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- Parkinson's disease (2)
- Computer-generated graphical tool (1)
- Displacement perception (1)
- Functional Brain Connectivity (1)
- Graph Analysis (1)
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- Levodopa (1)
- Minimum Spanning Tree (1)
- Parkinsonian hand tremor (1)
- Resting-state EEG (1)
- Single-input-multiple-output mechanism (1)
- Temporal perception (1)
- Tremor assessment (1)
- Tremor estimation (1)
- Tremor suppression glove (1)
- Velocity perception (1)
- Visual non-motor symptoms (1)
- Wearable device (1)
Articles 1 - 3 of 3
Full-Text Articles in Nervous System Diseases
Effect Of Levodopa On Eeg Connectivity In Parkinson's Patients, Sepehr Torab Parhiz
Effect Of Levodopa On Eeg Connectivity In Parkinson's Patients, Sepehr Torab Parhiz
Electronic Thesis and Dissertation Repository
Levodopa is a dopamine replacement medication administered to patients with Parkinson’s disease (PD) to alleviate their motor symptoms. However, its long-term use can cause adverse side effects, including involuntary motor movements. We studied 16 PD patients before and after taking Levodopa based on resting-state electroencephalography (EEG) recordings to determine how Levodopa affects the functional connectivity of their brain networks. We used several metrics from graph theory, in particular the minimum spanning tree (MST) metric, and analyzed how they change after subjects take Levodopa. We observed significant changes in the lower alpha band toward a more path-like and less globally efficient …
Investigation Of Visual Perceptions In Parkinson's Disease And The Development Of Disease Monitoring Software, Matthew Bernardinis
Investigation Of Visual Perceptions In Parkinson's Disease And The Development Of Disease Monitoring Software, Matthew Bernardinis
Electronic Thesis and Dissertation Repository
Non-motor Parkinson’s Disease (PD) symptoms are substantial factors of PD arising throughout disease stages, yet their diagnosis and monitoring remain a challenge. Sensory abnormalities in PD occur across sensory systems and disease stages, contributing to disease-related impairments. However, the extent of symptoms is unknown, with inadequate monitoring and treatment options furthering disease management difficulties. The current work studies movement-independent visual perceptions of time, displacement and velocity in PD patients across disease stages using levodopa, deep brain stimulation (DBS), or no PD therapy. Perceptual tasks were conducted using a computer-generated graphical device designed with a focus on simplicity and flexibility. Perception …
Towards The Development Of A Wearable Tremor Suppression Glove, Yue Zhou
Towards The Development Of A Wearable Tremor Suppression Glove, Yue Zhou
Electronic Thesis and Dissertation Repository
Patients diagnosed with Parkinson’s disease (PD) often associate with tremor. Among other symptoms of PD, tremor is the most aggressive symptom and it is difficult to control with traditional treatments. This thesis presents the assessment of Parkinsonian hand tremor in both the time domain and the frequency domain, the performance of a tremor estimator using different tremor models, and the development of a novel mechatronic transmission system for a wearable tremor suppression device. This transmission system functions as a mechatronic splitter that allows a single power source to support multiple independent applications. Unique features of this transmission system include low …