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Full-Text Articles in Skin and Connective Tissue Diseases

The Ninth Chondroid Syringoma With Bone Formation: A Case Report, Mojan Deriss, Kelsey Ouyang, Parnian Alizadeh, Amir Qorbani, Voicu S. Ciobanu Feb 2026

The Ninth Chondroid Syringoma With Bone Formation: A Case Report, Mojan Deriss, Kelsey Ouyang, Parnian Alizadeh, Amir Qorbani, Voicu S. Ciobanu

Annual Research Symposium

This poster presents a rare case of chondroid syringoma with ossification, representing only the ninth reported instance of bone formation within this adnexal tumor. The report describes a slowly enlarging facial nodule in a 34-year-old male, detailing clinical presentation, surgical excision, and histopathologic findings. Microscopy revealed characteristic epithelial cords and tubules within a myxoid stroma, along with mature lamellar bone formation, confirming the diagnosis. The case expands the known morphologic spectrum of chondroid syringomas and highlights the importance of considering this entity in the differential diagnosis of benign facial masses, particularly when unusual features such as ossification are present.


Stroke To Spread: Pachymeningeal Carcinomatosis In A 40-Year-Old With Metastatic Breast Cancer Confirmed Via Dural Biopsy, Aneesha Shaju, Thomas K. Hoang, Grace Desrochers, Woondong Jeong Jan 2026

Stroke To Spread: Pachymeningeal Carcinomatosis In A 40-Year-Old With Metastatic Breast Cancer Confirmed Via Dural Biopsy, Aneesha Shaju, Thomas K. Hoang, Grace Desrochers, Woondong Jeong

Gulf Coast Division GME Research Day 2026

No abstract provided.


Bilateral Pseudoangiomatous Stromal Hyperplasia In A Twelve-Year-Old Female: A Case Report, Alexandra Mcmillan, Taylor Sullivan, Joyce Moore, Robert M. Pride Jan 2026

Bilateral Pseudoangiomatous Stromal Hyperplasia In A Twelve-Year-Old Female: A Case Report, Alexandra Mcmillan, Taylor Sullivan, Joyce Moore, Robert M. Pride

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.


A Case Report Of A Rare Skin Lesion: Malignant Or Benign?, Anila Punjwani, Shane Sweeney, Pierre Khoury, Mike Liang Jan 2026

A Case Report Of A Rare Skin Lesion: Malignant Or Benign?, Anila Punjwani, Shane Sweeney, Pierre Khoury, Mike Liang

Gulf Coast Division GME Research Day 2026

No abstract provided.


Long-Term Incidence Trends And Stage Distribution Of Cutaneous Melanoma In The United States (1975–2022): A Seer Population-Based Analysis, Thea Danielle Amadasun, Shahzaib Maqbool Jan 2026

Long-Term Incidence Trends And Stage Distribution Of Cutaneous Melanoma In The United States (1975–2022): A Seer Population-Based Analysis, Thea Danielle Amadasun, Shahzaib Maqbool

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.


Investigating The Role Of Traditional Chinese Herbal Medicine For Cancer Symptom Management In Older Adults: A Rapid Review, Isabelle C. Karshner Jan 2026

Investigating The Role Of Traditional Chinese Herbal Medicine For Cancer Symptom Management In Older Adults: A Rapid Review, Isabelle C. Karshner

Honors Undergraduate Theses

Background: Patients with cancer often experience symptoms related to disease, complications, and treatment. One potential method of alleviating these symptoms is traditional Chinese herbal medications (TCHM). This rapid review explores the role of traditional Chinese herbal medications in treating cancer-related symptoms in older adults.

Purpose: The purpose of this rapid review is to gain and provide a better understanding of the effects of TCHM on cancer-symptom management in the older adult population. This review explores the association between TCHM and effects on cancer symptoms in older adults, including interactions, toxicity, and signs/symptoms of TCHM use that may be useful information …


High-Grade Undifferentiated Sarcoma With Osteoclast-Like Giant Cells Mimicking A Pyogenic Granuloma, Shiv Patel, Tamara Fakhoury, Taha Rasul, Benjamin Cooper, Leila Parsa, Madeline Coleman, Alexandra Mathis, Karthik Krishnamurthy, Michelle Foley Jan 2026

High-Grade Undifferentiated Sarcoma With Osteoclast-Like Giant Cells Mimicking A Pyogenic Granuloma, Shiv Patel, Tamara Fakhoury, Taha Rasul, Benjamin Cooper, Leila Parsa, Madeline Coleman, Alexandra Mathis, Karthik Krishnamurthy, Michelle Foley

South Atlantic Division GME Research Days 2026

No abstract provided.


