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Cardiovascular Diseases Commons

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Full-Text Articles in Cardiovascular Diseases

Nanomaterials As Novel Cardiovascular Theranostics, Rajasekharreddy Pala, Subhaswaraj Pattnaik, Siddhardha Busi, Surya M. Nauli Mar 2021

Nanomaterials As Novel Cardiovascular Theranostics, Rajasekharreddy Pala, Subhaswaraj Pattnaik, Siddhardha Busi, Surya M. Nauli

Pharmacy Faculty Articles and Research

Cardiovascular diseases (CVDs) are a group of conditions associated with heart and blood vessels and are considered the leading cause of death globally. Coronary heart disease, atherosclerosis, myocardial infarction represents the CVDs. Since CVDs are associated with a series of pathophysiological conditions with an alarming mortality and morbidity rate, early diagnosis and appropriate therapeutic approaches are critical for saving patients’ lives. Conventionally, diagnostic tools are employed to detect disease conditions, whereas therapeutic drug candidates are administered to mitigate diseases. However, the advent of nanotechnological platforms has revolutionized the current understanding of pathophysiology and therapeutic measures. The concept of combinatorial therapy …


Untrained Volunteers Are Marginally Effective In Delivering Public Access Defibrillation, Richard N. Bradley, Lynda J. Schoenstein, Mohhamad Alshanti Oct 2000

Untrained Volunteers Are Marginally Effective In Delivering Public Access Defibrillation, Richard N. Bradley, Lynda J. Schoenstein, Mohhamad Alshanti

Richard N Bradley

Study objectives: This study analyzed the behavior of untrained volunteers when presented with a simulated cardiac arrest and an automated external defibrillator (AED). The primary hypothesis of this study was that volunteers could, with no advance training, operate an AED to deliver a defibrillation to a mannequin in 3 minutes or less at least 75% of the time. The secondary hypothesis was that this population would perform all of the tasks considered essential in AED use (establish unresponsiveness, check for breathing, give 2 rescue breaths, check for pulse, apply electrodes correctly, clear patient, activate emergency medical services (EMS) response, and …