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Full-Text Articles in Cardiovascular Diseases
Drug-Induced Nutrient Depletion, Rodney Richmond
Drug-Induced Nutrient Depletion, Rodney Richmond
College of Pharmacy Faculty Research and Publications
No abstract provided.
Molecular Basis Of Sex Differences In Cardiac Hypertrophy And Heart Failure, Maya James
Molecular Basis Of Sex Differences In Cardiac Hypertrophy And Heart Failure, Maya James
Online Theses and Dissertations
Transforming growth factor beta ligands and receptors are known to be pro-hypertrophic and pro-fibrotic factors in the heart, and are known to contribute to the development of cardiac hypertrophy and heart failure. It is well established that premenopausal females possess a lower incidence of these pathologies. We and others have observed a greater level of fibrosis in male hearts compared to female hearts in rodent models of cardiac hypertrophy. It is well established that estrogen is cardioprotective in that it can prevent the development of cardiac hypertrophy, as well as abrogate the development of heart failure following sustained cardiac hypertrophy. …