Health Information Technology Commons^™

Information Systems And Health Care Xiii: Examining The Critical Requirements, Design Approaches And Evaluation Methods For A Public Health Emergency Response System, Ann L. Fruhling

Information Systems and Quantitative Analysis Faculty Publications

Research pertaining to emergency response systems has accelerated over the past few years, particularly since 9/11 events, and more recently due to Hurricane Katrina and concern over a potential of an avian flu pandemic. This study examines the requirements that are the most demanding with respect to software and hardware, and the associated design strategies for a public health emergency response system (ERS) for electronic laboratory diagnostics consultation. In addition, this study illustrates ways to evaluate the design decisions.

An important goal of a public health ERS is to improve the communication and notification of life-threatening diseases and harmful agents. …

Information Systems And Health Care Viii-Using Paper-Based Scenarios To Examine Perceptions Of Interactive Health Communication Systems, Nancy K. Lankton, Robert D. St. Louis

Accounting Faculty Research

While information and communication technologies can increase the health care provided to underserved populations, research concerning these technologies often involves only those patients who possess access to technology or who are otherwise willing and able to use it. This issue is important for both researchers and practitioners because non-users' beliefs may not only be different from users' beliefs, they may become more important to understand as access to technology increases. To address this problem: 1. We develop a model of the antecedents to perceived usefulness of an interactive health communication (IHC) system. While our research model combines health-related beliefs with …

Interdisciplinary Research And Publication Opportunites In Information Systems And Health Care, E. Vance Wilson, Nancy K. Lankton

Accounting Faculty Research

Healthcare is a large and growing industry that is experiencing major transformation in its information technology base. IS confronted similar transformations in other industries and developed theories and methods that should prove useful in healthcare applications. In turn, IS may benefit from incorporating knowledge from health informatics, a discipline that studies IT within medical and healthcare contexts. Despite the benefits, it is often a struggle for interdisciplinary researchers in IS and healthcare to publish their work, especially in journals directed toward IS audiences. In this paper, we outline strategies and resources to help ease this publication bottleneck. As a part …

Laboratory Automation Education, James D. Sterling

Business and Information Technology Faculty Research & Creative Works

No abstract provided.

Laboratory Automation Curriculum At Keck Graduate Institute, James D. Sterling

Business and Information Technology Faculty Research & Creative Works

A novel curriculum in laboratory automation and high-throughput technologies has been developed at the Keck Graduate Institute (KGI) over the past five years as part of the professional master's degree program in applied life sciences. The goal of this curriculum has been four-fold: (1) motivate study by describing the need for automation through several example problems in combinatorial biological discovery, (2) provide elements of fundamental engineering science that are required for the development of the technologies and tools that enable automation, (3) provide opportunities for the students to see and use state-of-the-art instruments, learn about existing industry standards, and to …

Resolution Of Multiple Ssdna Structures In Free Solution Electrophoresis, Eve F. Fabrizio, Ali Nadim, James D. Sterling

Business and Information Technology Faculty Research & Creative Works

By using high concentrations of buffer, electroosmotic flow within uncoated channels of a microfluidic chip was minimized, allowing the free solution electrophoretic separation of DNA. More importantly, because of the ability to efficiently dissipate heat within these channels, field strengths as high as 600 V/cm could be applied with minimal Joule heating (< 2 °C). As a result of the higher field strengths, separations within an 8-cm-long channel were achieved within a few minutes. However, when the electrophoretic separation of single-stranded DNA (ssDNA) less than 22 bases in length was performed, containing the fluorophore Texas Red as an end label, more than the expected single peak was observed at this high electric field. On the other hand, the free solution electrophoresis of a double-stranded DNA (dsDNA) consisting of a random sequence did exhibit the expected single peak. The appearance of these multiple peaks for ssDNA is shown to be dependent upon the base content and sequence of the ssDNA as well as on the chemical structure of the fluorophore used to tag the DNA for detection. Specifically, the peaks can be attributed to different secondary structures that result either from hydrophobic interactions between the DNA bases and an uncharged fluorescent dye or from G-quadruplexes within guanine-rich strands.

Sequence Dependent Mobility Of Short Oligonucleotides In Free-Solution Electrophoresis, James D. Sterling, Eve F. Fabrizio, Ali Nadim

Business and Information Technology Faculty Research & Creative Works

No abstract provided.

Method, Apparatus And Article For Microfluidic Control Via Electrowetting, For Chemical, Biochemical And Biological Assays And The Like, James D. Sterling

Business and Information Technology Faculty Research & Creative Works

An active-matrix microfluidic platform employs thin film transistor active ("TFT") matrix liquid crystal display ~ technology to manipulate small samples of fluid for chemical, biochemical, or biological assays without moving parts, for example, using a two-dimensional matrix array of drive electrodes. The active-matrix microfluidic platform may employ existing active matrix 0 addressing schemes and/or commercial "off-the-shelf" animation software to program assay protocols. A feedback subsystem may > determine an actual location of a fluid in the microfluidic structure, and provides location information to for display, for example, on an active-matrix display, and/or to control movement of one or more fluid bodies …

An International Cross-Cultural Study Of The Role Of Chief Informational Officers In Healthcare, Wallace Saunders

Faculty Dissertations

The introduction and utilization of Information Systems (IS) in the hospital environment has had a significant and lasting impact on the practice of medicine. The development of this dissertation will attempt to explore a widely overlooked area: The comparison of Chief Information Officers (CIOs) in the United States and the United Kingdom.

