Acceptance Of Using Artificial Intelligence-Assisted Weight Management Apps In High-Income Southeast Asian Adults With Overweight And Obesity: A Cross-Sectional Study, Han Shi Jocelyn Chew, Palakorn Achananuparp, Palakorn Achananuparp, Nicholas W. S. Chew, Yip Han Chin, Yujia Gao, Bok Yan Jimmy So, Asim Shabbir, Ee-Peng Lim, Kee Yuan Ngiam

Research Collection School Of Computing and Information Systems

Introduction: With in increase in interest to incorporate artificial intelligence (AI) into weight management programs, we aimed to examine user perceptions of AI-based mobile apps for weight management in adults with overweight and obesity. Methods: 280 participants were recruited between May and November 2022. Participants completed a questionnaire on sociodemographic profiles, Unified Theory of Acceptance and Use of Technology 2 (UTAUT2), and Self-Regulation of Eating Behavior Questionnaire. Structural equation modeling was performed using R. Model fit was tested using maximum-likelihood generalized unweighted least squares. Associations between influencing factors were analyzed using correlation and linear regression. Results: 271 participant responses were …

A Comprehensive And Comparative Examination Of Healthcare Data Breaches: Assessing Security, Privacy, And Performance, Mohammed Al Kinoon

Graduate Thesis and Dissertation 2023-2024

The healthcare sector is pivotal, offering life-saving services and enhancing well-being and community life quality, especially with the transition from paper-based to digital electronic health records (EHR). While improving efficiency and patient safety, this digital shift has also made healthcare a prime target for cybercriminals. The sector's sensitive data, including personal identification information, treatment records, and SSNs, are valuable for illegal financial gains. The resultant data breaches, increased by interconnected systems, cyber threats, and insider vulnerabilities, present ongoing and complex challenges. In this dissertation, we tackle a multi-faceted examination of these challenges. We conducted a detailed analysis of healthcare data …

Machine Learning Algorithms To Study Multi-Modal Data For Computational Biology, Khandakar Tanvir Ahmed

Graduate Thesis and Dissertation 2023-2024

Advancements in high-throughput technologies have led to an exponential increase in the generation of multi-modal data in computational biology. These datasets, comprising diverse biological measurements such as genomics, transcriptomics, proteomics, metabolomics, and imaging data, offer a comprehensive view of biological systems at various levels of complexity. However, integrating and analyzing such heterogeneous data present significant challenges due to differences in data modalities, scales, and noise levels. Another challenge for multi-modal analysis is the complex interaction network that the modalities share. Understanding the intricate interplay between different biological modalities is essential for unraveling the underlying mechanisms of complex biological processes, including …

Data Driven Trade-Off Analysis For Cybersecurity, Goskel Kucukkaya, Murat Ozer, Murat Balci, Emrah Ugurlu

Engineering Management & Systems Engineering Faculty Publications

Trade-off analysis, a specialization of systems engineering, addresses design criteria like security, cost, performance, and compliance. Monte Carlo simulations are commonly employed to generate impact scenarios for trade-off analysis combined with solution alternatives that accommodate industry-specific considerations and uncertainties. In the cyber domain, this paper proposes a methodology for data-driven trade-off analysis in cybersecurity, leveraging industry reports as primary data sources using confidentiality, integrity, and availability as trade-off analysis objectives. Distribution functions are derived to manage and model uncertainties for various industries. The approach given in this study aims to facilitate informed choices and to enhance cybersecurity decision making and …

Infusing Machine Learning And Computational Linguistics Into Clinical Notes, Funke V. Alabi, Onyeka Omose, Omotomilola Jegede

Mathematics & Statistics Faculty Publications

Entering free-form text notes into Electronic Health Records (EHR) systems takes a lot of time from clinicians. A large portion of this paper work is viewed as a burden, which cuts into the amount of time doctors spend with patients and increases the risk of burnout. We will see how machine learning and computational linguistics can be infused in the processing of taking clinical notes. We are presenting a new language modeling task that predicts the content of notes conditioned on historical data from a patient's medical record, such as patient demographics, lab results, medications, and previous notes, with the …

Designing A Blockchain-Empowered Telehealth Artifact For Decentralized Identity Management And Trustworthy Communication: Interdisciplinary Approach, Xueping Liang, Nabid Alam, Tahmina Sultana, Eranga Bandara, Sachin Shetty

VMASC Publications

Background: Telehealth played a critical role during the COVID-19 pandemic and continues to function as an essential component of health care. Existing platforms cannot ensure privacy and prevent cyberattacks.

Objective: The main objectives of this study are to understand existing cybersecurity issues in identity management and trustworthy communication processes in telehealth platforms and to design a software architecture integrated with blockchain to improve security and trustworthiness with acceptable performance.

