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Respiratory Tract Diseases Commons

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Virus Diseases

2020 Symposium Posters

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Literature Review Of Covid-19 Biochemistry, Alexandra Allen Jan 2020

Literature Review Of Covid-19 Biochemistry, Alexandra Allen

2020 Symposium Posters

SARS-CoV-2 is the virus responsible for the current pandemic. SARS-CoV-2 is a betacoronavirus with a genome that is 79.5% identical to SARS-CoV. The virus enters T lymphocytes using its spike protein with the human angiotension-converting enzyme 2 as its receptor. SARS-CoV-2 was found to have a unique peptide sequence that could contribute to the proteolytic cleavage of the spike protein, therefore potentially impacting host range and transmissibility. COVID-19 is diagnosed through a nasal swab SARS-CoV-2 RT-PCR assay and the most common symptoms appear to be fever, cough, and fatigue. The median amount of time an individual will be contagious with …