Health Information Technology Commons^™

Predicting Coronary Artery Disease With Medical Profile And Gene Polymorphisms Data, Qiongyu Chen, Guoliang Li, Tze-Yun Leong, Chew-Kiat Heng

Research Collection School Of Computing and Information Systems

Coronary artery disease (CAD) is a main cause of death in the world. Finding cost-effective methods to predict CAD is a major challenge in public health. In this paper, we investigate the combined effects of genetic polymorphisms and non-genetic factors on predicting the risk of CAD by applying well known classification methods, such as Bayesian networks, naïve Bayes, support vector machine, k-nearest neighbor, neural networks and decision trees. Our experiments show that all these classifiers are comparable in terms of accuracy, while Bayesian networks have the additional advantage of being able to provide insights into the relationships among the variables. …

A Time-And-Value Centric Provenance Model And Architecture For Medical Event Streams, Marion Bllount, John Davis, Archan Misra, Daby Sow, Min Wang

Research Collection School Of Computing and Information Systems

Provenance becomes a critical requirement for healthcare IT infrastructures, especially when pervasive biomedical sensors act as a source of raw medical streams for large-scale, automated clinical decision support systems. Medical and legal requirements will make it obligatory for such systems to answer queries regarding the underlying data samples from which output alerts are derived, the IDs of the processing components used and the privileges of the individuals and software components accessing the medical data. Unfortunately, existing models of either annotation or process based provenance are designed for transaction-oriented systems and do not satisfy the unique requirements for systems processing high-volume, …

Information Governance: A Model For Security In Medical Practice, Patricia Williams

Research outputs pre 2011

Information governance is becoming an important aspect of organisational accountability. In consideration that information is an integral asset of most organisations, the protection of this asset will increasingly rely on organisational capabilities in security. In the medical arena this information is primarily sensitive patient-based information'. Previous research has shown that application of security measures is a low priority for primary care medical practice and that awareness of the risks are seriously underestimated. Consequently, information security governance will be a key issue for medical practice in the future. Information security governance is a relatively new term ,and there is little existing …

Set-Based Cascading Approaches For Magnetic Resonance (Mr) Image Segmentation (Scamis), Jiang Liu, Tze-Yun Leong, Kin Ban Chee, Boon Pin Tan, Borys Shuter, Shih Chang Wang

Research Collection School Of Computing and Information Systems

This paper introduces Set-based Cascading Approach for Medical Image Segmentation (SCAMIS), a new methodology for segmentation of medical imaging by integrating a number of algorithms. Existing approaches typically adopt the pipeline methodology. Although these methods provide promising results, the results generated are still susceptible to over-segmentation and leaking. In our methodology, we describe how set operations can be utilized to better overcome these problems. To evaluate the effectiveness of this approach, Magnetic Resonance Images taken from a teaching hospital research programme have been utilised, to reflect the real world quality needed for testing in patient datasets. A comparison between the …

Mobile Healthcare Informatics, Keng Siau, Zixing Shen

Research Collection School Of Computing and Information Systems

Advances in wireless technology give pace to the rapid development of mobile applications. The coming mobile revolution will bring dramatic and fundamental changes to our daily life. It will influence the way we live, the way we do things, and the way we take care of our health. For the healthcare industry, mobile applications provide a new frontier in offering better care and services to patients, and a more flexible and mobile way of communicating with suppliers and patients. Mobile applications will provide important real time data for patients, physicians, insurers, and suppliers. In addition, it will revolutionalize the way …

A Database And Tool, Im Browser, For Exploring And Integrating Emerging Gene And Protein Interaction Data For Drosophila, Svetlana Pacifico, Guozhen Liu, Stephen Guest, Jodi R. Parrish, Farshad Fotouhi, Russell L. Finley Jr

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Biological processes are mediated by networks of interacting genes and proteins. Efforts to map and understand these networks are resulting in the proliferation of interaction data derived from both experimental and computational techniques for a number of organisms. The volume of this data combined with the variety of specific forms it can take has created a need for comprehensive databases that include all of the available data sets, and for exploration tools to facilitate data integration and analysis. One powerful paradigm for the navigation and analysis of interaction data is an interaction graph or map that represents proteins …

K-Spmm: A Database Of Murine Spermatogenic Promoters Modules & Motifs, Yi Lu, Adrian E. Platts, G Charles Ostermeier, Stephen A. Krawetz

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Understanding the regulatory processes that coordinate the cascade of gene expression leading to male gamete development has proven challenging. Research has been hindered in part by an incomplete picture of the regulatory elements that are both characteristic of and distinctive to the broad population of spermatogenically expressed genes.