Methods: We improved personal information security in existing telehealth platforms by adopting an innovative interdisciplinary approach combining design science, social science, and computer science in the health care domain, with prototype …

Remote Multi-Person Heart Rate Monitoring With Smart Speakers: Overcoming Separation Constraint, Ngoc Doan Thu Tran, Dong Ma, Rajesh Krishna Balan

Research Collection School Of Computing and Information Systems

Heart rate is a key vital sign that can be used to understand an individual’s health condition. Recently, remote sensing techniques, especially acoustic-based sensing, have received increasing attention for their ability to non-invasively detect heart rate via commercial mobile devices such as smartphones and smart speakers. However, due to signal interference, existing methods have primarily focused on monitoring a single user and required a large separation between them when monitoring multiple people. These limitations hinder many common use cases such as couples sharing the same bed or two or more people located in close proximity. In this paper, we present …

Enabling Ai And Robotic Coaches For Physical Rehabilitation Therapy: Iterative Design And Evaluation With Therapists And Post-Stroke Survivors, Min Hun Lee, Daniel Siewiorek, Asim Smailagic, Alexandre Bernardino, Sergi Bermúdez I Badia

Research Collection School Of Computing and Information Systems

Artificial intelligence (AI) and robotic coaches promise the improved engagement of patients on rehabilitation exercises through social interaction. While previous work explored the potential of automatically monitoring exercises for AI and robotic coaches, the deployment of these systems remains a challenge. Previous work described the lack of involving stakeholders to design such functionalities as one of the major causes. In this paper, we present our efforts on eliciting the detailed design specifications on how AI and robotic coaches could interact with and guide patient’s exercises in an effective and acceptable way with four therapists and five post-stroke survivors. Through iterative …

The Use Of Deception In Dementia-Care Robots: Should Robots Tell "White Lies" To Limit Emotional Distress?, Samuel R. Cox, Grace Cheong, Wei Tsang Ooi

ROSA Journal Articles and Publications

With projections of ageing populations and increasing rates of dementia, there is need for professional caregivers. Assistive robots have been proposed as a solution to this, as they can assist people both physically and socially. However, caregivers often need to use acts of deception (such as misdirection or white lies) in order to ensure necessary care is provided while limiting negative impacts on the cared-for such as emotional distress or loss of dignity. We discuss such use of deception, and contextualise their use within robotics.

Combat Covid-19 At National Level Using Risk Stratification With Appropriate Intervention, Xuan Jin, Kar Way Tan

Research Collection School Of Computing and Information Systems

In the national battle against COVID-19, harnessing population-level big data is imperative, enabling authorities to devise effective care policies, allocate healthcare resources efficiently, and enact targeted interventions. Singapore adopted the Home Recovery Programme (HRP) in September 2021, diverting low-risk COVID-19 patients to home care to ease hospital burdens amid high vaccination rates and mild symptoms. While a patient's suitability for HRP could be assessed using broad-based criteria, integrating machine learning (ML) model becomes invaluable for identifying high-risk patients prone to severe illness, facilitating early medical assessment. Most prior studies have traditionally depended on clinical and laboratory data, necessitating initial clinic …

Spatial-Temporal Episodic Memory Modeling For Adls: Encoding, Retrieval, And Prediction, Xinjing Song, Di Wang, Chai Quek, Ah-Hwee Tan, Yanjiang Wang

Research Collection School Of Computing and Information Systems

Activities of daily living (ADLs) relate to people’s daily self-care activities, which reflect their living habits and lifestyle. A prior study presented a neural network model called STADLART for ADL routine learning. In this paper, we propose a cognitive model named Spatial-Temporal Episodic Memory for ADL (STEM-ADL), which extends STADLART to encode event sequences in the form of distributed episodic memory patterns. Specifically, STEM-ADL encodes each ADL and its associated contextual information as an event pattern and encodes all events in a day as an episode pattern. By explicitly encoding the temporal characteristics of events as activity gradient patterns, STEM-ADL …

A Reliable And Secure Mobile Cyber-Physical Digital Microfluidic Biochip For Intelligent Healthcare, Yinan Yao, Decheng Qiu, Huangda Liu, Zhongliao Yang, Ximeng Liu, Yang Yang, Chen Dong

Research Collection School Of Computing and Information Systems

Digital microfluidic, as an emerging and potential technology, diversifies the biochemical applications platform, such as protein dilution sewage detection. At present, a vast majority of universal cyberphysical digital microfluidic biochips (DMFBs) transmit data through wires via personal computers and microcontrollers (like Arduino), consequently, susceptible to various security threats and with the popularity of wireless devices, losing competitiveness gradually. On the premise that security be ensured first and foremost, calls for wireless portable, safe, and economical DMFBs are imperative to expand their application fields, engage more users, and cater to the trend of future wireless communication. To this end, a new …

Delivering Healthcare To The Underserved, Edward Booty

Asian Management Insights

Non-profits, governments, and businesses need to come together and use a data-driven approach to improve local basic healthcare access.

