Wounds and Injuries Commons^™

Investigating Extracellualr Vesicles Role In The Pathogenesis Of Acute Lung Injury, Ruben Manuel Luciano Colunga Biancatelli, Pavel Solopov, Tierney Day, Anca Dobrian, John D. Catravas

Cardiovascular Research Symposium

Background: Extracellular vesicles (EVs) are small lipid-bound particles containing proteins and RNAs, whose role in intercellular communication and signaling is critical for homeostasis or inflammatory responses. Patients with acute lung injury display changes in EVs number, cargo content and signature compared to healthy individuals.

Hypothesis: We have hypothesized that EVs may play a role in the pathogenesis of acute lung, by transferring harmful mediators of inflammation and disrupting recipient cells homeostasis.

Methods: C57BL/6j mice (8-10 weeks old, 25g BW) were intratracheally instilled with 50µL of 5*1010- 11 EVs isolated from Human Lung Microvascular Endothelial cells (HLMVEC) exposed to 1 µg …

Immediate Effect Of Heel-Pain Orthosis And An Augmented Low-Dye Taping On Plantar Pressures And Pain In Subjects With Plantar Fasciitis, Tracy Andus

Human Movement Studies & Special Education Theses & Dissertations

Research has been done investigating plantar pressures and pain in subjects with pathologies after the application of orthoses and arch taping. To date, however, no study has been conducted investigating plantar pressures and pain in subjects with plantar fasciitis after the application of the augmented low-dye taping (ALD) in comparison to a heel-pain orthosis (HPO). Therefore, the purpose of this study was to determine the effects of the ALD in comparison to a HPO on pain, peak plantar pressure (PPP), and mean plantar pressure (MPP) under multiple areas of the foot in subjects with plantar fasciitis while walking and jogging. …

An Assessment Of An Education Intervention On Youth Sports Coaches Knowledge Of Concussions, Heidi Elizabeth Brigham

Human Movement Studies & Special Education Theses & Dissertations

Research has shown that sport related concussions are occurring at high rates across the United States. Research has also shown that there are many misconceptions among youth sports coaches regarding concussions. Therefore the purpose of this study was to determine the effects of an educational intervention on the knowledge of concussion recognition, management and prevention for youth sports coaches. A secondary purpose was to compare various relationships between demographic characteristics and the concussion knowledge assessment scores. A twenty-one question multiple choice assessment and 16 option symptom recognition checklist was utilized to assess concussion knowledge prior to and following an educational …

The Effects Of A Short Course Of Muscle Energy Technique On Sacral Dysfunction In Patients With Acute Lumbosacral Pain, Regina O'Hara

Human Movement Studies & Special Education Theses & Dissertations

The purposes of this research study were to examine the effects of treating patients with suspected acute iliosacral rotational dysfunction with muscle energy techniques (MET) on (1) disability, (2) perceived pain during lumbar motion in neutral, flexion, and extension, (3) lumbar range of motion in flexion and extension, and (4) sagittal innominate rotation. Subjects were randomly assigned to the experimental and placebo groups. Experimental subjects received MET treatments, and placebo subjects received a stretching placebo treatinent. Subjects were treated four times over the course of one week. The initial examination and treatment occurred within 72 hours of the onset of …

An Assessment Of High School Coaches Knowledge Of Sport-Related Concussion, Erin M. O'Donoghue

Human Movement Studies & Special Education Theses & Dissertations

Sport-related concussion is a common occurrence in high-risk sports and can occur during participation in all sports. The purpose of this study was to assess the knowledge base high school athletic coaches possess about concussion signs and symptoms in regards to recognition, management, and prevention of this condition. A 25 question demographic questionnaire was used to gather background information and a 24 question multiple-choice assessment was used to determine knowledge of recognition, management, and prevention of sport-related concussion. A panel of eight experts in the fields of sport-related concussion and/or survey research reviewed and modified the survey instrument, which were …

The Short-Term Effects Of Grade 1 And 2 Joint Mobilizations On Subject Pain Range Of Motion And Muscle Activity In The Pathological Lumbar Spine, Sean Hanrahan

Human Movement Studies & Special Education Theses & Dissertations

The purpose of this study was to examine the short-term effects of Grades 1 and 2 posteroanterior joint mobilizations (JM) at the pathological lumbar spine on subject pain, range of motion (ROM), and muscle force. All subjects were determined to have sustained mechanical dysfunction of the lumbar spine of less than 48 hours as assessed through a standardized evaluation. Subjects were randomly assigned to a group; the control group received ice and stretching while the experimental group received JM in addition to ice and stretching. The JM's were performed at 3 consecutive lumbar segments surrounding the area of greatest discomfort. …

The Effect Of Occupant And Vehicular Parameters On The Onset And Severity Of Whiplash Associated Disorder, James Keith Wilkerson

Human Movement Studies & Special Education Theses & Dissertations

Whiplash Associated Disorder (WAD) cases millions of injuries and billions of dollars in litigation and medical cost. The purpose of this study was to determine if any relationship existed between certain occupant and vehicular constants and the onset and severity of WAD. One hundred subjects involved in low-speed collisions were selected from an active database. Fifty-nine subjects were females and 70% of the subjects were drivers. A discriminant function analysis was performed, with occupant position and duration as the only variables that had significant discriminating power. However, eighty-four percent of the subjects experienced 100millisecond accelerations and 70% were drivers. Therefore, …