Afx: Small Tumor, Big Personality, Alexandra Mathis, Abigail Lowe, Juan Rosario Jan 2026

Afx: Small Tumor, Big Personality, Alexandra Mathis, Abigail Lowe, Juan Rosario

South Atlantic Division GME Research Days 2026

No abstract provided.


Not Your Average Nodule: The Enigmatic Chondroid Syringoma, Alexandra Mathis, Clara Barranco, Joanna Mcgetrick, Karthik Krishnamurthy Jan 2026

Not Your Average Nodule: The Enigmatic Chondroid Syringoma, Alexandra Mathis, Clara Barranco, Joanna Mcgetrick, Karthik Krishnamurthy

South Atlantic Division GME Research Days 2026

No abstract provided.


A Colonic Metastasis Of Breast Cancer Discovered During Routine Surveillance Colonoscopy: A Rare Case Report, Minh Nguyen, Brenden Pearce, Jayden Navarro, Brooke Escoe, Kathleen Raynor Jan 2026

A Colonic Metastasis Of Breast Cancer Discovered During Routine Surveillance Colonoscopy: A Rare Case Report, Minh Nguyen, Brenden Pearce, Jayden Navarro, Brooke Escoe, Kathleen Raynor

South Atlantic Division GME Research Days 2026

No abstract provided.


A Rare Case Of Severe Disseminated Pyoderma Gangrenosum Of The Upper Body With Concurrent Nasopharyngeal And Inferior Orbital Wall Necrosis, Robert M. Branstetter, Isabel E. Baird, Mohammed S. Rais, Danielle N. Ledet, Megan N. Terrebonne Dec 2025

A Rare Case Of Severe Disseminated Pyoderma Gangrenosum Of The Upper Body With Concurrent Nasopharyngeal And Inferior Orbital Wall Necrosis, Robert M. Branstetter, Isabel E. Baird, Mohammed S. Rais, Danielle N. Ledet, Megan N. Terrebonne

School of Medicine Faculty Publications

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis usually linked to autoimmune or inflammatory bowel disease and typically affects the lower extremities. This case is notable for extensive upper-body, oropharyngeal, and nasal involvement in a patient without an underlying autoimmune disorder. A 56-year-old man with chronic cocaine use and stage IV renal cell carcinoma presented with rapidly progressive ulcerations of the face, neck, shoulders, and back, along with nasal septal collapse and oropharyngeal destruction. Prior biopsy demonstrated sterile neutrophilic inflammation without vasculitis, infection, or malignant infiltration, supporting PG as a diagnosis of exclusion. Imaging showed erosive sinonasal disease. He was …


Decreased Risk Of Incident Cancer Among Patients With Vitiligo: A Multicenter Retrospective Cohort Analysis, Rahib K. Islam, Ivan D. Nguyen, Kazi N. Islam, Lacey M. Falgout, Jonathan M. Joseph, Collins T. Langley, Christopher J. Haas Sep 2025

Decreased Risk Of Incident Cancer Among Patients With Vitiligo: A Multicenter Retrospective Cohort Analysis, Rahib K. Islam, Ivan D. Nguyen, Kazi N. Islam, Lacey M. Falgout, Jonathan M. Joseph, Collins T. Langley, Christopher J. Haas

School of Medicine Faculty Publications

No abstract provided.