Description

K-SPMM, a database of murine Spermatogenic Promoters Modules and Motifs, has been developed as a web-based resource for the comparative analysis of promoter regions and their constituent elements in developing male germ cells. The system contains data on 7,551 genes and 11,715 putative promoter regions …

Information Systems And Health Care Xiii: Examining The Critical Requirements, Design Approaches And Evaluation Methods For A Public Health Emergency Response System, Ann L. Fruhling

Information Systems and Quantitative Analysis Faculty Publications

Research pertaining to emergency response systems has accelerated over the past few years, particularly since 9/11 events, and more recently due to Hurricane Katrina and concern over a potential of an avian flu pandemic. This study examines the requirements that are the most demanding with respect to software and hardware, and the associated design strategies for a public health emergency response system (ERS) for electronic laboratory diagnostics consultation. In addition, this study illustrates ways to evaluate the design decisions.

An important goal of a public health ERS is to improve the communication and notification of life-threatening diseases and harmful agents. …

Towards Knowledge Morphing: A Triangulation Approach To Link Tacit And Explicit Knowledge, Fehmida Hussain, Syed Sibte Raza Abidi, Syed Ali Raza

International Conference on Information and Communication Technologies

Current knowledge management systems are largely designed to deal with a single knowledge modality. Given the diversity of knowledge modalities that encompass any given topic/problem it is reasonable to demand access and use of all available knowledge, irrespective of their representation modality, to derive a knowledge-mediated solution. This calls for selecting all knowledge elements (represented in different modalities) that are relevant to the solution of the problem at hand. Thus here we pursue the specification and implementation of such a knowledge-mediated solution using a triangulation approach leading to Knowledge Morphing. In this paper we present a tacit-explicit knowledge morphing (TEKM) …

Antes: A Web-Based Acanthosis Nigricans And Other Obesity Related Information System, Chunyue Wang

Theses and Dissertations - UTB/UTPA

Acanthosis nigricans is a cutaneous marker associated with systemic disorders and may serve as an indicator for risk of Type 2 diabetes. Acanthosis nigricans screening can help identify children who have high insulin levels and who may be at-risk for developing Type 2 diabetes. The ANTES system is a computerization attempt for acanthosis nigricans control of the student population from elementary schools and secondary schools in Texas. A general description of the system and the medical and history background of the ANTES program is given. The technology applied to the system is demonstrated. An overview of the system operation status …

Health Care Informatics, Keng Siau

Research Collection School Of Computing and Information Systems

The health care industry is currently experiencing a fundamental change. Health care organizations are reorganizing their processes to reduce costs, be more competitive, and provide better and more personalized customer care. This new business strategy requires health care organizations to implement new technologies, such as Internet applications, enterprise systems, and mobile technologies in order to achieve their desired business changes. This article offers a conceptual model for implementing new information systems, integrating internal data, and linking suppliers and patients.

Mining Of Correlated Rules In Genome Sequences, L. Lin, L. Wong, Tze-Yun Leong, P. S. Lai

Research Collection School Of Computing and Information Systems

With the huge amount of data collected by scientists in the molecular genetics community in recent years, there exists a need to develop some novel algorithms based on existing data mining techniques to discover useful information from genome databases. We propose an algorithm that integrates the statistical method, association rule mining, and classification rule mining in the discovery of allelic combinations of genes that are peculiar to certain phenotypes of diseased patients.

Internet Usage Among Medical Doctors In Malaysia, Surendran Jaganathan

Student Works (2000-2009)

In Malaysia, there were 20,000 Internet subscribers in 1996, 1.5 Million in 2000 and it is predicted to reach 4.5 Million in 2004. Malaysia is experiencing an explosive growth of Internet users. There is also a growing importance of "e -health businesses" as shown in the existing 20,000 healthcare sites currently online with an additional 1,500 sites being added every month. This translates to increasing healthcare site users for instance in America alone, out of 11 o million Internet users, 70 million searched the Web for health information. For healthcare consumers worldwide, the Internet has now become a tool for …

Nonparametric Techniques To Extract Fuzzy Rules For Breast Cancer Diagnosis Problem, Manish Sarkar, Tze-Yun Leong

