Eye Diseases Commons^™

Efficient In Vitro Development Of Photoreceptors From Human Pluripotent Stem Cells, Joseph C. Reynolds

Dissertations, Masters Theses, Capstones, and Culminating Projects

Degeneration of the rod and cone photoreceptors in the human retina is among the most common causes of blindness. Replacing these damaged photoreceptors may help to restore vision. Repairing the damaged retina relies on the insertion of new, healthy cells. Embryonic stem (ES) cells and induced pluripotent stem (iPS) cells are two possible sources of photoreceptors to restore vision. Previous data shows that human ES cells and iPS cells can be differentiated into photoreceptors and transplanted into the eye to restore some vision. However, this process is inefficient, and costly. Here, we show a new method for inducing photoreceptor production …

The Rehabilitative Potential Of Auditory To Visual Sensory Substitution Devices For The Blind, Naomi Perl

The Science Journal of the Lander College of Arts and Sciences

Living with a sensory impairment is challenging, and those who have lost the use of one sensory modality need to find ways to deal with numerous problems encountered in daily life. When vision is lost, these challenges include navigation through space, finding objects, recognizing people or surroundings, reading or even communicating without access to nonverbal signs provided by others such as eye gaze or facial expressions. Nevertheless, the blind manage to function efficiently in their environment, often to a surprisingly high degree. The key to this amazing phenomenon lies in the plasticity of the brain and the connections it makes …

Is Bevacizumab Effective In Inhibiting The Growth Of Recurrent Pterygium?, Sharon L. De La Cruz

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not Bevacizumab is an effective treatment in inhibiting the growth of recurrent pterygium.

Study Design: Review of three published, English language randomized controlled trials published in 2010, 2012, and 2013.

Data Sources: Three randomized controlled trials measuring the efficacy of Bevacizumab to inhibit the growth of recurrent pterygium were found using PubMed and OVID databases.

Outcome(s) Measured: The severity and progression of pterygium recurrence as well as corneal neovascularization were the main outcomes measured. Conjunctival injection, thickness, and size of the fibrovascular tissue were examined in subjects …