Efficacy And Safety Of Rigosertib In Patients With Recessive Dystrophic Epidermolysis Bullosa-Associated Advanced/Metastatic Cutaneous Squamous Cell Carcinoma, Martin Laimer, Andrew P. South, Elisabeth Mayr, Sophie Kitzmueller, Lauren Banner, Michael Alexander, Linda Hosler, Henry Yang, Matthew Parris, Meena Arora, Georg Zimmermann, Gregor Schweighofer-Zwink, Johann Bauer, Neda Nikbakht Sep 2025

Efficacy And Safety Of Rigosertib In Patients With Recessive Dystrophic Epidermolysis Bullosa-Associated Advanced/Metastatic Cutaneous Squamous Cell Carcinoma, Martin Laimer, Andrew P. South, Elisabeth Mayr, Sophie Kitzmueller, Lauren Banner, Michael Alexander, Linda Hosler, Henry Yang, Matthew Parris, Meena Arora, Georg Zimmermann, Gregor Schweighofer-Zwink, Johann Bauer, Neda Nikbakht

Department of Dermatology and Cutaneous Biology Faculty Papers

BACKGROUND: Recessive dystrophic epidermolysis bullosa (RDEB) is an epithelial fragility disease primarily affecting the skin and is caused by variants in the COL7A1 gene. Individuals with RDEB are predisposed to develop highly aggressive cutaneous squamous cell carcinomas (SCCs) which are the most common cause of premature death. There is a lack of effective prevention or treatment options for patients with RDEB-SCC.

OBJECTIVES: To evaluate the antitumour activity and safety of the polo-like kinase-1 (PLK1) inhibitor, rigosertib, two investigator-initiated open-label, single-arm phase II studies were opened in Europe and the USA and enrolled five patients with RDEB diagnosed with locally advanced …


Breast Reconstruction In Becker Nevus Syndrome, Alexis K. Schlosser, Mohammed S. Rais, Ruston J. Sanchez Jul 2025

Breast Reconstruction In Becker Nevus Syndrome, Alexis K. Schlosser, Mohammed S. Rais, Ruston J. Sanchez

School of Medicine Faculty Publications

Becker nevus syndrome is a rare cutaneous disorder characterized by the presence of a hyperpigmented patch of skin typically occurring on the upper trunk, often associated with hypertrichosis, and sometimes associated with musculoskeletal abnormalities ipsilateral to the nevus. Becker nevus syndrome can lead to breast hypoplasia. Unlike other forms of breast hypoplasia, treatment should begin before the completion of breast development. Due to the rarity of the disease, breast reconstruction in these patients has no gold-standard approach, and treatment is often delayed. Therefore, our case report highlighted the need for early treatment and provided options for reconstruction in this population. …


Photodynamic Therapy Vs. 5-Fluorouracil For Field-Directed Treatment Of Actinic Keratosis: A Comparative Literature Review, Bhumik Patel May 2025

Photodynamic Therapy Vs. 5-Fluorouracil For Field-Directed Treatment Of Actinic Keratosis: A Comparative Literature Review, Bhumik Patel

Rowan-Virtua Research Day

BACKGROUND: Actinic keratosis (AK) is a common precancerous skin condition arising from chronic UV exposure and often involves field cancerization, where visible lesions coexist with subclinical damage. Effective field-directed treatments are critical for preventing progression to squamous cell carcinoma.

HYPOTHESIS: Photodynamic Therapy (PDT) may offer superior efficacy, cosmetic outcomes, and patient adherence compared to topical 5-Fluorouracil (5-FU), despite its higher cost and clinical setting requirement.

METHODS: This literature review analyzed peer-reviewed studies from 2015–2025 comparing PDT and 5-FU for field-directed AK treatment. Outcomes assessed included lesion clearance, recurrence, tolerability, adherence, cost, and patient satisfaction.

RESULTS: PDT demonstrated high clearance rates …


A Case Of Carcinoma En Cuirasse, Nadeen Gonna, Giancarlo Moscol, Woo Cheal Cho, Constance T. Albarracin, Hung Q. Doan Jan 2025

A Case Of Carcinoma En Cuirasse, Nadeen Gonna, Giancarlo Moscol, Woo Cheal Cho, Constance T. Albarracin, Hung Q. Doan

Gulf Coast Division GME Research Day 2025

No abstract provided.


Skin Cancer Education For Adolescents: Does Vanity Modify Its Effectiveness?, Erica Ogwumike, Dina Zamil, Harrison Zhu, Shangyi Fu, Emily Powell, Zeena Nawas, Ida Orengo Jan 2025

Skin Cancer Education For Adolescents: Does Vanity Modify Its Effectiveness?, Erica Ogwumike, Dina Zamil, Harrison Zhu, Shangyi Fu, Emily Powell, Zeena Nawas, Ida Orengo

Gulf Coast Division GME Research Day 2025

No abstract provided.