Research Collection School Of Computing and Information Systems

This paper addresses breast cancer diagnosis problem as a pattern classification problem. Specifically, the problem is studied using Wisconsin-Madison breast cancer data set. Fuzzy rules are generated from the input-output relationship so that the diagnosis becomes easier and transparent for both patients and physicians. For each class, at least one training pattern is chosen as the prototype, provided (a) the maximum membership of the training pattern is in the given class, and (b) among all the training patterns, the neighborhood of this training pattern has the least fuzzy-rough uncertainty in the given class. Using the fuzzy-rough uncertainty, a cluster is …

Interactive First Aid Guidebook, Pen San Lai

Student Works (2000-2009)

'Interactive First Aid Guidebook' is an information-based web sites that will be providing a comprehensive collection of multiple type of first aid situation and solution. The development of these web sites is to increase the awareness of First-Aid knowledge through Internet. Besides that, the development of this interactive-web based web site is to aid and ease the process of learning first aid. From the review of literature have enriched the understanding of Interactivity. 'interactive First aid Guidebook' will be a interactive web site in order to respond dynamically to user control by implementing the computer-aided instruction approach. The Computer-Aided instruction …

Smart Healthcare Information System Pharmacy Management System, Weng Yuen Leow

Student Works (2000-2009)

This document covers 3 main areas in outlining the intended system in question; that is the Pharmacy Management System. The first section of this document is basically an introduction to the system. It covers the objective of the said system as well as the scope and area that it would cover. It also explains briefly its interaction and integration with other components being developed by 4 other course mates in the team. The Pharmacy Management System is a part of a larger system that we have dubbed as the "Smart Healthcare Information System". The second section covers an in-depth study …

A Web Based Healthcare Management System, Farid Abdullah Muhammad

Student Works (2000-2009)

The project generally involved around the basic information about medical, health, drugs and diseases. This kind of information is vital yet has a very limited access. The tradition that when we get sick then we go to see doctor and ate whatever medicine that the doctor gave well, does not apply here anymore. People should know at least a simple thing about their health or medical status. They should know what they eat, what cause the illness or how to prevent it. This is possible as the system target on medical student and the public to make the system useful …

Decision Support Methods In Diabetic Patient Management By Insulin Administration Neural Network Vs. Induction Methods For Knowledge Classification, B. V. Ambrosiadou, S. Vadera, Venky Shankaraman, D. Goulis, G. Gogou

Research Collection School Of Computing and Information Systems

Diabetes mellitus is now recognised as a major worldwide public health problem. At present, about 100 million people are registered as diabetic patients. Many clinical, social and economic problems occur as a consequence of insulin-dependent diabetes. Treatment attempts to prevent or delay complications by applying ‘optimal’ glycaemic control. Therefore, there is a continuous need for effective monitoring of the patient. Given the popularity of decision tree learning algorithms as well as neural networks for knowledge classification which is further used for decision support, this paper examines their relative merits by applying one algorithm from each family on a medical problem; …

An International Cross-Cultural Study Of The Role Of Chief Informational Officers In Healthcare, Wallace Saunders

Faculty Dissertations

The introduction and utilization of Information Systems (IS) in the hospital environment has had a significant and lasting impact on the practice of medicine. The development of this dissertation will attempt to explore a widely overlooked area: The comparison of Chief Information Officers (CIOs) in the United States and the United Kingdom.

Aspects of CIO experiences relating to assumed roles, CIO challenges, skills, frustrations, success, failure, leadership, management, involvement and perceptions about the role of Information Technology (IT) in healthcare are discussed with a comparative global model. This study investigates the managerial roles of the Chief Information Officer based on …

Sistem Maklumbalas Bagi Sistem Maklumat Kesihatan, Abu Bakar Siti Fatimah

Student Works (2000-2009)

Perkembangan teknologi dan industri komputer yang semakin pesat, kini menjadi medan utama untuk setiap pihak bersaing. Penyediaan aspek mudah dan pantas menjadi pilihan utama dalam menghasilkan kerja yang lebih produktif dan berkualiti serta hasil kerja yang terbaik. Perkembangan yang positif ini membantu meningkatkan mutu pengurusan termasuklah pengurusan sistem. Sistem maklumbalas bagi sistem maklumat kesihatan, iaitu Sistem MBK yang akan dibangunkan ini bertujuan untuk membantu pihak yang terlibat da1am melicinkan urusan dan membantu mengatasi masalah yang dihadapi jika sistem manual digunakan. Tujuan pembangunan Sistem MBK ini adalah supaya pengguna dapat memberikan maklumbalas kepada pusat kesihatan dengan lebih mudah dan cepat. Sistem …

Information Technology In The Health Care Industry: A Primer, P. Southard, S. J. Hong, Keng Siau

Research Collection School Of Computing and Information Systems

The paper discusses current and future applications of information technology within the healthcareindustry. It presents some broad strategies for approaching information technology investments and various tools available.

