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In Vitro Bioactivities Of Single Or Combined Extracts From Three Selected Asian Vegetables, Mahmud Norfaizah
In Vitro Bioactivities Of Single Or Combined Extracts From Three Selected Asian Vegetables, Mahmud Norfaizah
Student Works (2020-2029)
Three underutilized folklore oriental-based vegetables Acalypha indica (AI), Centella asiatica (CA), and Sesbania grandiflora (SG) have been investigated for pharmacological activities relevant to wound healing process and synergistic actions. Single and combination of aqueous (A) and methanol (M) extracts of the three vegetables namely AI-A, CA-A, SG-A, AI-M, CA-M, SG-M, AI-A+CA-A, AI-A+SG-A, CA-A+SG-A, AI-M+CA-M, AI-M+SG-M, and CA-M+SG-M were assessed for stimulation of wound closure by normal human dermal fibroblast (NHDF) cells, antioxidant, protection against hydrogen peroxide (H2O2), stimulation of nitric oxide (NO) from RAW264.7 macrophages and antimicrobial activities. The combined vegetable extracts AI-A+CA-A (90.76%) showed the highest percentage of wound …