Improving Skin Cancer Screening In A Fm Residency: Dermatoscope Utilization, Aleksandra Radzio, Navina Delight, Aniruddha Logan Jan 2025

Improving Skin Cancer Screening In A Fm Residency: Dermatoscope Utilization, Aleksandra Radzio, Navina Delight, Aniruddha Logan

North Florida Division GME Research Day 2025

No abstract provided.


A Complex Case Of Invasive Ductal Carcinoma In A Patient With Multisystem Complications Leading To Acute Cerebral Infarctions And Debility, Genevieve Mccloskey, Radhika Mohan, Michael A. Smith Jan 2025

A Complex Case Of Invasive Ductal Carcinoma In A Patient With Multisystem Complications Leading To Acute Cerebral Infarctions And Debility, Genevieve Mccloskey, Radhika Mohan, Michael A. Smith

South Atlantic Division GME Research Day 2025

No abstract provided.


Cryptococcoid Sweet Syndrome Following Carcinoid Tumor Removal, Ashlyn Fletcher, Taylor Smith Jan 2025

Cryptococcoid Sweet Syndrome Following Carcinoid Tumor Removal, Ashlyn Fletcher, Taylor Smith

South Atlantic Division GME Research Day 2025

No abstract provided.


Atypical Presentation Of Eruptive Syringomas On The Forearms Of A 19-Year-Old Patient, Margo Waters, Sami Osman, Jacob Hostetter, Joy Mosser-Goldfarb Jan 2025

Atypical Presentation Of Eruptive Syringomas On The Forearms Of A 19-Year-Old Patient, Margo Waters, Sami Osman, Jacob Hostetter, Joy Mosser-Goldfarb

West Florida Division GME Research Day 2025

No abstract provided.


Perceived Risk Of Skin Cancer: Influence Of Family History, Age, Ethnicity, And Fitzpatrick Type, Henry Lim, Reem Ayoub, Rafael Do Valle, Kristina Kafle, Dana Olsen, Ysabelle Martinez, Christina Guo, Marshall Hall, Christian Scheufele, Michael Carletti, Stephen Weis Jan 2025

Perceived Risk Of Skin Cancer: Influence Of Family History, Age, Ethnicity, And Fitzpatrick Type, Henry Lim, Reem Ayoub, Rafael Do Valle, Kristina Kafle, Dana Olsen, Ysabelle Martinez, Christina Guo, Marshall Hall, Christian Scheufele, Michael Carletti, Stephen Weis

North Texas Research Forum 2025

Background: Skin cancer in the United States accounts for approximately 50% of new early cancer diagnoses. Despite this, many individuals underestimate their personal risk, leading to lower engagement in preventative behaviors. Several factors may influence an individual’s perceived risk, including family history, age, race, ethnicity, skin type, and gender. While some individuals recognize their increased susceptibility based on personal, familial, and cultural experiences, others may have a lower perceived risk due to misconceptions or limited awareness. This study examines how these demographic factors influence individuals' perceived risk of skin cancer. Methods: This study analyzed data from 333 individuals aged 19 …


Diagnosis Of Hibernoma: A Case Report Of A Benign Adipose Tumor With Radiological And Histopathological Features, Pavan Patel, Himani Patel, Patrick Mullinix Jan 2025

Diagnosis Of Hibernoma: A Case Report Of A Benign Adipose Tumor With Radiological And Histopathological Features, Pavan Patel, Himani Patel, Patrick Mullinix

South Atlantic Division GME Research Day 2025

No abstract provided.


Don’T Sweat It: A Case Of Solid Cystic Hidradenoma, Anthony Concilla, Michelle Militello, Angelia Stepien, Juan Rosario-Collazo Jan 2025

Don’T Sweat It: A Case Of Solid Cystic Hidradenoma, Anthony Concilla, Michelle Militello, Angelia Stepien, Juan Rosario-Collazo

South Atlantic Division GME Research Day 2025

No abstract provided.