Understanding The Effect Of Counterfactual Explanations On Trust And Reliance On Ai For Human-Ai Collaborative Clinical Decision Making, Min Hun Lee, Chong Jun Chew

Research Collection School Of Computing and Information Systems

Artificial intelligence (AI) is increasingly being considered to assist human decision-making in high-stake domains (e.g. health). However, researchers have discussed an issue that humans can over-rely on wrong suggestions of the AI model instead of achieving human AI complementary performance. In this work, we utilized salient feature explanations along with what-if, counterfactual explanations to make humans review AI suggestions more analytically to reduce overreliance on AI and explored the effect of these explanations on trust and reliance on AI during clinical decision-making. We conducted an experiment with seven therapists and ten laypersons on the task of assessing post-stroke survivors' quality …

A Novel Fuzzy Relative-Position-Coding Transformer For Breast Cancer Diagnosis Using Ultrasonography, Yanhui Guo, Ruquan Jiang, Xin Gu, Heng-Da Cheng, Harish Garg

Computer Science Faculty and Staff Publications

Breast cancer is a leading cause of death in women worldwide, and early detection is crucial for successful treatment. Computer-aided diagnosis (CAD) systems have been developed to assist doctors in identifying breast cancer on ultrasound images. In this paper, we propose a novel fuzzy relative-position-coding (FRPC) Transformer to classify breast ultrasound (BUS) images for breast cancer diagnosis. The proposed FRPC Transformer utilizes the self-attention mechanism of Transformer networks combined with fuzzy relative-position-coding to capture global and local features of the BUS images. The performance of the proposed method is evaluated on one benchmark dataset and compared with those obtained by …

How Technology May Be Used For Future Disease Predictions, Rich P. Manprisio

Journal of Applied Disciplines

Exasperated by the ongoing global pandemic, the healthcare system is grappling with the formidable challenges posed by proper and effective disease treatments. Nevertheless, amidst these growing difficulties, the healthcare field has witnessed significant technological advancements, offering promising avenues for disease prediction. Notably, a positive correlation exists between the utilization of technologies and their potential to serve as valuable tools for disease prediction. As our reliance on technological sophistication continues progressing, current research highlights numerous viable options to augment the healthcare sector. This review explores the current state of utilizing technologies and their potential to enhance healthcare, shedding light on their …

Balancing Privacy And Flexibility Of Cloud-Based Personal Health Records Sharing System, Yudi Zhang, Fuchun Guo, Willy Susilo, Guomin Yang

Research Collection School Of Computing and Information Systems

The Internet of Things and cloud services have been widely adopted in many applications, and personal health records (PHR) can provide tailored medical care. The PHR data is usually stored on cloud servers for sharing. Weighted attribute-based encryption (ABE) is a practical and flexible technique to protect PHR data. Under a weighted ABE policy, the data user's attributes will be “scored”, if and only if the score reaches the threshold value, he/she can access the data. However, while this approach offers a flexible access policy, the data owners have difficulty controlling their privacy, especially sharing PHR data in collaborative e-health …

Singapore's Hospital To Home Program: Raising Patient Engagement Through Ai, John Abisheganaden, Kheng Hock Lee, Lian Leng Low, Eugene Shum, Han Leong Goh, Christine Gian Lee Ang, Andy Wee An Ta, Steven M. Miller

Research Collection School Of Computing and Information Systems

Because of their complex care needs, many elderly patients are discharged from hospitals only to be readmitted for multiple stays within the following twelve months. John Abisheganaden and his fellow authors describe Singapore’s Hospital to Home program, a community care initiative fueled by artificial intelligence.

A New Method Using Deep Transfer Learning On Ecg To Predict The Response To Cardiac Resynchronization Therapy, Zhuo He, Hongjin Si, Xinwei Zhang, Qing-Hui Chen, Jiangang Zou, Weihua Zhou

Michigan Tech Publications

Background: Cardiac resynchronization therapy (CRT) has emerged as an effective treatment for heart failure patients with electrical dyssynchrony. However, accurately predicting which patients will respond to CRT remains a challenge. This study explores the application of deep transfer learning techniques to train a predictive model for CRT response. Methods: In this study, the short-time Fourier transform (STFT) technique was employed to transform ECG signals into two-dimensional images. A transfer learning approach was then applied on the MIT-BIT ECG database to pre-train a convolutional neural network (CNN) model. The model was fine-tuned to extract relevant features from the ECG images, and …

Patient Engagement In A Multimodal Digital Phenotyping Study Of Opioid Use Disorder, Cynthia I. Campbell, Ching-Hua Chen, Sara R. Adams, Asma Asyyed, Ninad R. Athale, Monique B. Does, Saeed Hassanpour, Emily Hichborn, Melanie Jackson-Morris, Nicholas C. Jacobson, Heather K. Jones, David Kotz, Chantal A. Lambert-Harris, Zhiguo Li, Bethany Mcleman, Varun Mishra, Catherine Stanger, Geetha Subramaniam, Weiyi Wu, Christopher Zegers, Lisa A. Marsch

Dartmouth Scholarship

Background: Multiple digital data sources can capture moment-to-moment information to advance a robust understanding of opioid use disorder (OUD) behavior, ultimately creating a digital phenotype for each patient. This information can lead to individualized interventions to improve treatment for OUD.

Objective: The aim is to examine patient engagement with multiple digital phenotyping methods among patients receiving buprenorphine medication for OUD.

Methods: The study enrolled 65 patients receiving buprenorphine for OUD between June 2020 and January 2021 from 4 addiction medicine programs in an integrated health care delivery system in Northern California. Ecological momentary assessment (EMA), sensor data, and social media …