Aspects of CIO experiences relating to assumed roles, CIO challenges, skills, frustrations, success, failure, leadership, management, involvement and perceptions about the role of Information Technology (IT) in healthcare are discussed with a comparative global model. This study investigates the managerial roles of the Chief Information Officer based on …

A Lattice Boltzmann Subgrid Model For High Reynolds Number Flows, S. Hou, James D. Sterling, S. Chen, G. D. Doolen

Business and Information Technology Faculty Research & Creative Works

A sub grid turbulence model for the lattice Boltzmann method is proposed for high Reynolds number fluid flow applications. The method, based on the standard Smagorinsky sub grid model and a single-time relaxation lattice Boltzmann method, incorporates the advantages of the lattice Boltzmann method for handling arbitrary boundaries and is easily implemented on parallel machines. The method is applied to a two-dimensional driven cavity flow for studying dynamics and the Reynolds number dependence of the flow structures. The substitution of other sub grid models, such as the dynamic sub grid model, in the framework of the LB method is discussed.

Influence Of Formation Processes On Oblique Detonation Wave Stabilization, K. Ghorbanian, J. D. Sterling

Business and Information Technology Faculty Research & Creative Works

In this article we report steady, two-dimensional, inviscid solutions for the near field and far field of a supersonic reactive flow over a variable-double-ramp geometry. The incident shock wave compresses and heats the reactants that will combust after flowing some induction length. Upon reaction, a detonation wave forms and intersects the leading wave at some distance from the ramp surface. In this article, reaction-polar diagrams are developed, and the detonation branch solutions are used to investigate the wave interaction processes that may lead to a steady three-wave structure. By considering this formation process new oblique detonation wave stabilization criteria based …

Gas Dynamic Unstart In Superdetonative Ram Accelerators, Kaveh Ghorbanian, James D. Sterling

Business and Information Technology Faculty Research & Creative Works

In this paper we analyze the reflection of non-reacting shock waves as oblique detonation waves. The 2D, steady, inviscid analysis makes use of detonation polar diagrams to identify incident shock angles that lead to reflected detonations, with and without detonation Mach stem formation. The implications of the results for design and operation of superdetonative ram accelerators are explored. The influence of the projectile forebody geometry, the propellant composition, and the takeover velocity is described. We conclude with a discussion of the significance of these parameters on superdetonative ram accelerator unstart phenomena.

Enhanced Combustion Pulsejet Engines For Mach 0 To 3 Applications, J. Sterling, K. Ghorbanian, T. Sobota

Business and Information Technology Faculty Research & Creative Works

In this paper, we discuss the cyclic operation of an enhanced combustion pulsejet engine (ECPE) applicable in the Mach number range of 0 to 3. The geometry of this engine naturally provides for integration into a new combined cycle engine with ramjets. As in the operation of conventional pulsejets, an ECPE provides engine aspiration, charge compression, combustion and expansion without the use of turbomachinery. The use of modern electronics, fuel injection, and feedback control offers the potential for performance improvements that could make the ECPE a cost-effective competitor for the turbojet engine. This article describes the operating cycle of a …

Information Control And Security Policy In Health Care Information Systems, Binshan Lin, Lawrence Clark

Journal of International Information Management

The reliance on information systems forces the health care organizations to consider two security management issues: information control and security policy. The objective of this article is to examine a direction to effectively support and enhance the health care delivery through information systems in hospitals. An integrated focus is provided through an information control framework for analyzing the three control elements: accessibility, confidentiality, and integrity. The security policy involves three aspects: prevention of unauthorized access into the system, controlling the input and output of the system, and monitoring the health care information systems. The framework has implications for research beyond …

Health Care Information Systems Management: Structure And Infrastructure, Binshan Lin

Journal of International Information Management

The practice of medicine is inextricably entwined with the management of health care information system (HCIS). Major problems with HCIS are that it has not evolved from the needs of end users, and lacks of an organizational base^ to manage the HCIS in the health care environment. The object of this paper is to examine a direction to effectively support and enhance the health care activities through managing HCIS. An integrated focus is provided through a framework for analyzing the structure and infrastructure of HCIS in hospitals.

Applying A Systems Approach To Mis Design For Occupational Health Care Delivery, Charmayne Cullom

Journal of International Information Management

Decision making in occupational health care management is complex due to the various parties involved in receiving, delivering, and/or paying for^ these services. This paper presents the view of MIS to support occupational health care as a system using Anthony's Paradigm to provide the decision making structure. Informational requirements reflect the hierarchy of strategic, tactical, and operational levels. A matrix of occupational health care services, responsibilities, and participants is utilized. Such matrix provides the foundation to couple needs and requirements of all participants with information system specifications.

Lattice Boltzmann Thermohydrodynamics, F. J. Alexander, S. Chen, J. D. Sterling

Business and Information Technology Faculty Research & Creative Works

We introduce a lattice Boltzmann computational scheme capable of modeling thermohydrodynamic flows of monatomic gases. The parallel nature of this approach provides a numerically efficient alternative to traditional methods of computational fluid dynamics. The scheme uses a small number of discrete velocity states and a linear, single-time relaxation collision operator. Numerical simulations in two dimensions agree well with exact solutions for adiabatic sound propagation and Couette flow with heat transfer. © 1993 The American Physical Society.