Dermoscopic Features Of Sebaceous Adenoma, Abigail M. Lowe, Michelle Militello, Karthik Krishnamurthy, Sarah Ferrer-Bruker Jan 2025

Dermoscopic Features Of Sebaceous Adenoma, Abigail M. Lowe, Michelle Militello, Karthik Krishnamurthy, Sarah Ferrer-Bruker

South Atlantic Division GME Research Day 2025

No abstract provided.


Targeted Therapies And Parpi Therapy Response Following Ici Therapy Failure In Advanced Melanoma, George Nassief, Renee Morecroft, Jordan Phillipps, David Chen, George Ansstas Jan 2025

Targeted Therapies And Parpi Therapy Response Following Ici Therapy Failure In Advanced Melanoma, George Nassief, Renee Morecroft, Jordan Phillipps, David Chen, George Ansstas

South Atlantic Division GME Research Day 2025

No abstract provided.


Eccrine Carcinomas And Homologous Recombination Repair Cancer Predisposition Genes: A Case Series, Renee Morecroft, Jordan Phillipps, Kaiden Barodinksy, Susan Jones, Lulu Sun, Danielle Crites, Omar Butt, George Ansstas, Patrick Grierson Jan 2025

Eccrine Carcinomas And Homologous Recombination Repair Cancer Predisposition Genes: A Case Series, Renee Morecroft, Jordan Phillipps, Kaiden Barodinksy, Susan Jones, Lulu Sun, Danielle Crites, Omar Butt, George Ansstas, Patrick Grierson

South Atlantic Division GME Research Day 2025

No abstract provided.


More Than Skin Deep: A Long Term Cyst Masquerades Breast Cancer Metastasis, Paola Torres-Laboy, Juan Rosario Collazo Jan 2025

More Than Skin Deep: A Long Term Cyst Masquerades Breast Cancer Metastasis, Paola Torres-Laboy, Juan Rosario Collazo

South Atlantic Division GME Research Day 2025

No abstract provided.


Comparison Of Predicted And Actual Dermatitis Generated From Computed Tomography Images And Dose Distribution Maps, Yasuhide Miyabe, Saori Oshiro, Hiroto Seki, Yusuke Muroi, Eriko Kawashima, Megumi Hosoda, Kento Ohashi, Hiromu Yamanaka, Mingliang Shao, Hiromi Sugawara, Jyunetsu Mizoe, Ritsuko Komaki Dec 2024

Comparison Of Predicted And Actual Dermatitis Generated From Computed Tomography Images And Dose Distribution Maps, Yasuhide Miyabe, Saori Oshiro, Hiroto Seki, Yusuke Muroi, Eriko Kawashima, Megumi Hosoda, Kento Ohashi, Hiromu Yamanaka, Mingliang Shao, Hiromi Sugawara, Jyunetsu Mizoe, Ritsuko Komaki

Faculty, Staff and Students Publications

Anticipating the onset, location and severity of radiation dermatitis before radiotherapy can aid in dermatological care. This study developed a method for creation of a prediction diagram for dermatitis and conducted a comparative verification between the prediction diagram and actual patient condition. The prediction diagram involved converting skin doses into 2 Gy fractionated equivalent doses using α/β of 10.0, defining regions of interest (ROIs) from 20-50 Gy at 10 Gy intervals. Overlaps between these ROIs at each dose level and the skin (external) was sequentially color-coded as blue, yellow, red, and purple. The study included four patients: two underwent head …


Genetic Analysis Of Kmt2d Loss In Tumorigenesis Using Genetically Engineered Mouse Models, Yingda Jiang Aug 2024

Genetic Analysis Of Kmt2d Loss In Tumorigenesis Using Genetically Engineered Mouse Models, Yingda Jiang

Dissertations and Theses (Open Access)

The Cancer Genome Atlas Program (TCGA) has discovered multiple tumor suppressors that are commonly mutated across a variety of human cancers, such as chromatin regulators in COMPASS and SWI/SNF complexes. KMT2D, a histone H3K4 methyltransferase in the COMPASS complex, is frequently mutated in human lymphoma, melanoma, and epithelial carcinoma. Biochemically, KMT2D shapes the cellular enhancer landscape as the major writer of the putative enhancer mark H3K4me1. Given the critical role of cellular enhancer landscape in determining cellular lineage in embryonic development, it is unknown whether enhancer dysregulation caused by KMT2D loss leads lineage switch of tumor cells, which has …