A System To Keep Track Of Medical Expertise (Medix), Kasthuri Subaramaniam

Student Works (2000-2009)

This dissertation presents a system for keeping track of medical expertise as well as demonstrates the integration of different tools in a single application. MediX, a system to keep track of medical expertise, maintains the records of medical expertise, medical centres and specialties. MediX uses reporting, statistical, database, and authoring tools that are integrated in a programming package running under an operating system. MediX is a client/server-based system that has many significant features. MediX provides the tools necessary to view existing information in new forms and combinations. These include generation of reports. charts and graphs as well as statistical computing, …

A System For Analysing Patient History (Az-Phis), Kemalatha Krishnasamy

Student Works (2000-2009)

The improvement of health care service has a great effect on patient satisfaction. In order to improve the health care service, effective processing of patient history and analysis on the respondent is necessary. The results of the statistical analysis performed on patient history eases the decision making of physicians and other related medical staff. Therefore, this dissertation mainly investigates information pertaining to patient history, statistical analysis, and development of a system for analyzing patient history. The study employs the questionnaire survey method to gather data and make analyses using the Spreadsheet; Microsoft® Excel 97. The survey was done in government …

Benchmarking Financial Operations Using The Premier Operations Outlook Database, Margaret M. Thompson

Community & Environmental Health Theses & Dissertations

Acute-care hospitals have come under increased pressure to reduce costs while increasing the quality of providing care. Historically, increasing costs of providing care has had the greatest impact on the reduction of operating margins necessary to expand capital and for repayment of debt. Facilities can benchmark internal historical data to identify areas where costs have increased and are able to explain the factors that contribute to the increases. One of the challenges facing hospitals in their efforts to reduce operating costs is how, what, and where, do they obtain comparative data to benchmark the cost of operating medical facility to …

Decision Analytic Approach To Severe Head Injury Management., Harmanec D., Tze-Yun Leong, Sundaresh S., Poh K., Yeo T., Ng I., Lew T.

Research Collection School Of Computing and Information Systems

Severe head injury management in the intensive care unit is extremely challenging due to the complex domain, the uncertain intervention efficacies, and the time-critical setting. We adopt a decision analytic approach to automate the management process. We document our experience in building a simplified influence diagram that involves about 3000 numerical parameters. We identify the inherent problems in structuring a model with unclear domain relationships, numerous interacting variables, and real-time multiple inputs. We analyze the effectiveness and limitations of the decision analytic approach and present a set of desiderata for effective knowledge acquisition in this setting. We also propose a …

Modelling Medical Decisions In Dynamol: A New General Framework Of Dynamic Decision Analysis, Tze-Yun Leong, Cungen Cao

Research Collection School Of Computing and Information Systems

Dynamic decision analysis concerns decision problems in which both time and uncertainty are explicitly considered. We present a new dynamic decision analysis framework, called DynamoL, that supports graphical presentation of the decision factors in multiple perspectives. To alleviate the difficulty in assessing conditional probabilities over time in dynamic decision models, DynaMoL incorporates a Bayesian learning system to automatically learn the probabilistic parameters from large medical databases. We describe the DynaMoL modeling and learning architecture through a medical decision problem on the optimal follow-up schedule for patients after curative colorectal cancer surgery. We also show that the modeling experience and results …

Dynamic Decision Modeling In Medicine: A Critique Of Existing Formalisms, Tze-Yun Leong

Research Collection School Of Computing and Information Systems

Dynamic decision models are frameworks for modeling and solving decision problems that take into explicit account the effects of time. These formalisms are based on structural and semantical extensions of conventional decision models, e.g., decision trees and influence diagrams, with the mathematical definitions of finite-state semi-Markov processes. This paper identifies the common theoretical basis of existing dynamic decision modeling formalisms, and compares and contrasts their applicability and efficiency. It also argues that a subclass of such dynamic decision problems can be formulated and solved more effectively with non-graphical techniques. Some insights gained from this exercise on automating the dynamic decision …